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Proteases New Perspectives

Author : Vito Turk
Publisher : Birkhäuser
ISBN 13 : 303488737X
Total Pages : 238 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Proteases New Perspectives by : Vito Turk

Download or read book Proteases New Perspectives written by Vito Turk and published by Birkhäuser. This book was released on 2012-12-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an account of the recent advances in our understanding of the role of proteases under physiological and pathological conditions. It reviews the contributions that have been made in the fields of biochemistry, molecular biology, medicine, agriculture and ecology. In addition there is an account of the growing number of practical applications in biotechnology, reflecting the fact that peptidases are major targets for medical and agricultural purposes. The book shows how the numerous protease structures are essential for drug design. The contributions place special emphasis on cysteine, aspartic and metalloproteases and their role in physiological and certain pathological states. Another focus is the classification and nomenclature of peptidases and a review of those proteases currently under the most intensive investigation. The book provides an informative introduction for teachers and newcomers to the field, such as graduate students, while providing a valuable source of material and ideas for the academic and industrial researcher in areas including biochemistry, medicine, agriculture and biotechnology.

Proteases New Perspectives

Author : Vito Turk
Publisher :
ISBN 13 : 9783034887380
Total Pages : 252 pages
Book Rating : 4.8/5 (873 download)

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Book Synopsis Proteases New Perspectives by : Vito Turk

Download or read book Proteases New Perspectives written by Vito Turk and published by . This book was released on 1999-12-01 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an account of the recent advances in our understanding of the role of proteases under physiological and pathological conditions. It reviews the contributions that have been made in the fields of biochemistry, molecular biology, medicine, agriculture and ecology. In addition there is an account of the growing number of practical applications in biotechnology, reflecting the fact that peptidases are major targets for medical and agricultural purposes. The book shows how the numerous protease structures are essential for drug design. The contributions place special emphasis on cysteine, aspartic and metalloproteases and their role in physiological and certain pathological states. Another focus is the classification and nomenclature of peptidases and a review of those proteases currently under the most intensive investigation. The book provides an informative introduction for teachers and newcomers to the field, such as graduate students, while providing a valuable source of material and ideas for the academic and industrial researcher in areas including biochemistry, medicine, agriculture and biotechnology.

New Perspectives in Plant Protection

Author : Ali R. Bandani
Publisher : BoD – Books on Demand
ISBN 13 : 953510490X
Total Pages : 262 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis New Perspectives in Plant Protection by : Ali R. Bandani

Download or read book New Perspectives in Plant Protection written by Ali R. Bandani and published by BoD – Books on Demand. This book was released on 2012-04-11 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crop losses by pests (insects, diseases and weeds) are as old as plant themselves but as agriculture are intensified and cropping patterns including the cultivation of high yielding varieties and hybrids are changing over time the impact of the pests becoming increasingly important. Approximately less than 1000 insect species (roughly 600-800 species), 1500 -2000 plant species, numerous fungal, bacterial and nematode species as well as viruses are considered serious pests in agriculture. If these pests were not properly controlled, crop yields and their quality would drop, considerably. In addition production costs as well as food and fiber prices are increased. The current book is going to put Plant Protection approaches in perspective.

Aspartic Acid Proteases as Therapeutic Targets

Author : Arun K. Ghosh
Publisher : John Wiley & Sons
ISBN 13 : 3527641629
Total Pages : 616 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Aspartic Acid Proteases as Therapeutic Targets by : Arun K. Ghosh

Download or read book Aspartic Acid Proteases as Therapeutic Targets written by Arun K. Ghosh and published by John Wiley & Sons. This book was released on 2011-08-04 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular structure and inhibition. Parts two to five present various case studies of successful protease inhibitor drug design and development, as well as current and potential uses of such inhibitors in pharmaceutical medicine, covering the major therapeutic targets HIV-1 protease, renin, beta-secretase, gamma-secretase,plasmepsins and fungal proteases. A ready reference aimed primarily at professionals in the pharmaceutical industry, as well as for anyone studying proteases and their function.

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

New Perspectives in Prostate Cancer

Author : Arie Belldegrun
Publisher : CRC Press
ISBN 13 : 9780203091968
Total Pages : 472 pages
Book Rating : 4.0/5 (919 download)

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Book Synopsis New Perspectives in Prostate Cancer by : Arie Belldegrun

Download or read book New Perspectives in Prostate Cancer written by Arie Belldegrun and published by CRC Press. This book was released on 1998-03-01 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: A summary of the highlights of the Second International Forum on Prostate Cancer, held in Cambridge in 1998. The contributors include scientists, epidemiologists and clinicians who provide both a North American and a European view of treatment. The patient's perspective is also considered.

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

Author : Wolfgang B. Liedtke, MD, PH.D.
Publisher : CRC Press
ISBN 13 : 1420005847
Total Pages : 502 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades by : Wolfgang B. Liedtke, MD, PH.D.

Download or read book TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades written by Wolfgang B. Liedtke, MD, PH.D. and published by CRC Press. This book was released on 2006-09-29 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

Handbook of Proteolytic Enzymes, Volume 1

Author : Alan J. Barrett
Publisher : Elsevier
ISBN 13 : 0080984150
Total Pages : 1182 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Handbook of Proteolytic Enzymes, Volume 1 by : Alan J. Barrett

Download or read book Handbook of Proteolytic Enzymes, Volume 1 written by Alan J. Barrett and published by Elsevier. This book was released on 2012-12-02 with total page 1182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Proteolytic Enzymes, Second Edition, Volume 1: Aspartic and Metallo Peptidases is a compilation of numerous progressive research studies on proteolytic enzymes. This edition is organized into two main sections encompassing 328 chapters. This handbook is organized around a system for the classification of peptidases, which is a hierarchical one built on the concepts of catalytic type, clan, family and peptidase. The concept of catalytic type of a peptidase depends upon the chemical nature of the groups responsible for catalysis. The recognized catalytic types are aspartic, cysteine, metallo, serine, threonine, and the unclassified enzymes, while clans and families are groups of homologous peptidases. Homology at the level of a family of peptidases is shown by statistically significant relationship in amino acid sequence to a representative member called the type example, or to another member of the family that has already been shown to be related to the type example. Each chapter discusses the history, activity, specificity, structural chemistry, preparation, and biological aspects of the enzyme. This book will prove useful to enzyme chemists and researchers.

Proteases in Apoptosis: Pathways, Protocols and Translational Advances

Author : Kakoli Bose
Publisher : Springer
ISBN 13 : 3319194976
Total Pages : 245 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Proteases in Apoptosis: Pathways, Protocols and Translational Advances by : Kakoli Bose

Download or read book Proteases in Apoptosis: Pathways, Protocols and Translational Advances written by Kakoli Bose and published by Springer. This book was released on 2015-08-06 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the proteases involved in programmed cell death. It presents a focused yet extensive discussion on proteolytic enzymes such as caspases, HtrAs, granzymes, calpains and cathepsins as well as laboratory protocols related to enzymology and apoptosis. Mouse model systems and non-invasive imaging techniques in apoptosis-related diseases such as cancer and neurodegeneration are also covered in this book. While slowly unravelling the complexities of apoptosis in chapter one, the next three chapters individually elaborate on different classes of proteases that play key roles in the initiation, progression and execution of programmed cell death. The last two chapters complete this discussion by describing different laboratory methodologies and therapeutic advances involving apoptotic proteases. Protocols portraying in vitro and ex vivo colorimetric and fluorescence-based enzyme kinetic studies as well as cell death assays are explained in the fifth chapter. Preclinical in vivo models and non-invasive imaging in apoptosis to understand the complexities of disease progression and their contribution toward therapeutics is recounted in the last chapter. The book spans topics related to both fundamental and applied biology. It would therefore be equally appealing and informative to scientists working in the field of apoptosis and those who are investigating mechanisms of proteases and enzymes in general. The protocols would certainly benefit both graduate and undergraduate students working in the related fields and provide useful leads for drug design to translational biologists involved in neurodegeneration and cancer research.

Bioactive Molecules in Food

Author : Jean-Michel Mérillon
Publisher : Springer Nature
ISBN 13 : 3319780301
Total Pages : 2353 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Bioactive Molecules in Food by : Jean-Michel Mérillon

Download or read book Bioactive Molecules in Food written by Jean-Michel Mérillon and published by Springer Nature. This book was released on 2019-01-25 with total page 2353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work provides comprehensive information about the bioactive molecules presented in our daily food and their effect on the physical and mental state of our body. Although the concept of functional food is new, the consumption of selected food to attain a specific effect existed already in ancient civilizations, namely of China and India. Consumers are now more attentive to food quality, safety and health benefits, and the food industry is led to develop processed- and packaged-food, particularly in terms of calories, quality, nutritional value and bioactive molecules. This book covers the entire range of bioactive molecules presented in daily food, such as carbohydrates, proteins, lipids, isoflavonoids, carotenoids, vitamin C, polyphenols, bioactive molecules presented in wine, beer and cider. Concepts like French paradox, Mediterranean diet, healthy diet of eating fruits and vegetables, vegan and vegetarian diet, functional foods are described with suitable case studies. Readers will also discover a very timely compilation of methods for bioactive molecules analysis. Written by highly renowned scientists of the field, this reference work appeals to a wide readership, from graduate students, scholars, researchers in the field of botany, agriculture, pharmacy, biotechnology and food industry to those involved in manufacturing, processing and marketing of value-added food products.

Plant Proteases

Author : Mercedes Diaz-Mendoza
Publisher : Frontiers Media SA
ISBN 13 : 2889633993
Total Pages : 157 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Plant Proteases by : Mercedes Diaz-Mendoza

Download or read book Plant Proteases written by Mercedes Diaz-Mendoza and published by Frontiers Media SA. This book was released on 2020-01-24 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant proteases are involved in most aspects of plant physiology and development, playing key roles in the generation of signaling molecules and as regulators of essential cellular processes such as cell division and metabolism. They take part in important pathways like protein turnover by the degradation of misfolded proteins and the ubiquitin-proteasome pathway, and they are responsible for post-translational modifications of proteins by proteolysis at highly specific sites. Proteases are also implicated in a great variety of environmentally controlled processes, including mobilization of storage proteins during seed germination, development of seedlings, senescence, programmed cell death and defense mechanisms against pests and pathogens. However, in spite of their importance, little is known about the functions and mode of actions of specific plant proteases. This Research Topic collects contributions covering diverse aspects of plant proteases research.

HIV/AIDS: New Insights for the Healthcare Professional: 2012 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 146496971X
Total Pages : 1894 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis HIV/AIDS: New Insights for the Healthcare Professional: 2012 Edition by :

Download or read book HIV/AIDS: New Insights for the Healthcare Professional: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 1894 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV/AIDS: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about HIV/AIDS. The editors have built HIV/AIDS: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about HIV/AIDS in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of HIV/AIDS: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Proteases in Human Diseases

Author : Sajal Chakraborti
Publisher : Springer
ISBN 13 : 9811031622
Total Pages : 513 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Proteases in Human Diseases by : Sajal Chakraborti

Download or read book Proteases in Human Diseases written by Sajal Chakraborti and published by Springer. This book was released on 2017-07-13 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book bridges the gap between fundamental research and biomedical and pharmacological applications on proteases. It represents a comprehensive overview of the multifaceted field of proteases in cellular environment and highlights the recently elucidated functions of complex proteolytic systems in different diseases. Several established investigators have elucidated the crucial role of proteases in biological processes, including how proteolytic function and regulation can be combined to develop new strategies of therapeutic interventions. Proteases form one of the largest and most diverse families of enzymes known. It is now clear that proteases are involved in every aspect of life functions of an organism. Under physiological conditions, proteases are regulated by their endogenous inhibitors; however, when the activity of proteases is not regulated appropriately, disease processes can result in. So, there is absolute need for a stringent control of proteolytic activities in cells and tissues. Dysregulation of proteases may cause derangement of cellular signalling network resulting in different pathophysiological conditions such as vascular remodelling, atherosclerotic plaque progression, ulcer and rheumatoid arthritis, Alzheimer disease, cancer metastasis, tumor progression and inflammation. Additionally, many infective microorganisms require proteases for replication or use proteases as virulence factors, which have facilitated the development of protease-targeted therapies for a variety of parasitic diseases.

Antiphospholipid Syndrome: New Insights for the Healthcare Professional: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 146490894X
Total Pages : 42 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Antiphospholipid Syndrome: New Insights for the Healthcare Professional: 2011 Edition by :

Download or read book Antiphospholipid Syndrome: New Insights for the Healthcare Professional: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antiphospholipid Syndrome: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Antiphospholipid Syndrome in a compact format. The editors have built Antiphospholipid Syndrome: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Antiphospholipid Syndrome in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Antiphospholipid Syndrome: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Insect Molecular Biology and Biochemistry

Author : Lawrence I. Gilbert
Publisher : Academic Press
ISBN 13 : 0123847486
Total Pages : 575 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Insect Molecular Biology and Biochemistry by : Lawrence I. Gilbert

Download or read book Insect Molecular Biology and Biochemistry written by Lawrence I. Gilbert and published by Academic Press. This book was released on 2011-08-16 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of the extensive seven-volume work Comprehensive Molecular Insect Science provided a complete reference encompassing important developments and achievements in modern insect science. One of the most swiftly moving areas in entomological and comparative research is molecular biology, and this volume, Insect Molecular Biology and Biochemistry, is designed for those who desire a comprehensive yet concise work on important aspects of this topic. This volume contains ten fully revised or rewritten chapters from the original series as well as five completely new chapters on topics such as insect immunology, insect genomics, RNAi, and molecular biology of circadian rhythms and circadian behavior. The topics included are key to an understanding of insect development, with emphasis on the cuticle, digestive properties, and the transport of lipids; extensive and integrated chapters on cytochrome P450s; and the role of transposable elements in the developmental processes as well as programmed cell death. This volume will be of great value to senior investigators, graduate students, post-doctoral fellows and advanced undergraduate research students. It can also be used as a reference for graduate courses and seminars on the topic. Chapters will also be valuable to the applied biologist or entomologist, providing the requisite understanding necessary for probing the more applied research areas related to insect control. Topics specially selected by the editor-in-chief of the original major reference work Fully revised and new contributions bring together the latest research in the rapidly moving fields of insect molecular biology and insect biochemistry, including coverage of development, physiology, immunity and proteomics Full-color provides readers with clear, useful illustrations to highlight important research findings

Proteases in Physiology and Pathology

Author : Sajal Chakraborti
Publisher : Springer
ISBN 13 : 9811025134
Total Pages : 619 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Proteases in Physiology and Pathology by : Sajal Chakraborti

Download or read book Proteases in Physiology and Pathology written by Sajal Chakraborti and published by Springer. This book was released on 2017-09-14 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a multidisciplinary approach, this book describes the biochemical mechanisms associated with dysregulation of proteases and the resulting pathophysiological consequences. It highlights the role and regulation of different types of proteases as well as their synthetic and endogenous inhibitors. The role of proteases was initially thought to be limited to general metabolic digestion. However, we now know that the role of protein breakdown is much more complex, and proteases have multiple functions: they are coupled to turnover and can affect protein composition, function and synthesis. In addition to eliminating abnormal proteins, breakdown has many modulatory functions, including activating and inactivating enzymes, modulating membrane function, altering receptor channel properties, affecting transcription and cell cycles and forming active peptides. The ubiquity of proteases in nature makes them an important target for drug development. This in-depth, comprehensive is a valuable resource for researchers involved in identifying new targets for drug development. With its multidisciplinary scope, it bridges the gap between fundamental and translational research in the biomedical and pharmaceutical industries, making it thought-provoking reading for scientists in the field.

Thrombosis: New Insights for the Healthcare Professional: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464900973
Total Pages : 229 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Thrombosis: New Insights for the Healthcare Professional: 2011 Edition by :

Download or read book Thrombosis: New Insights for the Healthcare Professional: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thrombosis: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Embolism and Thrombosis. The editors have built Thrombosis: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Embolism and Thrombosis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Thrombosis: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.