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Pretty Palynziq
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Download or read book Pretty Palynziq written by Jane Kenney and published by . This book was released on 2021-11-29 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phenylketonuria (PKU) affects 1 in 10,000 to 15,000 newborns each year. There is no cure as of writing this book, only treatments. Palynziq is one of them. In a series of journal entries, Jane Kenney embarks on a new chapter in her life documenting the entire process of being on the new drug Palynziq, nasty side effects and all. She also includes insight and educational information on PKU and what it's really like to live as a PKU'er.
Book Synopsis The Challenge of CMC Regulatory Compliance for Biopharmaceuticals by : John Geigert
Download or read book The Challenge of CMC Regulatory Compliance for Biopharmaceuticals written by John Geigert and published by Springer. This book was released on 2019-05-08 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopharmaceuticals (i.e., biological medicines sourced from genetically-engineered living systems) for treatment of human diseases have become a significant percentage of the pharmaceutical industry. And not just the recombinant DNA-derived proteins and monoclonal antibodies (both from the innovators and biosimilars); but now, an increasing awareness of the importance of gene therapy and genetically engineered cellular medicinal products. These biopharmaceuticals are being developed by many companies whose Chemistry, Manufacturing & Control (CMC) teams have varying degrees of familiarity or experience with the CMC strategy and regulatory compliance requirements for these challenging products. Companies clearly plan out the strategy for their clinical study plans, but frequently, the development of a strategy for CMC is an afterthought. Coupled with the complexity of the biopharmaceutical manufacturing processes and products, and this can be a recipe for disaster. The third edition of this book provides insights and practical guidance for the CMC teams to develop an acceptable cost-effective, risk-based CMC regulatory compliance strategy for all biopharmaceuticals (recombinant proteins, monoclonal antibodies, genetically engineered viruses and genetically engineered human cells) from early clinical stage development through market approval. The third edition of this book provides added coverage for the biosimilars, antibody drug conjugates (ADCs), bispecific antibodies, genetically engineered viruses, and genetically engineered cells. This third edition of the book also addresses the heightened pressure on CMC regulatory compliance timelines due to the introduction of expedited clinical pathways moving the clinical development closer to a seamless phase process (e.g., FDA Breakthrough Therapy designation, CBER Regenerative Medicine Advanced Therapy (RMAT) designation, EMA Priority Medicines (PRIME) designation). The Challenge of CMC Regulatory Compliance for Biopharmaceuticals is essential, practical information for all pharmaceutical development scientists, Manufacturing and Quality Unit staff, Regulatory Affairs personnel, and senior management involved in the manufacture of biopharmaceuticals.
Book Synopsis The Folly of Fools by : Robert Trivers
Download or read book The Folly of Fools written by Robert Trivers and published by Basic Books (AZ). This book was released on 2011-10-25 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores the author's theorized evolutionary basis for self-deception, which he says is tied to group conflict, courtship, neurophysiology, and immunology, but can be negated by awareness of it and its results.
Book Synopsis Deceit and Self-Deception by : Robert Trivers
Download or read book Deceit and Self-Deception written by Robert Trivers and published by Penguin Books. This book was released on 2014-01-30 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: We lie to ourselves every day: about how well we drive, how much we're enjoying ourselves - even how good looking we are. In this ground-breaking book, Robert Trivers examines not only how we self-deceive, but also why, taking fascinating examples from aviation disasters, con artists, sexual betrayals and conflicts within families. Revealing, provocative and witty, Deceit and Self-Deception is one of the most vital books written this century, and will make you rethink everything that you think you know. 'Original and important . . . remarkable, thick with ideas.' Financial Times 'One of the great thinkers in the history of Western thought.' Steven Pinker 'A swift tour of links between deception and evolutionary progress . . . fascinating.' Economist 'I devoured it from cover to cover . . . exhilarating.' Guardian 'A powerful book . . . essential for anyone who wants to try to counter their own unconscious biases.' Independent
Book Synopsis Medical and Dental Support by : United States. Marine Corps
Download or read book Medical and Dental Support written by United States. Marine Corps and published by . This book was released on 1963 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis It's More Than Money by : Patricia Annino
Download or read book It's More Than Money written by Patricia Annino and published by CreateSpace. This book was released on 2014-04-09 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's More Than Money: Protect Your Legacy Is each generation of your family aware of the "family brand" - the foundational values you want them all to share? Have you discussed the objectives- in business or philanthropy or investments or family activities- that will translate these values into a family plan? Do you have the enabling structure (legal estate planning and business documents, financial investments and team of advisors) in place to carry out the plan? Most families cannot answer "yes" to all these questions. Directed at the "Captain of the Ship" the head of the family, but written in a way that is accessible to all interested family members, Its' More than Money explains how to: * Focus on what your values are. *Align those values with your goals. *Work with your team of advisors to put in place the legal documents and financial framework that wil.. *Protect you, yoru family, your charities and your legacy. This is both a how to do it blueprint and a handbook designed to provoke family discussion, understanding and unity.
Download or read book Quilts & Afghans written by and published by . This book was released on 1984 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Elephant in the Brain by : Kevin Simler
Download or read book The Elephant in the Brain written by Kevin Simler and published by Oxford University Press. This book was released on 2018 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human beings are primates, and primates are political animals. Our brains, therefore, are designed not just to hunt and gather, but also to help us get ahead socially, often via deception and self-deception. But while we may be self-interested schemers, we benefit by pretending otherwise. The less we know about our own ugly motives, the better - and thus we don't like to talk or even think about the extent of our selfishness. This is "the elephant in the brain." Such an introspective taboo makes it hard for us to think clearly about our nature and the explanations for our behavior. The aim of this book, then, is to confront our hidden motives directly - to track down the darker, unexamined corners of our psyches and blast them with floodlights. Then, once everything is clearly visible, we can work to better understand ourselves: Why do we laugh? Why are artists sexy? Why do we brag about travel? Why do we prefer to speak rather than listen? Our unconscious motives drive more than just our private behavior; they also infect our venerated social institutions such as Art, School, Charity, Medicine, Politics, and Religion. In fact, these institutions are in many ways designed to accommodate our hidden motives, to serve covert agendas alongside their "official" ones. The existence of big hidden motives can upend the usual political debates, leading one to question the legitimacy of these social institutions, and of standard policies designed to favor or discourage them. You won't see yourself - or the world - the same after confronting the elephant in the brain.
Book Synopsis Why Everyone (Else) Is a Hypocrite by : Robert Kurzban
Download or read book Why Everyone (Else) Is a Hypocrite written by Robert Kurzban and published by Princeton University Press. This book was released on 2012-05-27 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evolutionary psychology behind human inconsistency We're all hypocrites. Why? Hypocrisy is the natural state of the human mind. Robert Kurzban shows us that the key to understanding our behavioral inconsistencies lies in understanding the mind's design. The human mind consists of many specialized units designed by the process of evolution by natural selection. While these modules sometimes work together seamlessly, they don't always, resulting in impossibly contradictory beliefs, vacillations between patience and impulsiveness, violations of our supposed moral principles, and overinflated views of ourselves. This modular, evolutionary psychological view of the mind undermines deeply held intuitions about ourselves, as well as a range of scientific theories that require a "self" with consistent beliefs and preferences. Modularity suggests that there is no "I." Instead, each of us is a contentious "we"--a collection of discrete but interacting systems whose constant conflicts shape our interactions with one another and our experience of the world. In clear language, full of wit and rich in examples, Kurzban explains the roots and implications of our inconsistent minds, and why it is perfectly natural to believe that everyone else is a hypocrite.
Download or read book The Scout Mindset written by Julia Galef and published by Penguin. This book was released on 2021-04-13 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: "...an engaging and enlightening account from which we all can benefit."—The Wall Street Journal A better way to combat knee-jerk biases and make smarter decisions, from Julia Galef, the acclaimed expert on rational decision-making. When it comes to what we believe, humans see what they want to see. In other words, we have what Julia Galef calls a "soldier" mindset. From tribalism and wishful thinking, to rationalizing in our personal lives and everything in between, we are driven to defend the ideas we most want to believe—and shoot down those we don't. But if we want to get things right more often, argues Galef, we should train ourselves to have a "scout" mindset. Unlike the soldier, a scout's goal isn't to defend one side over the other. It's to go out, survey the territory, and come back with as accurate a map as possible. Regardless of what they hope to be the case, above all, the scout wants to know what's actually true. In The Scout Mindset, Galef shows that what makes scouts better at getting things right isn't that they're smarter or more knowledgeable than everyone else. It's a handful of emotional skills, habits, and ways of looking at the world—which anyone can learn. With fascinating examples ranging from how to survive being stranded in the middle of the ocean, to how Jeff Bezos avoids overconfidence, to how superforecasters outperform CIA operatives, to Reddit threads and modern partisan politics, Galef explores why our brains deceive us and what we can do to change the way we think.
Book Synopsis Good Reasons for Bad Feelings by : Randolph M. Nesse, MD
Download or read book Good Reasons for Bad Feelings written by Randolph M. Nesse, MD and published by Penguin. This book was released on 2019-02-12 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: A founder of the field of evolutionary medicine uses his decades of experience as a psychiatrist to provide a much-needed new framework for making sense of mental illness. Why do I feel bad? There is real power in understanding our bad feelings. With his classic Why We Get Sick, Dr. Randolph Nesse helped to establish the field of evolutionary medicine. Now he returns with a book that transforms our understanding of mental disorders by exploring a fundamentally new question. Instead of asking why certain people suffer from mental illness, Nesse asks why natural selection has left us all with fragile minds. Drawing on revealing stories from his own clinical practice and insights from evolutionary biology, Nesse shows how negative emotions are useful in certain situations, yet can become overwhelming. Anxiety protects us from harm in the face of danger, but false alarms are inevitable. Low moods prevent us from wasting effort in pursuit of unreachable goals, but they often escalate into pathological depression. Other mental disorders, such as addiction and anorexia, result from the mismatch between modern environment and our ancient human past. And there are good evolutionary reasons for sexual disorders and for why genes for schizophrenia persist. Taken together, these and many more insights help to explain the pervasiveness of human suffering, and show us new paths for relieving it by understanding individuals as individuals.
Download or read book Lucifer's Legacy written by Frank Close and published by Courier Corporation. This book was released on 2014-01-15 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published: Oxford; New York: Oxford University Press, 2000.
Book Synopsis Naked Economics: Undressing the Dismal Science by : Charles Wheelan
Download or read book Naked Economics: Undressing the Dismal Science written by Charles Wheelan and published by W. W. Norton & Company. This book was released on 2003-09-17 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seeks to provide an engaging and comprehensive primer to economics that explains key concepts without technical jargon and using common-sense examples.
Book Synopsis Subliminal Seduction by : Wilson Bryan Key
Download or read book Subliminal Seduction written by Wilson Bryan Key and published by New Amer Library. This book was released on 1981-01 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the ways in which the media uses sex and violence to manipulate human behavior, citing specific examples from Playboy, Vogue, and Cosmopolitan magazines
Download or read book Post Corona written by Scott Galloway and published by Penguin. This book was released on 2020-11-24 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: New York Times bestseller! "Few are better positioned to illuminate the vagaries of this transformation than Galloway, a tech entrepreneur, author and professor at New York University’s Stern School. In brisk prose and catchy illustrations, he vividly demonstrates how the largest technology companies turned the crisis of the pandemic into the market-share-grabbing opportunity of a lifetime." --The New York Times "As good an analysis as you could wish to read." --The Financial Times From bestselling author and NYU Business School professor Scott Galloway comes a keenly insightful, urgent analysis of who stands to win and who's at risk to lose in a post-pandemic world The COVID-19 outbreak has turned bedrooms into offices, pitted young against old, and widened the gaps between rich and poor, red and blue, the mask wearers and the mask haters. Some businesses--like home exercise company Peloton, video conference software maker Zoom, and Amazon--woke up to find themselves crushed under an avalanche of consumer demand. Others--like the restaurant, travel, hospitality, and live entertainment industries--scrambled to escape obliteration. But as New York Times bestselling author Scott Galloway argues, the pandemic has not been a change agent so much as an accelerant of trends already well underway. In Post Corona, he outlines the contours of the crisis and the opportunities that lie ahead. Some businesses, like the powerful tech monopolies, will thrive as a result of the disruption. Other industries, like higher education, will struggle to maintain a value proposition that no longer makes sense when we can't stand shoulder to shoulder. And the pandemic has accelerated deeper trends in government and society, exposing a widening gap between our vision of America as a land of opportunity, and the troubling realities of our declining wellbeing. Combining his signature humor and brash style with sharp business insights and the occasional dose of righteous anger, Galloway offers both warning and hope in equal measure. As he writes, "Our commonwealth didn't just happen, it was shaped. We chose this path--no trend is permanent and can't be made worse or corrected."
Download or read book Wild Life written by Robert Trivers and published by Biosocial Research. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Robert Trivers is a living legend in biology and the social sciences, a man the Harvard psychologist Steven Pinker calls ''one of the great thinkers in the history of Western thought" and Time magazine named one of the greatest scientists and thinkers of the 20th Century. His theories on the evolutionary tensions between parent and offspring, sibling and sibling, man and woman, friend and friend, and a person and himself or herself have not only revolutionized genetics and evolutionary biology but have influenced disciplines from medicine and the social sciences to history, economics, and literary studies. But unlike other renowned scientists, Trivers has spent time behind bars, drove a getaway car for Huey P. Newton, and founded an armed group in Jamaica to protect gay men from mob violence. Now, in the entertaining tradition of Surely You're Joking Mr. Feynman, Trivers tell us in his inimitable voice about the inimitable life behind the revolutionary science. He comments with irreverent wit and penetrating insight on everything from American racism to the history of psychiatry to who killed Peter Tosh, musical heir to Bob Marley. Sprinkled with anecdotes about such luminaries as Richard Dawkins and Stephen Jay Gould, and with photographs throughout, this volume is sure to enlighten and entertain anyone with an interest in science, the human condition, or the nature of creative genius.
Download or read book The Anatomy of a Fraud written by and published by . This book was released on 1983 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:
