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Quantitative Analysis Of Neuroanatomy
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Book Synopsis Quantitative analysis of neuroanatomy by : Julian M L Budd
Download or read book Quantitative analysis of neuroanatomy written by Julian M L Budd and published by Frontiers Media SA. This book was released on 2016-03-22 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The true revolution in the age of digital neuroanatomy is the ability to extensively quantify anatomical structures and thus investigate structure-function relationships in great detail. Large-scale projects were recently launched with the aim of providing infrastructure for brain simulations. These projects will increase the need for a precise understanding of brain structure, e.g., through statistical analysis and models. From articles in this Research Topic, we identify three main themes that clearly illustrate how new quantitative approaches are helping advance our understanding of neural structure and function. First, new approaches to reconstruct neurons and circuits from empirical data are aiding neuroanatomical mapping. Second, methods are introduced to improve understanding of the underlying principles of organization. Third, by combining existing knowledge from lower levels of organization, models can be used to make testable predictions about a higher-level organization where knowledge is absent or poor. This latter approach is useful for examining statistical properties of specific network connectivity when current experimental methods have not yet been able to fully reconstruct whole circuits of more than a few hundred neurons.
Book Synopsis Diffusion MRI by : Heidi Johansen-Berg
Download or read book Diffusion MRI written by Heidi Johansen-Berg and published by Academic Press. This book was released on 2013-11-04 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. - Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging - Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments - New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain - Provides practical advice on running an experiment - Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience - Full color throughout
Book Synopsis Computational Neuroanatomy by : Giorgio A. Ascoli
Download or read book Computational Neuroanatomy written by Giorgio A. Ascoli and published by Springer Science & Business Media. This book was released on 2002-07-01 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models.
Book Synopsis Quantitative Methods in Neuroanatomy by : Michael G. Stewart
Download or read book Quantitative Methods in Neuroanatomy written by Michael G. Stewart and published by . This book was released on 1992-06-16 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and up-to-date reference that deals with methods of evaluation of structure and function of the nervous system, both in vitro and in vivo. Part I considers in vitro and ex vivo applications, beginning with the fundamentals of the autoradiographic technique followed by autoradiography and image analysis. Part II discusses several of the latest methods used in evaluating cerebral structure and function in vivo and recent advances in PET, magnetic resonance imaging and biomagnetism. Part III examines applications for quantification of the components of neurons and synapses and considers two- and three-dimensional methods of neuronal reconstruction. Also features the latest advances in stereology.
Book Synopsis Neuroanatomical Research Techniques by : Richard T. Robertson
Download or read book Neuroanatomical Research Techniques written by Richard T. Robertson and published by Academic Press. This book was released on 2013-10-22 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroanatomical Research Techniques discusses developments in major neuroanatomical research techniques. The book is organized into four parts. Part I deals generally with the preparation and study of brain tissue. It includes a chapter on the microscope, discussing optical magnification, limitations of microscopy, and optical contrasting methods. Other chapters summarize basic techniques for tissue preparation and sectioning; present guidelines for a number of standard, but essential, staining procedures; and present sophisticated and contemporary computer techniques that are proving to be invaluable as neuroanatomy evolves from a qualitative to a quantitative discipline. Part II deals with techniques often used for the study of normal tissue. These include the Golgi method, fluorescence histochemistry, techniques for staining single neurons, and the use of the electron microscope. Part III presents techniques for studying intrinsic connections of the nervous system. These include techniques for silver impregnation of degenerating fibers; autoradiographic technique for studying axonal projections; and somatopetal movement of horseradish peroxidase as a tool for studying connections and neuron morphology. Part IV discusses the interpretation of results from neuroanatomical research techniques and presents examples of the applications of neuroanatomical methods to major problems in physiological psychology.
Book Synopsis Quantitative Neuroanatomy in Transmitter Research by : Luigi F. Agnati
Download or read book Quantitative Neuroanatomy in Transmitter Research written by Luigi F. Agnati and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Experimental Neuroanatomy by : J. P. Bolam
Download or read book Experimental Neuroanatomy written by J. P. Bolam and published by Oxford University Press, USA. This book was released on 1992 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to the most important and up-to-date techniques used in experimental neuroanatomy. It should be of use to anyone wishing to apply these important techniques, especially neuroscientists and neuroanatomists.
Book Synopsis Neuroanatomy of Language Regions of the Human Brain by : Michael Petrides
Download or read book Neuroanatomy of Language Regions of the Human Brain written by Michael Petrides and published by Academic Press. This book was released on 2013-12-03 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many studies of the neural bases of language processes are now conducted with functional and structural neuroimaging. Research is often compromised because of difficulties in identifying the core structures in the face of the complex morphology of these regions of the brain. Although there are many books on the cognitive aspects of language and also on neurolinguistics and aphasiology, Neuroanatomy of Language Regions of the Human Brain is the first anatomical atlas that focuses on the core regions of the cerebral cortex involved in language processing. This atlas is a richly illustrated guide for scientists interested in the gross morphology of the sulci and gyri of the core language regions, in the cytoarchitecture of the relevant cortical areas, and in the connectivity of these areas. Data from diffusion MRI and resting-state connectivity are integrated iwth critical experimental anatomical data about homologous areas in the macaque monkey to provide the latest information on the connectivity of the language-relevant cortical areas of the brain. Although the anatomical connectivity data from studies on the macaque monkey provide the most detailed information, they are often neglected because of difficulties in interpreting the terminology used and in making the monkey-to-human comparison. This atlas helps investigators interpret this important source of information. Neuroanatomy of Language Regions of the Human Brain will assist investigators of the neural bases of language in increasing the anatomical sophistication of their research adn in evaluating studies of language and the brain. - Abundantly illustrated with photographs, 3-D MRI reconstructions, and sections to represent the morphology of the sulci and gyri in the frontal, temporal, and parietal regions involved in language processing - Photomicrographs showing the cytoarchitecture of cortical areas involved in language processing - Series of coronal, sagittal, and horizontal sections identifying the sulci and gyri to assist language investigators using structural and functional neuroimaging techniques - All images accompanied by brief commentaries to help users navigate the complexities of the anatomy - Integration of data from diffusion MRI and resting-state connectivity with critical experimental anatomical data on the connectivity of homologous areas in the macaque monkey
Book Synopsis Statistical and Computational Methods in Brain Image Analysis by : Moo K. Chung
Download or read book Statistical and Computational Methods in Brain Image Analysis written by Moo K. Chung and published by CRC Press. This book was released on 2013-07-23 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: The massive amount of nonstandard high-dimensional brain imaging data being generated is often difficult to analyze using current techniques. This challenge in brain image analysis requires new computational approaches and solutions. But none of the research papers or books in the field describe the quantitative techniques with detailed illustrations of actual imaging data and computer codes. Using MATLAB® and case study data sets, Statistical and Computational Methods in Brain Image Analysis is the first book to explicitly explain how to perform statistical analysis on brain imaging data. The book focuses on methodological issues in analyzing structural brain imaging modalities such as MRI and DTI. Real imaging applications and examples elucidate the concepts and methods. In addition, most of the brain imaging data sets and MATLAB codes are available on the author’s website. By supplying the data and codes, this book enables researchers to start their statistical analyses immediately. Also suitable for graduate students, it provides an understanding of the various statistical and computational methodologies used in the field as well as important and technically challenging topics.
Book Synopsis Stereology for Biological Research by : Jack Glaser
Download or read book Stereology for Biological Research written by Jack Glaser and published by MBF Press. This book was released on 2007 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Neurobiological Basis of Suicide by : Yogesh Dwivedi
Download or read book The Neurobiological Basis of Suicide written by Yogesh Dwivedi and published by CRC Press. This book was released on 2012-06-25 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Book Synopsis Guide to Research Techniques in Neuroscience by : Matt Carter
Download or read book Guide to Research Techniques in Neuroscience written by Matt Carter and published by Academic Press. This book was released on 2022-03-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step
Book Synopsis Atlas of Human Brain Connections by : Marco Catani
Download or read book Atlas of Human Brain Connections written by Marco Catani and published by Oxford University Press, USA. This book was released on 2012-06-14 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major challenges of modern neuroscience is to define the complex pattern of neural connections that underlie cognition and behaviour. This atlas capitalises on novel diffusion MRI tractography methods to provide a comprehensive overview of connections derived from virtual in vivo tractography dissections of the human brain.
Book Synopsis Human Brain Anatomy in Computerized Images by : Hanna Damasio M.D.
Download or read book Human Brain Anatomy in Computerized Images written by Hanna Damasio M.D. and published by Oxford University Press. This book was released on 2005-03-24 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: By using non-invasive tomographic scans, modern neuroimaging technologies are revealing the structure of the human brain in unprecedented detail. This spectacular progress, however, poses a critical problem for neuroscientists and for practitioners of brain-related professions: how to find their way in the current tomographic images so as to identify a particular brain site, be it normal or damaged by disease? Prepared by a leading expert in advanced brain-imaging techniques, this unique atlas is a guide to the localization of brain structures that illustrates the wide range of neuroanatomical variation. It is based on the analysis of 29 normal human brains obtained from three-dimensional reconstructions of magnetic resonance scans of living persons. The Second Edition of this atlas offers entirely new images, all from new brain specimens.
Book Synopsis Micro-, Meso- and Macro-Connectomics of the Brain by : Henry Kennedy
Download or read book Micro-, Meso- and Macro-Connectomics of the Brain written by Henry Kennedy and published by Springer. This book was released on 2016-03-10 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Book Synopsis Introduction to Neuroimaging Analysis by : Mark Jenkinson
Download or read book Introduction to Neuroimaging Analysis written by Mark Jenkinson and published by Oxford University Press. This book was released on 2018 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This accessible primer gives an introduction to the wide array of MRI-based neuroimaging methods that are used in research. It provides an overview of the fundamentals of what different MRI modalities measure, what artifacts commonly occur, the essentials of the analysis, and common 'pipelines'.
Book Synopsis Computational Neuroanatomy by : Moo K. Chung
Download or read book Computational Neuroanatomy written by Moo K. Chung and published by World Scientific. This book was released on 2013 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational neuroanatomy is an emerging field that utilizes various non-invasive brain imaging modalities, such as MRI and DTI, in quantifying the spatiotemporal dynamics of the human brain structures in both normal and clinical populations. This discipline emerged about twenty years ago and has made substantial progress in the past decade. The main goals of this book are to provide an overview of various mathematical, statistical and computational methodologies used in the field to a wide range of researchers and students, and to address important yet technically challenging topics in further detail.
