Precision Medicine In Diabetes

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Precision Medicine in Diabetes

Author : Rita Basu
Publisher : Springer Nature
ISBN 13 : 3030989275
Total Pages : 340 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis Precision Medicine in Diabetes by : Rita Basu

Download or read book Precision Medicine in Diabetes written by Rita Basu and published by Springer Nature. This book was released on 2022-05-19 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing clarity to the emerging model of precision medicine within the diabetes field, and expanding upon how it will lead to the development of specifically tailored treatment for patients and even macro strategies in public health, this unique book explores the realm of biomarkers in the era of big data. Various experts in their respective areas discuss the current practice to illuminate how creating a more discreet profile of patients and even substratum of populations will lead to more refined therapies targeted towards the phenotype and genotype of the patient. Embracing a multidisciplinary team science approach, this book demonstrates how precision medicine in diabetes can mine a web of data toward diabetes risk stratification and treatment options. The authors skillfully articulate how the construction of various prediction-based models can revolutionize clinical decision-making, and they examine the challenges and pitfalls of integrating disparate sources of information and how the collection of data and cooperation among stakeholders will be key to the future of precision medicine in diabetes treatment. Topics include personalized approaches to the management of both type 1 and type 2 diabetes, various macro and microvascular complications of diabetes, inpatient management of glycemia, nutrition, exercise, advances in diabetes technology and others. Ideal for clinical endocrinologists and other professionals involved in the management of diabetes and its complications, Precision Medicine in Diabetes is first of its kind to address this paradigm-shifting topic in a comprehensive way.

Toward Precision Medicine

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309222222
Total Pages : 142 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Toward Precision Medicine by : National Research Council

Download or read book Toward Precision Medicine written by National Research Council and published by National Academies Press. This book was released on 2012-01-16 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Precision Medicine in Type 2 Diabetes

Author : J. Dennis
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (11 download)

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Book Synopsis Precision Medicine in Type 2 Diabetes by : J. Dennis

Download or read book Precision Medicine in Type 2 Diabetes written by J. Dennis and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Personalized Predictive Modeling in Type 1 Diabetes

Author : Eleni I. Georga
Publisher : Academic Press
ISBN 13 : 0128051469
Total Pages : 252 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Personalized Predictive Modeling in Type 1 Diabetes by : Eleni I. Georga

Download or read book Personalized Predictive Modeling in Type 1 Diabetes written by Eleni I. Georga and published by Academic Press. This book was released on 2017-12-11 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or multivariate), (ii) regression technique (linear or non-linear), (iii) learning mechanism (batch or sequential), (iv) development and testing procedure and (v) scaling properties. In addition, simulation models of meal-derived glucose absorption and insulin dynamics and kinetics are covered, as an integral part of glucose predictive models. This book will help engineers and clinicians to: select a regression technique which can capture both linear and non-linear dynamics in glucose metabolism in diabetes, and which exhibits good generalization performance under stationary and non-stationary conditions; ensure the scalability of the optimization algorithm (learning mechanism) with respect to the size of the dataset, provided that multiple days of patient monitoring are needed to obtain a reliable predictive model; select a features set which efficiently represents both spatial and temporal dependencies between the input variables and the glucose concentration; select simulation models of subcutaneous insulin absorption and meal absorption; identify an appropriate validation procedure, and identify realistic performance measures. Describes fundamentals of modeling techniques as applied to glucose control Covers model selection process and model validation Offers computer code on a companion website to show implementation of models and algorithms Features the latest developments in the field of diabetes predictive modeling

Individualized Care

Author : Riitta Suhonen
Publisher : Springer
ISBN 13 : 331989899X
Total Pages : 232 pages
Book Rating : 4.3/5 (198 download)

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Book Synopsis Individualized Care by : Riitta Suhonen

Download or read book Individualized Care written by Riitta Suhonen and published by Springer. This book was released on 2018-08-22 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed book is based on more than 20 years of researches on patient individuality, care and services of the continuously changing healthcare system. It describes how research results can be used to respond to challenges on individuality in healthcare systems. Service users’, patients’ or clients’ point of views on care and health services are urgently needed. This book describes the conceptualisation of the individualized nursing care phenomenon and the process development of the measuring instruments of that phenomenon in different contexts. It describes results from a variety of clinical contexts about individualized nursing care and explains factors associated with the perceptions and delivery of individualized nursing care from different point of views. This book may appeal to clinicians, nurses practitioners and researchers from many fields.

Diabetes Digital Health

Author : David C. Klonoff
Publisher : Elsevier
ISBN 13 : 0128174862
Total Pages : 311 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Diabetes Digital Health by : David C. Klonoff

Download or read book Diabetes Digital Health written by David C. Klonoff and published by Elsevier. This book was released on 2020-04-04 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes Digital Health brings together the multifaceted information surrounding the science of digital health from an academic, regulatory, industrial, investment and cybersecurity perspective. Clinicians and researchers who are developing and evaluating mobile apps for diabetes patients will find this essential reading, as will industry people whose companies are developing mobile apps and sensors. Provides valuable information for clinicians, researchers and industry about the design and evaluation of patient-facing diabetes adherence technologies Highlights cutting-edge topics that are presented and discussed at the Digital Diabetes Congress

Precision Medicine and Artificial Intelligence

Author : Michael Mahler
Publisher : Academic Press
ISBN 13 : 032385432X
Total Pages : 300 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Precision Medicine and Artificial Intelligence by : Michael Mahler

Download or read book Precision Medicine and Artificial Intelligence written by Michael Mahler and published by Academic Press. This book was released on 2021-03-12 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions Provides background, milestone and examples of precision medicine Outlines the paradigm shift towards precision medicine driven by value-based systems Discusses future applications of precision medicine research using AI Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine

New Strategies to Advance Pre/Diabetes Care: Integrative Approach by PPPM

Author : Mahmood S. Mozaffari
Publisher : Springer Science & Business Media
ISBN 13 : 9400759711
Total Pages : 549 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis New Strategies to Advance Pre/Diabetes Care: Integrative Approach by PPPM by : Mahmood S. Mozaffari

Download or read book New Strategies to Advance Pre/Diabetes Care: Integrative Approach by PPPM written by Mahmood S. Mozaffari and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended to provide up-to-date and emerging information in the field of diabetes mellitus with a focus on preventive, predictive and personalized medicine.

Progress and Challenges in Precision Medicine

Author : Mukesh Verma
Publisher : Academic Press
ISBN 13 : 0128095024
Total Pages : 344 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Progress and Challenges in Precision Medicine by : Mukesh Verma

Download or read book Progress and Challenges in Precision Medicine written by Mukesh Verma and published by Academic Press. This book was released on 2016-12-22 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development

The Personalized Medicine Revolution

Author : Pieter Cullis
Publisher : Greystone Books Ltd
ISBN 13 : 1771640383
Total Pages : 168 pages
Book Rating : 4.7/5 (716 download)

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Book Synopsis The Personalized Medicine Revolution by : Pieter Cullis

Download or read book The Personalized Medicine Revolution written by Pieter Cullis and published by Greystone Books Ltd. This book was released on 2015 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Cullis argues that personalized medicine, also known as precision medicine, is the biggest revolution of our time. By replacing the current one-size-fits-all approach to medicine with medical treatment based on a patient's unique molecular makeup, personalized medicine will radically change the role of doctors and patients and even the future of our species. Increasingly, instead of focusing on the treatment of chronic diseases, as they do today, doctors will focus on helping people prevent disease"--Amazon.com.

The Science of Health Disparities Research

Author : Irene Dankwa-Mullan
Publisher : John Wiley & Sons
ISBN 13 : 1119374812
Total Pages : 548 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis The Science of Health Disparities Research by : Irene Dankwa-Mullan

Download or read book The Science of Health Disparities Research written by Irene Dankwa-Mullan and published by John Wiley & Sons. This book was released on 2021-03-16 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrates the various disciplines of the science of health disparities in one comprehensive volume The Science of Health Disparities Research is an indispensable source of up-to-date information on clinical and translational health disparities science. Building upon the advances in health disparities research over the past decade, this authoritative volume informs policies and practices addressing the diseases, disorders, and gaps in health outcomes that are more prevalent in minority populations and socially disadvantaged communities. Contributions by recognized scholars and leaders in the field—featuring contemporary research, conceptual models, and a broad range of scientific perspectives—provide an interdisciplinary approach to reducing inequalities in population health, encouraging community engagement in the research process, and promoting social justice. In-depth chapters help readers better understand the specifics of minority health and health disparities while demonstrating the importance of advancing theory, refining measurement, improving investigative methods, and diversifying scientific research. In 26 chapters, the book examines topics including the etiology of health disparities research, the determinants of population health, research ethics, and research in African American, Asians, Latino, American Indian, and other vulnerable populations. Providing a unified framework on the principles and applications of the science of health disparities research, this important volume: Defines the field of health disparities science and suggests new directions in scholarship and research Explains basic definitions, principles, and concepts for identifying, understanding and addressing health disparities Provides guidance on both conducting health disparities research and translating the results Examines how social, historical and contemporary injustices may influence the health of racial and ethnic minorities Illustrates the increasing national and global importance of addressing health disparities Discusses population health training, capacity-building, and the transdisciplinary tools needed to advance health equity A significant contribution to the field, The Science of Health Disparities Research is an essential resource for students and basic and clinical researchers in genetics, population genetics, and public health, health care policymakers, and epidemiologists, medical students, and clinicians, particularly those working with minority, vulnerable, or underserved populations.

The Patient Equation

Author : Glen de Vries
Publisher : John Wiley & Sons
ISBN 13 : 111962214X
Total Pages : 288 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis The Patient Equation by : Glen de Vries

Download or read book The Patient Equation written by Glen de Vries and published by John Wiley & Sons. This book was released on 2020-08-11 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: How the data revolution is transforming biotech and health care, especially in the wake of COVID-19—and why you can’t afford to let it pass you by We are living through a time when the digitization of health and medicine is becoming a reality, with new abilities to improve outcomes for patients as well as the efficiency and success of the organizations that serve them. In The Patient Equation, Glen de Vries presents the history and current state of life sciences and health care as well as crucial insights and strategies to help scientists, physicians, executives, and patients survive and thrive, with an eye toward how COVID-19 has accelerated the need for change. One of the biggest challenges facing biotech, pharma, and medical device companies today is how to integrate new knowledge, new data, and new technologies to get the right treatments to the right patients at precisely the right times—made even more profound in the midst of a pandemic and in the years to come. Drawing on the fascinating stories of businesses and individuals that are already making inroads—from a fertility-tracking bracelet changing the game for couples looking to get pregnant, to an entrepreneur reinventing the treatment of diabetes, to Medidata's own work bringing clinical trials into the 21st century—de Vries shares the breakthroughs, approaches, and practical business techniques that will allow companies to stay ahead of the curve and deliver solutions faster, cheaper, and more successfully—while still upholding the principles of traditional therapeutic medicine and reflecting the current environment. How new approaches to cancer and rare diseases are leading the way toward precision medicine What data and digital technologies enable in the building of robust, effective disease management platforms Why value-based reimbursement is changing the business of life sciences How the right alignment of incentives will improve outcomes at every stage of the patient journey Whether you're a scientist, physician, or executive, you can't afford to let the moment pass: understand the landscape with this must-read roadmap for success—and see how you can change health care for the better.

Pharmacogenomics in Drug Discovery and Development

Author : Qing Yan
Publisher : Springer Nature
ISBN 13 : 107162573X
Total Pages : 618 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Pharmacogenomics in Drug Discovery and Development by : Qing Yan

Download or read book Pharmacogenomics in Drug Discovery and Development written by Qing Yan and published by Springer Nature. This book was released on 2022-09-06 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more. The collection of these theoretical and experimental approaches facilitates problem-solving by tackling the complexity of personalized drug discovery and development. Written by leading experts in their fields for the highly successful Methods in Molecular Biology series, the book aims to provide across-the-board resources to support the translation of pharmacogenomics into better individualized health care. Authoritative and up-to-date, Pharmacogenomics in Drug Discovery and Development, Third Edition aims to aid researchers in approaching the challenges in pharmacogenomics and personalized medicine with the introduction of these novel ideas and cutting-edge methodologies.

Obesity and Diabetes

Author : Joel Faintuch
Publisher : Springer Nature
ISBN 13 : 3030533700
Total Pages : 994 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Obesity and Diabetes by : Joel Faintuch

Download or read book Obesity and Diabetes written by Joel Faintuch and published by Springer Nature. This book was released on 2020-12-14 with total page 994 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, this comprehensive handbook provides a state-of-the-art overview of recent advances in drug and non-drug therapies for obesity and diabetes. It also addresses major comorbidities, covering topics such as, cardiovascular diseases, renal and neuropsychiatric disorders, appetite control and micro RNAs. Special attention is also devoted to pediatric care, including the latest recommendations for therapy and prevention. Obesity and type 2 diabetes are among the top global health-care budget concerns worldwide and impact professional practice at all levels: in hospitals, clinics and physicians’ offices alike. They prominently feature in headlines, and virtually no family, community or country is exempt from their protean, deleterious consequences. Furthermore, given the multiple intersections in their pathways, they often go hand in hand. The good news is that scientific advances in all fields, including genomics, metabolomics, lipidomics and microbiomics, are increasing our understanding of these two disease areas. At the same time, artificial intelligence, machine learning, mobile health and advanced implantable and external devices are rendering prevention and management more available, safe and cost-effective. In addition, bariatric and metabolic surgery has evolved from a niche specialty to an officially endorsed option for several modalities of obesity and diabetes. This book presents the latest lifestyle, pharmacological, surgical and non-surgical treatment options, including endoscopic intervention and cell therapy. Objectively reviewing natural and artificial sweeteners and critically examining issues such as public health initiatives, government mandated taxes for unhealthy foods and environmental planning, no stone is left unturned in gathering the latest practical information. As such, the book will appeal to seasoned specialists, as well as students and healthcare professionals in training.

Precision Medicine

Author : Hans-Peter Deigner
Publisher : Academic Press
ISBN 13 : 0128054336
Total Pages : 376 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Precision Medicine by : Hans-Peter Deigner

Download or read book Precision Medicine written by Hans-Peter Deigner and published by Academic Press. This book was released on 2018-02-15 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaining and interpreting results. This book is a valuable source for researchers in medical and life sciences, physicians and students with an interest in this emerging field of precision medicine. Provides technological aspects in precision medicine with aspects of modern statistical and bioinformatics models and methods Brings timely reviews on status and chances in precision medicine and associated aspects of data analysis, statistics and data interpretation Encompasses easy access to relevant approaches, interactions and original literature

Diabetes and Hypertension

Author : Samy I. McFarlane
Publisher : Springer Science & Business Media
ISBN 13 : 1603273573
Total Pages : 196 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Diabetes and Hypertension by : Samy I. McFarlane

Download or read book Diabetes and Hypertension written by Samy I. McFarlane and published by Springer Science & Business Media. This book was released on 2012-10-19 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes and hypertension have evolved as two of the modern day epidemics affecting millions of people around the world. These two common co-morbidities lead to substantial increase in cardiovascular disease, the major cause of morbidity and mortality of adults around the world. In Diabetes and Hypertension: Evaluation and Management, a panel of renowned experts address a range of critical topics -- from basic concepts in evaluation and management of diabetes and hypertension, such as dietary interventions, to evaluation and management of secondary hypertension in clinical practice. Other chapters focus on high cardiovascular risk populations such as those with coronary heart disease, chronic kidney disease and minority patients. In addition, evolving concepts and new developments in the field are presented in other chapters, such as prevention of type 2 diabetes and the epidemic of sleep apnea and its implication for diabetes and hypertension evaluation and management. An important title covering two of the most troubling disorders of our time, Diabetes and Hypertension: Evaluation and Management will provide the busy practitioner with cutting edge knowledge in the field as well as practical information that can translate into better care provided to the high-risk population of diabetics and hypertensive patients.

Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines

Author : Aihua Zhang
Publisher : John Wiley & Sons
ISBN 13 : 3527835741
Total Pages : 292 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines by : Aihua Zhang

Download or read book Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines written by Aihua Zhang and published by John Wiley & Sons. This book was released on 2021-08-20 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highlights the importance and benefit of mass spectrometry-based metabolomics for identifying biomarkers that accurately screen for potential biomarkers of diseases Mass spectrometry-based metabolomics offer new opportunities for biomarker discovery in complex diseases and may provide pathological understanding of diseases beyond traditional technologies. It is the systematic analysis of low-molecular-weight metabolites in biological samples and has been applied to discovering and identifying the perturbed pathways. Currently, mass spectrometry-based metabolomics has become an important tool in clinical research and the diagnosis of human disease. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines comprehensively presents the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics such as metabolites analysis, biomarker discovery, technical challenges, discovery of natural product, mechanism interpretation of action, discovery of active ingredients, clinical application and precision medicine, and enhancing their biomedical value in a real world of biomedicine, shedding light on the potential for spectrometry-based metabolomics. It highlights the value of mass spectrometry-based metabolomics and metabolism to address the complexity of herbal medicines in systems pharmacology, especially, to link phytochemical analysis with the assessment of pharmacological effect and therapeutic potential. Each chapter has been laid out with introduction, method, up-to-date literature, identification of biomarker, and applications Covers the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics in the discovery of biomarker, active ingredients, natural product, etc. Constitutes a unique and indispensable practical guide for any phytochemistry or related laboratory, and provides hands-on description of new techniques Provides a guide for new practitioners of pharmacologists, pharmacological scholars, drug developers, botanist, researchers of traditional medicines. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines provides a landmark of mass spectrometry-based metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all biomedical science fields.