Principles of Metabolic Control in Mammalian Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 1461330068
Total Pages : 678 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Principles of Metabolic Control in Mammalian Systems by : Herman

Download or read book Principles of Metabolic Control in Mammalian Systems written by Herman and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this work we present the basic principles of metabolic control which we hope will serve as a foundation for the vast array of factual matter which the biochemist and the physician engaged in metabolic research must accumulate. Accordingly, we attempt to set forth these principles, along with sufficient explanation, so that the reader may apply them to the ever-expanding literature of biochemistry. If we are successful, this will provide a theoretical approach which can be applied to any given set of metabolic reactions. It is impossible to enumerate each and every biochemical reaction and pathway since such a work would be too unwieldy for efficient use. Rather, we hope our presentation of the principles of metabolic control will be sufficiently basic to be of lasting usefulness no matter how detailed biochemistry may become. We would like to be able to con dense biochemistry into a theoretical biology that will not only allow for the general treatment of any given reaction but will enable predic tions to be made as to the existence of necessary pathways and the con sequences of altered control. Such is not possible today, but this may be accomplished in the future. We believe it is now possible to institute the beginnings of such a theoretical biology.

Metabolic Regulation in Mammals

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Author :
Publisher : CRC Press
ISBN 13 : 9780203381038
Total Pages : 256 pages
Book Rating : 4.3/5 (81 download)

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Book Synopsis Metabolic Regulation in Mammals by : David Gibson

Download or read book Metabolic Regulation in Mammals written by David Gibson and published by CRC Press. This book was released on 2003-09-02 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Regulation in Mammals presents the basic principles of metabolic control, based on investigations conducted during the past twenty years. It explains the impact of recent advances in cell biology, molecular biology and genetics on the field. Beginning with the basic concepts, this text covers all angles of metabolic regulation, including blood caloric homeostasis, cardiac and skeletal muscle, adipose tissue, and liver metabolism. Review questions, summary sections and worked examples help break down the complexity of the subject and allow the reader to review the principles and concepts presented. Details of metabolic pathways are provided for each body system, with accompanying charts to provide the reader with an overall perspective. This text is ideal for undergraduates across a range of biological and health science disciplines, particularly those taking one or two semester courses in metabolic regulation.

Metabolic Regulation In Mammals

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Author :
Publisher : Turtleback
ISBN 13 : 9780613917834
Total Pages : pages
Book Rating : 4.9/5 (178 download)

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Book Synopsis Metabolic Regulation In Mammals by : David M. Gibson

Download or read book Metabolic Regulation In Mammals written by David M. Gibson and published by Turtleback. This book was released on 2002-01-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Regulation in Mammals presents the basic principles of metabolic control, based on investigations conducted during the past twenty years. It explains the impact of recent advances in cell biology, molecular biology and genetics on the field. Beginning with the basic concepts, this text covers all angles of metabolic regulation, including blood caloric homeostasis, cardiac and skeletal muscle, adipose tissue, and liver metabolism. Review questions, summary sections and worked examples help break down the complexity of the subject and allow the reader to review the principles and concepts presented. Details of metabolic pathways are provided for each body system, with accompanying charts to provide the reader with an overall perspective. This text is ideal for undergraduates across a range of biological and health science disciplines, particularly those taking one or two semester courses in metabolic regulation.

Metabolic Regulation in Mammals

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Publisher : CRC Press
ISBN 13 : 9780415267564
Total Pages : 240 pages
Book Rating : 4.2/5 (675 download)

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Book Synopsis Metabolic Regulation in Mammals by : David Gibson

Download or read book Metabolic Regulation in Mammals written by David Gibson and published by CRC Press. This book was released on 2001-11-22 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Regulation in Mammals presents the basic principles of metabolic control, based on investigations conducted during the past twenty years. It explains the impact of recent advances in cell biology, molecular biology and genetics on the field. Beginning with the basic concepts, this text covers all angles of metabolic regulation, including blood caloric homeostasis, cardiac and skeletal muscle, adipose tissue, and liver metabolism. Review questions, summary sections and worked examples help break down the complexity of the subject and allow the reader to review the principles and concepts presented. Details of metabolic pathways are provided for each body system, with accompanying charts to provide the reader with an overall perspective. This text is ideal for undergraduates across a range of biological and health science disciplines, particularly those taking one or two semester courses in metabolic regulation.

Functional Metabolism

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Publisher : John Wiley & Sons
ISBN 13 : 0471675571
Total Pages : 640 pages
Book Rating : 4.4/5 (716 download)

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Book Synopsis Functional Metabolism by : Kenneth B. Storey

Download or read book Functional Metabolism written by Kenneth B. Storey and published by John Wiley & Sons. This book was released on 2005-02-25 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Metabolism of Cells is the first comprehensive survey of metabolism, offering an in-depth examination of metabolism and regulation of carbohydrates, lipids, and amino acids. It provides a basic background on metabolic regulation and adaptation as well as the chemical logic of metabolism, and covers the interrelationship of metabolism to life processes of the whole organism. The book lays out a structured approach to the metabolic basis of disease, including discussion of the normal pathways of metabolism, altered pathways leading to disease, and use of molecular genetics in diagnosis and treatment of disease. It also takes a unique comparative approach in which human metabolism is a reference for metabolism in microorganisms and plant design, and presents novel coverage of development and aging, and human health and animal adaptation. The final chapter reviews the past and future promise of new genetic approaches to treatment and bioinformatics. This, the most exhaustive treatment of metabolism currently available, is a useful text for advanced undergraduates and graduates in biochemistry, cell/molecular biology, and biomedicine, as well as biochemistry instructors and investigators in related fields.

Prokaryotic Metabolism and Physiology

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Publisher : Cambridge University Press
ISBN 13 : 1107171733
Total Pages : 509 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Prokaryotic Metabolism and Physiology by : Byung Hong Kim

Download or read book Prokaryotic Metabolism and Physiology written by Byung Hong Kim and published by Cambridge University Press. This book was released on 2019-05-16 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.

Molecular Biology of the Cell

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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Metabolic Regulation

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Publisher : Wiley-Blackwell
ISBN 13 : 9780632017010
Total Pages : 299 pages
Book Rating : 4.0/5 (17 download)

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Book Synopsis Metabolic Regulation by : B. Richard Martin

Download or read book Metabolic Regulation written by B. Richard Martin and published by Wiley-Blackwell. This book was released on 1986-12-31 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Structural and Organizational Aspects of Metabolic Regulation

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Publisher :
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Structural and Organizational Aspects of Metabolic Regulation by : Paul A. Srere

Download or read book Structural and Organizational Aspects of Metabolic Regulation written by Paul A. Srere and published by . This book was released on 1990 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Working from a multidisciplinary vantage point, this work reports on significant advances in the area of metabolic control, investigating theories that now include interacting enzymes, the concept of flux control, and the knowledge that single ``pacemaker'' enzymes are rarely found in metabolism. New methods are highlighted, such as the use of anti-idiotypic antibodies, electrophoresis in the presence of immobilized enzymes, and the use of molecular genetics in the study of metabolic regulation.

Understanding the Control of Metabolism

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Publisher :
ISBN 13 :
Total Pages : 301 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis Understanding the Control of Metabolism by : David Fell

Download or read book Understanding the Control of Metabolism written by David Fell and published by . This book was released on 1997 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Metabolic Regulation

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Publisher : Wiley-Blackwell
ISBN 13 :
Total Pages : 316 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Metabolic Regulation by : B. R. Martin

Download or read book Metabolic Regulation written by B. R. Martin and published by Wiley-Blackwell. This book was released on 1987 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides senior undergraduate and graduate students taking courses in biochemistry with an up-to-date description of the regulation of mammalian metabolism. Emphasis is placed on the mechanisms involved, an aspect which is poorly covered by existing texts. The book is divided into three sections, the first two of which describe in detail the mechanisms by which the metabolism of a cell is regulated by both internal and external factors. In the last section these molecular mechanisms are related to physiological regulation of individual tissues and the integration of the response of individual tissues to changes in the state of the whole organism

Regulation of Tissue Oxygenation, Second Edition

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Publisher : Biota Publishing
ISBN 13 : 1615047212
Total Pages : 117 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Regulation of Tissue Oxygenation, Second Edition by : Roland N. Pittman

Download or read book Regulation of Tissue Oxygenation, Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Systems Metabolic Engineering

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Publisher : Springer Science & Business Media
ISBN 13 : 9400745346
Total Pages : 391 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Systems Metabolic Engineering by : Christoph Wittmann

Download or read book Systems Metabolic Engineering written by Christoph Wittmann and published by Springer Science & Business Media. This book was released on 2012-06-15 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.

Metabolic Engineering

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Publisher : John Wiley & Sons
ISBN 13 : 352782345X
Total Pages : 1075 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Metabolic Engineering by : Sang Yup Lee

Download or read book Metabolic Engineering written by Sang Yup Lee and published by John Wiley & Sons. This book was released on 2021-06-02 with total page 1075 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.

Yeast Metabolic Engineering

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Publisher : Humana Press
ISBN 13 : 9781493905621
Total Pages : 0 pages
Book Rating : 4.9/5 (56 download)

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Book Synopsis Yeast Metabolic Engineering by : Valeria Mapelli

Download or read book Yeast Metabolic Engineering written by Valeria Mapelli and published by Humana Press. This book was released on 2014-04-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Yeast Metabolic Engineering: Methods and Protocols provides the widely established basic tools used in yeast metabolic engineering, while describing in deeper detail novel and innovative methods that have valuable potential to improve metabolic engineering strategies in industrial biotechnology applications. Beginning with an extensive section on molecular tools and technology for yeast engineering, this detailed volume is not limited to methods for Saccharomyces cerevisiae, but describes tools and protocols for engineering other yeasts of biotechnological interest, such as Pichia pastoris, Hansenula polymorpha and Zygosaccharomyces bailii. Tools and technologies for the investigation and determination of yeast metabolic features are described in detail as well as metabolic models and their application for yeast metabolic engineering, while a chapter describing patenting and regulations with a special glance at yeast biotechnology closes the volume. Written in the highly successful Methods in Molecular Biology series format, most chapters include an introduction to their respective topic, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Yeast Metabolic Engineering: Methods and Protocols aims to familiarize researchers with the current state of these vital and increasingly useful technologies.

Bacterial Cellular Metabolic Systems

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Publisher : Elsevier
ISBN 13 : 1908818204
Total Pages : 497 pages
Book Rating : 4.9/5 (88 download)

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Book Synopsis Bacterial Cellular Metabolic Systems by : K. Shimizu

Download or read book Bacterial Cellular Metabolic Systems written by K. Shimizu and published by Elsevier. This book was released on 2013-03-26 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: The metabolic regulation of a cell system is of critical importance in systems biology, and a robust model of these mechanisms is essential in predicting the effects on the metabolism of both the culture environment and the knockout of specific genes. Bacterial cellular metabolic systems focuses on this highly topical subject in relation to culture environment and provides a detailed analysis from gene level to metabolic level regulation, as well as offering a discussion of the most recent modelling approaches. The book begins with an introduction to metabolic mechanisms and to the metabolic regulation of a cell, before moving on to discussing the action of global regulators in response to a specific culture environment. The second half of the book examines conventional flux balance analysis and its applications, 13C-metabolic flux analysis, and the effect of a specific gene knockout on the metabolism. - Comprehensive account of metabolic regulation via global regulators in response to changes in the culture environment - Basic formulation of 13C-metabolic flux analysis based on 13C-labelling experiments - Systems biology approach for the modelling and computer simulation of the main metabolic pathways of a cell system

Biochemistry for the Medical Sciences

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Author :
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 990 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Biochemistry for the Medical Sciences by : E. A. Newsholme

Download or read book Biochemistry for the Medical Sciences written by E. A. Newsholme and published by John Wiley & Sons. This book was released on 1988 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: