Prioritization of pathogens to guide discovery, research and development of new antibiotics for drug-resistant bacterial infections, including tuberculosis

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Author :
Publisher : World Health Organization
ISBN 13 : 9240026436
Total Pages : 88 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Prioritization of pathogens to guide discovery, research and development of new antibiotics for drug-resistant bacterial infections, including tuberculosis by :

Download or read book Prioritization of pathogens to guide discovery, research and development of new antibiotics for drug-resistant bacterial infections, including tuberculosis written by and published by World Health Organization. This book was released on 2019-04-10 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:

PRIORITIZATION OF PATHOGENS TO GUIDE DISCOVERY, RESEARCH AND DEVELOPMENT OF NEW ANTIBIOTICS FOR DRUG-RESISTANT BACTERIAL INFECTIONS, INCLUDING TUBERCULOSIS.

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis PRIORITIZATION OF PATHOGENS TO GUIDE DISCOVERY, RESEARCH AND DEVELOPMENT OF NEW ANTIBIOTICS FOR DRUG-RESISTANT BACTERIAL INFECTIONS, INCLUDING TUBERCULOSIS. by :

Download or read book PRIORITIZATION OF PATHOGENS TO GUIDE DISCOVERY, RESEARCH AND DEVELOPMENT OF NEW ANTIBIOTICS FOR DRUG-RESISTANT BACTERIAL INFECTIONS, INCLUDING TUBERCULOSIS. written by and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

WHO fungal priority pathogens list to guide research, development and public health action

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Author :
Publisher : World Health Organization
ISBN 13 : 9240060243
Total Pages : 48 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis WHO fungal priority pathogens list to guide research, development and public health action by : World Health Organization

Download or read book WHO fungal priority pathogens list to guide research, development and public health action written by World Health Organization and published by World Health Organization. This book was released on 2022-10-25 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt:

WHO bacterial priority pathogens list, 2024

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Publisher : World Health Organization
ISBN 13 : 924009346X
Total Pages : 72 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis WHO bacterial priority pathogens list, 2024 by : World Health Organization

Download or read book WHO bacterial priority pathogens list, 2024 written by World Health Organization and published by World Health Organization. This book was released on 2024-05-17 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Discovery Targeting Drug-Resistant Bacteria

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Publisher : Academic Press
ISBN 13 : 0128184817
Total Pages : 434 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug Discovery Targeting Drug-Resistant Bacteria by : Prashant Kesharwani

Download or read book Drug Discovery Targeting Drug-Resistant Bacteria written by Prashant Kesharwani and published by Academic Press. This book was released on 2020-05-15 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. Written by scientists with extensive industrial experience in drug discovery Provides a balanced view of the field, including its challenges and future directions Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war

Extending the Cure

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Author :
Publisher : Routledge
ISBN 13 : 1136527605
Total Pages : 193 pages
Book Rating : 4.1/5 (365 download)

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Book Synopsis Extending the Cure by : Ramanan Laxminarayan

Download or read book Extending the Cure written by Ramanan Laxminarayan and published by Routledge. This book was released on 2010-09-30 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our ability to treat common bacterial infections with antibiotics goes back only 65 years. However, the authors of this report make it clear that sustaining a supply of effective and affordable antibiotics cannot be without changes to the incentives facing patients, physicians, hospitals, insurers, and pharmaceutical manufacturers. In fact, increasing resistance to these drugs is already exacting a terrible price. Every day in the United States, approximately 172 men, women, and children die from infections caused by antibiotic-resistant bacteria in hospitals alone. Beyond those deaths, antibiotic resistance is costing billions of dollars through prolonged hospital stays and the need for doctors to resort to ever more costly drugs to use as substitute treatments. Extending the Cure presents the problem of antibiotic resistance as a conflict between individual decision makers and their short-term interest and the interest of society as a whole, in both present and future: The effort that doctors make to please each patient by prescribing a drug when it might not be properly indicated, poor monitoring of discharged patients to ensure that they do not transmit drug-resistant pathogens to other persons, excesses in the marketing of new antibiotics, and the broad overuse of antibiotics all contribute to the development and spread of antibiotic-resistant bacteria. The book explores a range of policy options that would encourage patients, health care providers, and managed care organizations to serve as more responsible stewards of existing antibiotics as well as proposals that would give pharmaceutical firms greater incentives to develop new antibiotics and avoid overselling. If the problem continues unaddressed, antibiotic resistance has the potential to derail the health care system and return us to a world where people of all ages routinely die from simple infections. As a basis for future research and a spur to a critically important dialogue, Extending the Cure is a fundamental first step in addressing this public health crisis. The Extending the Cure project is funded in part by the Robert Wood Johnson Foundation through its Pioneer Portfolio.

First meeting of the WHO Antifungal Expert Group on Identifying Priority Fungal Pathogens

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Publisher : World Health Organization
ISBN 13 : 9240006354
Total Pages : 18 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis First meeting of the WHO Antifungal Expert Group on Identifying Priority Fungal Pathogens by :

Download or read book First meeting of the WHO Antifungal Expert Group on Identifying Priority Fungal Pathogens written by and published by World Health Organization. This book was released on 2020-05-04 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt:

2021 Antibacterial agents in clinical and preclinical development

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Publisher : World Health Organization
ISBN 13 : 9240047654
Total Pages : 104 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis 2021 Antibacterial agents in clinical and preclinical development by : World Health Organization

Download or read book 2021 Antibacterial agents in clinical and preclinical development written by World Health Organization and published by World Health Organization. This book was released on 2022-04-30 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bacterial vaccines in clinical and preclinical development 2021

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Publisher : World Health Organization
ISBN 13 : 9240052453
Total Pages : 92 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Bacterial vaccines in clinical and preclinical development 2021 by : World Health Organization

Download or read book Bacterial vaccines in clinical and preclinical development 2021 written by World Health Organization and published by World Health Organization. This book was released on 2022-07-12 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Target product profiles for needed antibacterial agents

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Publisher : World Health Organization
ISBN 13 : 9240003894
Total Pages : 32 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Target product profiles for needed antibacterial agents by :

Download or read book Target product profiles for needed antibacterial agents written by and published by World Health Organization. This book was released on 2020-04-30 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Technological Challenges in Antibiotic Discovery and Development

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Publisher : National Academies Press
ISBN 13 : 0309298172
Total Pages : 48 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Technological Challenges in Antibiotic Discovery and Development by : National Research Council

Download or read book Technological Challenges in Antibiotic Discovery and Development written by National Research Council and published by National Academies Press. This book was released on 2014-01-27 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technological Challenges in Antibiotic Discovery and Development is the summary of a workshop convened by the Chemical Sciences Roundtable in September 2013 to explore the current state of antibiotic discovery and examine the technology available to facilitate development. Through formal presentations and panel discussions, participants from academia, industry, federal research agencies discussed the technical challenges present and the incentives and disincentives industry faces in antibiotic development, and identified novel approaches to antibiotic discovery. Antibiotic resistance is a serious and growing problem in modern medicine and it is emerging as a pre-eminent public health threat. Each year in the United States alone, at least two million acquire serious infections with bacteria that are resistant to one or more antibiotics, and at least 23,000 people die annually as a direct result of these antibiotic-resistant infections. In addition to the toll on human life, antibiotic-resistant infections add considerable and avoidable costs to the already overburdened U.S. health care system. This report explores the challenges in overcoming antibiotic resistance, screening for new antibiotics, and delivering them to the sites of infection in the body. The report also discusses a path forward to develop the next generation of potent antimicrobial compounds capable of once again tilting the battle against microbial pathogens in favor of humans. Technological Challenges in Antibiotic Discovery and Development gives a broad view of the landscape of antibiotic development and the technological challenges and barriers to be overcome.

2019 Antibacterial agents in clinical development

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Publisher : World Health Organization
ISBN 13 : 9240000194
Total Pages : 48 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis 2019 Antibacterial agents in clinical development by : World Health Organization

Download or read book 2019 Antibacterial agents in clinical development written by World Health Organization and published by World Health Organization. This book was released on 2020-02-20 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt:

New Threats of Antibiotic-Resistant Bacteria and Fungi

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832509355
Total Pages : 118 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis New Threats of Antibiotic-Resistant Bacteria and Fungi by : Xiaojiong Jia

Download or read book New Threats of Antibiotic-Resistant Bacteria and Fungi written by Xiaojiong Jia and published by Frontiers Media SA. This book was released on 2022-12-19 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Antibiotic Discovery and Development

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Publisher : Springer Science & Business Media
ISBN 13 : 1461414008
Total Pages : 1119 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Antibiotic Discovery and Development by : Thomas J. Dougherty

Download or read book Antibiotic Discovery and Development written by Thomas J. Dougherty and published by Springer Science & Business Media. This book was released on 2011-12-18 with total page 1119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.

Implementing the global action plan on antimicrobial resistance

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Author :
Publisher : World Health Organization
ISBN 13 : 924007466X
Total Pages : 197 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Implementing the global action plan on antimicrobial resistance by : World Health Organization

Download or read book Implementing the global action plan on antimicrobial resistance written by World Health Organization and published by World Health Organization. This book was released on 2023-12-12 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt:

WHO implementation handbook for national action plans on antimicrobial resistance

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Author :
Publisher : World Health Organization
ISBN 13 : 9240041982
Total Pages : 80 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis WHO implementation handbook for national action plans on antimicrobial resistance by :

Download or read book WHO implementation handbook for national action plans on antimicrobial resistance written by and published by World Health Organization. This book was released on 2022-02-28 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2015 the World Health Assembly endorsed the Global action plan on antimicrobial resistance calling on countries to develop and implement national action plans on antimicrobial resistance (AMR). For most countries, the greatest challenge is not developing a national action plan; rather, it is the implementation of the plan based on evidence-based prioritization of activities, systematic monitoring of progress, and ensuring sustainability of efforts. The purpose of this publication is to to provide a practical, stepwise approach to the implementation of the national action plan on AMR within the human health sector; and to provide a process and collation of existing WHO tools to prioritize, cost, implement, monitor and evaluate national action plan activities. The target audience of the publication are national/subnational stakeholders working on AMR within the human health sector. This includes national health authorities, national multisectoral coordination groups, senior technical experts and policymakers involved in implementing AMR activities at all levels of the health system, and implementation partners to accelerate sustainable implementation and monitoring and evaluation of national action plans on AMR.

Antibiotics

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Publisher : What Everyone Needs to Know(r)
ISBN 13 : 0190663413
Total Pages : 433 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis Antibiotics by : Mary E. Wilson

Download or read book Antibiotics written by Mary E. Wilson and published by What Everyone Needs to Know(r). This book was released on 2019 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually everyone has taken antibiotics. They can be lifesavers -- and they can be useless. What are they? How are they used? And what happens as the effectiveness of antibiotics continues to decline? Antibiotics: What Everyone Needs to Know(R) examines the personal and societal implications of our planet's most important -- and frequently misused -- medications. In a question-and-answer format, it unpacks the most complicated aspects of this issue, including: How antibiotics are used (and overused) in humans, plants, and livestock; the causes and consequences of bacterial resistance to antibiotics; how the globalized world enables antibiotic resistance to spread quickly; and the difficult decisions ahead for both medical care and the food system. Grounded in the latest scientific research and crafted for general readers, Antibiotics: What Everyone Needs to Know(R) offers a clear-eyed overview of where we are, and what the future holds, as antibiotics lose their power.