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Author : Abraham Stolman
Publisher :
ISBN 13 : 9781483199887
Total Pages : 413 pages
Book Rating : 4.1/5 (998 download)
Download or read book Progress in Chemical Toxicology written by Abraham Stolman and published by . This book was released on 1967 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Progress in chemical toxicology written by and published by . This book was released on 1963 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Abraham Stolman
Publisher : Elsevier
ISBN 13 : 1483224910
Total Pages : 431 pages
Book Rating : 4.4/5 (832 download)
Download or read book Progress in Chemical Toxicology written by Abraham Stolman and published by Elsevier. This book was released on 2013-10-22 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Chemical Toxicology, Volume 3 explores the developments in methods and instrumentation for toxicological analyses. This book is composed of eight chapters, and begins with a description of the pharmacologic and physiologic effects of aliphatic alcohols. The succeeding chapter deals with the methods of analysis of various volatile poisons, such as halogenated aliphatic compounds, aromatic hydrocarbons, and acid compounds. A chapter focuses on the methods of determination and classic procedures for carbon monoxide analysis in breath and blood. These topics are followed by discussions on the development of spectrochemical methods chemical and radiochemical methods of determination of radionuclides in human bones and tissues; and the toxic effects of combined drug action. The last chapter examines the poison residue occurrence in human tissues. This book is of great value to toxicologists and public health workers and researchers.
Author : Abraham Stolman
Publisher : Elsevier
ISBN 13 : 1483219224
Total Pages : 449 pages
Book Rating : 4.4/5 (832 download)
Download or read book Progress in Chemical Toxicology written by Abraham Stolman and published by Elsevier. This book was released on 2013-10-22 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Chemical Toxicology, Volume 1 covers the developments in toxicology, including the usefulness of the developed techniques and methods with necessary modifications for toxicological studies. The book describes the isolation and separation techniques for the identification of poisons; the application of gas chromatograph to toxicology; and the pharmacological and toxicological effects aliphatic alcohols. The text also discusses the isolation, purification, identication, and the toxicology of acidic and neutral poisons, ataraxics and nonbarbiturate sedatives. The determination of antiarthritics, antihistamines, and thymoleptics; the physicochemical properties for the identification of narcotics and related bases; and the toxicity of air pollutants are also considered. The book further tackles the analytical methods for air pollutants; the occurrence, symptoms, and treatment of mushroom poisoning; and the toxic components of poisonous seeds and fruits poisonous seeds and fruits. Toxicologists, chemists, and scientists in forensic science laboratories will find the text invaluable.
Author : Abraham Stolman
Publisher : Elsevier
ISBN 13 : 1483219240
Total Pages : 406 pages
Book Rating : 4.4/5 (832 download)
Download or read book Progress in Chemical Toxicology written by Abraham Stolman and published by Elsevier. This book was released on 2013-10-22 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Chemical Toxicology, Volume 5 covers topics on the improved isolation and detection procedures and quantitation methods for volatile poisons, stimulants, hallucinogenic drugs, and marihuana. The book discusses the absorption, distribution, and excretion of drugs and poisons and their metabolites; the system for the toxicological analysis of drugs in biological specimens; and the isolation and analysis of phenothiazines. The text also describes the use of fluorescence in toxicology and the toxicology of new synthetic organic polymers used in containers for food, pharmaceutical compounds, and drinkable water. Some microcrystal tests for drugs and advances in polarography as applied to toxicological analysis are also considered. Biochemists, toxicologists, and scientists involved in the study of narcotics will find the book invaluable.
Author : Abraham Stolman
Publisher : Elsevier
ISBN 13 : 1483219232
Total Pages : 441 pages
Book Rating : 4.4/5 (832 download)
Download or read book Progress in Chemical Toxicology written by Abraham Stolman and published by Elsevier. This book was released on 2013-10-22 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Chemical Toxicology, Volume 4 covers the capabilities of paper and thin-layer chromatography to separate closely resembling drugs and some of their metabolites. The book discusses the use of interfering compounds and artifacts in the identification of drugs in autopsy material; paper and thin layer chromatographic techniques for separation and identification of barbiturates and related hypnotics; and the forensic chemical detection of digitalis glycosides. The text also describes the applications of atomic absorption spectrometry to trace metal analyses of toxicological materials; and the toxicology of insecticides, rodenticides, herbicides, and phytopharmaceutical compounds. The combined action of drugs with toxicological implications is also considered. Chemists, toxicologists, biochemists, and forensics will find the book invaluable.
Author : Abraham Stolman
Publisher : Elsevier
ISBN 13 : 1483224902
Total Pages : 427 pages
Book Rating : 4.4/5 (832 download)
Download or read book Progress in Chemical Toxicology written by Abraham Stolman and published by Elsevier. This book was released on 2013-10-22 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Chemical Toxicology, Volume 2 reviews significant developments in chemical toxicology, with particular reference to the mode of absorption, distribution, excretion, and metabolism of drugs and poisons in both humans and animals. Some of the techniques for the rapid infrared analysis and identification of gases in human breath are also discussed, along with rapid drug analysis by ion-exchange paper chromatography and ionophoresis. Comprised of six chapters, this volume first deals with the absorption, distribution, and excretion of poisons and their metabolites, including drugs extractable by organic solvents from aqueous acid and alkaline solutions. Subsequent chapters focus on the use of rapid infrared techniques in the detection of volatile organic compounds and toxic gases in humans; rapid methods of toxicological analysis by ion-exchange paper chromatography and ionophoresis; sample preparation and techniques for concentration of metal poisons for increased sensitivity of spectrographic analysis; and application of thin layer chromatography in toxicology. An approach to the analysis of biological specimens for basic drugs is also described. This book will be of interest to chemists and toxicologists.
Author : Gerhard Zbinden
Publisher : Springer-Verlag
ISBN 13 : 3642662927
Total Pages : 124 pages
Book Rating : 4.6/5 (426 download)
Download or read book Progress in Toxicology written by Gerhard Zbinden and published by Springer-Verlag. This book was released on 2013-03-07 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE STATE OF THE ART The recent seventies have not been good times for toxicologists. Public confidence in us is shaken, mostly as a consequence of an unhappy sequence of spectacular failures: we have been surprised by a tragic transplacental carcinogenic effect of diethylstilbestrol, an old and widely prescribed synthetic estrogen. We are confronted with a small epidemic of an unusual liver tumor, angiosarcoma, induced by a simple chemical, vinylchloride, whose insiduous toxic potential we failed to "recognize for years. Our clinical colleagues had to tell us about the ulcerogenic effect of as simple a substance as potassium chloride. We also just learned of an unusual toxic reaction, pseudolupus, developing in people taking a popular fixed-combination drug, venocuran~ Admit tedly, we could not have predicted this syndrome, even if we had con sidered the possibility. We are still unable (to continue this self-flagellation) to explain the relationship between the appetite suppressant arninorex and the sud denly increased occurrence of a lung disease posing as primary pulmonary hypertension. And worse yet, we have no way to evaluate a new deriva tive of this class, and to predict whether or not it, too, will produce the deadly condition. We still, to my knowledge, have no plausible ex planation why and how thalidomide caused phocomelia. Of course, we do diligently a set of teratological experiments with each new drug; we follow a protocol which has the blessing of all governmental regulatory agencies.
Author : Ernest Hodgson
Publisher : Academic Press
ISBN 13 : 0124158137
Total Pages : 452 pages
Book Rating : 4.1/5 (241 download)
Download or read book Toxicology and Human Environments written by Ernest Hodgson and published by Academic Press. This book was released on 2012-09-28 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental toxicology is generally held to be the study of the potential of constituents of outdoor environments to impact either human health or the biological structure of the ecosystems involved. This volume is a first attempt to integrate toxicological studies of all of the many human environments, both indoor and outdoor, and their complex interrelationships. Included are considerations of natural environments, the agroecosystem, occupational, urban and domestic environments as well as the environment associated with Superfund sites and military deployments. The primary emphasis is on public health, including the potential health effects of toxicants found in different environments, the bioprocessing of such toxicants in humans and surrogate animals and the principles of risk analysis. Approaches the toxicology of human environments in a new and unique way, stressing the complex interrelationships of all human environments and the implication for human and environmental health Each chapter is written by an acknowledged expert and is addressed to those interested in the broader implications of the environmental modifications that are always associated with the activities of humans living and working in them
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309151732
Total Pages : 217 pages
Book Rating : 4.3/5 (91 download)
Download or read book Toxicity Testing in the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2007-11-05 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
Author : John H Duffus
Publisher : Royal Society of Chemistry
ISBN 13 : 1847559751
Total Pages : 189 pages
Book Rating : 4.8/5 (475 download)
Download or read book Concepts in Toxicology written by John H Duffus and published by Royal Society of Chemistry. This book was released on 2009-10-01 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology has never been more important. Advances in chemistry and technology offering improvements in the quality of human life become ever more rapid, bringing with them the potential for new toxicity hazards. This has led to legislation requiring toxicity testing and risk assessment for all chemicals and their uses. The new REACH (Risk Evaluation and Authorization of Chemicals) Regulation has profound economic consequences because, without official authorization, a chemical cannot be marketed. This book explains, in depth, the ideas underlying current advances in toxicology and its application in regulating and ensuring the safe use of chemicals. Sometimes old ideas have become assumptions that have become embedded in related laws and regulation, even though the thinking of toxicologists has moved on in line with developments in science. This leads to confusion in public understanding that the book should dispel. There are also fundamental ideas in toxicology that are not well understood concerning the concepts of hazard and risk and even about what constitutes a chemical. For many people the word 'chemical' describes manmade substances only. In fact, it is correctly applied to all substances that exist, from pure elements to the most complex biological molecules in food and medicines. This is further complicated by the complex distinction between the descriptors, 'toxic' and 'nontoxic'. Developments in epigenetics are revolutionizing our understanding of mutagenicity and carcinogenicity. Improved understanding of apoptosis and necrosis leads to improved interpretation of potentially toxic effects at the cellular level. The recently defined term 'chemical speciation' is driving more targeted research on the toxicity of inorganic chemicals. This book explains the concepts implied by key toxicological terms using diagrams to illustrate the relationships between them. It is an essential aid to understanding the new demands from regulators of risk assessment and to the implementation of appropriate risk management.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309120462
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)
Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.
Author :
Publisher : Elsevier Science
ISBN 13 : 9780444528421
Total Pages : 200 pages
Book Rating : 4.5/5 (284 download)
Download or read book Advances in Molecular Toxicology written by and published by Elsevier Science. This book was released on 2006-12-23 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field. Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of both progress on the molecular level and on advances in technological approaches employed. * Cutting edge reviews by leading workers in the discipline. * In depth dissection of molecular aspects of interest to a broad range of scientists, physisicans and any student in the allied disciplines. * Leading edge applications of technological innovations in the chemistry, biochemistry and molecular medicine.
Author : Alexandra Maertens
Publisher : Royal Society of Chemistry
ISBN 13 : 1839164409
Total Pages : 307 pages
Book Rating : 4.8/5 (391 download)
Download or read book Green Toxicology written by Alexandra Maertens and published by Royal Society of Chemistry. This book was released on 2022-02-01 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green toxicology is an integral part of green chemistry. One of the key goals of green chemistry is to design less toxic chemicals. Therefore, an understanding of toxicology and hazard assessment is important for any chemist working in green chemistry, but toxicology is rarely part of most chemists' education. As a consequence, chemists lack the toxicological lens necessary to view chemicals in order to design safer substitutions. This book seeks to fill that gap and demonstrate how a basic understanding of toxicology, as well as the tools of in silico and in vitro toxicology, can be an integral part of green chemistry. R&D chemists, product stewards, and toxicologists who work in the field of sustainability, can all benefit from integrating green toxicology principles into their work. Topics include in silico tools for hazard assessment, toxicity testing, and lifecycle considerations, this book aims to act as a bridge between green toxicologists and green chemists.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309112982
Total Pages : 300 pages
Book Rating : 4.3/5 (91 download)
Download or read book Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2007-12-19 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.
Author :
Publisher : Elsevier
ISBN 13 : 9780444561978
Total Pages : 0 pages
Book Rating : 4.5/5 (619 download)
Download or read book Advances in Molecular Toxicology written by and published by Elsevier. This book was released on 2010-07-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field. Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of both progress on the molecular level and on advances in technological approaches employed. Cutting-edge reviews by leading workers in the discipline In-depth dissection of molecular aspects of interest to a broad range of scientists, physicians and any student in the allied disciplines Leading edge applications of technological innovations in chemistry, biochemistry and molecular medicine
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309184029
Total Pages : 235 pages
Book Rating : 4.3/5 (91 download)
Download or read book Impact of Advances in Computing and Communications Technologies on Chemical Science and Technology written by National Research Council and published by National Academies Press. This book was released on 1999-08-31 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemical Sciences Roundtable provides a forum for discussing chemically related issues affecting government, industry and government. The goal is to strengthen the chemical sciences by foster communication among all the important stakeholders. At a recent Roundtable meeting, information technology was identified as an issue of increasing importance to all sectors of the chemical enterprise. This book is the result of a workshop convened to explore this topic.
