Posttranscriptional Regulation Of Thyrotropin B Subunit Gene Expression By Thyroid Hormone

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Clinical Management of Thyroid Disease E-Book

Author : Fredric E. Wondisford
Publisher : Elsevier Health Sciences
ISBN 13 : 1437719694
Total Pages : 435 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Clinical Management of Thyroid Disease E-Book by : Fredric E. Wondisford

Download or read book Clinical Management of Thyroid Disease E-Book written by Fredric E. Wondisford and published by Elsevier Health Sciences. This book was released on 2009-06-26 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Management of Thyroid Disease is an exciting new book edited by Fredric Wondisford, MD—developer of the revolutionary new drug, Thyrotropin—and Sally Radovick, MD, with contributions from experts in the field. It fulfills the niche of a succinct, clinical resource to help you translate research into practice. This full-color volume offers valuable information on thyroid cancer and non-cancerous lesions, the effect of drugs on thyroid function, genetic disorders, and more in an accessible, easy-to-read consistent format. Presents the expertise of authors and editorial staff comprised of leaders in the field of thyroid research and clinical management for the best-qualified guidance on diagnosis and treatment. Provides a full-color, comprehensive approach that makes valuable information easy to locate and quick to read. Covers relevant topics applicable to all levels of training and expertise to serve as a detailed clinical reference on everything from the basic to the sophisticated. Captures research advances on hot topics such as thyroid cancer and non-cancerous lesions, the effect of drugs on thyroid function, and genetic disorders so that you can incorporate them into the way you treat patients.

Thyroid Hormone Metabolism

Author : Georg Hennemann
Publisher : Marcel Dekker
ISBN 13 :
Total Pages : 656 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Thyroid Hormone Metabolism by : Georg Hennemann

Download or read book Thyroid Hormone Metabolism written by Georg Hennemann and published by Marcel Dekker. This book was released on 1986 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetic Diagnosis of Endocrine Disorders

Author : Roy E. Weiss
Publisher : Academic Press
ISBN 13 : 0128011343
Total Pages : 462 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Genetic Diagnosis of Endocrine Disorders by : Roy E. Weiss

Download or read book Genetic Diagnosis of Endocrine Disorders written by Roy E. Weiss and published by Academic Press. This book was released on 2015-10-09 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Diagnosis of Endocrine Disorders, Second Edition provides users with a comprehensive reference that is organized by endocrine grouping (i.e., thyroid, pancreas, parathyroid, pituitary, adrenal, and reproductive and bone), discussing the genetic and molecular basis for the diagnosis of various disorders. The book emphasizes the practical nature of diagnosing a disease, including which tests should be done for the diagnosis of diabetes mellitus in adults and children, which genes should be evaluated for subjects with congenital hypothyroidism, which genetic tests should be ordered in obese patients or for those with parathyroid carcinoma, and the rationale behind testing for multiple endocrine neoplasias. - Offers a clear presentations of pharmacogenetics and the actual assays used in detecting endocrine diseases - Teaches the essentials of the genetic basis of disease in each major endocrine organ system - Offers expert advice from genetic counselors on how to use genetic information in counseling patients - Includes new chapters on the genetics of lipid disorders and glycogen storage diseases, genetics of hypoglycemia, and whole genome/exome sequencing

The Thyroid and Its Diseases

Author : Markus Luster
Publisher : Springer
ISBN 13 : 331972102X
Total Pages : 751 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis The Thyroid and Its Diseases by : Markus Luster

Download or read book The Thyroid and Its Diseases written by Markus Luster and published by Springer. This book was released on 2019-01-08 with total page 751 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an up-to-date and comprehensive guide to all the common thyroid disorders that may be seen by internists, endocrinologists, nuclear medicine physicians, and endocrine surgeons. While the fundamentals of thyroid hormone function and regulation in health and disease are well covered, the primary focus is on the clinical approach to thyroid disease, with detailed coverage of both initial diagnosis and management and the role of imaging. Because most endocrine diseases are chronic and lifelong, special emphasis is placed on long-term management and the common pitfalls that may be encountered by the clinician. The editors are internationally acknowledged leaders in the field of thyroid disease and have gathered an outstanding team of authors, all of whom are also highly expert in their respective areas, but who, equally importantly, write in a clear and lucid style. The numerous isotope scan and ultrasonographic images ensure that the book will serve as a valuable reference atlas to which the physician will return again and again.

Molecular Basis of Thyroid Hormone Action

Author : Jack H. Oppenheimer
Publisher :
ISBN 13 :
Total Pages : 530 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Basis of Thyroid Hormone Action by : Jack H. Oppenheimer

Download or read book Molecular Basis of Thyroid Hormone Action written by Jack H. Oppenheimer and published by . This book was released on 1983 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Basis of Thyroid Hormone Action focuses on the actions of thyroid hormones in eukaryotic cells. This book discusses the profound effects of thyroid hormones on the growth, development, and metabolism of practically all tissues of higher organisms. Organized into 15 chapters, this volume starts with an overview of the kinetic interrelationships of hormone bound to specific receptors and hormone associated with other tissue and plasma pools in living animals. This book then discusses the thyroid hormone receptor, a chromatin-associated protein that appears to mediate the actions of the ...

Molecular Cloning of Hormone Genes

Author : Joel F. Habener
Publisher : Springer Science & Business Media
ISBN 13 : 1461248248
Total Pages : 451 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Molecular Cloning of Hormone Genes by : Joel F. Habener

Download or read book Molecular Cloning of Hormone Genes written by Joel F. Habener and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The peptide hormones are small proteins that regulate cellular metabolism through their specific interactions with tissues of the endocrine, nervous, and immune systems, as well as in embry onic development. During the past ten years, refinements in the techniques of recombinant DNA technology have resulted in the cloning of genes encoding approximately 50 different hormonal and regulatory peptides, including those in which the peptides themselves and the mRNAs encoding the peptides are present in only trace amounts in the tissues of origin. In addition to provid ing the coding sequences of recognized hormonal and regulatory peptides, gene sequencing has uncovered new bioactive peptides encoded in the precursor pro hormones that are then liberated along with the hormonal peptides during cellular cleavages of the precursors. The encoding of multiple peptides in a single mono cistronic mRNA appears to be a genetic mechanism for the gener ation of biologic diversification without requiring amplification of gene sequences. Two of the objectives in the assembly of this book are to pre sent, in one volume, the known primary structures of the genes encoding several of the polypeptide hormones and related regulatory peptides, and to provide an account of the various ap proaches that have been used to identify and select the cloned genes encoding these polypeptides. The contents of the two in troductory chapters are intended to provide the reader with a brief background of the approaches to gene cloning and the struc ture and expression of hormone-encoding genes.

Endocrinology Adult and Pediatric: The Thyroid Gland

Author : Leslie J. De Groot
Publisher : Elsevier Health Sciences
ISBN 13 : 032322153X
Total Pages : 488 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Endocrinology Adult and Pediatric: The Thyroid Gland by : Leslie J. De Groot

Download or read book Endocrinology Adult and Pediatric: The Thyroid Gland written by Leslie J. De Groot and published by Elsevier Health Sciences. This book was released on 2013-06-01 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Access all of the latest advances in thyroid disorder management on your favorite eReader with Endocrinology: Adult and Pediatric: The Thyroid Gland! Brought to you by the same leading endocrinologists responsible for the highly acclaimed two-volume Endocrinology clinical reference, this new thyroid disorder eBook enables you to give your patients the benefit of today's best know-how. - Stay abreast of the newest knowledge and advances in thyroid disease, including the use of thyroglobulin assays and ultrasound vs. isotope scanning in thyroid cancer; the latest understanding of Graves' eye disease; the use of I-131 in management of multinodular goiter; T4 transport defects causing thyroid hormone resistance; best practices in management of thyroid disease during pregnancy; and much more. - Benefit from authoritative guidance on thyroid testing. - Make the best clinical decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion. - Count on all the authority that has made Endocrinology, 6th Edition, edited by Drs. Jameson and DeGroot, the go-to clinical reference for endocrinologists worldwide. - Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.

Thyroid Hormone Disruption and Neurodevelopment

Author : Noriyuki Koibuchi
Publisher : Springer
ISBN 13 : 1493937375
Total Pages : 207 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Thyroid Hormone Disruption and Neurodevelopment by : Noriyuki Koibuchi

Download or read book Thyroid Hormone Disruption and Neurodevelopment written by Noriyuki Koibuchi and published by Springer. This book was released on 2016-11-11 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. However, the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first book to comprehensively describe the effect of thyroid hormone disruption in the central nervous system. The first section deals with the disruption of thyroid hormone action at the molecular level. First the authors provide a summary of the possible molecular mechanisms of thyroid hormone action in the brain, then they discuss several factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a “repressor” of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals. Thus, several different kind of animal models may be used to clarify the role of thyroid hormone and its receptor in the brain. In the third section, human studies on thyroid disease and neurodevelopment will be introduced. Although endemic cretinism induced by iodine deficiency and sporadic cretinism by various thyroid mutation are well known, the pathophysiological mechanisms that create each abnormal phenotype are not fully understood.

Werner & Ingbar's The Thyroid

Author : Lewis E. Braverman
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 145112063X
Total Pages : 925 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Werner & Ingbar's The Thyroid by : Lewis E. Braverman

Download or read book Werner & Ingbar's The Thyroid written by Lewis E. Braverman and published by Lippincott Williams & Wilkins. This book was released on 2012-10-08 with total page 925 pages. Available in PDF, EPUB and Kindle. Book excerpt: Werner & Ingbar’s The Thyroid: A Fundamental and Clinical Text, 10th Edition has been extensively revised and streamlined to deliver the most comprehensive coverage of the thyroid including anatomy, development, biochemistry, physiology, pathophysiology, and treatment of all thyroid disorders. Entirely new chapters on the surgical management of thyroid cancer, thyroid disruptors, and thyroid hormone analogs are in this edition. New authors and an international group of contributors elevate this classic text that includes extensive clinical coverage of thyroid dysfunction’s effects on other organ systems. Also addressed are clinical controversies regarding the ageing thyroid, subclinical hypothyroidism and hyperthyroidism and thyroid disease in pregnancy. New to this edition: · Twenty-three chapters authored by new contributors and international experts · A companion website with fully searchable text for quick reference · Three new chapters discuss surgical management of thyroid cancer, thyroid disruptors, and thyroid hormone analogs to keep you up-to-date on the latest advances in the field

Tissue-Specific Cell Signaling

Author : Joana Vieira Silva
Publisher : Springer Nature
ISBN 13 : 3030444368
Total Pages : 444 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Tissue-Specific Cell Signaling by : Joana Vieira Silva

Download or read book Tissue-Specific Cell Signaling written by Joana Vieira Silva and published by Springer Nature. This book was released on 2020-05-29 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters. This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors. Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Molecular Endocrinology

Author : Bruce D. Weintraub
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 552 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Endocrinology by : Bruce D. Weintraub

Download or read book Molecular Endocrinology written by Bruce D. Weintraub and published by Lippincott Williams & Wilkins. This book was released on 1995 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Fish Oocyte

Author : Patrick J. Babin
Publisher : Springer Science & Business Media
ISBN 13 : 1402062354
Total Pages : 513 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis The Fish Oocyte by : Patrick J. Babin

Download or read book The Fish Oocyte written by Patrick J. Babin and published by Springer Science & Business Media. This book was released on 2007-08-17 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive overview on egg production in fish, from the standpoint of the oocyte. It covers oocyte development, maturation, hydration and fertilization. The book places special emphasis on using state-of-the-art tools for discerning the ultra-structure of the follicle and genomic/proteomic tools to fully understand biological basis of fish reproduction.

Graves’ Disease

Author : Basil Rapoport
Publisher : Springer Science & Business Media
ISBN 13 : 9780792377900
Total Pages : 328 pages
Book Rating : 4.3/5 (779 download)

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Book Synopsis Graves’ Disease by : Basil Rapoport

Download or read book Graves’ Disease written by Basil Rapoport and published by Springer Science & Business Media. This book was released on 2000-06-30 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the perspective of the investigator, Graves' disease is a fascinating disorder with unique features and opportunities for study. The discovery in 1956 that Graves' disease was caused by a humoral factor, later shown to be an antibody to the TSH receptor, was a triumph for modern investigative medicine. Rapid progress is now being made in (i) understanding the molecular interaction between autoantibodies and the TSH receptor, (ii) identifying the genes that contribute to the predisposition to disease, (iii) developing an animal model of Graves' disease, and (iv) identifying the long-sought orbital antigen in ophthalmopathy. From the clinical standpoint, although Graves' disease is eminently treatable, there is no definitive cure. None of the therapeutic options are ideal. It is hoped that rapid progress in understanding the pathogenesis of the disease will lead to the ultimate goal of some form of immunotherapy that will make antithyroid drugs, radioiodine and thyroidectomy obsolete. The chapters in Graves' Disease: Pathogenesis and Treatment represent the viewpoints of many prominent clinicians and investigators working in the field. The editors are grateful for their contributions which cover an unusually comprehensive compendium of subjects relating to the disease.

Brain Disorders in Critical Illness

Author : Robert D. Stevens
Publisher : Cambridge University Press
ISBN 13 : 1107434424
Total Pages : 457 pages
Book Rating : 4.1/5 (74 download)

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Book Synopsis Brain Disorders in Critical Illness by : Robert D. Stevens

Download or read book Brain Disorders in Critical Illness written by Robert D. Stevens and published by Cambridge University Press. This book was released on 2013-09-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.

Endocrinology - E-Book

Author : J. Larry Jameson
Publisher : Elsevier Health Sciences
ISBN 13 : 1455711268
Total Pages : 3076 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Endocrinology - E-Book by : J. Larry Jameson

Download or read book Endocrinology - E-Book written by J. Larry Jameson and published by Elsevier Health Sciences. This book was released on 2010-05-18 with total page 3076 pages. Available in PDF, EPUB and Kindle. Book excerpt: ENDOCRINOLOGY, edited by J. Larry Jameson, MD, PhD and Leslie J. De Groot, MD, has been considered the definitive source in its field for decades. Now this landmark reference has been exhaustively updated to bring you the latest clinical guidance on all aspects of diagnosis and treatment for the full range of endocrine and metabolism disorders, including new information on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors. Entirely new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis keep you well informed on today’s hot topics. You’ll benefit from unique, global perspectives on adult and pediatric endocrinology prepared by an international team of renowned authorities. This reference is optimally designed to help you succeed in your demanding practice and ensure the best possible outcomes for every patient. Overcome virtually any clinical challenge with detailed, expert coverage of every area of endocrinology, authored by hundreds of leading luminaries in the field. Provide state-of-the-art care with comprehensive updates on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors ... brand-new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis ... expanded coverage of sports performance, including testosterone, androgen research, and bone growth and deterioration ... and the newest discoveries in genetics and how they affect patient care. Make the best clinical decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion. Rapidly consult with trusted authorities thanks to new expert-opinion treatment strategies and recommendations. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information more quickly, while still getting the complete coverage you expect.

Animal Growth Regulation

Author : Dennis R. Campion
Publisher : Springer Science & Business Media
ISBN 13 : 1468488724
Total Pages : 413 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Animal Growth Regulation by : Dennis R. Campion

Download or read book Animal Growth Regulation written by Dennis R. Campion and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biotechnological advances of recent years have put us on the brink of unprecedented gains in animal productivity. Manipulation of animal growth rate and composition of gain is now possible by a variety of techniques. Ex amples include ingestion of beta-adrenergic agonists, injection of somatotropin, castration, immunization, and gene insertion. Animal Growth Regulation ad dresses modem concepts of growth regulation with an emphasis on agricul turally important animals. This emphasis is not exclusive, as many situations exist in which the only information available was generated in other species, and this information has been included for the sake of clarity and completeness. However, because of the overall orientation of this volume, particular attention has been given to the regulation of skeletal muscle, adipose tissue, and bone growth. Certain hormones and growth factors have a profound influence on growth regulation and this basic physiological knowledge is being harnessed to maniplilate growth. Thus, considerable emphasis has been given to growth hor mone-somatomedinlinsulinlike growth factor regulation of cell and tissue growth. The involvement of peptides coded by protooncogenes and of negative growth regulators, such as transforming growth factor-l3, represents an emerging area of molecular biology wherein basic knowledge offers potential exploitation for growth manipulation. Opportunities also exist for regulation of protein turn over, especially from the standpoint of protein degradation. Therefore, a place was reserved for these topics in order to provide relevant basic knowledge.

Stress-Activated Protein Kinases

Author : Francesc Posas
Publisher : Springer Science & Business Media
ISBN 13 : 3540755691
Total Pages : 322 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Stress-Activated Protein Kinases by : Francesc Posas

Download or read book Stress-Activated Protein Kinases written by Francesc Posas and published by Springer Science & Business Media. This book was released on 2008-01-24 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signaling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signaling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis. Written by international experts, the book will appeal to cell biologists and biochemists.