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Program Review Report Of The Board Of Scientific Counselors Endocrine Disrupting Chemicals Edc Research Program
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Book Synopsis Program Review Report of the Board of Scientific Counselors Endocrine Disrupting Chemicals (EDC) Research Program by :
Download or read book Program Review Report of the Board of Scientific Counselors Endocrine Disrupting Chemicals (EDC) Research Program written by and published by . This book was released on 2005 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Program review report of the Board of Scientific Counselors endocrine disrupting chemicals (EDC) research program by :
Download or read book Program review report of the Board of Scientific Counselors endocrine disrupting chemicals (EDC) research program written by and published by DIANE Publishing. This book was released on with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Environmental Health Perspectives by :
Download or read book Environmental Health Perspectives written by and published by . This book was released on 2006-08 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Program Review Report of the Board of Scientific Counselors Human Health Research Program by :
Download or read book Program Review Report of the Board of Scientific Counselors Human Health Research Program written by and published by . This book was released on 2005 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Interior, Environment, and Related Agencies Appropriations for 2011, Part 3, 111-2 Hearings by :
Download or read book Interior, Environment, and Related Agencies Appropriations for 2011, Part 3, 111-2 Hearings written by and published by . This book was released on 2010 with total page 1448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Review of the Environmental Protection Agency's State-of-the-Science Evaluation of Nonmonotonic Dose-Response Relationships as they Apply to Endocrine Disruptors by : National Research Council
Download or read book Review of the Environmental Protection Agency's State-of-the-Science Evaluation of Nonmonotonic Dose-Response Relationships as they Apply to Endocrine Disruptors written by National Research Council and published by National Academies Press. This book was released on 2014-05-27 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Potential health effects from chemicals that disrupt endocrine function pose an environmental health concern because of their ability to interfere with normal hormone function in human and wildlife populations. The endocrine system regulates biological processes throughout the body and is sensitive to small changes in hormone concentrations. Endocrine-disruptor research has focused primarily on chemicals that affect three hormone pathways that play important roles in reproduction and development - the estrogen, androgen, and thyroid hormone pathways. Some of this research has identified dose-response relationships that have nonmonotonic curves. Nonmonotonic dose-response curves (NMDRs) are of concern because they do not follow the usual assumption made in toxicology that as dose decreases the response also decreases. The existence of NMDRs has been a controversial topic for decades, and there has been considerable debate about their implications for how chemicals are tested and for how risks from such chemicals are assessed. Toxicity tests are designed to identify hazards and to characterize dose-response relationships, so tests are aimed at finding a (high) dose that elicits a response, and dose-response is explored by testing lower doses spaced to identify statistically a no- or lowest-observed-adverse-effect level. The concern for NMDRs is that such studies, as currently designed, might not detect the inflection of the dose-response curve if only a few doses are tested or if the change in inflection occurs below the range of doses tested. Another concern is that some NMDRs are found for biological effects that are not usually evaluated in toxicity tests. If current testing strategies are inadequate to account for NMDRs, changes to risk assessment practices might be necessary. To help address these issues, the U.S. Environmental Protection Agency (EPA) developed a draft State-of-the-Science Evaluation: Nonmonotonic Dose Responses as they Apply to Estrogen, Androgen, and Thyroid Pathways and EPA Testing and Assessment Procedures. EPA asked the National Research Council to conduct an independent review of this evaluation to ensure that it is scientifically sound and of high quality. Review of Environmental Protection Agency's State-of-the-Science Evaluation of Nonmonotonic Dose-Response as they Apply to Endocrine Disrupters evaluates whether EPA's evaluation presents a scientifically sound and high-quality analysis of the literature on NMDRs. This report reviews how well the EPA evaluation described how the assessment was performed, whether consistent methods and criteria were applied in the analysis of different evidence streams, and whether appropriate methods were applied to evaluating the evidence. The report makes recommendations to improve EPA's process and strengthen the evaluation.
Author :United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Energy and Environment Publisher : ISBN 13 : Total Pages :192 pages Book Rating :4.:/5 (319 download)
Book Synopsis Endocrine-disrupting Chemicals in Drinking Water by : United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Energy and Environment
Download or read book Endocrine-disrupting Chemicals in Drinking Water written by United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Energy and Environment and published by . This book was released on 2012 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Environment Reporter written by and published by . This book was released on 2004 with total page 1468 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Integrity in Scientific Research by : National Research Council
Download or read book Integrity in Scientific Research written by National Research Council and published by National Academies Press. This book was released on 2002-10-02 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Many people say that it is the intellect which makes a great scientist. They are wrong: it is character."-Albert Einstein Integrity in Scientific Research attempts to define and describe those elements that encourage individuals involved with scientific research to act with integrity. Recognizing the inconsistency of human behavior, it stresses the important role that research institutions play in providing an integrity-rich environment, citing the need for institutions to provide staff with training and education, policies and procedures, and tools and support systems. It identifies practices that characterize integrity in such areas as peer review and research on human subjects and weighs the strengths and limitations of self-evaluation efforts by these institutions. In addition, it details an approach to promoting integrity during the education of researchers, including how to develop an effective curriculum. Providing a framework for research and educational institutions, this important book will be essential for anyone concerned about ethics in the scientific community.
Book Synopsis Hormonally Active Agents in the Environment by : National Research Council
Download or read book Hormonally Active Agents in the Environment written by National Research Council and published by National Academies Press. This book was released on 2000-01-03 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.
Author :Agency for Healthcare Research and Quality/AHRQ Publisher :Government Printing Office ISBN 13 :1587634333 Total Pages :396 pages Book Rating :4.5/5 (876 download)
Book Synopsis Registries for Evaluating Patient Outcomes by : Agency for Healthcare Research and Quality/AHRQ
Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.
Book Synopsis National Toxicology Program Annual Report for Fiscal Year ... by : National Toxicology Program (U.S.)
Download or read book National Toxicology Program Annual Report for Fiscal Year ... written by National Toxicology Program (U.S.) and published by . This book was released on 1992 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Phthalates and Cumulative Risk Assessment by : National Research Council
Download or read book Phthalates and Cumulative Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2009-01-19 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.
Book Synopsis Molecular Biology and Toxicology of Metals by : Rudolfs K. Zalups
Download or read book Molecular Biology and Toxicology of Metals written by Rudolfs K. Zalups and published by CRC Press. This book was released on 2000-02-24 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology and Toxicology of Metals provides a critical review and analysis of the current state of knowledge of metal ion transport and metabolism in prokaryotic and eukaryotic cellular systems. It covers the latest information on specific metals and the biological molecules with which metals interact. It also details mechanisms in the handling and toxicity of metals in specific organ systems, and the role of metals in cell signalling and gene transcription in target cells. This book is sure to prove a fertile meeting ground for the disciplines of molecular genetics and metal toxicology.
Book Synopsis Alternative Toxicological Methods by : Harry Salem
Download or read book Alternative Toxicological Methods written by Harry Salem and published by CRC Press. This book was released on 2003-03-26 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together the recent and relevant contributions of over 125 scientists from industry, government, and academia in North America and Western Europe, Alternative Toxicological Methods explores the development and validation of replacement, reduction, and refinement alternatives (the 3Rs) to animal testing. Internationally recognized scientist
Author :American Psychiatric Association Publisher :American Psychiatric Publishing ISBN 13 :9780890423066 Total Pages :368 pages Book Rating :4.4/5 (23 download)
Book Synopsis American Psychiatric Association Practice Guidelines by : American Psychiatric Association
Download or read book American Psychiatric Association Practice Guidelines written by American Psychiatric Association and published by American Psychiatric Publishing. This book was released on 1996 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the American Psychiatric Association Practice Guideline series is to improve patient care. Guidelines provide a comprehensive synthesis of all available information relevant to the clinical topic. Practice guidelines can be vehicles for educating psychiatrists, other medical and mental health professionals, and the general public about appropriate and inappropriate treatments. The series also will identify those areas in which critical information is lacking and in which research could be expected to improve clinical decisions. The Practice Guidelines are also designed to help those charged with overseeing the utilization and reimbursement of psychiatric services to develop more scientifically based and clinically sensitive criteria.
Book Synopsis Interconnections Between Human and Ecosystem Health by : R.T. Di Giulio
Download or read book Interconnections Between Human and Ecosystem Health written by R.T. Di Giulio and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecotoxicology is a relatively new scientific discipline. Indeed, it might be argued that it is only during the last 5-10 years that it has come to merit being regarded as a true science, rather than a collection of procedures for protecting the environment through management and monitoring of pollutant discharges into the environment. The term 'ecotoxicology' was first coined in the late sixties by Prof. Truhaut, a toxicologist who had the vision to recognize the importance of investigating the fate and effects of chemicals in ecosystems. At that time, ecotoxicology was considered a sub-discipline of medical toxicology. Subsequently, several attempts have been made to portray ecotoxicology in a more realistic light. Notably, both Moriarty (1988) and F. Ramade (1987) emphasized in their books the broad basis of ecotoxicology, encompassing chemical and radiation effects on all components of ecosystems. In doing so, they and others have shifted concern from direct chemical toxicity to humans, to the far more subtle effects that pollutant chemicals exert on natural biota. Such effects potentially threaten the existence of all life on earth. Although I have identified the sixties as the era when ecotoxicology was first conceived as a coherent subject area, it is important to acknowledge that studies that would now be regarded as ecotoxicological are much older.
