Principles of Nutrigenetics and Nutrigenomics

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Publisher : Academic Press
ISBN 13 : 0128045876
Total Pages : 588 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Principles of Nutrigenetics and Nutrigenomics by : Raffaele De Caterina

Download or read book Principles of Nutrigenetics and Nutrigenomics written by Raffaele De Caterina and published by Academic Press. This book was released on 2019-09-22 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. - Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics - Includes a valuable guide to ethics for genetic testing for nutritional advice - Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts - Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book

Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition

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Author :
Publisher : CRC Press
ISBN 13 : 1439876819
Total Pages : 439 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition by : Lynnette R. Ferguson

Download or read book Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition written by Lynnette R. Ferguson and published by CRC Press. This book was released on 2016-04-19 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: While functional foods have become a reasonably well-established concept, personalized nutrition is still treated with skepticism by many. The recognition that people would have different nutrient requirements, or perceive foods in different ways, raises several concerns-some real, some not so real. Nutrigenomics and Nutrigenetics in Functional Foo

Nutrigenetics

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Publisher : Academic Press
ISBN 13 : 0123859018
Total Pages : 397 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Nutrigenetics by : Martin Kohlmeier

Download or read book Nutrigenetics written by Martin Kohlmeier and published by Academic Press. This book was released on 2012-12-31 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrigenetics: Applying the Science of Personal Nutrition provides a fully referenced, readable guide to understanding the rationale and importance of nutrigenetic applications and explains why single nutrition recommendations will not fit everybody or even a majority of modern humans. This books explains how genetic variation shapes individual nutrition requirements and sensitivities, presents questions to ask about reported gene-nutrient interactions, and what needs to be done before putting nutrigenetic tests to practical use. This book blends key concepts from the fields of genetics, biochemistry, epidemiology, public health, and clinical medicine to give a rich perspective on the genetically diverse nutritional needs and sensitivities of individuals in health and disease. A steadily increasing number of people order genetic tests to find out what they should eat for better health, well being and performance, and an even greater number asks their healthcare providers about such tests. Most of the currently offered tests are not grounded in current knowledge, often absurdly so, but few professionals can explain why they are misguided. On the other hand, there are more evidence-supported genetic variants that can guide nutrition decisions, but again most healthcare providers know little about them, much less use them in their daily practice. There is a great need for a solidly evidence-based yet accessible book that explains the science of nutrigenetics and provides the tools to evaluate new nutrigenetic tests. - Comprehensive coverage of the emerging science of nutritional genetics and its promise for individually tailored nutrition guidance - Presents practical examples to enhance comprehension and spur additional research - Offers a logical progression from what nutrigenetics is, to its possibilities in enhancing health

Nutrigenomics and the Future of Nutrition

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Author :
Publisher : National Academies Press
ISBN 13 : 0309477646
Total Pages : 155 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Nutrigenomics and the Future of Nutrition by : National Academies of Sciences, Engineering, and Medicine

Download or read book Nutrigenomics and the Future of Nutrition written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-08-27 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: On December 5, 2017, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop titled Nutrigenomics and the Future of Nutrition in Washington, DC, to review current knowledge in the field of nutrigenomics as it relates to nutrition. Workshop participants explored the influence of genetic and epigenetic expression on nutritional status and the potential impact of personalized nutrition on health maintenance and chronic disease prevention. This publication summarizes the presentations and discussions from the workshop.

Nutritional Genomics

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Publisher : John Wiley & Sons
ISBN 13 : 0471781789
Total Pages : 506 pages
Book Rating : 4.4/5 (717 download)

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Book Synopsis Nutritional Genomics by : Jim Kaput

Download or read book Nutritional Genomics written by Jim Kaput and published by John Wiley & Sons. This book was released on 2006-04-28 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive guide to the basic principles and latest advances in Nutritional Genomics Though still in its infancy, nutritional genomics, or "nutrigenomics," has revealed much about the complex interactions between diet and genes. But it is in its potential applications that nutrigenomics promises to revolutionize the ways we manage human health and combat disease in the years ahead. Great progress already has been made in modeling "personalized" nutrition for optimal health and longevity as well as in genotype-based dietary interventions for the prevention, mitigation, or possible cure of a variety of chronic diseases and some types of cancer. Topics covered include: * Nutrients and gene expression * The role of metabolomics in individualized health * Molecular mechanisms of longevity regulation and calorie restriction * Green tea polyphenols and soy peptides in cancer prevention * Maternal nutrition and fetal gene expression * Genetic susceptibility to heterocyclic amines from cooked foods * Bioinformatics and biocomputation in nutrigenomics * The pursuit of optimal diets Written by an all-star team of experts from around the globe, this volume provides an integrated overview of the cutting-edge field of nutritional genomics. The authors and editors lead an in-depth discussion of the fundamental principles and scientific methodologies that serve as the foundation for nutritional genomics and explore important recent advances in an array of related disciplines. Each self-contained chapter builds upon its predecessor, leading the reader seamlessly from basic principles to more complex scientific findings and experimental designs. Scientific chapters are carefully balanced with those addressing the social, ethical, regulatory, and commercial implications of nutrigenomics.

Nutritional Genomics

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Author :
Publisher : CRC Press
ISBN 13 : 1439844534
Total Pages : 448 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Nutritional Genomics by : Wayne R. Bidlack

Download or read book Nutritional Genomics written by Wayne R. Bidlack and published by CRC Press. This book was released on 2016-04-19 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: The notion of matching diet with an individual's genetic makeup is transforming the way the public views nutrition as a means of managing health and preventing disease. To fulfill the promise of nutritional genomics, researchers are beginning to reconcile the diverse properties of dietary factors with our current knowledge of genome structure and g

Personalized Nutrition

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805594275
Total Pages : 201 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Personalized Nutrition by : Artemis P. Simopoulos

Download or read book Personalized Nutrition written by Artemis P. Simopoulos and published by Karger Medical and Scientific Publishers. This book was released on 2010 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Awareness of the influence of our genetic variation to dietary response (nutrigenetics) and how nutrients may affect gene expression (nutrigenomics) is prompting a revolution in the field of nutrition. Nutrigenetics/Nutrigenomics provide powerful approaches to unravel the complex relationships among nutritional molecules, genetic variants and the biological system. This publication contains selected papers from the '3rd Congress of the International Society of Nutrigenetics/Nutrigenomics' held in Bethesda, Md., in October 2009. The contributions address frontiers in nutrigenetics, nutrigenomics, epigenetics, transcriptomics as well as non-coding RNAs and posttranslational gene regulations in various diseases and conditions. In addition to scientific studies, the challenges and opportunities facing governments, academia and the industry are included. Everyone interested in the future of personalized medicine and nutrition or agriculture, as well as researchers in academia, government and industry will find this publication of the utmost interest for their work.

Genomic Medicine

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Publisher : Oxford Monographs on Medical G
ISBN 13 : 019989602X
Total Pages : 853 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Genomic Medicine by : Dhavendra Kumar

Download or read book Genomic Medicine written by Dhavendra Kumar and published by Oxford Monographs on Medical G. This book was released on 2014-10-15 with total page 853 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preceded by Genomics and clinical medicine / edited by Dhavendra Kumar. [First edition]. 2008.

Nutrient Metabolism

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Publisher : Academic Press
ISBN 13 : 0123877881
Total Pages : 899 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Nutrient Metabolism by : Martin Kohlmeier

Download or read book Nutrient Metabolism written by Martin Kohlmeier and published by Academic Press. This book was released on 2015-05-12 with total page 899 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrient Metabolism, Second Edition, provides a comprehensive overview of the supply and use of nutrients in the human body and how the body regulates intake. Chapters detail the principles determining digestion and absorption of food ingredients and how these compounds and their metabolites get into the brain, cross the placenta and pass through the kidneys. Each nutrient's coverage contains a nutritional summary that describes its function, its food sources, dietary requirements, potential health risks if deficient, and impact of excessive intake. This handbook contains the latest information on the scope of structures, processes, genes and cofactors involved in maintaining a healthy balance of nutrient supplies. Of interest to a wide range of professionals because nutrient issues connect to so many audiences, the book contains a useful link to dietary supplements. - Latest research findings on health and clinical effects of nutrients and of interventions affecting nutrient supply or metabolism - Each nutrient covered contains a nutritional summary describing its function, food sources, dietary requirements, potential health risks if deficient, and impact of excessive intake. - Nutrient information immediately accessible--from source to effect--in one volume

Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery

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Author :
Publisher : Elsevier
ISBN 13 : 0323859623
Total Pages : 598 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery by : Genevieve Dable-Tupas

Download or read book Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery written by Genevieve Dable-Tupas and published by Elsevier. This book was released on 2022-10-15 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery presents novel insights into how these tools can be applied in the study of nutrient-gene interaction for the management of certain disease conditions without using synthetic drugs or other treatments that come with side effects. Divided into three parts, Part I presents chapters that give background information of the subject while laying a framework for other chapters to follow. Part II presents chapters that discuss the role of nutrigenomics in healthcare, while Part III presents chapters that discuss the role of nutrigenomics in modern day drug discovery. Written by a global team of experts from key institutions around the world, this book is useful for drug developers, medicinal chemists, public health scientists, molecular biologists, biochemists, toxicologists and food scientists. - Provides readers with background information on the role of nutrigenomics in healthcare, with a focus on emerging topics in nutrigenetics and nutrigenomics - Presents chapters that discusses the role of nutrigenomics in the modern day drug discovery for the treatment and management of diseases - Includes a wide array of definitions, methods, summaries, figures and tables to aid readers with understanding and application

Nutrigenomics: How Science Works

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Publisher : Springer Nature
ISBN 13 : 303036948X
Total Pages : 195 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Nutrigenomics: How Science Works by : Carsten Carlberg

Download or read book Nutrigenomics: How Science Works written by Carsten Carlberg and published by Springer Nature. This book was released on 2020-02-14 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fascinating area of Nutrigenomics describes this daily communication between our diet and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often associated with low-grade chronic inflammation. Overnutrition paired with physical inactivity leads to overweight and obesity and results in increased burden for a body that originally was adapted for a life in the savannahs of East Africa. Therefore, this textbook does not discuss a theoretical topic in science, but it talks about real life and our life-long “chat” with diet. We are all food consumers, thus each of us is concerned by the topic of this book and should be aware of its mechanisms. The purpose of this book is to provide an overview on the principles of nutrigenomics and their relation to health or disease. The content of this book is based on the lecture course “Nutrigenomics”, which is held since 2003 once per year by Prof. Carlberg at the University of Eastern Finland in Kuopio. The book represents an updated but simplified version of our textbook “Nutrigenomics” (ISBN 978-3-319-30413-7). Besides its value as a textbook, “Nutrigenomics: how science works” will be a useful reference for individuals working in biomedicine

Nutritional Oncology

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Publisher : Elsevier
ISBN 13 : 0080454178
Total Pages : 847 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Nutritional Oncology by : George L. Blackburn

Download or read book Nutritional Oncology written by George L. Blackburn and published by Elsevier. This book was released on 2011-05-02 with total page 847 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutritional oncology is an increasingly active interdisciplinary field where cancer is investigated as both a systemic and local disease originating with the changes in the genome and progressing through a multi-step process which may be influenced at many points in its natural history by nutritional factors that could impact the prevention of cancer, the quality of life of cancer patients, and the risk of cancer recurrence in the rapidly increasing population of cancer survivors.Since the first edition of this book was published in 1999, the idea that there is a single gene pathway or single drug will provide a cure for cancer has given way to the general view that dietary/environmental factors impact the progression of genetic and cellular changes in common forms of cancer. This broad concept can now be investigated within a basic and clinical research context for specific types of cancer. This book attempts to cover the current available knowledge in this new field of nutritional oncology written by invited experts. This book attempts to provide not only the theoretical and research basis for nutritional oncology, but will offer the medical oncologist and other members of multidisciplinary groups treating cancer patients practical information on nutrition assessment and nutritional regimens, including micronutrient and phytochemical supplementation. The editors hope that this volume will stimulate increased research, education and patient application of the principles of nutritional oncology.NEW TO THIS EDITION:* Covers hot new topics of nutrigenomics and nutrigenetics in cancer cell growth * Includes new chapters on metabolic networks in cancer cell growth, nutrigenetics and nutrigenomics* Presents substantially revised chapters on breast cancer and nutrition, prostate cancer and nutrition, and colon cancer and nutrition* Includes new illustrations throughout the text, especially in the breast cancer chapter* Includes integrated insights into the unanswered questions and clearly defined objectives of research in nutritional oncology * Offers practical guidelines for clinicians advising malnourished cancer patients and cancer survivors on diet, nutrition, and lifestyle * Provides information on the role of bioactive substances, dietary supplements, phytochemicals and botanicals in cancer prevention and treatment

Phytochemicals

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Publisher : CRC Press
ISBN 13 : 1420005901
Total Pages : 233 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Phytochemicals by : Mark S. Meskin

Download or read book Phytochemicals written by Mark S. Meskin and published by CRC Press. This book was released on 2006-02-22 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding phytochemical-gene interactions provides the basis for individualized therapies to promote health as well as prevent and treat disease. The authors of Phytochemicals: Nutrient-Gene Interactions examine the interactions between phytochemicals and the human genome and discuss the impact these interactions have on health, aging, a

Nutrigenetics and Nutrigenomics

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805577826
Total Pages : 337 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Nutrigenetics and Nutrigenomics by : Artemis P. Simopoulos

Download or read book Nutrigenetics and Nutrigenomics written by Artemis P. Simopoulos and published by Karger Medical and Scientific Publishers. This book was released on 2004-01-01 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the first time, international scientists describe the advances in genetics and nutrition by combining methods of molecular biology with those of functional genetics, also known as systems biology. This book provides the latest data on genetic variation and dietary response, nutrients and gene expression, and the contribution molecular biology has given to systems biology. It also includes a comprehensive critique of genetic association studies in defining the risk of chronic diseases and concludes that molecular diagnostic tests will eventually affect every area of health care from individual risk prediction, early diagnosis of disease, and determination of optimal treatment regimens, to monitoring treatment effectiveness. The appendix contains an extensive glossary of the newly emerging terminology, as well as recommendations for genetic screening. This publication is an essential tool for the future work of all physicians, nutritionists, dietitians, geneticists, physiologists, molecular biologists, anthropologists, food technologists, policy makers, ethicists and educators.

Conceptualizing Plant-Based Nutrition

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Publisher : Springer Nature
ISBN 13 : 981194590X
Total Pages : 282 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Conceptualizing Plant-Based Nutrition by : Ramesh S. V.

Download or read book Conceptualizing Plant-Based Nutrition written by Ramesh S. V. and published by Springer Nature. This book was released on 2022-10-10 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deliberates on the various aspects of plant-based nutrition. Plant-based nutrition has numerous potential health benefits as it is low on calories nevertheless high on nutrient density and satiety, and also nutrient supplementation makes them wholesome diets.Starting with the importance of biodiversity contributing to the nutrition, the book discusses the development or utilization of nutrient-dense crops/foods with their bioavailability properties and health effects. Further, it deals with the enrichment of micronutrients through bio-fortification, fortification, the role of food matrix, and nutrient bioavailability, including the role of plant-based milk alternatives. The linkage between food and health is also being discussed in the context of anti-nutritional factors, metabolic fate of the food, and genomics. Finally, the implications of next-gen biotech crops and food safety issues imperative to define the concept of safe nutrition are discussed.With contributions from plant nutrition experts, this book serves as a one-stop reference for plant scientists, food technologists, and nutritionists looking to understand the concept of plant-based nutrition and its linkage with human health.

The Healthy Bones Plant-Based Nutrition Plan and Cookbook

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Author :
Publisher : Chelsea Green Publishing
ISBN 13 : 1645022277
Total Pages : 535 pages
Book Rating : 4.6/5 (45 download)

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Book Synopsis The Healthy Bones Plant-Based Nutrition Plan and Cookbook by : Dr. Laura Kelly

Download or read book The Healthy Bones Plant-Based Nutrition Plan and Cookbook written by Dr. Laura Kelly and published by Chelsea Green Publishing. This book was released on 2024-09-05 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique nutritional guide and cookbook—with over 100 delicious recipes—that can help both women and men of any age maintain optimal bone density and prevent osteoporosis. Can you have healthy bones while following a diet of more, mostly, or entirely plants? Is lower bone density an inescapable price even young people must pay for choosing plant foods? Dr. Laura Kelly, a specialist in precision medicine for bone health, hears these questions from patients and colleagues who cite studies showing that as a group, vegetarians and vegans can have lower bone density than do people who eat animal food. In The Healthy Bones Plant-Based Nutrition Plan and Cookbook, Dr. Kelly puts these questions to rest, offering readers the same expert guidance she provides to her patients who are on a plant-forward or vegetarian diet, ensuring they have a plan to meet their nutritional needs for healthy bones or working toward reversal of bone loss. She explains why people on plant-forward, vegetarian, or vegan diets sometimes struggle with low bone density; identifies the environmental factors that can influence bone health; and explains how to minimize the risks while setting out the steps anyone can take to restore, improve, and maintain bone density. As the authors of The Healthy Bones Nutrition Plan and Cookbook, Laura and Helen Kelly specialize in explaining science to nonscientists, and this book is a must-have for anyone who is giving plant foods a bigger share—or a full share—of their daily diet. The authors guide readers to learn about the wide variety of plant foods and how to select, prepare, and cook with them, as well as best food combinations in order to achieve optimum bone health. The Healthy Bones Plant-Based Nutrition Plan and Cookbook breaks new ground by including: Complete information on the abundant nutrition that plant foods offer and an explanation of how plant foods alone can help to strengthen the skeleton. An explanation of exciting research discoveries regarding gene expression and the use of genetic testing to help those struggling with bone loss. The new sciences of nutrigenetics and nutrigenomics allow practitioners to understand how a patient’s genetic profile contributes to bone density and how detailed nutrient and food prescriptions can either prevent or treat osteoporosis in an elegant and efficient way. The reasons why bone strength and density decline with age, and the type of nutrient interventions that can help restore turnover balance. How to meet and overcome the challenges to nutrient bioavailability posed by choosing a fully plant-based life. A discussion of the A to Z of bioavailability of nutrients most important for bone health, from calcium to Vitamin K2, and how to release the nutrients in plant foods from the antinutrients that can lock them in undigestible forms. Over 100 recipes created by gifted vegetarian chef Jummee Park that feature delicious and diverse combinations of vegetables, fruits, grains, mushrooms, nuts, beans, seeds, edible flowers, and spices. Tips on establishing a pantry and several example meal plans. How to use an online nutrition calculator to craft your own delicious plant combinations that supply needed amounts of complete protein, iron, and vitamins A and B12 for whole nutrition. The Healthy Bones Plant-Based Nutrition Plan and Cookbook is a unique nutritional guide and cookbook that can help both women and men of any age maintain optimal bone density and prevent osteoporosis on a plant-based, vegetarian, or vegan diet. The book’s full presentation of the science of bone health, along with a generous helping of recipes, follows the example of the Kellys’ first book to inspire confidence in and enthusiasm for making the changes required to embrace food as medicine for bones.

Principles of Gender-Specific Medicine

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Author :
Publisher : Academic Press
ISBN 13 : 0128035420
Total Pages : 794 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Principles of Gender-Specific Medicine by : Marianne Legato J

Download or read book Principles of Gender-Specific Medicine written by Marianne Legato J and published by Academic Press. This book was released on 2017-05-15 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Winner of the 2018 PROSE Award in Clinical Medicine from the Association of American Publishers! - 2018 PROSE Awards - Winner, Award for Clinical Medicine: Association of American Publishers - Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness - Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease - Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself - Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols