Protein Targeting, Transport, and Translocation

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Publisher : Elsevier
ISBN 13 : 0080480500
Total Pages : 441 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Protein Targeting, Transport, and Translocation by : Ross Dalbey

Download or read book Protein Targeting, Transport, and Translocation written by Ross Dalbey and published by Elsevier. This book was released on 2002-04-09 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Targeting, Transport, and Translocation presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields. - Basic principles and techniques - Targeting adn sorting sequences - Protein export in bacteria - Membrane protein integration into ER and bacterial membranes - Protein translocation across the ER - Disulfide bond formation in prokaryotes and eukaryotes - Quality control in the export pathway - Import of proteins into organelles - The secretory pathway - Vesicular transport - Spectacular color throughout

Protein Targeting, Transport & Translocation

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Publisher :
ISBN 13 : 9780122007316
Total Pages : 424 pages
Book Rating : 4.0/5 (73 download)

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Book Synopsis Protein Targeting, Transport & Translocation by : Ross E. Dalbey

Download or read book Protein Targeting, Transport & Translocation written by Ross E. Dalbey and published by . This book was released on 2002 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields. Key Features * Basic principles and techniques * Targeting adn sorting sequences * Protein export in bacteria * Membrane protein integration into ER and bacterial membranes * Protein translocation across the ER * Disulfide bond formation in prokaryotes and eukaryotes * Quality control in the export pathway * Import of proteins into organelles * The secretory pathway * Vesicular transport * Spectacular color throughout

Molecular Biology of the Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Eukaryotic Membranes and Cytoskeleton

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Publisher : Springer
ISBN 13 : 9780387740201
Total Pages : 170 pages
Book Rating : 4.7/5 (42 download)

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Book Synopsis Eukaryotic Membranes and Cytoskeleton by : Gáspár Jékely

Download or read book Eukaryotic Membranes and Cytoskeleton written by Gáspár Jékely and published by Springer. This book was released on 2007-09-14 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: The presence/absence of gene families with central roles in endomembrane and cytoskeleton dynamics in a variety of eukaryotic taxa and an understanding of eukaryote phylogeny allow the cellular machineries present in the last common ancestor of eukaryotes to be accurately reconstructed. Such a reconstruction is fundamental in order to understand eukaryotic diversification, since this is the ancestral cell from which all diversity arose. This book discusses the evolutionary origin and diversification of eukaryotic endomembranes and cytoskeleton from a cell biological and comparative genomic perspective.

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

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Publisher : CRC Press
ISBN 13 : 1420005847
Total Pages : 502 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades by : Wolfgang B. Liedtke, MD, PH.D.

Download or read book TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades written by Wolfgang B. Liedtke, MD, PH.D. and published by CRC Press. This book was released on 2006-09-29 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

Protein Secretion in Bacteria

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Publisher : John Wiley & Sons
ISBN 13 : 1683670280
Total Pages : pages
Book Rating : 4.6/5 (836 download)

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Book Synopsis Protein Secretion in Bacteria by : Maria Sandkvist

Download or read book Protein Secretion in Bacteria written by Maria Sandkvist and published by John Wiley & Sons. This book was released on 2020-07-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein transport into and across membranes is a fundamental process in bacteria that touches upon and unites many areas of microbiology, including bacterial cell physiology, adhesion and motility, nutrient scavenging, intrabacterial signaling and social behavior, toxin deployment, interbacterial antagonism and collaboration, host invasion and disruption, and immune evasion. A broad repertoire of mechanisms and macromolecular machines are required to deliver protein substrates across bacterial cell membranes for intended effects. Some machines are common to most, if not all bacteria, whereas others are specific to Gram-negative or Gram-positive species or species with unique cell envelope properties such as members of Actinobacteria and Spirochetes. Protein Secretion in Bacteria, authored and edited by an international team of experts, draws together the many distinct functions and mechanisms involved in protein translocation in one concise tome. This comprehensive book presents updated information on all aspects of bacterial protein secretion encompassing: Individual secretory systems–Sec, Tat, and T1SS through the newly discovered T9SS Mechanisms, structures, and functions of bacterial secretion systems Lipoprotein sorting pathways, outer membrane vesicles, and the sortase system Structures and roles of surface organelles, including flagella, pili, and curli Emerging technologies and translational implications Protein Secretion in Bacteria serves as both an introductory guide for students and postdocs and a ready reference for seasoned researchers whose work touches on protein export and secretion. This volume synthesizes the diversity of mechanisms of bacterial secretion across the microbial world into a digestible resource to stimulate new research, inspire continued identification and characterization of novel systems, and bring about new ways to manipulate these systems for biotechnological, preventative, and therapeutic applications.

Prokaryotic Metabolism and Physiology

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Publisher : Cambridge University Press
ISBN 13 : 1107171733
Total Pages : 509 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Prokaryotic Metabolism and Physiology by : Byung Hong Kim

Download or read book Prokaryotic Metabolism and Physiology written by Byung Hong Kim and published by Cambridge University Press. This book was released on 2019-05-16 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.

Encyclopedia of Molecular Pharmacology

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Publisher : Springer Science & Business Media
ISBN 13 : 3540389164
Total Pages : 1515 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Encyclopedia of Molecular Pharmacology by : Stefan Offermanns

Download or read book Encyclopedia of Molecular Pharmacology written by Stefan Offermanns and published by Springer Science & Business Media. This book was released on 2008-08-14 with total page 1515 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.

Bacterial Physiology and Metabolism

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Publisher : Cambridge University Press
ISBN 13 : 113946762X
Total Pages : 934 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Bacterial Physiology and Metabolism by : Byung Hong Kim

Download or read book Bacterial Physiology and Metabolism written by Byung Hong Kim and published by Cambridge University Press. This book was released on 2008-02-21 with total page 934 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent determination of genome sequences for a wide range of bacteria has made in-depth knowledge of prokaryotic metabolic function essential in order to give biochemical, physiological, and ecological meaning to the genomic information. Clearly describing the important metabolic processes that occur in prokaryotes under different conditions and in different environments, this advanced text provides an overview of the key cellular processes that determine bacterial roles in the environment, biotechnology, and human health. Prokaryotic structure is described as well as the means by which nutrients are transported into cells across membranes. Glucose metabolism through glycolysis and the TCA cycle are discussed, as well as other trophic variations found in prokaryotes, including the use of organic compounds, anaerobic fermentation, anaerobic respiratory processes, and photosynthesis. The regulation of metabolism through control of gene expression and control of the activity of enzymes is also covered, as well as survival mechanisms used under starvation conditions.

Protein Targeting to Mitochondria

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Publisher : Elsevier
ISBN 13 : 0080877001
Total Pages : 377 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Protein Targeting to Mitochondria by : F.U. Hartl

Download or read book Protein Targeting to Mitochondria written by F.U. Hartl and published by Elsevier. This book was released on 1997-02-24 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: A large number of newly-synthesized polypeptides must cross one or several intracellular membranes to reach their functional locations in the eukaryotic cell. The mechanisms of protein trafficking, in particular the post-translational targeting and membrane translocation of proteins, are of fundamental biological importance and are the focus of intensive research world-wide. For more than 15 years, mitochondria have served as the paradigm organelle system to study these processes. Although key questions, such as how precisely proteins cross a membrane, still remain to be answered, exciting progress has been made in understanding the basic pathways of protein import into mitochondria and the components involved. In addition to a fascinating richness and complexity in detail, the analysis of mitochondrial protein import has revealed mechanistic principles of general significance: Major discoveries include the demonstration of the requirement of an unfolded state for translocation and of the essential role of molecular chaperones on both sides of the membranes in maintaining a translocation-competent conformation and in protein folding after import. It is becoming clear how a polypeptide chain is "reeled" across the membrane in an ATP-dependent process by the functional cooperation of membrane proteins, presumably constituting part of a transmembrane channel, with peripheral components at the trans-side of the membrane.In this volume, eminent experts in the field take the time to review the central aspects of mitochondrial biogenesis. The logical order of the 16 chapters is determined by the sequence of steps during protein import, starting with the events taking place in the cytosol, followed by the recognition of targeting signals, the translocation of precursor proteins across the outer and inner membranes, their proteolytic processing and intramitochondrial sorting, and finally their folding and oligomeric assembly. In addition, the mechanisms involved in the export of mitochondrially encoded proteins as well as recent advances in understanding the division and inheritance of mitochondria will be discussed.

Euglena: Biochemistry, Cell and Molecular Biology

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Publisher : Springer
ISBN 13 : 3319549103
Total Pages : 304 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Euglena: Biochemistry, Cell and Molecular Biology by : Steven D. Schwartzbach

Download or read book Euglena: Biochemistry, Cell and Molecular Biology written by Steven D. Schwartzbach and published by Springer. This book was released on 2017-04-19 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This much-needed book is the first definitive volume on Euglena in twenty-fire years, offering information on its atypical biochemistry, cell and molecular biology, and potential biotechnology applications. This volume gathers together contributions from well-known experts, who in many cases played major roles in elucidating the phenomenon discussed. Presented in three parts, the first section of this comprehensive book describes novel biochemical pathways which in some instances have an atypical subcellular localization. The second section details atypical cellular mechanisms of organelle protein import, organelle nuclear genome interdependence, gene regulation and expression that provides insights into the evolutionary origins of eukaryotic cells. The final section discusses how biotechnologists have capitalized on the novel cellular and biochemical features of Euglena to produce value added products. Euglena: Biochemistry, Cell and Molecular Biology will provide essential reading for cell and molecular biologists with interests in evolution, novel biochemical pathways, organelle biogenesis and algal biotechnology. Readers will come away from this volume with a full understanding of the complexities of the Euglena as well as new realizations regarding the diversity of cellular processes yet to be discovered.

Cells: Molecules and Mechanisms

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Publisher : Axolotl Academic Publishing
ISBN 13 : 0985226110
Total Pages : 283 pages
Book Rating : 4.9/5 (852 download)

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Book Synopsis Cells: Molecules and Mechanisms by : Eric Wong

Download or read book Cells: Molecules and Mechanisms written by Eric Wong and published by Axolotl Academic Publishing. This book was released on 2009 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology."--Open Textbook Library.

Intracellular Trafficking of Proteins

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Author :
Publisher : CUP Archive
ISBN 13 : 9780521361200
Total Pages : 798 pages
Book Rating : 4.3/5 (612 download)

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Book Synopsis Intracellular Trafficking of Proteins by : Clifford J. Steer

Download or read book Intracellular Trafficking of Proteins written by Clifford J. Steer and published by CUP Archive. This book was released on 1991-07-18 with total page 798 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Liver

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Publisher : John Wiley & Sons
ISBN 13 : 1119436826
Total Pages : 1156 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis The Liver by : Irwin M. Arias

Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Trafficking Inside Cells

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Publisher : Springer Science & Business Media
ISBN 13 : 038793877X
Total Pages : 459 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis Trafficking Inside Cells by : Nava Segev

Download or read book Trafficking Inside Cells written by Nava Segev and published by Springer Science & Business Media. This book was released on 2010-05-30 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.

Plant Mitochondria

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Author :
Publisher : Humana
ISBN 13 : 9781493926381
Total Pages : 0 pages
Book Rating : 4.9/5 (263 download)

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Book Synopsis Plant Mitochondria by : James Whelan

Download or read book Plant Mitochondria written by James Whelan and published by Humana. This book was released on 2015-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters compiled in this detailed collection outline a number of methods used to study plant mitochondria today, starting from the isolation of mitochondria to detailed analyses of RNA, protein and enzymatic activities. Given that the ability to uncover mitochondria’s unique features is underpinned by current methodology, this book explores the subject from morphology to detailed molecular mechanisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Plant Mitochondria: Methods and Protocols serves as a vital resource to beginners in the field as well as to expert researchers who find themselves being pulled into the field of mitochondrial research as it links to so many important aspects of plant cell biology.

Heat Shock Proteins in Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 1402064012
Total Pages : 399 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Heat Shock Proteins in Cancer by : Stuart K. Calderwood

Download or read book Heat Shock Proteins in Cancer written by Stuart K. Calderwood and published by Springer Science & Business Media. This book was released on 2007-09-09 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.