Polymeric Micelles Principles Perspectives And Practices

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Polymeric Micelles: Principles, Perspectives and Practices

Author : Sachin Kumar Singh
Publisher : Springer Nature
ISBN 13 : 9819903610
Total Pages : 302 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Polymeric Micelles: Principles, Perspectives and Practices by : Sachin Kumar Singh

Download or read book Polymeric Micelles: Principles, Perspectives and Practices written by Sachin Kumar Singh and published by Springer Nature. This book was released on 2023-04-08 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book thoroughly reviews the advancements in design and applications of Polymeric Micelles (PMs) in drug delivery. It provides information on the synthesis of amphiphilic block copolymers and their types, functional chemistry for targeting and sensing, and biomedical applications. The book further provides the possibilities for designing PMs in a range of drug delivery approaches. The book addresses the molecular parameters of amphiphilic block copolymers that are required for functionalizing PMs for drug delivery applications. Additionally, the book presents recent advances in applications of PMs such as co-delivery, sensing, theranostics, delivery of nucleic acids, and proteins. Towards the end, it discusses different physico-chemical strategies to enhance the stability and drug retention of polymeric micelles and reviews the preclinical and clinical toxicity and immunogenicity-related aspects of polymeric micelles. This book is an invaluable source for academics, research, and industry professionals working in the field of polymeric micelles and drug delivery.

Polymeric Micelles for Drug Delivery

Author : Prashant Kesharwani
Publisher : Woodhead Publishing
ISBN 13 : 0323886299
Total Pages : 716 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Polymeric Micelles for Drug Delivery by : Prashant Kesharwani

Download or read book Polymeric Micelles for Drug Delivery written by Prashant Kesharwani and published by Woodhead Publishing. This book was released on 2022-08-18 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric Micelles for Drug Delivery provides a comprehensive overview on the synthesis, characterization and application of polymeric micelles in drug delivery applications. The use of nanomedicines and carriers, such as polymeric micelles, has made it possible to deliver drugs, genes and therapeutic agents to localized disease sites to maximize clinical benefit while limiting unwanted side effects. This book thoroughly reviews the development and application of polymeric micelles for drug delivery, covering various polymer types and the synthesis, characterization and pharmacokinetics of different micelles. Subsequent chapters go on to look at the range of drug delivery applications of polymeric micelles – such as mucosal and transdermal – and the assorted stimuli-responsive micelles available. The book concludes with an important analysis of the environmental and regulatory aspects associated with micelle development and clinical translation. Explores how polymeric micelles can be utilized in a range of different drug delivery approaches, from traditional oral delivery to ocular and dermal delivery Describes the various polymer types used in the synthesis and characterization of polymeric micelles Covers recent advances in polymeric micelles, such as drug co-delivery, triblock polymeric micelles, delivery of genetic materials, and more

Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications

Author : Neeraj Mishra
Publisher : Springer Nature
ISBN 13 : 9819969174
Total Pages : 440 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications by : Neeraj Mishra

Download or read book Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications written by Neeraj Mishra and published by Springer Nature. This book was released on 2023-11-29 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.

Nanocarrier Drug Delivery Systems

Author : Prashant L. Pingale
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3111320960
Total Pages : 831 pages
Book Rating : 4.1/5 (113 download)

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Book Synopsis Nanocarrier Drug Delivery Systems by : Prashant L. Pingale

Download or read book Nanocarrier Drug Delivery Systems written by Prashant L. Pingale and published by Walter de Gruyter GmbH & Co KG. This book was released on 2024-08-19 with total page 831 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology can treat diseases by site-specific and target-oriented delivery of precise medicines. Nanomaterials improve the efficacy of drugs and selective diagnosis. The book covers detection and treatment. It explains the use of nanocarriers for a variety of diseases such as cardiovascular and respiratory diseases, cancer, and ulcerative colitis. It includes topical, transdermal, and ocular drug delivery and combined medication delivery.

Biogenic Nanomaterials for Environmental Sustainability: Principles, Practices, and Opportunities

Author : Maulin P. Shah
Publisher : Springer Nature
ISBN 13 : 3031459563
Total Pages : 501 pages
Book Rating : 4.0/5 (314 download)

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Book Synopsis Biogenic Nanomaterials for Environmental Sustainability: Principles, Practices, and Opportunities by : Maulin P. Shah

Download or read book Biogenic Nanomaterials for Environmental Sustainability: Principles, Practices, and Opportunities written by Maulin P. Shah and published by Springer Nature. This book was released on 2024-01-03 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental pollution is a worldwide concern now. A major section of the world population is struggling for drinking water. Polluted soil is resulting into low agricultural productivity and thus creating challenges in the way of sustainable livelihood of a large section of human population. Biological treatment can offer both green solutions for wastewater treatment and resource recovery as well. Like algal-based systems can be utilized for wastewater treatment and production of biofuels from the biomass grown on the wastewater. Bio-based nanomaterials have been extensively studied for their employability in the health care, process optimization, water resource management, dealing with environmental pollutants, biosensors, and many others. Bioprospecting of novel biological agents, bio-based products, and bioresource recovery are paving the way for sustainable development as they are providing local solutions for a number of problems. In this proposed book, we start with the introduction to bio-nanotechnological principles and later on discuss bio-based nanomaterials employability for a diverse range of applications from environment to energy to health care. This book provides with current trends in bio-nanotechnology for anthropogonic purposes, prospects, challenges, and way forward.

Continuous Processing of Polymeric Micelles

Author : Anand Gupta
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (133 download)

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Book Synopsis Continuous Processing of Polymeric Micelles by : Anand Gupta

Download or read book Continuous Processing of Polymeric Micelles written by Anand Gupta and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric micelles are nano-particulate core-shell structures that form spontaneously in aqueous solutions of block copolymers composed of hydrophilic and hydrophobic portions when their concentration surpasses the critical micelle concentration (CMC) at a given temperature. They are used as drug delivery systems for highly potent and extremely hydrophobic drugs such as anticancer or anti-inflammatory agents to enhance safety, efficacy, and solubility. Critical quality attributes of polymeric micelles, that tend to govern their destiny in the human body are their size and polydispersity. Ensuring manufacturing consistency for complex drug products such as polymeric nanoparticles is challenging. This can be attributed, in part, to the complex nature of the manufacturing processes and a lack of understanding of critical material attributes such as drug-polymer interactions and critical process parameters such as organic to aqueous phase ratios. Currently, the manufacturing of polymeric micelles in the pharmaceutical industry is via batch processing which has various disadvantages such as scalability, irreproducibility, down-time between batches and other issues leading to product waste, and increased expenses. To overcome potential batch-to-batch variation typically observed using traditional batch manufacturing processes, the current work focused on continuous processing of polymeric micelles and the establishment and assessment of key material attributes and process parameters. A modified continuous processing platform (based on the University of Connecticut prototype liposomal manufacturing platform) was successfully developed and built to produce polymeric micelles. Moreover, this study outlines the relationship between critical independent variables (such as polymer concentration, organic to aqueous flow rate ratios and temperature) and critical quality attributes (such as the size and polydispersity) of polymeric micelles produced by continuous processing. The controlled nanoprecipitation process achieved via co-axial co-flow and radial mixing of jets improved the control and reproducibility of polymeric micelle particle size and polydispersity compared to batch processing. Multiple design of experiments studies were implemented to produce polymeric micelles with controlled size in the range between 15 and 70 nm. Four different molecular weight block copolymers (i.e. PEG-PLA-4kD, and PEG-PCL 7kD, 14kD and 28kD) were investigated to produce polymeric micelles using the turbulent jet co-flow technology. Moreover, curcumin-loaded polymeric micelles, as an example of an API containing polymeric micelles, were produced to establish and validate the continuous processing system. Paclitaxel-loaded polymeric micelles were produced to demonstrate the system's capacity to produce Q1/Q2 equivalent drug product similar to the reference listed drug product: Genexol®PM.

Compendium of Polymer Terminology and Nomenclature

Author : Richard G Jones
Publisher : Royal Society of Chemistry
ISBN 13 : 1847559425
Total Pages : 465 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Compendium of Polymer Terminology and Nomenclature by : Richard G Jones

Download or read book Compendium of Polymer Terminology and Nomenclature written by Richard G Jones and published by Royal Society of Chemistry. This book was released on 2009-01-19 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: The IUPAC system of polymer nomenclature has aided the generation of unambiguous names that re ect the historical development of chemistry. However, the explosion in the circulation of information and the globalization of human activities mean that it is now necessary to have a common language for use in legal situations, patents, export-import regulations, and environmental health and safety information. Rather than recommending a ‘unique name’ for each structure, rules have been developed for assigning ‘preferred IUPAC names’, while continuing to allow alternatives in order to preserve the diversity and adaptability of nomenclature. Compendium of Polymer Terminology and Nomenclature is the only publication to collect the most important work on this subject into a single volume. It serves as a handy compendium for scientists and removes the need for time consuming literature searches. One of a series issued by the International Union of Pure and Applied Chemistry (IUPAC), it covers the terminology used in many and varied aspects of polymer science as well as the nomenclature of several di erent types of polymer including regular and irregular single-strand organic polymers, copolymers and regular double-strand (ladder and spiro) organic polymers.

Fundamental Principles of Polymeric Materials

Author : Stephen L. Rosen
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Fundamental Principles of Polymeric Materials by : Stephen L. Rosen

Download or read book Fundamental Principles of Polymeric Materials written by Stephen L. Rosen and published by Wiley-Interscience. This book was released on 1993 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanded discussion of extended-chain crystals and their commercial developments; phase behavior in polymer-solvent systems; and three-dimensional stress and strain introduction to the Flory-Huggins theory; the "modified Cross" model; and Tobolsky's "Procedure X" for extracting discrete relaxation times and moduli from data. New sections on scaleup calculations for the laminar flow of non-Newtonian fluids; liquid-crystal polymers; and group-transfer polymerization, including a quantitative treatment of Ziegler-Natta polymerization with worked-out examples. All kinetic expressions are written in terms of conversions (rather than monomer concentration) for greater generality and ease of application. Kinetic expressions incorporate the possibility of a variable-volume reaction mass, and feature new examples to illustrate the effects of variable volume.

Polymeric Drug Delivery Systems

Author : Glen S. Kwon
Publisher : CRC Press
ISBN 13 : 9780824725327
Total Pages : 680 pages
Book Rating : 4.7/5 (253 download)

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Book Synopsis Polymeric Drug Delivery Systems by : Glen S. Kwon

Download or read book Polymeric Drug Delivery Systems written by Glen S. Kwon and published by CRC Press. This book was released on 2005-04-12 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing four major classes of polymers for drug delivery-water-soluble polymers, hydrogels, biodegradable polymers, and polymer assemblies-this reference surveys efforts to adapt, modify, and tailor polymers for challenging molecules such as poorly water-soluble compounds, peptides/proteins, and plasmid DNA.

Surfactant Science

Author : Steven John Abbott
Publisher :
ISBN 13 : 9781605954844
Total Pages : 0 pages
Book Rating : 4.9/5 (548 download)

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Book Synopsis Surfactant Science by : Steven John Abbott

Download or read book Surfactant Science written by Steven John Abbott and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise and practical reference for understanding surfactant systems Offers original formulas and phase diagrams for improved surfactant design and performance¿ Equations related to online computer apps allow readers to test their own data Written in a conversational form, with a focus on real-world problems and troubleshooting Applications to detergents, coatings, cosmetics, soil and water remediation, and biosurfactants Full chapter included on foam and anti-foam science

Principles of Polymerization

Author : George Odian
Publisher : John Wiley & Sons
ISBN 13 : 0471274003
Total Pages : 850 pages
Book Rating : 4.4/5 (712 download)

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Book Synopsis Principles of Polymerization by : George Odian

Download or read book Principles of Polymerization written by George Odian and published by John Wiley & Sons. This book was released on 2004-02-09 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of a classic text and reference The large chains of molecules known as polymers are currently used in everything from "wash and wear" clothing to rubber tires to protective enamels and paints. Yet the practical applications of polymers are only increasing; innovations in polymer chemistry constantly bring both improved and entirely new uses for polymers onto the technological playing field. Principles of Polymerization, Fourth Edition presents the classic text on polymer synthesis, fully updated to reflect today's state of the art. New and expanded coverage in the Fourth Edition includes: * Metallocene and post-metallocene polymerization catalysts * Living polymerizations (radical, cationic, anionic) * Dendrimer, hyperbranched, brush, and other polymer architectures and assemblies * Graft and block copolymers * High-temperature polymers * Inorganic and organometallic polymers * Conducting polymers * Ring-opening polymer ization * In vivo and in vitro polymerization Appropriate for both novice and advanced students as well as professionals, this comprehensive yet accessible resource enables the reader to achieve an advanced, up-to-date understanding of polymer synthesis. Different methods of polymerization, reaction parameters for synthesis, molecular weight, branching and crosslinking, and the chemical and physical structure of polymers all receive ample coverage. A thorough discussion at the elementary level prefaces each topic, with a more advanced treatment following. Yet the language throughout remains straightforward and geared towards the student. Extensively updated, Principles of Polymerization, Fourth Edition provides an excellent textbook for today's students of polymer chemistry, chemical engineering, and materials science, as well as a current reference for the researcher or other practitioner working in these areas.

Handbook of Encapsulation and Controlled Release

Author : Munmaya Mishra
Publisher : CRC Press
ISBN 13 : 1482232340
Total Pages : 1516 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Handbook of Encapsulation and Controlled Release by : Munmaya Mishra

Download or read book Handbook of Encapsulation and Controlled Release written by Munmaya Mishra and published by CRC Press. This book was released on 2015-12-01 with total page 1516 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of encapsulation, especially microencapsulation, is a rapidly growing area of research and product development. The Handbook of Encapsulation and Controlled Release covers the entire field, presenting the fundamental processes involved and exploring how to use those processes for different applications in industry. Written at a level comp

Materials for Medical Applications

Author : Firdos Alam Khan
Publisher : CRC Press
ISBN 13 : 100092470X
Total Pages : 293 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Materials for Medical Applications by : Firdos Alam Khan

Download or read book Materials for Medical Applications written by Firdos Alam Khan and published by CRC Press. This book was released on 2023-09-22 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses advanced knowledge about the synthesis and application of materials in the medical field for diagnostic and therapeutic conditions. These materials have been extensively used in various biological and medical applications, especially in drug delivery, tumor screening, bioimaging, diagnosis, and therapies. Materials for Medical Applications provides comprehensive but concise information about materials and their medical applications. The readers will get information about the trends in materials and their medical applications, as well as current material-based products that are used in the medical field. The book has 11 chapters, where shapes, sizes, and structural differences of materials and methods of synthesis have been described, and a few chapters are also dedicated to the characterization of materials and their medical applications. The book also discusses how materials are tested in research laboratories, preclinical (animal) trials, and clinical (human) trials, and how material-based products go through various regulatory and safety phases before reaching patients. It also discusses topics such as materials delivery, imaging, and treatments for various diseases. It includes a chapter dedicated to regulatory guidelines and policies in the application of nanomaterials and will include current clinical trial information on the materials. Finally, the book has topics such as health safety, toxicity, dosages, and long-term implications of materials. This book is intended for researchers, material scientists, and students in bioengineering, biomedical engineering, and biopharmaceuticals working on the development of biomaterials.

Polymer Colloids

Author : Rodney Priestley
Publisher : Royal Society of Chemistry
ISBN 13 : 1788014170
Total Pages : 442 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Polymer Colloids by : Rodney Priestley

Download or read book Polymer Colloids written by Rodney Priestley and published by Royal Society of Chemistry. This book was released on 2019-12-02 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Academic and industrial research around polymer-based colloids is huge, driven both by the development of mature technologies, e.g. latexes for coatings, as well as the advancement of new materials and applications, such as building blocks for 2D/3D structures and medicine. Edited by two world-renowned leaders in polymer science and engineering, this is a fundamental text for the field. Based on a specialised course by the editors, this book provides the reader with an invaluable single source of reference. The first section describes formation, explaining basic properties of emulsions and dispersion polymerization, microfluidic approaches to produce polymer-based colloids and formation via directed self-assembly. The next section details characterisation methodologies from microscopy and small angle scattering, to surface science and simulations. The final chapters close with applications, including Pickering emulsions and molecular engineering for materials development. A comprehensive guide to polymer colloids, with contributions by leaders in their respective areas, this book is a must-have for researchers and practitioners working across polymers, soft matter and chemical and molecular engineering.

Food Emulsions

Author : David Julian McClements
Publisher : CRC Press
ISBN 13 : 1420039431
Total Pages : 633 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Food Emulsions by : David Julian McClements

Download or read book Food Emulsions written by David Julian McClements and published by CRC Press. This book was released on 2004-12-16 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food Emulsions: Principles, Practice, and Techniques, Second Edition introduces the fundamentals of emulsion science and demonstrates how this knowledge can be applied to better understand and control the appearance, stability, and texture of many common and important emulsion-based foods. Revised and expanded to reflect recent developments, this s

Handbook of Industrial Water Soluble Polymers

Author : Peter A. Williams
Publisher : John Wiley & Sons
ISBN 13 : 0470994193
Total Pages : 344 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Handbook of Industrial Water Soluble Polymers by : Peter A. Williams

Download or read book Handbook of Industrial Water Soluble Polymers written by Peter A. Williams and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural and synthetic water soluble polymers are used in a wide range of familiar industrial and consumer products, including coatings and inks, papers, adhesives, cosmetics and personal care products. They perform a variety of functions without which these products would be significantly more expensive, less effective or both. Written for research, development and formulation chemists, technologists and engineers at graduate level and beyond in the fine and specialty chemicals, polymers, food and pharmaceutical industries, the Handbook of Industrial Water Soluble Polymers deals specifically with the functional properties of both natural and synthetic water soluble polymers. By taking a function based approach, rather than a “polymer specific” approach the book illustrates how polymer structure leads to effect, and shows how different polymer types can be employed to achieve appropriate product properties.

Nanoengineered Biomaterials for Advanced Drug Delivery

Author : Masoud Mozafari
Publisher : Elsevier
ISBN 13 : 0081029861
Total Pages : 820 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Nanoengineered Biomaterials for Advanced Drug Delivery by : Masoud Mozafari

Download or read book Nanoengineered Biomaterials for Advanced Drug Delivery written by Masoud Mozafari and published by Elsevier. This book was released on 2020-06-17 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoengineered Biomaterials for Advanced Drug Delivery explores the latest advances in the applications of nanoengineered biomaterials in drug delivery systems. The book covers a wide range of biomaterials and nanotechnology techniques that have been used for the delivery of different biological molecules and drugs in the human body. It is an important resource for biomaterials scientists and engineers working in biomedicine and those wanting to learn more on how nanoengineered biomaterials are being used to enhance drug delivery for a variety of diseases. Nanoengineered biomaterials have enhanced properties that make them more effective than conventional biomaterials as both drug delivery agents, and in the creation of new drug delivery systems. As nanoengineering becomes more cost-effective, nanoengineered biomaterials have become more widely used within biomedicine. Offers an informed overview on how nanoengineering biomaterials enhance their properties for drug delivery applications Discusses the major applications of nanoengineered biomaterials for drug delivery Outlines the major challenges for successfully implementing nanoengineered biomaterials into existing drug delivery systems