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Author : Ki Sung Lee
Publisher :
ISBN 13 :
Total Pages : 258 pages
Book Rating : 4.:/5 (55 download)
Download or read book Pragmatic Image Reconstruction for High Resolution PET Scanners written by Ki Sung Lee and published by . This book was released on 2003 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ke Li (Electrical engineer)
Publisher :
ISBN 13 :
Total Pages : 124 pages
Book Rating : 4.:/5 (13 download)
Download or read book Novel PET Systems and Image Reconstruction with Actively Controlled Geometry written by Ke Li (Electrical engineer) and published by . This book was released on 2017 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron Emission Tomography (PET) provides in vivo measurement of imaging ligands that are labeled with positron emitting radionuclide. Since its invention, most PET scanners have been designed to have a group of gamma ray detectors arranged in a ring geometry, accommodating the whole patient body. Virtual Pinhole PET incorporates higher resolution detectors being placed close to the Region-of-Interest (ROI) within the imaging Field-of-View (FOV) of the whole-body scanner, providing better image resolution and contrast recover. To further adapt this technology to a wider range of diseases, we proposed a second generation of virtual pinhole PET using actively controlled high resolution detectors integrated on a robotic arm. When the whole system is integrated to a commercial PET scanner, we achieved positioning repeatability within 0.5 mm. Monte Carlo simulation shows that by focusing the high-resolution detectors to a specific organ of interest, we can achieve better resolution, sensitivity and contrast recovery.In another direction, we proposed a portable, versatile and low cost PET imaging system for Point-of-Care (POC) applications. It consists of one or more movable detectors in coincidence with a detector array behind a patient. The movable detectors make it possible for the operator to control the scanning trajectory freely to achieve optimal coverage and sensitivity for patient specific imaging tasks. Since this system does not require a conventional full ring geometry, it can be built portable and low cost for bed-side or intraoperative use. We developed a proof-of-principle prototype that consists of a compact high resolution silicon photomultiplier detector mounted on a hand-held probe and a half ring of conventional detectors. The probe is attached to a MicroScribe device, which tracks the location and orientation of the probe as it moves. We also performed Monte Carlo simulations for two POC PET geometries with Time-of-Flight (TOF) capability. To support the development of such PET systems with unconventional geometries, a fully 3D image reconstruction framework has been developed for PET systems with arbitrary geometry. For POC PET and the second generation robotic Virtual Pinhole PET, new challenges emerge and our targeted applications require more efficiently image reconstruction that provides imaging results in near real time. Inspired by the previous work, we developed a list mode GPU-based image reconstruction framework with the capability to model dynamically changing geometry. Ordered-Subset MAP-EM algorithm is implemented on multi-GPU platform to achieve fast reconstruction in the order of seconds per iteration, under practical data rate. We tested this using both experimental and simulation data, for whole body PET scanner and unconventional PET scanners. Future application of adaptive imaging requires near real time performance for large statistics, which requires additional acceleration of this framework.
Author : Daniele Panetta
Publisher : CRC Press
ISBN 13 : 100017588X
Total Pages : 97 pages
Book Rating : 4.0/5 (1 download)
Download or read book 3D Image Reconstruction for CT and PET written by Daniele Panetta and published by CRC Press. This book was released on 2020-10-11 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a practical guide to tomographic image reconstruction with projection data, with strong focus on Computed Tomography (CT) and Positron Emission Tomography (PET). Classic methods such as FBP, ART, SIRT, MLEM and OSEM are presented with modern and compact notation, with the main goal of guiding the reader from the comprehension of the mathematical background through a fast-route to real practice and computer implementation of the algorithms. Accompanied by example data sets, real ready-to-run Python toolsets and scripts and an overview the latest research in the field, this guide will be invaluable for graduate students and early-career researchers and scientists in medical physics and biomedical engineering who are beginners in the field of image reconstruction. A top-down guide from theory to practical implementation of PET and CT reconstruction methods, without sacrificing the rigor of mathematical background Accompanied by Python source code snippets, suggested exercises, and supplementary ready-to-run examples for readers to download from the CRC Press website Ideal for those willing to move their first steps on the real practice of image reconstruction, with modern scientific programming language and toolsets Daniele Panetta is a researcher at the Institute of Clinical Physiology of the Italian National Research Council (CNR-IFC) in Pisa. He earned his MSc degree in Physics in 2004 and specialisation diploma in Health Physics in 2008, both at the University of Pisa. From 2005 to 2007, he worked at the Department of Physics "E. Fermi" of the University of Pisa in the field of tomographic image reconstruction for small animal imaging micro-CT instrumentation. His current research at CNR-IFC has as its goal the identification of novel PET/CT imaging biomarkers for cardiovascular and metabolic diseases. In the field micro-CT imaging, his interests cover applications of three-dimensional morphometry of biosamples and scaffolds for regenerative medicine. He acts as reviewer for scientific journals in the field of Medical Imaging: Physics in Medicine and Biology, Medical Physics, Physica Medica, and others. Since 2012, he is adjunct professor in Medical Physics at the University of Pisa. Niccolò Camarlinghi is a researcher at the University of Pisa. He obtained his MSc in Physics in 2007 and his PhD in Applied Physics in 2012. He has been working in the field of Medical Physics since 2008 and his main research fields are medical image analysis and image reconstruction. He is involved in the development of clinical, pre-clinical PET and hadron therapy monitoring scanners. At the time of writing this book he was a lecturer at University of Pisa, teaching courses of life-sciences and medical physics laboratory. He regularly acts as a referee for the following journals: Medical Physics, Physics in Medicine and Biology, Transactions on Medical Imaging, Computers in Biology and Medicine, Physica Medica, EURASIP Journal on Image and Video Processing, Journal of Biomedical and Health Informatics.
Author : Debashish Pal
Publisher :
ISBN 13 :
Total Pages : 266 pages
Book Rating : 4.:/5 (233 download)
Download or read book Image Reconstruction for a High Resolution PET-insert Scanner written by Debashish Pal and published by . This book was released on 2008 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Magdy M. Khalil
Publisher : Springer
ISBN 13 : 3319400703
Total Pages : 621 pages
Book Rating : 4.3/5 (194 download)
Download or read book Basic Science of PET Imaging written by Magdy M. Khalil and published by Springer. This book was released on 2016-11-07 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.
Author : B. Bendriem
Publisher : Springer Science & Business Media
ISBN 13 : 9401734755
Total Pages : 180 pages
Book Rating : 4.4/5 (17 download)
Download or read book The Theory and Practice of 3D PET written by B. Bendriem and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of 3D methodology has recently been receiving increasing attention at many PET centres, and this monograph is an attempt to provide a state-of-the-art review of this methodology, covering 3D reconstruction methods, quantitative procedures, current tomography performance, and clinical and research applications. No such review has been available until now to assist PET researchers in understanding and implementing 3D methodology, and in evaluating the performance of the available imaging technology. In all the chapters, the subject matter is treated in sufficient depth to appeal equally to the physicist or engineer who wishes to establish the methodology, and to PET investigators with experience in 2D PET who wish to familiarize themselves with the concepts and advantages of 3D, and to be made aware of the pitfalls.
Author : Junwei Du
Publisher : Springer Nature
ISBN 13 : 303130666X
Total Pages : 248 pages
Book Rating : 4.0/5 (313 download)
Download or read book Gamma Ray Imaging written by Junwei Du and published by Springer Nature. This book was released on 2023-09-12 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will provide readers with a good overview of some of the most recent advances in the field of detector technology for gamma-ray imaging, especially as it pertains to new applications. There will be a good mixture of general chapters in both technology and applications in medical imaging and industrial testing. The book will have an in-depth review of the research topics from world-leading specialists in the field. The conversion of the gamma-ray signal into analog/digital value will be covered in some chapters. Some would also provide a review of CMOS chips for gamma-ray image sensors.
Author : Lin Fu
Publisher :
ISBN 13 : 9781124025315
Total Pages : pages
Book Rating : 4.0/5 (253 download)
Download or read book Residual Correction Algorithms for Statistical Image Reconstruction in Positron Emission Tomography written by Lin Fu and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron emission tomography (PET) is a radionuclide imaging modality that plays important roles in visualizing, targeting, and quantifying functional processes in vivo. High-resolution and quantitative PET images are reconstructed by solving large-scale inverse problems with iterative methods that incorporate accurate physics and noise modeling of the imaging process. The computation demands of PET image reconstruction are rapidly increasing as higher-resolution detectors, larger imaging field-of-view, and dynamic or adaptive data acquisition modes are being adopted by modern PET scanners. The trend of the increase in the computation demands is even faster than Moore's law that describes the exponential growth in the number of transistors placed on an integrated circuit. In this project a residual correction mechanism is introduced to PET image reconstruction to create computationally efficient yet accurate tomographic reconstruction algorithms. By using residual correction, reconstruction methods are able to adopt a more simplified physical model for fast computation while retaining the accuracy of the final solution. Residual correction can accelerate existing image reconstruction packages. It allows iterative reconstruction with more accurate physical models which are currently impractical due to the high computation cost. Two illustrative applications of the residual correction approach are provided. One is image reconstruction with an object-dependent Monte Carlo based physics model. The other is image reconstruction using an ultra fast GPU-accelerated simplified geometric model.
Author : Guillem Pratx
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (66 download)
Download or read book Image Reconstruction for High-resolution PET written by Guillem Pratx and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular imaging can interrogate subtle molecular disease signatures non-invasively in living subjects. Positron emission tomography (PET), one particular molecular imaging modality, is able to sense molecular signals deep within tissue. Although PET is well suited for imaging signals associated with cancerous lesions in humans, it is still unable to resolve very small (
Author : Ji-Ho Chang
Publisher :
ISBN 13 :
Total Pages : 320 pages
Book Rating : 4.:/5 (88 download)
Download or read book Image Reconstruction Algorithms for Achieving High-resolution Positron Emission Tomography Images written by Ji-Ho Chang and published by . This book was released on 2004 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Leticia Ortega Máynez
Publisher :
ISBN 13 :
Total Pages : 249 pages
Book Rating : 4.:/5 (861 download)
Download or read book Image reconstruction and data correction for very high resolution pre-clinical positron emission tomography with the quad-hidac pet system written by Leticia Ortega Máynez and published by . This book was released on 2008 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download Image Reconstruction Algorithms for Volume-imaging Pet Scanners [microform] PDF Online Free](https://books.google.com/books/content/images/frontcover/pCIsqAAACAAJ?fife=w200-h370)
Author : Kinahan, P. E. (Paul E.)
Publisher : Ann Arbor, Mich. : University Microfilms International
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.:/5 (187 download)
Download or read book Image Reconstruction Algorithms for Volume-imaging Pet Scanners [microform] written by Kinahan, P. E. (Paul E.) and published by Ann Arbor, Mich. : University Microfilms International. This book was released on 1994 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Aswin John Mathews
Publisher :
ISBN 13 :
Total Pages : 132 pages
Book Rating : 4.:/5 (98 download)
Download or read book A Four-dimensional Image Reconstruction Framework for PET Under Arbitrary Geometries written by Aswin John Mathews and published by . This book was released on 2014 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron Emission Tomography (PET) is a functional imaging modality with applications ranging from the treatment of cancer, studying neurological diseases and disease models. Virtual-Pinhole PET technology improves the image quality in terms of resolution and contrast recovery. The technology calls for having a detector with smaller crystals placed near a region of interest in a conventional whole-body PET scanner. The improvement is from the higher spatial sampling of the imaging area near the detector. A prototype half-ring PET insert built to study head-and-neck cancer imaging was extended to breast cancer imaging. We have built a prototype half-ring PET insert for head-and-neck cancer imaging applications. In the first half of this work, we extend the use of the insert to breast imaging and show that such a system provides high resolution images of breast and axillary lymph nodes while maintaining the full imaging field of view capability of a clinical PET scanner. We are focused on designing unconventional PET geometries for specific applications. A general purpose 4D PET reconstruction framework was created to estimate the radionuclide uptake in the subject. Quantitative estimation in PET requires precise modeling of PET physics. Data acquired in a PET scanner is well modeled as a Poisson counting process. Reconstruction given the forward model is implemented using MAP-OSEM. The framework is capable of reconstructing PET data under arbitrary position of the detector elements and different crystal sizes. A novel symmetry finding algorithm is created to reduce the system matrix size, without loss of resolution. The framework motivates investigation into different PET system geometries for different applications, as well as optimizing the design of PET systems. A generalized normalization procedure was developed to model unknown components. The programs are parallelized using OpenMP and MPI to run on small workstations as well as super-computing clusters. The performance of our reconstruction framework is presented through four novel and unconventional PET systems, each designed specifically for a different geometry. The Virtual-Pinhole half-ring system is a half-ring insert integrated into a Siemens Biograph-40, for head and neck imaging. The Flat-panel system is a modular insert system integrated into the Biograph-40, designed for breast cancer imaging. The MicroInsert II is the second generation full ring insert device, integrated into the MicroPET scanner to improve the resolution and contrast recovery of the MicroPET scanner. The Plant PET system is a PET system designed to image plants vertically, and integrated into a plant growth chamber. The improvement in speed/memory from symmetry finding is as high as a factor of 50 in some cases. Further improvements to the framework and state of the field are also discussed.
Author : Clay Houghton Holdsworth
Publisher :
ISBN 13 :
Total Pages : 574 pages
Book Rating : 4.:/5 ( download)
Download or read book Investigation of PET Image Reconstruction and Data Correction Techniques with Emphasis on an Accelerated Monte Carlo Simulation for Correction and Evaluation of PET written by Clay Houghton Holdsworth and published by . This book was released on 2002 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Richard John Walledge
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (643 download)
Download or read book High- Resolution 4D PET Image Reconstruction with the Quad-HIDAC. written by Richard John Walledge and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book High Resolution Image Reconstruction Method for a Double-plane PET System with Changeable Spacing *Supported by Knowledge Innovation Project of The Chinese Academy of Sciences (KJCX2-EW-N06). written by and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Breast-dedicated positron emission tomography (PET) imaging techniques have been developed in recent years. Their capacities to detect millimeter-sized breast tumors have been the subject of many studies. Some of them have been confirmed with good results in clinical applications. With regard to biopsy application, a double-plane detector arrangement is practicable, as it offers the convenience of breast immobilization. However, the serious blurring effect of the double-plane PET, with changeable spacing for different breast sizes, should be studied. We investigated a high resolution reconstruction method applicable for a double-plane PET. The distance between the detector planes is changeable. Geometric and blurring components were calculated in real-time for different detector distances, and accurate geometric sensitivity was obtained with a new tube area model. Resolution recovery was achieved by estimating blurring effects derived from simulated single gamma response information. The results showed that the new geometric modeling gave a more finite and smooth sensitivity weight in the double-plane PET. The blurring component yielded contrast recovery levels that could not be reached without blurring modeling, and improved visual recovery of the smallest spheres and better delineation of the structures in the reconstructed images were achieved with the blurring component. Statistical noise had lower variance at the voxel level with blurring modeling at matched resolution, compared to without blurring modeling. In distance-changeable double-plane PET, finite resolution modeling during reconstruction achieved resolution recovery, without noise amplification.
Author :
Publisher :
ISBN 13 :
Total Pages : 864 pages
Book Rating : 4.0/5 ( download)
Download or read book 2003 IEEE Nuclear Science Symposium written by and published by . This book was released on 2004 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt:
