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Purinergic Signaling 2020 The State Of The Art Commented By The Members Of The Italian Purine Club
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Book Synopsis Purinergic Signaling 2020: the State-of-The-Art Commented by the Members of the Italian Purine Club by : Francesco Caciagli
Download or read book Purinergic Signaling 2020: the State-of-The-Art Commented by the Members of the Italian Purine Club written by Francesco Caciagli and published by Frontiers Media SA. This book was released on 2021-10-29 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Purinergic Signalling and the Nervous System by : Geoffrey Burnstock
Download or read book Purinergic Signalling and the Nervous System written by Geoffrey Burnstock and published by Springer Science & Business Media. This book was released on 2012-06-05 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the first 20 years that followed the purinergic signalling hypothesis in 1972, most scientists were sceptical about its validity, largely because ATP was so well established as an intracellular molecule involved in cell biochemistry and it seemed unlikely that such a ubiquitous molecule would act as an extracellular signalling molecule. However, after the receptors for ATP and adenosine were cloned and characterized in the early 1990s and ATP was established as a synaptic transmitter in the brain and sympathetic ganglia, the tide turned. More recently it has become clear that ATP is involved in long-term (trophic) signalling in cell proliferation, differentiation and death, in development and regeneration, as well as in short-term signalling in neurotransmission and secretion. Also, important papers have been published showing the molecular structure of P2X receptors in primitive animals like Amoeba and Schistosoma, as well as green algae. This has led to the recognition of the widespread nature of the purinergic signalling system in most cell types and to a rapid expansion of the field, including studies of the pathophysiology as well as physiology and exploration of the therapeutic potential of purinergic agents. In two books, Geoffrey Burnstock and Alexej Verkhratsky have aimed at drawing together the massive and diverse body of literature on purinergic signalling. The topic of this first book is purinergic signalling in the peripheral and central nervous systems and in the individual senses. In a second book the authors focus on purinergic signalling in non-excitable cells, including those of the airways, kidney, pancreas, endocrine glands and blood vessels. Diseases related to these systems are also considered.
Book Synopsis Introduction to Basics of Pharmacology and Toxicology by : Abialbon Paul
Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.
Book Synopsis In Praise Of Imperfe by : Rita Levi-Montalcini
Download or read book In Praise Of Imperfe written by Rita Levi-Montalcini and published by . This book was released on 1988-05-08 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: The autobiography of Levi-Montalcini, who won the Nobel Prize for Medicine in 1986. Born in Torino into a middle-class Jewish family, she experienced the rise of fascism and antisemitism in the 1930s-40s (discussed on pp. 73-105). After the promulgation of the racial laws in 1938, it was impossible for her to pursue research at the Neurological Clinic and she continued her work in private. She survived the war hiding in a small town in Italy and later emigrated to the United States.
Book Synopsis Perspectives of Stem Cells by : Henning Ulrich
Download or read book Perspectives of Stem Cells written by Henning Ulrich and published by Springer Science & Business Media. This book was released on 2010-01-14 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells are fascinating cell types. They can replicate themselves forever while retaining the potential to generate progeny with speci?c functions. Because of these special properties, stem cells have been subjects of intensive investigation, from understanding basic mechanisms underlying tissue generation, to modeling human diseases, to application for cell replacement therapy. Stem cells come in different forms. For example, mouse embryonic stem cells can general all cell types in a body, either in a dish or when put back into mouse embryos. On the other hand, neural stem cells in the adult brain generate neurons and glia cells that contribute to the brain’s plasticity. Rapid progress has been made in the stem cell ?eld with discov- ies published in a record speed. A quick Pubmed search has returned 2789 hits for “embryonic stem cells” and 815 hits for “adult neural stem cells/neurogenesis” in the year 2008 alone. It remains a taunting task for all who are interested in stem cells to keep up with rapidly accumulating literatures. The “Perspectives of Stem Cells” by a truly international team of experts provides a timely and invaluable highlight of the stem cell ?eld gearing toward future therapeutic applications in the nervous system. Stem cells with neural potentials have attracted a lot of attention because of their promise for cell replacement therapy, ranging from degenerative neurological dis- ders to spinal cord injuries.
Download or read book Cytometry, Part A written by and published by Elsevier. This book was released on 2000-10-31 with total page 683 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each chapter presents a detailed background of the described method, its theoretical foundations, and its applicability to different biomedical material. Updated chapters describe either the most popular methods or those processes that have evolved the most since the past edition. Additionally, a large portion of the volume is devoted to clinical cytometry. Particular attention is paid to applications of cytometry in oncology, the most rapidly growing area. Contains 56 extensive chapters authored by world authorities on cytometry Covers a wide range of topics, including principles of cytometry and general methods, cell preparation, tandardization and quality assurance, cell proliferation, apoptosis, cell-cell/cell-environmental interactions, cytogenetics and molecular genetics, cell function and differentiation, experimental and clinical oncology, microorganisms, and infectious diseases Describes in-depth the essential methods and scientific principles of flow and laser scanning cytometry and illustrates how they can be applied to the fields of biology and medicine Complements the first and second editions on flow cytometry in the Methods in Cell Biology series and includes new sections on technology principles
Book Synopsis P-adic Aspects Of Modular Forms by : Baskar Balasubramanyam
Download or read book P-adic Aspects Of Modular Forms written by Baskar Balasubramanyam and published by World Scientific. This book was released on 2016-06-14 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to give a systematic exposition of results in some important cases where p-adic families and p-adic L-functions are studied. We first look at p-adic families in the following cases: general linear groups, symplectic groups and definite unitary groups. We also look at applications of this theory to modularity lifting problems. We finally consider p-adic L-functions for GL(2), the p-adic adjoint L-functions and some cases of higher GL(n).
Book Synopsis Childhood Acute Lymphoblastic Leukemia by : Ajay Vora
Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Book Synopsis Molecular Infection Biology by : Jörg Hinrich Hacker
Download or read book Molecular Infection Biology written by Jörg Hinrich Hacker and published by Wiley-Spektrum. This book was released on 2002-10-03 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume focuses on molecular methods and principles of prokaryotic and eukaryotic pathogens. The authors present the molecular and cellular aspects by focusing on the interactions between pathogenic microorganisms and their hosts. The publication begins with an overview of the most important and dangerous causative agents of infectious diseases. Next are discussions of how microbial "weapons," pathogenicity factors, protein secretion machines, and surface variation systems work, presenting the molecular and genetic methods that are used by scientists for their discovery and analysis. Furthermore, infectious diseases are discussed in light of the newly formed research areas of evolutionary and cellular microbiology and genomics. Future aspects on diagnostic techniques, therapy, and vaccine development are also presented.
Book Synopsis Pocket Surgery by : Melanie Goldfarb
Download or read book Pocket Surgery written by Melanie Goldfarb and published by Lippincott Williams & Wilkins. This book was released on 2012-01-18 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prepared by residents and attending physicians at Beth Israel Deaconess Hospital, Pocket Surgery, follows the style of Pocket Medicine, one of the best-selling references for medical students, interns, and residents. This pocket-sized loose-leaf resource can be used on the wards and by candidates reviewing for board exams. In bulleted lists, tables, and algorithms, Pocket Surgery provides key clinical information about common surgical conditions in all areas of surgery, including breast, critical care, cardiothoracic, gastrointestinal, colorectal, vascular, pediatric, plastic, transplant, transplant, and endocrine.
Book Synopsis Disease Pathways by : Anastasia P. Nesterova
Download or read book Disease Pathways written by Anastasia P. Nesterova and published by Elsevier. This book was released on 2019-10-18 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple. Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of molecular signaling biology and application of pathway models in the analysis of big data for drug discovery and personalized medicine. This is a must-have reference for general biologists, biochemists, students, medical workers, and everyone interested in the cellular and molecular mechanisms of human disease. Over 145 full-color illustrations of the molecular and cellular cascades underlying the disease pathology. Disease pathways are based on computational models from Elsevier’s Disease Pathway Collection, published for the first time outside of Pathway Studio® commercial software. Each relationship on the pathway models is supported by references to scientific articles and can be examined at freely available online resources.
Book Synopsis Medicinal Chemistry and Pharmacology by : Avianna Stokes
Download or read book Medicinal Chemistry and Pharmacology written by Avianna Stokes and published by . This book was released on 2019-06-25 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry and pharmacology are closely associated fields. They are concerned with the design and synthesis of drugs for the pharmaceutical industry. These drugs are generally organic compounds and can be divided into classes of biologics and small organic compounds. Medicinal chemistry is focused on the production of small organic molecules such as atorvastatin, fluticasone, clopidogrel, etc. The principles of synthetic organic chemistry, computational chemistry, enzymology, structural biology and chemical biology are integrated in medicinal chemistry. The study of drugs and their effects on the living body are explored in pharmacology. It involves the research, discovery and characterization of the chemicals that exhibit a biological effect. All therapies that are designed to target diseases, defects and pathogens and also advance preventive care, diagnostics and personalized medicine are a result of tremendous research in pharmacology. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the fields of medicinal chemistry and pharmacology. The various advancements in these fields are glanced at and their applications as well as ramifications are looked at in detail. This book is a vital tool for all researching and studying pharmaceutical science and medicinal chemistry.
Book Synopsis Atlas of Robotic Surgery by : Alfredo M. Carbonell
Download or read book Atlas of Robotic Surgery written by Alfredo M. Carbonell and published by . This book was released on 2018-08-30 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Diabetic Foot by : Aristidis Veves
Download or read book The Diabetic Foot written by Aristidis Veves and published by . This book was released on 2014-01-15 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pocket Journal Club: Essential Articles in General Surgery by : Laura M. Mazer
Download or read book Pocket Journal Club: Essential Articles in General Surgery written by Laura M. Mazer and published by McGraw Hill Professional. This book was released on 2016-10-06 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: A combination primer on evaluating the surgical literature and summary of landmark articles in general surgery Pocket Journal Club: Essential Articles in General Surgery is a complete primer on how to efficiently evaluate the surgical literature, conduct literature searches, and identify high-impact articles. It also delivers concise, high-yield summaries of more than 130 of the most important surgical papers of the past few decades. These carefully selected summaries help you better understand the studies that have shaped surgical specialties and continue to inform clinical practice today. Features: • Articles are conveniently arranged by subspecialty fields within general surgery • Each article summary is accompanied by brief commentary explaining the paper’s importance and relevance to current practice • Designed to guide you towards a practice grounded in evidence, and enhance your ability to find and evaluate new information • Essential reading for medical students, surgical trainees, as well as practicing clinicians who want an index of cornerstone literature
Book Synopsis Hearing Impairment and Disability by : Ariel Tenenbaum
Download or read book Hearing Impairment and Disability written by Ariel Tenenbaum and published by . This book was released on 2020 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Much research has been conducted to provide researchers and hearing healthcare professionals with updated information in regard to hearing assessments, results interpretation and case management. This ongoing research is particularly imperative to guide clinicians with optimized methods in assessing and managing pediatric patients with hearing impairment and disability. As such, tremendous research efforts have been made in determining the most optimum methods in assessing hearing using both subjective and objective tests. Since hearing loss can occur due to disrupted peripheral and/or central auditory pathway, there is also a growing interest to study children with auditory processing disorder (APD). Even though notable achievements have been observed in understanding APD, more research is required, particularly in establishing a gold standard APD test and its specific interventions. Aditionally, having an objective test such as speech-evoked auditory brainstem response is beneficial to understand how speech sounds are encoded within the brainstem region in hearing-impaired children, as well as in those with compromised neural function. In this book, we have gathered research from Malaysia and India in this field and hope it will be of interest to our readers"--
Book Synopsis Endocrine Aspects of Cancer by : Kathryn B. Horwitz
Download or read book Endocrine Aspects of Cancer written by Kathryn B. Horwitz and published by . This book was released on 1993 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:
