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Author :
Publisher :
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.:/5 (6 download)
Download or read book Primates and Human Cancer written by and published by . This book was released on 1979 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 72 pages
Book Rating : 4.3/5 (129 download)
Download or read book Cancer in Subhuman Primates written by and published by . This book was released on 1962 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kurt Benirschke
Publisher : Springer Science & Business Media
ISBN 13 : 146124918X
Total Pages : 1027 pages
Book Rating : 4.4/5 (612 download)
Download or read book Primates written by Kurt Benirschke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: This conference represents the first time in my life when I felt it was a misfor tune, rather than a major cause of my happiness, that I do conservation work in New Guinea. Yes, it is true that New Guinea is a fascinating microcosm, it has fascinating birds and people, and it has large expanses of undisturbed rainforest. In the course of my work there, helping the Indonesian government and World Wildlife Fund set up a comprehensive national park system, I have been able to study animals in areas without any human population. But New Guinea has one serious drawback: it has no primates, except for humans. Thus, I come to this conference on primate conservation as an underprivileged and emotionally deprived observer, rather than as an involved participant. Nevertheless, it is easy for anyone to become interested in primate conserva tion. The public cares about primates. More specifically, to state things more realistically, many people care some of the time about some primates. Primates are rivaled only by birds, pandas, and the big cats in their public appeal. For some other groups of animals, the best we can say is that few people care about them, infrequently. For most groups of animals, no one cares about them, ever.
Author : Committee on Long-Term Care of Chimpanzees
Publisher : National Academies Press
ISBN 13 : 0309591155
Total Pages : 108 pages
Book Rating : 4.3/5 (95 download)
Download or read book Chimpanzees in Research written by Committee on Long-Term Care of Chimpanzees and published by National Academies Press. This book was released on 1997-09-01 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chimpanzees in biomedical and behavioral research constitute a national resource that has been valuable in addressing national health needs. Facilities that house chimpanzees owned and supported by the National Institutes of Health (NIH) have successfully met the research requirements of the scientific community. The captive chimpanzee population in the United States has grown substantially, particularly over the last decade. That growth is due primarily to the success of the NIH-sponsored Chimpanzee Breeding and Research Program, which achieved the birth numbers thought necessary to meet the projected needs of biomedical research. However, the expected level of use of the chimpanzee model in biomedical research did not materialize, and that has created a complex problem that threatens both the availability of chimpanzees for research in the future and the infrastructure required to ensure the well-being of captive chimpanzees used in biomedical research. Because the present system is fragmented, it is impossible to formulate an accurate overview of the size and nature of the chimpanzee population. But, if the chimpanzee is to continue to be used in biomedical research responsibly, effectively, and cost-effectively, we must be able to oversee, track, and coordinate the maintenance and use of chimpanzees and to control the size of the population. To assess the long-range situation and to develop, implement, and monitor the application of policies for the proper use and care of chimpanzees, an authoritative, centralized oversight structure is imperative. Once it is in place, it will be possible to refine and implement this report's recommendations.
Author : Geoffrey H. Bourne
Publisher : Academic Press
ISBN 13 : 1483258041
Total Pages : 554 pages
Book Rating : 4.4/5 (832 download)
Download or read book Nonhuman Primates and Medical Research written by Geoffrey H. Bourne and published by Academic Press. This book was released on 2014-05-10 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonhuman Primates and Medical Research focuses on the contributions of nonhuman primates to biomedical research. The selection first elaborates on monkeys and yellow fever, cell cultures, and tuberculosis and bacterial infection. Discussions focus on bacterial diseases, tuberculosis, radiobiology, antibody formation and pharmacologic studies, cell-culture media and methods, the rhesus monkey and early history of yellow fever research, and monkeys and yellow fever in the future. The text then elaborates on virus research, models for investigation in parasitology, and primates as organ donors in transplantation studies in man. The manuscript examines the importance of monkeys for the study of malignant tumors in man; use of primates in cardiovascular research; and humanlike diseases in anthropoid apes. Topics include etiology of humanlike disease in anthropoid apes, atherosclerosis, historical aspects of primate research, selection of a suitable primate, and preeclampsia. The text also ponders on primate studies and human evolution and mental retardation. The selection is a valuable reference for researchers interested in the contributions of nonhuman primates to biomedical research.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309220394
Total Pages : 200 pages
Book Rating : 4.3/5 (92 download)
Download or read book Chimpanzees in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2012-01-05 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.
Author : Debbie Bookchin
Publisher : Macmillan + ORM
ISBN 13 : 1466848995
Total Pages : 539 pages
Book Rating : 4.4/5 (668 download)
Download or read book The Virus and the Vaccine written by Debbie Bookchin and published by Macmillan + ORM. This book was released on 2013-07-02 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jonas Salk's polio vaccine has taken on an almost legendary quality as a medical miracle, for it largely eradicated one of the most feared diseases of the 20th century. But the story of the vaccine has a dark side, one that has never been fully told before... Between 1954 and 1963, close to 98 million Americans received polio vaccinations contaminated with a carcinogenic monkey virus, now known as SV40. A concerted government effort downplayed the incident, and it was generally accepted that although oncogenic to laboratory animals, SV40 was harmless to humans. But now SV40 in showing up in human cancers, and prominent researchers are demanding a serious public health response to this forgotten polio vaccine contaminant. A gripping medical detective story, The Virus and the Vaccine raises major questions about vaccine policy.
Author :
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)
Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309038391
Total Pages : 113 pages
Book Rating : 4.3/5 (9 download)
Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Author : Beata Ujvari
Publisher : Academic Press
ISBN 13 : 0128043806
Total Pages : 290 pages
Book Rating : 4.1/5 (28 download)
Download or read book Ecology and Evolution of Cancer written by Beata Ujvari and published by Academic Press. This book was released on 2017-02-08 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures. Covers all aspects of the evolution of cancer, appealing to researchers seeking to understand its origins and effects of treatments on its progression, as well as to lecturers in evolutionary medicine Functions as both an introduction to cancer and evolution and a review of the current research on this burgeoning, exciting field, presented by an international group of leading editors and contributors Improves understanding of the origin and the evolution of cancer, aiding efforts to determine how this disease interferes with biotic interactions that govern ecosystems Highlights research that intends to apply evolutionary principles to help predict emergence and metastatic progression with the aim of improving therapies
Author : Charles Swanton
Publisher : Perspectives Cshl
ISBN 13 : 9781621821434
Total Pages : 350 pages
Book Rating : 4.8/5 (214 download)
Download or read book Cancer Evolution written by Charles Swanton and published by Perspectives Cshl. This book was released on 2017 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer.
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309086108
Total Pages : 118 pages
Book Rating : 4.3/5 (9 download)
Download or read book Immunization Safety Review written by Institute of Medicine and published by National Academies Press. This book was released on 2003-12-26 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.
Author : Timothy A. Kohler
Publisher : Oxford University Press, USA
ISBN 13 : 0195131681
Total Pages : 413 pages
Book Rating : 4.1/5 (951 download)
Download or read book Dynamics in Human and Primate Societies written by Timothy A. Kohler and published by Oxford University Press, USA. This book was released on 2000 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an emphasis on small-scale societies in an effort to maximize realism in the modeling efforts applied to social evolution, this volume is an important step toward an actor-oriented, cross-disciplinary approach to understanding human behavior over time.".
Author : Christian R. Abee
Publisher : Academic Press
ISBN 13 : 0123978386
Total Pages : 868 pages
Book Rating : 4.1/5 (239 download)
Download or read book Nonhuman Primates in Biomedical Research written by Christian R. Abee and published by Academic Press. This book was released on 2012-06-07 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in bioledical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information Includes four color images throughout
Author : Harald zur Hausen
Publisher : John Wiley & Sons
ISBN 13 : 3527609296
Total Pages : 531 pages
Book Rating : 4.5/5 (276 download)
Download or read book Infections Causing Human Cancer written by Harald zur Hausen and published by John Wiley & Sons. This book was released on 2007-09-24 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infections must be thought as one of the most important, if not the most important, risk factors for cancer development in humans. Approximately 15-20% of all cases of cancer around the world are caused by viruses. The establishment of a causal relationship between the presence of specific infective agents and certain types of human cancer represents a key step in the development of novel therapeutic and preventive strategies. In this book, Professor zur Hausen (Nobel Prize in Physiology/Medicine 2008) provides a thorough and comprehensive overview on carcinogenic infective agents -- viruses, bacteria, parasites and protozoons -- as well as their corresponding transforming capacities and mechanisms. The result is an invaluable and instructive reference for all oncologists, microbiologists and molecular biologists working in the area of infections and cancer. The author was among the first scientists to reveal the cervical cancer-inducing mechanisms of human papilloma viruses and isolated HPV16 and HPV18, and, as early as 1976, published the hypothesis that wart viruses play a role in the development of this type of cancer.
Author : Robert M. Sapolsky
Publisher : Simon and Schuster
ISBN 13 : 1416590366
Total Pages : 310 pages
Book Rating : 4.4/5 (165 download)
Download or read book A Primate's Memoir written by Robert M. Sapolsky and published by Simon and Schuster. This book was released on 2007-11-01 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the tradition of Jane Goodall and Dian Fossey, Robert Sapolsky, a foremost science writer and recipient of a MacArthur Genius Grant, tells the mesmerizing story of his twenty-one years in remote Kenya with a troop of savanna baboons. "I had never planned to become a savanna baboon when I grew up; instead, I had always assumed I would become a mountain gorilla,” writes Robert Sapolsky in this witty and riveting chronicle of a scientist’s coming-of-age in Africa. An exhilarating account of Sapolsky’s twenty-one-year study of a troop of rambunctious baboons in Kenya, A Primate’s Memoir interweaves serious scientific observations with wry commentary about the challenges and pleasures of living in the wilds of the Serengeti—for man and beast alike. Over two decades, Sapolsky survives culinary atrocities, gunpoint encounters, and a surreal kidnapping, while witnessing the encroachment of the tourist mentality on Africa. As he conducts unprecedented physiological research on wild primates, he becomes enamored of his subjects—unique and compelling characters in their own right—and he returns to them summer after summer, until tragedy finally prevents him. By turns hilarious and poignant, A Primate’s Memoir is a magnum opus from one of our foremost science writers.
Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher : IARC
ISBN 13 : 9789283212836
Total Pages : 1476 pages
Book Rating : 4.2/5 (128 download)
Download or read book Tobacco Smoke and Involuntary Smoking written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC. This book was released on 2004 with total page 1476 pages. Available in PDF, EPUB and Kindle. Book excerpt: The IARC Monographs series publishes authoritative independent assessments by international experts of the carcinogenic risks posed to humans by a variety of agents, mixtures and exposures. They are a resource of information for both researchers and national and international authorities. This volume is particularly significant because tobacco smoke not only causes more deaths from cancer than any other known agent; it also causes more deaths from vascular and respiratory diseases. This volume contains all the relevant information on both direct and passive smoking. It is organised by first looking at the nature of agent before collecting the evidence of cancer in humans. This is followed by carcinogenicity studies on animals and then any other data relevant to an evaluation.
