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Author : Mukesh Doble
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (12 download)
Download or read book Principles of Downstream Techniques in Biological and Chemical Processes written by Mukesh Doble and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mukesh Doble
Publisher : CRC Press
ISBN 13 : 149873250X
Total Pages : 226 pages
Book Rating : 4.4/5 (987 download)
Download or read book Principles of Downstream Techniques in Biological and Chemical Processes written by Mukesh Doble and published by CRC Press. This book was released on 2016-01-05 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Downstream processing is an essential practice in the production and purification of biosynthethic materials, which is especially important in the production of pharmaceutical products. This book covers the fundamentals and the design concepts of various downstream recovery and purification steps (unit operations) involved in biochemical and chemic
Author : Pau Loke Show
Publisher : CRC Press
ISBN 13 : 0429882513
Total Pages : 186 pages
Book Rating : 4.4/5 (298 download)
Download or read book Bioprocess Engineering written by Pau Loke Show and published by CRC Press. This book was released on 2019-06-13 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioprocess Engineering: Downstream Processing is the first book to present the principles of bioprocess engineering, focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology and explain process analysis from an engineering point of view, using worked examples related to biological systems. This book introduces the commonly used technologies for downstream processing of biobased products. The covered topics include centrifugation, filtration, membrane separation, reverse osmosis, chromatography, biosorption, liquid-liquid separation, and drying. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and design are emphasized. This book is aimed at bioprocess engineers and professionals who wish to perform downstream processing for their feedstock, as well as students.
Author : E. Goldberg
Publisher : Springer Science & Business Media
ISBN 13 : 9400915632
Total Pages : 745 pages
Book Rating : 4.4/5 (9 download)
Download or read book Handbook of Downstream Processing written by E. Goldberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last two decades have seen a phenomenal growth of the field of genetic or biochemical engineering and have witnessed the development and ultimately marketing of a variety of products-typically through the manipulation and growth of different types of microorganisms, followed by the recovery and purification of the associated products. The engineers and biotechnologists who are involved in the full-scale process design of such facilities must be familiar with the variety of unit operations and equipment and the applicable regulatory requirements. This book describes current commercial practice and will be useful to those engineers working in this field in the design, construction and operation of pharmaceutical and biotechnology plants. It will be of help to the chemical or pharmaceutical engineer who is developing a plant design and who faces issues such as: Should the process be batch or continuous or a combination of batch and continuous? How should the optimum process design be developed? Should one employ a new revolutionary separation which could be potentially difficult to validate or use accepted technology which involves less risk? Should the process be run with ingredients formulated from water for injection, deionized water, or even filtered tap water? Should any of the separations be run in cold rooms or in glycol jacketed lines to minimize microbial growth where sterilization is not possible? Should the process equipment and lines be designed to be sterilized in-place, cleaned-in-place, or should every piece be broken down, cleaned and autoclaved after every turn?
Author : Jean-François Hamel
Publisher : Washington, D.C. : American Chemical Society
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.:/5 (44 download)
Download or read book Downstream Processing and Bioseparation written by Jean-François Hamel and published by Washington, D.C. : American Chemical Society. This book was released on 1990 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume examines the state of the art of several important separation processes as they relate to biotechnology. Focusing on isolation and purification of downstream processing, it presents recent research results of several promising techniques. Its 15 chapters cover extraction and membrane processing, processes using biospecific interaction with proteins, and novel isolation and purification processes. Many of the chapters contain data that have not been published before. This volume presents the spectrum of current thinking and activities on bioseparation, specifically of large molecules such as proteins and polysaccharides.
Author : Venko N. Beschkov
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110574004
Total Pages : 211 pages
Book Rating : 4.1/5 (15 download)
Download or read book Downstream Processing in Biotechnology written by Venko N. Beschkov and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-06-21 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current book gives an excellent insight into downstream processing technology and explains how to establish a successful strategy for an efficient recovery, isolation and purification of biosynthetic products. In addition to the overview of purification steps and unit operations, the authors provide practical information on capital and operating costs related to downstream processing.
Author : B. SIVASANKAR
Publisher : PHI Learning Pvt. Ltd.
ISBN 13 : 8120326490
Total Pages : 279 pages
Book Rating : 4.1/5 (23 download)
Download or read book BIOSPERATIONS written by B. SIVASANKAR and published by PHI Learning Pvt. Ltd.. This book was released on 2005-01-01 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This systematically organized and well-balanced book compresses within the covers of a single volume the theoretical principles and techniques involved in bio-separations, also called downstream processing. These techniques are derived from a range of subjects, for example, physical chemistry, analytical chemistry, bio-chemistry, biological science and chemical engineering. Organized in its 15 chapters, the text covers in the first few chapters topics related to chemical engineering unit operations such as filtration, centrifugation, adsorption, extraction and membrane separation as applied to bioseparations. The use of chromatography as practiced at laboratory as well as industrial scale operation and related techniques such as gel filtration, affinity and pseudoaffinity chromatography, ion-exchange chromatography, electrophoresis and related methods have been discussed. The important applications of these techniques have also been highlighted.
Author : SYED TANVEER AHMED INAMDAR
Publisher : PHI Learning Pvt. Ltd.
ISBN 13 : 8120345851
Total Pages : 463 pages
Book Rating : 4.1/5 (23 download)
Download or read book BIOCHEMICAL ENGINEERING written by SYED TANVEER AHMED INAMDAR and published by PHI Learning Pvt. Ltd.. This book was released on 2012-09-05 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book, now in its Third Edition, continues to offer the basic concepts and principles of biochemical engineering. It covers the curriculum for a first-course in Biochemical Engineering at the undergraduate level of Chemical Engineering discipline and also caters to the requirements of BTech Biotechnology and BSc Biotechnology offered by various universities. The text first explains the basics of microbiology and biochemistry before moving on to explore the significance of enzymes, their properties, types, kinetics, industrial applications, production and formulation and the methods of their immobilization. It also deals with cell growth and its kinetic aspects and discusses various types of biological reactors with an emphasis on key engineering practices related to fermentation processes and products, bioreactor design and operation. It offers a complete description on downstream processing and control of microorganisms. Besides, it also covers in the appendices some important topics such as process kinetics and reactor analysis, bioenergetics, and environmental microbiology to justify their relevance in biochemical engineering. NEW TO THIS EDITION : Offers a complete description with applications and configurations of membrane bioreactors (Chapter 7). Presents a facelift of downstream processes in the topics, viz. disruption of cells supported with flow sheet, freeze drying, formulation, etc. along with a total revamping of the discussion on supercritical fluid extraction and induction of biofouling (Chapter 9). Provides a new appendix—Appendix D—on Self-Assessment Exercises, which incorporates questions in the form of multiple choice, true/false and fill in the blanks in order to assess the level of understanding.
Author : Maria Rajkiewicz
Publisher : CRC Press
ISBN 13 : 1498702333
Total Pages : 359 pages
Book Rating : 4.4/5 (987 download)
Download or read book Chemical and Applied Engineering Materials written by Maria Rajkiewicz and published by CRC Press. This book was released on 2015-05-27 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new research book explores and discusses a range of topics on the physical and mechanical properties of chemical engineering materials. Chapters from prominent researchers in the fields of physics, chemistry, and engineering science present new research on composite materials, blends, carbon nanotubes, and nanocomposites along with their appli
Author : Seid Mahdi Jafari
Publisher : Springer Nature
ISBN 13 : 3030846431
Total Pages : 479 pages
Book Rating : 4.0/5 (38 download)
Download or read book Membrane Separation of Food Bioactive Ingredients written by Seid Mahdi Jafari and published by Springer Nature. This book was released on 2022-03-11 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers current developments in membrane-based technologies for the successful recovery of food bioactive ingredients and molecules. Chapters explore emerging technologies, such as microfiltration, ultrafiltration, nanofiltration, and membrane distillation, for the selective concentration and food ingredients from food by-products, as well as techniques, such as pervaporation, for the selective separation and recovery of aroma compounds. The text provides one of the first examinations of other membrane-based technologies, such as liquid membranes (microemulsions), membrane distillation (MD) and pervaporation (PV), as thermal driven membrane processes. The separation of metabolites from microalgae and fermentation broths using membrane technologies is also covered. Researchers in food science, pharmaceutics and biotechnology looking to stay up-to-date on bioactive recovery, as well as membranologists exploring new applications for membrane-based technologies, will find this text a useful resource.
Author : Sarfaraz K. Niazi
Publisher : CRC Press
ISBN 13 : 1466585749
Total Pages : 746 pages
Book Rating : 4.4/5 (665 download)
Download or read book Fundamentals of Modern Bioprocessing written by Sarfaraz K. Niazi and published by CRC Press. This book was released on 2017-07-27 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological drug and vaccine manufacturing has quickly become one of the highest-value fields of bioprocess engineering, and many bioprocess engineers are now finding job opportunities that have traditionally gone to chemical engineers. Fundamentals of Modern Bioprocessing addresses this growing demand. Written by experts well-established in the field, this book connects the principles and applications of bioprocessing engineering to healthcare product manufacturing and expands on areas of opportunity for qualified bioprocess engineers and students. The book is divided into two sections: the first half centers on the engineering fundamentals of bioprocessing; while the second half serves as a handbook offering advice and practical applications. Focused on the fundamental principles at the core of this discipline, this work outlines every facet of design, component selection, and regulatory concerns. It discusses the purpose of bioprocessing (to produce products suitable for human use), describes the manufacturing technologies related to bioprocessing, and explores the rapid expansion of bioprocess engineering applications relevant to health care product manufacturing. It also considers the future of bioprocessing—the use of disposable components (which is the fastest growing area in the field of bioprocessing) to replace traditional stainless steel. In addition, this text: Discusses the many types of genetically modified organisms Outlines laboratory techniques Includes the most recent developments Serves as a reference and contains an extensive bibliography Emphasizes biological manufacturing using recombinant processing, which begins with creating a genetically modified organism using recombinant techniques Fundamentals of Modern Bioprocessing outlines both the principles and applications of bioprocessing engineering related to healthcare product manufacturing. It lays out the basic concepts, definitions, methods and applications of bioprocessing. A single volume comprehensive reference developed to meet the needs of students with a bioprocessing background; it can also be used as a source for professionals in the field.
Author : Springer
Publisher : Springer
ISBN 13 : 9783662153277
Total Pages : 224 pages
Book Rating : 4.1/5 (532 download)
Download or read book Downstream Processing written by Springer and published by Springer. This book was released on 2014-01-15 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Pauline M. Doran
Publisher : Elsevier
ISBN 13 : 0080528120
Total Pages : 455 pages
Book Rating : 4.0/5 (85 download)
Download or read book Bioprocess Engineering Principles written by Pauline M. Doran and published by Elsevier. This book was released on 1995-04-03 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists. This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems. * * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists * Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems * Comprehensive, single-authored * 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems * 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors * Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading * Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used * Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels.
Author : M. S. Verrall
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 384 pages
Book Rating : 4.3/5 (91 download)
Download or read book Downstream Processing of Natural Products written by M. S. Verrall and published by John Wiley & Sons. This book was released on 1996-08-06 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products, broadly defined as high value chemical entities derived from plants or microbial sources, have been known and exploited for many years. In recent years, as the need for higher potency and predictability of such products has increased, more sophisticated concentration and isolation procedures have been developed. With the passage of time, such procedures have been rationalized in terms of scientific principles but, in general, theory has followed behind practice, leading at any given time to an absence from the literature of methods which are truly state of the art. Downstream Processing of Natural Products: A Practical Handbook is a highly practical manual which addresses this issue, and guides researchers and industrial workers through the many potential pitfalls of natural product isolation. The contributors to this volume, all of whom have wide practical experience in this field, present state-of-the-art techniques and observations. The three main stages of natural product purification are covered, namely product release, capture, and purification, and both proteins and secondary metabolites are covered. There is special mention of the requirements of the regulatory authorities with respect to Good Manufacturing Practice, and practical guidance is given on scale-up procedures and process scale instrumentation. Downstream Processing of Natural Products: A Practical Handbook will provide essential practical guidance to all those involved in natural product isolation. This includes academic and industrial researchers, postgraduate students and technicians working in the biotechnology field.
Author : Paul A. Belter
Publisher : Wiley-Interscience
ISBN 13 : 9780471121138
Total Pages : 0 pages
Book Rating : 4.1/5 (211 download)
Download or read book Bioseparations Downstream Processing for Biotechnology written by Paul A. Belter and published by Wiley-Interscience. This book was released on 1994-10-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a concise introduction to the separation and purification of biochemicals. Bridges two scientific cultures, providing an introduction to bioseparations for scientists with no background in engineering and for engineers with little grounding in biology. The authors supplement the ideas by simple worked examples, making the techniques of bioseparations easy to learn. Discusses removal of insolubles, product isolation, purification and polishing.
Author :
Publisher : Springer
ISBN 13 : 9783540120964
Total Pages : 212 pages
Book Rating : 4.1/5 (29 download)
Download or read book Downstream Processing written by and published by Springer. This book was released on 1983-03-01 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Karl Schügerl
Publisher : Springer Science & Business Media
ISBN 13 : 3662030640
Total Pages : 221 pages
Book Rating : 4.6/5 (62 download)
Download or read book Solvent Extraction in Biotechnology written by Karl Schügerl and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solvent Extraction in Biotechnology deals with the reco- very and purification of primary and secondary metabolites by solvent extraction. In the first part the reaction engineering principles: definitions, thermodynamic fundamentals, and system models, the kinetics of mass transfer between two phases without and with chemical reaction as well as extraction equipment, which are important for downstream processing in biotechnology, are considered in detail. The special part of the book describes the recovery of low-molecular metabolites: alcohols, acids and antibiotics with organic solvents, carrier-modifier-solvent systems, supercritical gases as well as with liquid membrane techniques. Several practical examples are given for the recovery of different metabolites as well as for the calculation of the extraction processes necessary for equipment design. Besides solvent extraction, novel separation techniques with liquid membrane, microemulsion and reversed micelles are also presented. This book will introduce the biochemical engineer and process engineer to the recovery of products from complex cultivation broths by modern techniques of solvent extraction and help them with process design.
