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Quality Assurance For Design Control And Implementation Of Immunohistochemistry Assays Approved Guideline
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Book Synopsis Handbook of Practical Immunohistochemistry by : Fan Lin
Download or read book Handbook of Practical Immunohistochemistry written by Fan Lin and published by Springer Nature. This book was released on 2022-06-14 with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt: As in the second edition, the third edition of Handbook of Practical Immunohistochemistry – Frequently Asked Questions is written in a question and answer (Q&A) format and intended to be a practical, user-friendly, quick reference for information related to using the most up-to-date immunohistochemistry and in situ hybridization in clinical diagnosis. The new edition demonstrates a significant revision and improvement over the second edition. Five new chapters have been added that cover the following: 1) Immunohistochemistry: Leica’s perspective; 2) Immunohistochemistry: Maixin perspective; 3) RNA in situ hybridization: Applications in anatomic pathology; 4) Applications of rapid immunohistochemistry on frozen tissue sections during intraoperative pathologic diagnosis; and 5) Cutaneous lymphomas. In addition to extensive additions and changes, over 150 new questions and answers were added throughout this new edition. All chapters have been updated to include relevant new questions, new markers, more refined IHC panels, representative pictures, and current references. An extensive set of high-quality color pictures and diagnostic algorithms, if available, is included in each chapter to illustrate some of the key antibodies, including many recently discovered and substantiated antibodies used in that chapter. Written by experts in the field, Handbook of Practical Immunohistochemistry Third Edition is a comprehensive and practical guide for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.
Book Synopsis Immunohistochemistry by : Charles Streckfus
Download or read book Immunohistochemistry written by Charles Streckfus and published by BoD – Books on Demand. This book was released on 2020-03-04 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunohistochemistry - The Ageless Biotechnology is a book that is ideal for undergraduate and graduate biomedical researchers, and medical and dental health professionals. It is a detailed text, which emphasizes the laboratory and clinical implications of immunohistochemistry. The text covers the advances of immunohistochemistry from its humble origins in the 1930s up to the new decade of 2020. The book also offers a review of the immunohistochemistry detection systems with emphasis on their principles, history, and their advantages. It also stipulates the limitations and delineates the factors that need to be considered for choosing an appropriate detection system for IHC applications. The book describes current laboratory techniques and new applications for the technology. As the reader will observe, the book provides new and useful information concerning the rapidly advancing field of immunohistochemistry.
Book Synopsis Diagnostic Immunohistochemistry E-Book by : David J Dabbs
Download or read book Diagnostic Immunohistochemistry E-Book written by David J Dabbs and published by Elsevier Health Sciences. This book was released on 2017-11-29 with total page 1145 pages. Available in PDF, EPUB and Kindle. Book excerpt: User-friendly and concise, the new edition of this popular reference is your #1 guide for the appropriate use of immunohistochemical stains. Dr. David J. Dabbs and leading experts in the field use a consistent, organ system approach to cover all aspects of the field, with an emphasis on the role of genomics in diagnosis and theranostic applications that will better inform treatment options. Each well-written and well-researched chapter is enhanced with diagnostic algorithms, charts, tables, and superb, full-color histologic images, making this text a practical daily resource for all surgical pathologists. Features a systematic approach to the diagnostic entities of each organ system, including detailed differential diagnoses, diagnostic algorithms, and immunohistograms that depict immunostaining patterns of tumors. Covers many more antigens than other texts, and discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Contains new material on non-lymphoid malignancies, Hodgkin/non-Hodgkin lymphoma, and an expanded chapter on digital imaging and quantitative immunohistochemistry. Provides new grading schemes for several organs, along with new antibodies to cover more genomic immunohistochemistry applications. Offers more emphasis in the breast section of "eyes on" tissue for molecular/IHC prognostics compared to the current trend of gene-expression profiling of breast cancer. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Book Synopsis Essentials of Anatomic Pathology by : Liang Cheng
Download or read book Essentials of Anatomic Pathology written by Liang Cheng and published by Springer. This book was released on 2016-02-13 with total page 2103 pages. Available in PDF, EPUB and Kindle. Book excerpt: This much praised and widely used reference manual on has been extensively revised and expanded to cover the entire field of anatomic pathology. The Fourth Edition features the incorporation of full-color images in the text with updates of new diagnostic and prognostic information. New classifications and numerous new entities and histologic variants for each organ site will be fully incorporate in each individual chapter (Part II Organ Systems). Useful immunostaining biomarkers and emerging molecular targets and relevant molecular findings that have emerged from recent genomic studies are incorporated in each chapter. Written by internationally recognized authorities, the comprehensive, evidence-based practice information is presented in an outline format that is clear and easy to follow. Up-to-date and richly detailed, Essentials of Anatomic Pathology, Fourth Edition offers both the pathologist-in-training and the practicing pathologist a concise summary of all the critical information needed to recognize, understand and interpret anatomic pathology.
Book Synopsis The Washington Manual of Rheumatology Subspecialty Consult by : Peter A. Humphrey
Download or read book The Washington Manual of Rheumatology Subspecialty Consult written by Peter A. Humphrey and published by Lippincott Williams & Wilkins. This book was released on 2012-05-28 with total page 1001 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The aim of this book is to provide a practical manual that is helpful to pathologists and residents in the daily practice of surgical pathology. The text encompasses all anatomic sites in the human body. Each chapter covers tissue handling, gross examination, gross dissection and diagnosis, processing, slide preparation, microscopic diagnosis, special studies, and diagnostic reporting. The format of the book would be modeled after the Washington Manuals for other specialties (such as Medical Therapeutics, Oncology, and Surgery)"--Provided by publisher.
Book Synopsis Molecular Pathology of Breast Cancer by : Sunil Badve
Download or read book Molecular Pathology of Breast Cancer written by Sunil Badve and published by Springer. This book was released on 2016-11-26 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complex landscape of breast cancer requires distinct strategies for the management of various molecular subtypes of this disease. Rapid advances in the field of molecular biology have been bewildering for those involved in its study and management. “Molecular Pathology of Breast Cancer” aims to close this knowledge gap by discussing comprehensively the evolution, biological basis and clinical applications with a focus on the “what, when, and how” of the most significant molecular markers known to date. These markers are evaluated in the context of genomic, transcriptomic and proteomic profiles, which is integral to the practice of precision medicine. The application of next generation sequencing (NGS) has provided new insights in the regulation of genomic and transcriptomic structure and function. Alterations in DNA such as mutations and single nucleotide polymorphisms (SNPs) have been correlated with outcomes and provide for novel therapeutic approaches. These NGS analyses have also revealed the extensive contributions of epigenetic mechanisms such as histone modifications, non-coding RNA and alternative splicing. All of these changes together contribute to alterations in proteome. Newer assays that allow greater stability and analytical consistency are emerging. These alterations in tumor profiles can be also now detected by imaging techniques. The heterogeneity of both tumor and tumor microenvironment, an inevitable reality, is discussed in detail with particular focus on cancer stem cells and immune signaling. A chapter is dedicated to the emerging technology of “liquid biopsy”, which opens a novel approach for “continuous” monitoring of cancer that might be superior to conventional diagnostics, “Molecular Pathology of Breast Cancer” provides a quick and easy, not to mention essential, tour for clinicians, pathologists and scientists who are seeking to understand the integration of molecular biology into the diagnosis, prognosis and management of breast cancer.
Download or read book Sarcoma written by Peter F. M. Choong and published by Springer Nature. This book was released on 2020-12-09 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to compile an expert text on the multidisciplinary approach to treating sarcoma at a sarcoma centre. Separate chapters and sections highlight the specialist diagnostic and therapeutic approaches employed in treating bone and soft tissue sarcoma. This comprehensive book covers sarcoma and its management across specialties. It brings together the experience of the editor at a major centre for sarcoma management in Australia along with chapter contributions from various experts on the topic. The real-life, pragmatic approach is a distillation of the evidence and intends to make much of what is written translatable. This book serves as a reference for managing this tumour type and as an indispensable guide for daily use across the spectrum of providers.
Book Synopsis Companion and Complementary Diagnostics by : Jan Trøst Jørgensen
Download or read book Companion and Complementary Diagnostics written by Jan Trøst Jørgensen and published by Academic Press. This book was released on 2019-05-08 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Companion and Complementary Diagnostics: From Biomarker Discovery to Clinical Implementation provides readers with in-depth insights into the individual steps in the development of companion diagnostic assays, from the early biomarker discovery phase straight through to final regulatory approval. Further, the clinical implementation of companion diagnostic testing in the clinic is also discussed. As the development of predictive or selective biomarker assays linked to specific drugs is substantially increasing, this book offers comprehensive information on this quickly-evolving area of biomedicine. It is an essential resource for those in academic institutions, hospitals and pharma, and biotech and diagnostic commercial companies. - Covers all aspects, from biomarker discovery, to development and regulatory approval - Explains the "how to" aspects of companion diagnostics - Incorporates information on the entire process, allowing for easier and deeper understanding of the topic
Book Synopsis Principles of Perioperative Safety and Efficiency by : Jamal J. Hoballah
Download or read book Principles of Perioperative Safety and Efficiency written by Jamal J. Hoballah and published by Springer Nature. This book was released on 2024 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perioperative safety continues to be a global challenge. It is estimated that approximately 200 million surgical procedures are performed annually worldwide, and despite various national and global safety initiatives, perioperative adverse event rates remain alarmingly high. Although hospitals and governmental agencies impose safety standards and certification by organizations such as the Joint Commission, which can address issues of perioperative safety, many hospitals in developed, developing or underdeveloped countries lack the resources or knowhow to decrease perioperative adverse events. There is a great opportunity for improving perioperative safety worldwide especially in underdeveloped or developing countries. Filling a gap in the literature, this book teaches healthcare providers the basic principles of perioperative safety and efficiency, including checklists and processes to reduce adverse events. Presented here are the basics of intraoperative monitoring and safety measures to reduce patient adverse events, including wrong site surgery, electric burn injury, deep venous thrombosis, surgical site infection and foreign body retention. Emphasis is given toward developing awareness into measures preventing occupational injuries, such as sharp injury, radiation exposure, laser exposure and smoke hazard. It also addresses dealing and reporting adverse events and disruptive behaviors in the operating rooms as well as new measures for enhanced recovery following surgery and anesthesia. Principles of Perioperative Safety and Efficiency is a valuable resource and reference for all operating room personnel including surgeons, surgical residents, medical students and nurses.
Book Synopsis Tumors in Domestic Animals by : Donald J. Meuten
Download or read book Tumors in Domestic Animals written by Donald J. Meuten and published by John Wiley & Sons. This book was released on 2016-11-08 with total page 1001 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumors in Domestic Animals, Fifth Edition is a fully revised new edition of the most comprehensive and authoritative reference on veterinary tumor pathology in common domestic animals, now in full color throughout with the most current advances in research and diagnostics. Now in full color with hundreds of exquisite new images showing diagnostic features, pathogenesis, and techniques Adds new sections on relevant clinical pathology and oncology Updated throughout to include the very latest advances in research and diagnostics Takes a logical, user-friendly system approach Written by leading experts on animal tumor pathology
Book Synopsis Methods in Breast Cancer by : Luis Costa
Download or read book Methods in Breast Cancer written by Luis Costa and published by Frontiers Media SA. This book was released on 2023-11-27 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Oncology is delighted to present the Methods in series of article collections. Methods in Breast Cancer will publish high-quality methodical studies on key topics in the field. It aims to highlight recent advances in the field, whilst emphasizing important directions and new possibilities for future inquiries. The Methods in Breast Cancer collection aims to highlight the latest experimental techniques and methods used to investigate fundamental questions in Breast Cancer. Review Articles or Opinion Articles on methodologies or applications including the advantages and limitations of each are welcome. This Research Topic includes technologies and up-to-date methods which help aim to help advance science. Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Book Synopsis Precision Cancer Medicine by : Bharat Jasani
Download or read book Precision Cancer Medicine written by Bharat Jasani and published by Springer Nature. This book was released on 2022-01-04 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the changing role of pathology in aiding reproducible and accurate patient selection for predictive cancer therapy. Particular attention is given to the clinical application of cutting-edge cancer biomarkers to accurately select patients for targeted cancer therapy and how artificial intelligence can improve the precision of treatments. The advent and basis of predictive cancer care, the role of pathologists in translational cancer research, the analysis of cancer samples, the management of biopsy results, and the accuracy of biopsy results are also discussed. Precision Cancer Medicine: Role of the Pathologist details how pathologists can use the latest biomarkers and apply artificial intelligence technology in cancer diagnosis and management. It is also relevant to oncologists and medical practitioners involved in cancer management seeking an up-to-date resource on the topic.
Book Synopsis Spontaneous Pathology of the Laboratory Non-human Primate by : Alys Bradley
Download or read book Spontaneous Pathology of the Laboratory Non-human Primate written by Alys Bradley and published by Academic Press. This book was released on 2023-06-20 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spontaneous Pathology of the Laboratory Non-human Primate serves as a "go to" resource for all pathologists working on primates in safety assessment studies. In addition, it helps diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathologies when assigning cause of death to species in zoological collections. Primate species included are rhesus, cynomolgus macaques and marmosets. Multi-authored chapters are arranged by organ system, thus providing the necessary information for continued research.Pathologists often face a lack of suitable reference materials or historical data to determine if pathologic changes they are observing in monkeys are spontaneous or a consequence of other treatments or factors. - Contains color illustrations that depict the most common lesions to augment descriptions - Covers descriptions that are compliant with the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) guidelines set forth by the Society of Toxicologic Pathology (STP) - Provides pathologists with common terms that are compliant with the FDA's Standard for Exchange of Nonclinical Data (SEND) guidelines
Book Synopsis Error Reduction and Prevention in Surgical Pathology by : Raouf E. Nakhleh
Download or read book Error Reduction and Prevention in Surgical Pathology written by Raouf E. Nakhleh and published by Springer. This book was released on 2019-07-09 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 1st edition of Error Reduction and Prevention in Surgical Pathology was an opportunity to pull together into one place all the ideas related to errors in surgical pathology and to organize a discipline in error reduction. This 2nd edition is an opportunity to refine this information, to reorganize the book to improve its usability and practicality, and to include topics that were not previously addressed. This book serves as a guide to pathologists to successfully avoid errors and deliver the best diagnosis possible with all relevant information needed to manage patients. The introductory section includes general principles and ideas that are necessary to understand the context of error reduction. In addition to general principles of error reduction and legal and regulatory responsibilities, a chapter on regulatory affairs and payment systems which increasingly may be impacted by error reduction and improvement activities was added. This later chapter is particularly important in view of the implementation of various value-based payment programs, such as the Medicare Merit-Based Incentive Payment System that became law in 2015. The remainder of the book is organized in a similar manor to the 1st edition with chapters devoted to all aspects of the test cycle, including pre-analytic, analytic and post-analytic. The 2nd Edition of Error Reduction and Prevention in Surgical Pathology serves as an essential guide to a successfully managed laboratory and contains all relevant information needed to manage specimens and deliver the best diagnosis.
Book Synopsis Rosai and Ackerman's Surgical Pathology E-Book by : Juan Rosai
Download or read book Rosai and Ackerman's Surgical Pathology E-Book written by Juan Rosai and published by Elsevier Health Sciences. This book was released on 2011-06-20 with total page 2767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rosai and Ackerman’s Surgical Pathology delivers the authoritative guidance you need to overcome virtually any challenge in surgical pathology. Recognized globally for his unmatched expertise, preeminent specialist Juan Rosai, MD brings you state-of-the-art coverage of the latest advancements in immunohistochemistry, genetics, molecular biology, prognostic/predictive markers, and much more - equipping you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities. Efficiently review the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, differential diagnosis, therapy, and prognosis for virtually every pathologic entity. Compare your findings to more than 3,300 outstanding illustrations that capture the characteristic presentation of every type of lesion. Avoid diagnostic pitfalls using Dr. Rosai's expert observations on what to look for, what to be careful about, and which presentations can be misleading. Find quick answers on tumor staging, quality control procedures, and the handling of gross specimens through valuable appendices. Make optimal use of all the very latest advances including our increased understanding of the genetic basis of inherited and acquired disease, the newest molecular genetic and immunohistochemical techniques, and the most recent WHO disease classification schemes.
Book Synopsis Renal Cell Carcinoma by : Robert A. Figlin
Download or read book Renal Cell Carcinoma written by Robert A. Figlin and published by Springer Science & Business Media. This book was released on 2012-03-01 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive look at renal cell carcinoma, exploring its biology as well as current and future molecular targets for renal cancer carcinoma.
Book Synopsis Diagnostic Immunohistochemistry by : David J. Dabbs
Download or read book Diagnostic Immunohistochemistry written by David J. Dabbs and published by . This book was released on 2002 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: 17 world-renowned experts offer the most current information and reliable guidance on immunohistochemical diagnoses in surgical pathology and cytopathology. Introductory chapters cover cost modeling for immunohistochemistry and immunohistochemical techniques. The following chapters utilize an organ systems and diseases approach to diagnostic tumor pathology. "A newly updated book that our laboratory staff have found very useful in our day to day work" Reviewed by: PathLab.org, Sept 2014 "...It also acts as an up-to-date bench-top reference tool. It is an easy-to-read, wellpresented text that I would recommend as a 'must have' for every pathology department". Reviewed by: Dr Gemma Petts, Imperial College London on behalf of The Bulletin of The Royal College of Pathologists, Oct 2014 Consistently organized chapters for quick access to vital information Each chapter "stands alone," providing all the information you might need on a specific topic Quick-reference boxes summarize the most important diagnostic points at the end of each text Section Colour photographs and illustrations reinforce key diagnostic points
