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Download or read book Purine Metabolism in Man 3 written by and published by . This book was released on 1980 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Oded Sperling
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (923 download)
Download or read book Purine Metabolism in Man written by Oded Sperling and published by . This book was released on 1974 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Chris H. De Bruyn
Publisher : Springer Science & Business Media
ISBN 13 : 1468445537
Total Pages : 533 pages
Book Rating : 4.4/5 (684 download)
Download or read book Purine Metabolism in Man-IV written by Chris H. De Bruyn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes, entitled "Purine Metabolism in Man IV" con tain the paper presented at the "IV. International Symposium on Human Purine and Pyrimidine Metabolism," held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo lism under normal and pathological conditions has been growing rapid ly. Apart from the more or less classical topics such as hyperuricae mia, clinical gout and urolithiasis, an increasing number of papers relating to other fields have been presented at successive meetings. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse quences for other types of cancer. At previous meetings there have been pointers implicating purine metabolism in relation to normal cardiac and skeletal muscle function. During the present meeting much new data on both issues have been re ported which indicate clear differences in the pathways of ATP metabo lism. The widening of the field of interest is also illustrated by the recent work on infectious disease: exploitation of the differences in purine metabolic pathways in certain parasites compared with those in human cells has resulted in new rationales for therapy being devel oped.
Author : Chris H. De Bruyn
Publisher : Springer Science & Business Media
ISBN 13 : 1475703902
Total Pages : 517 pages
Book Rating : 4.4/5 (757 download)
Download or read book Purine Metabolism in Man-IV written by Chris H. De Bruyn and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes, entitled "Purine Metabolism in Man IV" con tain the papers presented at the Fourth International Symposium on Human Purine and Pyrimidine Metabolism", held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo lism under normal and pathological conditions has been growing rapid ly. Apart from the more or less classical topics such as hyperuricae mia, clinical gout and urolithiasis, an increasing number of papers relating to other fields have been presented at successive meetings. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse quences for other types of cancer. At previous meetings there have been pointers implicating purine metabolism in relation to normal cardiac and skeletal muscle function. During the present meeting mych new data on both issues have been re ported which indicate clear differences in the pathways of ATP metabo lism. The widening of the field of interest is also illustrated by the recent work on infectious disease: exploitation of the differences in purine metabolic pathways in certain parasites compared with those in human cells has resulted in new rationales for therapy being devel oped.
Author : Amrik Sahota
Publisher : Springer Science & Business Media
ISBN 13 : 1461525845
Total Pages : 814 pages
Book Rating : 4.4/5 (615 download)
Download or read book Purine and Pyrimidine Metabolism in Man VIII written by Amrik Sahota and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt: These volumes record the presentations made at the VIII International Symposium on Purine and Pyrimidine Metabolism in Manheld at Indiana University, Bloomington, USA from May 22- May 27, 1994. This was a continuation of meetings held every three years with the idea of bringing clinicians and basic scientists together, which we hope results in cross-fertilization of ideas. Some of the papers presented in this volume represent oral contributions and others are from posters, but we emphasize that both are considered of equal merit. As is obvious from a perusal of the titles of the papers there has been a shift in the focus of this meeting, which reflects a general shift in the area of purine and pyrimidine metabolism. The emphasis has definitely shifted to gene structure and molecular genetics, with the beginnings we hope of gene therapy as an important branch of this area of science. Although many of the inherited diseases discussed in this text can be treated with drugs, the major thrust in the futurewill be in gene therapy, where the gene (or cDNA) will be used to treat the patient with enzyme deficiency, particularly if the patient is young. As can be seen from the Iist of authors there is a remarkable degree of international cooperation in this area across countries and continents. We thank the many participants who have attended these symposia many times, and we welcome the large group of scientists from Eastern Europe who are attending this meeting for the first time.
Author : A. Rapado
Publisher : Springer Science & Business Media
ISBN 13 : 1468485598
Total Pages : 450 pages
Book Rating : 4.4/5 (684 download)
Download or read book Purine Metabolism in Man, III written by A. Rapado and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: These volumes contain the papers which were presented at the Third International Symposium on Purine Metabolism in Man held in Madrid (Spain) in June, 1979. The previous meetings in the series were held in Tel Aviv (Israel) and in Baden (Austria) in 1973 and 1976, respectively. The proceedings were also published by Plenum. Knowledge of the pathophysiology of the purines has developed greatly since the 1950's when it was mainly related to clinical gout, and it is now relevant to many fields of Medicine and Biology. These volumes include papers reporting new work on clinical gout and urolithiasis as well as on some of the subjects which have featured prominently in the previous volumes, including: regulatory aspects of the intermediary metabolism of purines and related com pounds, enzymology, methodology, and the results of mutations which affect purine metabolism. However, there have been many new develop ments during the last three years and the scope of the communications reflects not only increasing depth of knowledge, but also a widening of the field. This publication has clinical and fundamental impli cations for internal medicine, pediatrics, urology, biochemistry, immunology, genetics, and oncology.
Author : Chris H De Bruyn
Publisher : Springer
ISBN 13 : 9781468445541
Total Pages : 578 pages
Book Rating : 4.4/5 (455 download)
Download or read book Purine Metabolism in Man-IV written by Chris H De Bruyn and published by Springer. This book was released on 2014-01-15 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Andrea Griesmacher
Publisher : Springer Science & Business Media
ISBN 13 : 9780306457784
Total Pages : 904 pages
Book Rating : 4.4/5 (577 download)
Download or read book Purine and Pyrimidine Metabolism in Man IX written by Andrea Griesmacher and published by Springer Science & Business Media. This book was released on 1998 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presented at the joint symposium held in Gmunden, Austria in June 1997 (and dedicated to the memory of Andre deVries), these 164 papers are relevant to research interests in molecular biology, biochemical pharmacology, biochemistry, developmental biology, immunology, epidemiology, and clinical applications. Topics are presented in 13 sections: gout, adenosine workshop, inborn errors of purine and pyrimidine (PP) metabolism, regulation and enzymes of PP metabolism, NMR in study of purines and energy metabolism, mutations, effects of hypoxia, free radicals, or reperfusion injury on purine, purines and signal transduction, hot research areas, immuomodulations by PP, PP in cell differentiation, the impact of PP on therapeutic strategies, and miscellaneous topics. Israel is the venue for 2000.
Author : Oded Sperling
Publisher : Springer
ISBN 13 :
Total Pages : 404 pages
Book Rating : 4.:/5 (318 download)
Download or read book Purine Metabolism in Man written by Oded Sperling and published by Springer. This book was released on 1974-03 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gout and uric acid lithiasis are known to have affected mankind for thousands of years. It is only recently, however, that great progress has been made in the understanding of the processes involved in purine metabolism and its disorders in man. The key enzymes active in the various pathways of purine synthesis and degradation have become known and their properties are the subject of intensive study. Major contributions to the knowledge of normal purine metabolism in man have derived from the study of inborn errors in patients with purine disorders, specifically complete and partial hypoxanthine-guanine phosphoribosyltransferase deficiency. Mutations of other enzymes involved in purine metabolism are being discovered. A great step forward has been made in the treatment of gout with the introduction of uricosuric drugs and more recently of the hypoxanthine analogue allopurinol, a synthetic xanthine oxidase inhibitor. Furthermore, the complex nature of the renal handling of uric acid excretion, although still posing difficult problems, appears to approach clari fication.
Author : W. L. Nyhan
Publisher : Springer Science & Business Media
ISBN 13 : 1468412485
Total Pages : 660 pages
Book Rating : 4.4/5 (684 download)
Download or read book Purine and Pyrimidine Metabolism in Man V written by W. L. Nyhan and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fifth International Symposium on Human Purine and Pyrimidine Metabolism was held in San Diego, California (U. S. A. ) in July and August of 1985. Previous meetings in this series were held in Tel Aviv (Israel), Baden (Austria), Madrid (Spain) and Maastricht (The Netherlands). The proceedings of each of these meetings were published by Plenum. The next meeting will be in Japan. This Symposium differed from those that went before in that it per mitted us to honor Dr. J. E. Seegmiller, Professor of Medicine at the University of California San Diego, for his many contributions to our understanding of purine metabolism in man. This publication is dedicated as a Festschrift to Jay. Dr. Richard W. E. Watts delivered the keynote address outlining in scholarly fashion the history of Dr. Seegmiller's accomplishments in research on purine metabolism and the great number of currently active scientists in this field who have worked with him. This address is published as the first contribution to Volume I. Dr. Dewitt Stetten, Jr. , was scheduled to be the speaker at our banquet. Unfortunate ly, he could not be with us. Dr. Seegmiller has written an appreciation of Dr. Stetten and his contributions to our field, and this has been pub lished following Dr. Watts' paper. The growth of knowledge in purine and pyrimidine metabolism continues to be exponential. The variety of subjects included in these volumes is impressive.
Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)
Download or read book Purine Metabolism in Man, Biochemistry and Pharmacology of Uric Acid Metabolism written by and published by . This book was released on 1974 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Chris H. De Bruyn
Publisher : Springer
ISBN 13 : 9780306413636
Total Pages : 0 pages
Book Rating : 4.4/5 (136 download)
Download or read book Purine Metabolism in Man-IV written by Chris H. De Bruyn and published by Springer. This book was released on 1984-01-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes, entitled "Purine Metabolism in Man IV" con tain the paper presented at the "IV. International Symposium on Human Purine and Pyrimidine Metabolism," held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo lism under normal and pathological conditions has been growing rapid ly. Apart from the more or less classical topics such as hyperuricae mia, clinical gout and urolithiasis, an increasing number of papers relating to other fields have been presented at successive meetings. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse quences for other types of cancer. At previous meetings there have been pointers implicating purine metabolism in relation to normal cardiac and skeletal muscle function. During the present meeting much new data on both issues have been re ported which indicate clear differences in the pathways of ATP metabo lism. The widening of the field of interest is also illustrated by the recent work on infectious disease: exploitation of the differences in purine metabolic pathways in certain parasites compared with those in human cells has resulted in new rationales for therapy being devel oped.
Author : R. Angus Harkness
Publisher : Springer
ISBN 13 : 9780306440922
Total Pages : 474 pages
Book Rating : 4.4/5 (49 download)
Download or read book Purine and Pyrimidine Metabolism in Man VII written by R. Angus Harkness and published by Springer. This book was released on 1991-12-31 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes record the scientific and clinical work presented at the VIIth International and 3rd European joint symposium on purine and pyrimidine metabolism in man held at the Bournemouth International Conference Centre, Bournemouth, UK, from 30th June to 5th July 1991. The series of international meetings at three yearly intervals have previously been held initially in 1973 in Israel, then Austria, Spain, the Netherlands, USA and Japan. The European society for the Study of Purine and Pyrimidine Metabolism in Man (ESSPPM) which has its own executive and some finance first met in Switzerland in 1987, then in Germany in 1989. The steady evolution of the science in this series of meetings is intellectually satisfying; the subsequent clinical progress is emotionally and economically reassuring. As befits the position of purines and pyrimidines at the centre of biochemistry, there has been steady scientific development into molecular genetics and now onto developmental controls and biochemical pharmacology. The complexities of the immune system are being unravelled but an understanding of the human brain largely eludes us. Laboratory based scientists now predominate over those who work as clinical specialists in vii rheumatology, immunology, oncology and paediatrics. However, there continue to be major clinical objectives since large sections are concerned with major causes of death like ATP depletion, cancer and now AIDS; the laboratory work is providing clinical solutions.
Author : Esther Zoref-Shani
Publisher : Springer Science & Business Media
ISBN 13 : 0306468433
Total Pages : 406 pages
Book Rating : 4.3/5 (64 download)
Download or read book Purine and Pyrimidine Metabolism in Man X written by Esther Zoref-Shani and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: th This volume contains articles presented at the X International Symposium on Purines and Pyrimidines in Man, held on May 14 19, 2000 in Tel Aviv, Israel. The first symposium in this series took place in Tel Aviv in 1973. Since then, the symposium has been held every three years in different parts of the world, including Europe, USA and Japan. The participants, in this series of symposia, are characterised by a wide interest in the various aspects of purines and pyrimidines in man, which include biochemistry, genetics, pharmacology, physiology, clinics, etc. Presentations in the symposia include clarification of metabolic pathways, characterisation of enzyme structure and kinetics and discoveries of new inborn errors of metabolism and suggestions for new therapeutic approaches for these inborn errors. In addition, development of new purine and pyrimidine derivatives for the treatment of cancer and viral diseases, and many more subjects of mutual interest were brought to the fore. With the development of therapeutic means and of new research tools, we have witnessed changes in the areas of interest. The interest in gout and uric acid urolithiasis has lessened, whereas molecular aspects, the role of purine and pyrimidine substances in neurotransmission and in purinergic signaling appear to gain greater interest. The articles, included in this volume, contain new data pertaining to the various aspects detailed above.
Author : Oded Sperling
Publisher :
ISBN 13 :
Total Pages : 846 pages
Book Rating : 4.:/5 (11 download)
Download or read book Purine Metabolism in Man: Biochemistry and Pharmacology of Uric Acid Metabolism written by Oded Sperling and published by . This book was released on 1974 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Chris H. De Bruyn
Publisher : Springer
ISBN 13 : 9780306413636
Total Pages : 0 pages
Book Rating : 4.4/5 (136 download)
Download or read book Purine Metabolism in Man-IV written by Chris H. De Bruyn and published by Springer. This book was released on 1984-01-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes, entitled "Purine Metabolism in Man IV" con tain the paper presented at the "IV. International Symposium on Human Purine and Pyrimidine Metabolism," held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo lism under normal and pathological conditions has been growing rapid ly. Apart from the more or less classical topics such as hyperuricae mia, clinical gout and urolithiasis, an increasing number of papers relating to other fields have been presented at successive meetings. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse quences for other types of cancer. At previous meetings there have been pointers implicating purine metabolism in relation to normal cardiac and skeletal muscle function. During the present meeting much new data on both issues have been re ported which indicate clear differences in the pathways of ATP metabo lism. The widening of the field of interest is also illustrated by the recent work on infectious disease: exploitation of the differences in purine metabolic pathways in certain parasites compared with those in human cells has resulted in new rationales for therapy being devel oped.
Author : Chris H. De Bruyn
Publisher : Springer
ISBN 13 : 9780306413636
Total Pages : 0 pages
Book Rating : 4.4/5 (136 download)
Download or read book Purine Metabolism in Man-IV written by Chris H. De Bruyn and published by Springer. This book was released on 1984-01-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes, entitled "Purine Metabolism in Man IV" con tain the paper presented at the "IV. International Symposium on Human Purine and Pyrimidine Metabolism," held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo lism under normal and pathological conditions has been growing rapid ly. Apart from the more or less classical topics such as hyperuricae mia, clinical gout and urolithiasis, an increasing number of papers relating to other fields have been presented at successive meetings. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse quences for other types of cancer. At previous meetings there have been pointers implicating purine metabolism in relation to normal cardiac and skeletal muscle function. During the present meeting much new data on both issues have been re ported which indicate clear differences in the pathways of ATP metabo lism. The widening of the field of interest is also illustrated by the recent work on infectious disease: exploitation of the differences in purine metabolic pathways in certain parasites compared with those in human cells has resulted in new rationales for therapy being devel oped.
