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Principles Of Medicinal Chemistry Volume I
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Book Synopsis Foye's Principles of Medicinal Chemistry by : Thomas L. Lemke
Download or read book Foye's Principles of Medicinal Chemistry written by Thomas L. Lemke and published by Lippincott Williams & Wilkins. This book was released on 2012-01-24 with total page 1521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acclaimed by students and instructors alike, Foye's Principles of Medicinal Chemistry is now in its Seventh Edition, featuring updated chapters plus new material that meets the needs of today's medicinal chemistry courses. This latest edition offers an unparalleled presentation of drug discovery and pharmacodynamic agents, integrating principles of medicinal chemistry with pharmacology, pharmacokinetics, and clinical pharmacy. All the chapters have been written by an international team of respected researchers and academicians. Careful editing ensures thoroughness, a consistent style and format, and easy navigation throughout the text.
Book Synopsis Foye's Principles of Medicinal Chemistry by : David A. Williams
Download or read book Foye's Principles of Medicinal Chemistry written by David A. Williams and published by Lippincott Williams & Wilkins. This book was released on 2002 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive Fifth Edition has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. The new emphasis is on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. Approximately 45 contributors, respected in the field of pharmacy education, augment this exhaustive reference. New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more. Over 700 illustrations supplement this must-have resource.
Book Synopsis Principles of Medicinal Chemistry Volume-I by : Dr. S. S. Kadam
Download or read book Principles of Medicinal Chemistry Volume-I written by Dr. S. S. Kadam and published by Pragati Books Pvt. Ltd.. This book was released on 2013-05 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1.General Principles2. Topical Anti-Infective Agents3.Chemotherapy of Parasitic Diseases 4.Sulphonamides and Urinary Tract Antiseptic gents 5.Antibiotics 6.Modes of Action of Antibiotics 7.Antifungal Agents 8.Antiviral Agents 9.Anti-Neoplastic Agents 10.Anti-Tuberculosis and Anti-Leprotic Agents 11.Hormones 12.Insulin and Oral Hypoglycemic Agents 13.Diuretics 14.Drugs Acting on Blood 15.Drugs Acting on GIT 16.Drugs Acting on Respiratory Tract 17.Diagnostic Agents 18.Immuno-Modulators 19.Adverse Effects 20.Quantitative Structure Activity Relationship 21.Vitamins Synthesis of Drugs (Appendix) Index
Book Synopsis Basic Concepts in Medicinal Chemistry by : Marc Harrold
Download or read book Basic Concepts in Medicinal Chemistry written by Marc Harrold and published by ASHP. This book was released on 2013-01-18 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.
Book Synopsis Natural Products in Medicinal Chemistry by : Stephen Hanessian
Download or read book Natural Products in Medicinal Chemistry written by Stephen Hanessian and published by John Wiley & Sons. This book was released on 2013-12-18 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new drugs with improved properties over their progenitors. The examples are chosen so as to represent a wide range of natural products with therapeutic relevance among others, as anticancer agents, antimicrobials, antifungals, antisense nucleosides, antidiabetics, and analgesics. From the content: * Part I: Natural Products as Sources of Potential Drugs and Systematic Compound Collections * Part II: From Marketed Drugs to Designed Analogs and Clinical Candidates * Part III: Natural Products as an Incentive for Enabling Technologies * Part IV: Natural Products as Pharmacological Tools * Part V: Nature: The Provider, the Enticer, and the Healer
Book Synopsis Quantum Medicinal Chemistry by : Paolo Carloni
Download or read book Quantum Medicinal Chemistry written by Paolo Carloni and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational methods are transforming the work of chemical and pharmaceutical laboratories. Increasingly faster and more exact simulation algorithms have made quantum chemistry a valuable tool in the search for active substances. Written by a team of leading international quantum chemists, this book is aimed at both beginners as well as experienced users of quantum chemical methods. All commonly used quantum chemical methods are treated here, including Density Functional Theory, quantum and molecular mechanical approaches. Numerous examples illustrate the use of these methods for dealing with problems in pharmaceutical practice, whether the study of inhibitor binding, identifying the surface load of active substances or deriving molecular descriptors using quantum chemical tools. For anyone striving to stay ahead in this rapidly evolving field.
Book Synopsis PRINCIPLES OF MEDICINAL CHEMISTRY Vol. - II by : Dr. S. S. Kadam
Download or read book PRINCIPLES OF MEDICINAL CHEMISTRY Vol. - II written by Dr. S. S. Kadam and published by Pragati Books Pvt. Ltd.. This book was released on 2007-07 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Handbook of Medicinal Chemistry by : Andrew Davis
Download or read book The Handbook of Medicinal Chemistry written by Andrew Davis and published by Royal Society of Chemistry. This book was released on 2015-07-07 with total page 753 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With chapters covering a wide range of topics from drug discovery processes and optimization, development of synthetic routes, pharmaceutical properties and computational biology, the handbook aims to enable medicinal chemists to apply their academic understanding to every aspect of drug discovery. Each chapter includes expert advice to not only provide a rigorous understanding of the principles being discussed, but to provide useful hints and tips gained from within the pharmaceutical industry. This expertise, combined with project case studies, highlighting and discussing all areas of successful projects, make this an essential handbook for all those involved in pharmaceutical development.
Book Synopsis The Practice of Medicinal Chemistry by : Camille Georges Wermuth
Download or read book The Practice of Medicinal Chemistry written by Camille Georges Wermuth and published by Elsevier. This book was released on 2015-07-01 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research An image bank is available for instructors at www.textbooks.elsevier.com
Book Synopsis Medicinal Chemistry by : Frank D. King
Download or read book Medicinal Chemistry written by Frank D. King and published by . This book was released on 2002 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an valuable introduction to medicinal chemistry for new graduates and PhDs. It will also serve to update more experienced scientists on the newer technologies in the field.
Book Synopsis Chemometric Methods in Molecular Design by : Han van de Waterbeemd
Download or read book Chemometric Methods in Molecular Design written by Han van de Waterbeemd and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: The statistical analysis of experimental and theoretical data lies at the heart of modern drug design. This practice-oriented handbook is a comprehensive account of modern chemometric methods in molecular design. It presents strategies for making more rational choices in the planning of syntheses, and describes techniques for analyzing biological and chemical data. Written by the world's experts, it provides in-depth information on * molecular concepts * experimental design in the planning of syntheses * multivariate analysis of chemical and biological data * statistical validation of QSAR results An additional benefit: the book contains a critical survey of commercially available software packages both for statistical analysis as well as for special applications. Industrial and academic researches in medicinal chemistry and organic chemistry will value this book as a useful source of information for their daily work. Also available: Advanced Computer-Assisted Techniques in Drug Discovery, edited by H. van de Waterbeemd
Book Synopsis Medicinal Chemistry by : Thomas Nogrady
Download or read book Medicinal Chemistry written by Thomas Nogrady and published by Oxford University Press. This book was released on 2005-08-11 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.
Book Synopsis Principles of Organic Medicinal Chemistry by : Rama Rao Nadendla
Download or read book Principles of Organic Medicinal Chemistry written by Rama Rao Nadendla and published by New Age International. This book was released on 2007 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Book Principles Of Organic Medicinal Chemistry Describes The Principles And Concepts Of Chemistry, Synthetic Schemes, Structure Activity Relationships, Mechanism Of Action And Clinical Uses Of Carbon Compounds In The Light Of Modern Trends. The Book Covers The Syllabai Of B. Pharmacy And M.Pharmacy Courses Of All Indian Universities.This Book Comprises Of 22 Chapters. Chapter 1 Gives An Introduction To Medicinal Chemistry, Chapter 2 Explain About The Basics On Principles Of Drug Action And Physicochemical Properties Of Organic Medicinal, Substances Are Elaborated In Chapter 3. The Concepts Of Prodrugs And Drug Metabolism Are Summarized In Chapter 4 And Chapter 5 Respectively. Chapter 6 To Chapter 22 Explains Chemistry, Properties, Mechanism Of Action, Structure Activity Relationships, Chemistry Of Newer Drugs And Clinical Uses Of Various Therapeutic Agents. At The End Of Book, A Set Of More Than 200 Essays And Short Questions And 225 Objective Questions With Answers Are St Strategically Designed.
Book Synopsis Foye's Principles of Medicinal Chemistry by : Thomas L. Lemke
Download or read book Foye's Principles of Medicinal Chemistry written by Thomas L. Lemke and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 1406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Sixth Edition of this well-known text has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. Emphasis is on patient-focused pharmaceutical care and on the pharmacist as a therapeutic consultant, rather than a chemist. A new disease state management section explains appropriate therapeutic options for asthma, chronic obstructive pulmonary disease, and men's and women's health problems. Also new to this edition: Clinical Significance boxes, Drug Lists at the beginning of appropriate chapters, and an eight-page color insert with detailed illustrations of drug structures. Case studies from previous editions and answers to this edition's case studies are available online at thePoint.
Book Synopsis An Introduction to Medicinal Chemistry by : Graham L. Patrick
Download or read book An Introduction to Medicinal Chemistry written by Graham L. Patrick and published by Oxford University Press. This book was released on 2013-01-10 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an introduction to medicinal chemistry. It covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug.
Book Synopsis Microwaves in Organic and Medicinal Chemistry by : C. Oliver Kappe
Download or read book Microwaves in Organic and Medicinal Chemistry written by C. Oliver Kappe and published by John Wiley & Sons. This book was released on 2006-05-12 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors of this guide are experts on the use of microwaves for drug synthesis as well as having much experience in teaching courses held under the auspices of the American Chemical Society and the IUPAC. In this handy source of information for any practicing synthetic chemist they focus on common reaction types in medicinal chemistry, including solid-phase and combinatorial methods. They consider the underlying theory, latest developments in microwave applications and include a variety of examples from recent literature, as well as less common applications that are equally relevant for organic and medicinal chemists. An indispensable reference for researchers with an affinity to modern methods.
Book Synopsis Drug Selectivity by : Norbert Handler
Download or read book Drug Selectivity written by Norbert Handler and published by John Wiley & Sons. This book was released on 2018-02-27 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book "Drug Selectivity - An Evolving Concept in Medicinal Chemistry" provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist.
