Quantitative analysis of neuroanatomy

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Publisher : Frontiers Media SA
ISBN 13 : 2889197964
Total Pages : 246 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Quantitative analysis of neuroanatomy by : Julian M L Budd

Download or read book Quantitative analysis of neuroanatomy written by Julian M L Budd and published by Frontiers Media SA. This book was released on 2016-03-22 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The true revolution in the age of digital neuroanatomy is the ability to extensively quantify anatomical structures and thus investigate structure-function relationships in great detail. Large-scale projects were recently launched with the aim of providing infrastructure for brain simulations. These projects will increase the need for a precise understanding of brain structure, e.g., through statistical analysis and models. From articles in this Research Topic, we identify three main themes that clearly illustrate how new quantitative approaches are helping advance our understanding of neural structure and function. First, new approaches to reconstruct neurons and circuits from empirical data are aiding neuroanatomical mapping. Second, methods are introduced to improve understanding of the underlying principles of organization. Third, by combining existing knowledge from lower levels of organization, models can be used to make testable predictions about a higher-level organization where knowledge is absent or poor. This latter approach is useful for examining statistical properties of specific network connectivity when current experimental methods have not yet been able to fully reconstruct whole circuits of more than a few hundred neurons.

Quantitative Methods in Neuroscience

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Publisher : Oxford University Press, USA
ISBN 13 : 0198505280
Total Pages : 349 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Quantitative Methods in Neuroscience by : Stephen M. Evans

Download or read book Quantitative Methods in Neuroscience written by Stephen M. Evans and published by Oxford University Press, USA. This book was released on 2004 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereology is a valuable tool for scientists, allowing them to make 3-D reconstructions of the brain from 2-D data. This is a 'cookbook' of stereological methods written especially for neuroscientists, with clear advice about when and when not to use stereology

Quantitative Methods in Neuroanatomy

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Publisher :
ISBN 13 :
Total Pages : 380 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Quantitative Methods in Neuroanatomy by : Michael G. Stewart

Download or read book Quantitative Methods in Neuroanatomy written by Michael G. Stewart and published by . This book was released on 1992-06-16 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and up-to-date reference that deals with methods of evaluation of structure and function of the nervous system, both in vitro and in vivo. Part I considers in vitro and ex vivo applications, beginning with the fundamentals of the autoradiographic technique followed by autoradiography and image analysis. Part II discusses several of the latest methods used in evaluating cerebral structure and function in vivo and recent advances in PET, magnetic resonance imaging and biomagnetism. Part III examines applications for quantification of the components of neurons and synapses and considers two- and three-dimensional methods of neuronal reconstruction. Also features the latest advances in stereology.

Quantitative Neuroanatomy in Transmitter Research

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Publisher : Springer Science & Business Media
ISBN 13 : 1461321395
Total Pages : 416 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Quantitative Neuroanatomy in Transmitter Research by : Luigi F. Agnati

Download or read book Quantitative Neuroanatomy in Transmitter Research written by Luigi F. Agnati and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Magnetic Resonance Scanning and Epilepsy

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Publisher : Springer Science & Business Media
ISBN 13 : 1461525462
Total Pages : 297 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Magnetic Resonance Scanning and Epilepsy by : Simon D. Shorvon

Download or read book Magnetic Resonance Scanning and Epilepsy written by Simon D. Shorvon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: It was only in 1980 that the first recognisable magnetic resonance images of the human brain were published, by Moore and Holland from Nottingham University in England. There then followed a number of clinical trials of brain imaging, the most notable from the Hammersmith Hospital in London using a system designed by EMI, the original manufacturers of the first CT machines. A true revolution in medicine has ensued; in only a few years there are thousands of scanning units, and magnetic resonance imaging (MRI) has assumed a central importance in medical investigation. It is an extraordinary fact that within a few years of development, the esoteric physics of nuclear spin, angular momentum, and magnetic vector precession were harnessed to provide exquisite images of living anatomy; modem science has no greater tribute. That indisputable king of neurology and the oldest of recorded conditions, epilepsy, has not been untouched by the new technology; indeed, it is our view that the introduction of MRI of electroencephalography (EEG) in the late has been as important to epilepsy as was that 1930s. Now, for the first time, the structural and aetiological basis of the condition is susceptible to thorough investigation, and MRI can provide structural detail to parallel the functional detail of EEG. MRI has the same potential as had EEG over 50 years ago, to provide a new level of understanding of the basic mechanisms, the clinical features and the treatment of epilepsy.

Diffusion MRI

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Publisher : Academic Press
ISBN 13 : 0124055095
Total Pages : 627 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Diffusion MRI by : Heidi Johansen-Berg

Download or read book Diffusion MRI written by Heidi Johansen-Berg and published by Academic Press. This book was released on 2013-11-04 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain Provides practical advice on running an experiment Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience Full color throughout

Computational Neuroanatomy

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Publisher : World Scientific
ISBN 13 : 9814472816
Total Pages : 420 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Computational Neuroanatomy by : Moo K Chung

Download or read book Computational Neuroanatomy written by Moo K Chung and published by World Scientific. This book was released on 2012-09-05 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational neuroanatomy is an emerging field that utilizes various non-invasive brain imaging modalities, such as MRI and DTI, in quantifying the spatiotemporal dynamics of the human brain structures in both normal and clinical populations. This discipline emerged about twenty years ago and has made substantial progress in the past decade. The main goals of this book are to provide an overview of various mathematical, statistical and computational methodologies used in the field to a wide range of researchers and students, and to address important yet technically challenging topics in further detail. Contents:Statistical PreliminaryDeformation-Based MorphometryTensor-Based MorphometryVoxel-Based MorphometryGeometry of Cortical ManifoldsSmoothing on Cortical ManifoldsSurface-Based MorphometryWeighted Fourier RepresentationStructural Brain ConnectivityTopological Data Analysis Readership: Researchers and graduate students in the fields of computational neuroscience and brain imaging, medical image analysis and pattern recognition. Keywords:Computational Neuroanatomy;Brain Image Analysis;NeuroimageKey Features:Includes necessary and very practical mathematical and statistical methodologiesAccessible to a wide range of readers and provides methodological understanding in a manner immediately usable to researchersCovers various topics in great detail without sacrificing readability; it can be used as both a textbook for graduate students and a reference for researchers Reviews: "The book is a comprehensive treatise on computational neuroanatomy — an area that has emerged with the enormous advancements of magnetic resonance imaging (MRI). The book is a solid and evidently needed testimony to the recent developments in the area of computational neuroanatomy. It is a welcome publication, which may appeal to senior graduate students, researchers and practitioners." Zentralblatt MATH

Computational Neuroanatomy

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Publisher : Springer Science & Business Media
ISBN 13 : 1592592759
Total Pages : 466 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Computational Neuroanatomy by : Giorgio A. Ascoli

Download or read book Computational Neuroanatomy written by Giorgio A. Ascoli and published by Springer Science & Business Media. This book was released on 2002-07-01 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models.

Neuroanatomical Research Techniques

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Publisher : Academic Press
ISBN 13 : 1483266400
Total Pages : 462 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Neuroanatomical Research Techniques by : Richard T. Robertson

Download or read book Neuroanatomical Research Techniques written by Richard T. Robertson and published by Academic Press. This book was released on 2013-10-22 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroanatomical Research Techniques discusses developments in major neuroanatomical research techniques. The book is organized into four parts. Part I deals generally with the preparation and study of brain tissue. It includes a chapter on the microscope, discussing optical magnification, limitations of microscopy, and optical contrasting methods. Other chapters summarize basic techniques for tissue preparation and sectioning; present guidelines for a number of standard, but essential, staining procedures; and present sophisticated and contemporary computer techniques that are proving to be invaluable as neuroanatomy evolves from a qualitative to a quantitative discipline. Part II deals with techniques often used for the study of normal tissue. These include the Golgi method, fluorescence histochemistry, techniques for staining single neurons, and the use of the electron microscope. Part III presents techniques for studying intrinsic connections of the nervous system. These include techniques for silver impregnation of degenerating fibers; autoradiographic technique for studying axonal projections; and somatopetal movement of horseradish peroxidase as a tool for studying connections and neuron morphology. Part IV discusses the interpretation of results from neuroanatomical research techniques and presents examples of the applications of neuroanatomical methods to major problems in physiological psychology.

Computational Neuroanatomy

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Publisher : World Scientific
ISBN 13 : 9814335436
Total Pages : 424 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Computational Neuroanatomy by : Moo K. Chung

Download or read book Computational Neuroanatomy written by Moo K. Chung and published by World Scientific. This book was released on 2013 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational neuroanatomy is an emerging field that utilizes various non-invasive brain imaging modalities, such as MRI and DTI, in quantifying the spatiotemporal dynamics of the human brain structures in both normal and clinical populations. This discipline emerged about twenty years ago and has made substantial progress in the past decade. The main goals of this book are to provide an overview of various mathematical, statistical and computational methodologies used in the field to a wide range of researchers and students, and to address important yet technically challenging topics in further detail.

Neuroanatomical Tract-Tracing

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Publisher : Springer Science & Business Media
ISBN 13 : 0387289429
Total Pages : 703 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Neuroanatomical Tract-Tracing by : Laszlo Zaborszky

Download or read book Neuroanatomical Tract-Tracing written by Laszlo Zaborszky and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first two editions of this title had a tremendous impact in neuroscience. Between the Second edition in 1989 and today, there has been an explosion of information in the field, including advances in molecular techniques, such as genomics and proteomics, which have become increasing important in neuroscience. A renaissance in fluorescence has occurred, driven by the development of new probes, new microscopes, live imagers, and computer processing. The introduction of new markers has enormously stimulated the field, moving it from tissue culture to neurophysiology to functional MRI techniques.

Quantitative Neuroanatomy in Transmitter Research

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Publisher :
ISBN 13 : 9780333396377
Total Pages : 418 pages
Book Rating : 4.3/5 (963 download)

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Book Synopsis Quantitative Neuroanatomy in Transmitter Research by : Luigi F. Agnati

Download or read book Quantitative Neuroanatomy in Transmitter Research written by Luigi F. Agnati and published by . This book was released on 1985 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computer Techniques in Neuroanatomy

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Publisher : Springer Science & Business Media
ISBN 13 : 1468456911
Total Pages : 497 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Computer Techniques in Neuroanatomy by : J.J. Capowski

Download or read book Computer Techniques in Neuroanatomy written by J.J. Capowski and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the story of the marriage of a new techl}ology, computers, with an old problem, the study of neuroanatomical structures using the light microscope. It is aimed toward you, the neuroanatomist, who until now have used computers primarily for word processing but now wish to use them also to collect and analyze your laboratory data. Mter reading the book, you will be better equipped to use a computer system for data collection and analysis, to employ a programmer who might develop a system for you, or to evaluate the systems available in the marketplace. To start toward this goal, a glossary first presents commonly used terms in computer assisted neuroanatomy. This, on its own, will aid you as it merges the jargon of the two different fields. Then, Chapter 1 presents a historical review to describe the manual tasks involved in presenting and measuring anatomic structures. This review lays a base line of the tasks that were done before computers and the amount of skill and time needed to perform the tasks. In Chapters 2 and 3, you will find basic information about laboratory computers and programs to the depth required for you to use the machines easily and talk with some fluency to computer engineers, programmers, and salesmen. Chapters 4, 5, and 6 present the use of computers to reconstruct anatomic structures, i.e., to enter them into a computer memory, where they are later displayed and analyzed.

Cortex: Statistics and Geometry of Neuronal Connectivity

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Publisher : Springer
ISBN 13 : 9783662037355
Total Pages : 249 pages
Book Rating : 4.0/5 (373 download)

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Book Synopsis Cortex: Statistics and Geometry of Neuronal Connectivity by : Valentino Braitenberg

Download or read book Cortex: Statistics and Geometry of Neuronal Connectivity written by Valentino Braitenberg and published by Springer. This book was released on 2012-11-01 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: By means of quantitative analysis of the tissue components in the cortex of the mouse, this book presents an overall picture of the cortical network which is then related to various theories on cortical function. Centering around the idea of a diffuse network in a fairly homogeneous population of excitatory neurons, that of the pyramidal cells, it shows that the whole organisation in the cortical skeleton of pryramidal cells corresponds well with the idea of an associative memory and with the theory of cell assemblies. Provides the reader with information on quantitative neuroanatomy and also on the methods used, in particular those that vary from the norm.

Techniques in Neuroanatomical Research

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Publisher : Springer Science & Business Media
ISBN 13 : 3642680291
Total Pages : 405 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Techniques in Neuroanatomical Research by : C. Heym

Download or read book Techniques in Neuroanatomical Research written by C. Heym and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Anatomy is the mother of physiology" - this statement was used to characterize the evolution of physiology from anato my as an independent science in the late nineteenth century. It had particular truth for neurophysiology, which started as functional neuroanatomy based on the observation of changes in behaviour after lesions of the nervous system both in ex perimental animals and in human patients. Today, anatomy may again be considered the mother of physiology; however, the meaning of this statement is rather different from that 100 years ago: The modem mother provides a dwelling for an increasing number of children endowed with new functional capabilities. This book provides a good illustration of such se mantic metamorphosis in the case of neuroanatomy. After a long period of little progress in either macroscopic neuroanatomy or neurohistology, during which the heritage of Cajal, Golgi, and others was developed and refined to yield a functional concept of the nervous system, the past two de cades have seen tremendous progress in methods applicable to the analysis of the nervous system. The new era was heralded by the introduction of the electron microscope to investigate the nervous system. This book is an impressive witness to the more recent developments.

Neurometric Assessment of Brain Dysfunction in Neurological Patients

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Publisher : Psychology Press
ISBN 13 :
Total Pages : 604 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Neurometric Assessment of Brain Dysfunction in Neurological Patients by : Thalía Harmony

Download or read book Neurometric Assessment of Brain Dysfunction in Neurological Patients written by Thalía Harmony and published by Psychology Press. This book was released on 1984 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1984. Routledge is an imprint of Taylor & Francis, an informa company.

Molecular Neuroanatomy

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Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Neuroanatomy by : Fred W. Leeuwen

Download or read book Molecular Neuroanatomy written by Fred W. Leeuwen and published by Elsevier Publishing Company. This book was released on 1988 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: For a thorough study of the dynamics of particular brain compounds it is now possible to use and combine various molecular neuroanatomical methods (e.g. in situ hybridization, receptor localisation and immunocytochemistry) in a quantitative way on whole brain sections maintaining morphological details. Molecular Neuroanatomy deals with the many practical aspects and recent developments in these areas. The theoretical background of many techniques is presented, as well as clear, step-by-step instructions on the preparation and application of all the methods and techniques described in this book. It will be invaluable to all those working in the field of neuroscience. Available in both hardback and paperback, with colour illustrations.