Pointers to Cancer Prognosis

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Publisher : Springer Science & Business Media
ISBN 13 : 940093291X
Total Pages : 377 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Pointers to Cancer Prognosis by : B.A. Stoll

Download or read book Pointers to Cancer Prognosis written by B.A. Stoll and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last 30 years have seen little improvement in the age-adjusted mortality rates for most common types of cancer, and until we develop more effective and less damaging treatment modalities for these tumours, selection of each patient's treatment must depend on prognostic pointers. These lead to a calculated trade off between our estimate of likely benefit to the patient, as against cost in terms of quality of life. But changes have occurred recently in our understanding of the traditional prognostic pointers used for selecting such individualised treatment. First, it is increasingly recognised that the stage at which a tumour presents is more related to the chromo logical age of the tumour (how far it has progressed before diagnosis) than to its biological characteristics. While advanced chronological age of the tumour may predict a greater likelihood of early death, only biological criteria can predict the tumour growth rate, the likelihood of prolonged survival, the likely course of the disease after the first recurrence or the likehood of response to systemic therapy. Second, there is increasing use of failure analysis in relating the clinical and biological characteristics of tumours to their response to standard treatments. In the past, the relationship was interpreted mainly in terms of survival rate, but the site and timing of first recurrence and the pattern and timing of subsequent spread provide a better assessment of the control possible from local or systemic therapy.

Pointers to Cancer Prognosis

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Publisher :
ISBN 13 : 9789400932920
Total Pages : 388 pages
Book Rating : 4.9/5 (329 download)

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Book Synopsis Pointers to Cancer Prognosis by : B a Stoll

Download or read book Pointers to Cancer Prognosis written by B a Stoll and published by . This book was released on 1987-02-28 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Battling and Beating Cancer

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Publisher : Battling and Beating Cancer
ISBN 13 : 1441530525
Total Pages : 319 pages
Book Rating : 4.4/5 (415 download)

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Book Synopsis Battling and Beating Cancer by : Scott Seaman

Download or read book Battling and Beating Cancer written by Scott Seaman and published by Battling and Beating Cancer. This book was released on 2009-07 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Battling And Beating Cancer - The Cancer Survival Book "is an inspiring story of a couple fighting cancer together. It provides a poignant and enlightening look at cancer from the perspectives of patient and caregiver - covering the highs and lows from diagnosis, to surgery, to chemotherapy, to radiation, to follow-up, to fighting back for people impacted by cancer. The book covers cancer survival from A to Z, including (1) the basics about cancer in general and blood cancers (lymphoma, leukemia, and myeloma) in particular; (2) selecting the best doctors and assembling your health care team; (3) understanding tests, diagnostic tools, and staging; (4) obtaining a prompt and proper diagnosis and getting second opinions; (5) taking advantage of conventional treatments, revolutionary treatments, and clinical trials; (6) selecting the most effective treatment for your cancer; (7) surviving your hospital stay; (8) understanding survival rates and making appropriate adjustments to put the odds in your favor; (9) developing a cancer warrior mentality; (10) dealing with fears, scanxiety, and thriving as a cancer survivor: (11) taking advantage of complementary and integrative therapies and a healthy lifestyle to help you beat cancer; (12) understanding the role of the immune system in beating cancer; (13) explaining why blood cancer research is the superhighway to curing cancer; and (14) setting out the authors national call to action to cure cancer through cancer education and awareness, patient advocacy, fundraising, organizing, cogent research, and public policy advocacy. "Battling and Beating Cancer" is loaded with checklists, tips, and tools, including: a detailed list of questions to ask your doctors at each critical phase pointers doctors may forget to tell you a checklist of legal and insurance documents tips for dealing with common side effects of treatment a listing of organizations, websites, and resources available to help you get the support and information you need about your type of cancer and the treatments and clinical trials available to you. It also includes a patient s medical information workbook to help you record relevant information. You will want to bring the book with you so that you have important information at your finger tips. The Foreword is written by leading hematologist-oncologist Stephanie A. Gregory, MD and transplant physician Henry C. Fung, MD, Rush University Medical Center. Aptly titled, this book is all about beating cancer."

Hypercalcemia of Malignancy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642850731
Total Pages : 238 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Hypercalcemia of Malignancy by : Friedhelm Raue

Download or read book Hypercalcemia of Malignancy written by Friedhelm Raue and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypercalcemia is the most common life-threatening metabolic disorder associated with cancer. The pathophysiological, epidemiological and clinical aspects of hypercalcemia of malignancy are presented in this issue, with a focus on the recently discovered humoral factor responsible for the development of hypercalcemia. With a better understanding of the pathophysiology of this condition and the development of new potent drugs, capable of inhibiting bone resorption, especially bisphosphonates, the clinician will be more successful in correcting hypercalcemia in the great majority of patients.

Prognostic Factors in Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 3642793959
Total Pages : 303 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Prognostic Factors in Cancer by : Paul Hermanek

Download or read book Prognostic Factors in Cancer written by Paul Hermanek and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: M. K. Gospodarowicz, P. Hermanek, and D. E. Henson Attention to innovations in cancer treatment has tended to eclipse the importance of prognostic assessment. However, the recognition that prognostic factors often have a greater impact on outcome than available therapies and the proliferation of biochemical, molecular, and genetic markers have resulted in renewed interest in this field. The outcome in patients with cancer is determined by a combination of numerous factors. Presently, the most widely recognized are the extent of disease, histologic type of tumor, and treatment. It has been known for some time that additional factors also influence outcome. These include histologic grade, lymphatic or vascular invasion, mitotic index, performance status, symptoms, and most recently genetic and biochemical markers. It is the aim of this volume to compile those prognostic factors that have emerged as important determinants of outcome for tumors at various sites. This compilation represents the first phase of a more extensive process to integrate all prognostic factors in cancer to further enhance the prediction of outcome following treatment. Certain issues surround ing the assessment and reporting of prognostic factors are also considered. Importance of Prognostic Factors Prognostic factors in cancer often have an immense influence on outcome, while treatment often has a much weaker effect. For example, the influence of the presence of lymph node involvement on survival of patients with metastatic breast cancer is much greater than the effect of adjuvant treatment with tamoxifen in the same group of patients [5].

Journal of the National Cancer Institute

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Publisher :
ISBN 13 :
Total Pages : 524 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Journal of the National Cancer Institute by :

Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 2003 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Effect of Cancer On Quality of Life

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Publisher : CRC Press
ISBN 13 : 1000142035
Total Pages : 374 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Effect of Cancer On Quality of Life by : David Osoba

Download or read book Effect of Cancer On Quality of Life written by David Osoba and published by CRC Press. This book was released on 2021-11-01 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is comprised of extensive reviews and instructional chapters that discuss the quality of life in several aspects of cancer. The first six chapters deal with conceptual issues relating to measuring quality of life in adult and pediatric populations with cancer. The next five chapters provide practical information on how to select quality-of-life measures, the statistical analysis of trials, economic evaluations to be considered, and some possible abuses of quality-of-life measures. Five chapters review the results of studies using selected quality-of-life measures and provide recent information on their performance. These are followed by three chapters dealing with specific issues relating to nausea and vomiting associated with cancer therapy. Three chapters are devoted to the problems of assessing and controlling pain in patients who have cancer. There are also two chapters that deal with the quality of life in palliative care. Effect of Cancer on Quality of Life is intended for all who have an interest in measuring the quality of life in patients with cancer. This includes investigators who are just entering the field and can benefit from instructions on how to conduct quality-of-life research, as well as those who are experienced in conducting this kind of research.

New Trends in Gastric Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 9400921675
Total Pages : 194 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis New Trends in Gastric Cancer by : P.I. Reed

Download or read book New Trends in Gastric Cancer written by P.I. Reed and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the fact that the incidence of gastric cancer is declining in the Western world, it remains a significant problem with respect to accurate diagnosis and treatment since it has a high mortality rate. In June 1989 an International Conference was held at the University of Rome "La Sapienza" entitled "New Trends in Gastric Cancer: Background and videosurgery". During this meeting background information on the aetiopathogenesis of gastric cancer was presented together with talks and video presentations on the latest advances in the treatment of gastric carcinoma, both from the European and Japanese experience. Because of the poor prognosis of gastric carcinoma there is increasing pressure for early detection. Some of the problems in the early detection of gastric carcinoma are discussed together with methods of surveillance of high-risk subjects. It is generally accepted that the surgical approach to gastric carcinoma should take into account the site and extent of the lesion and there are chapters on new methods for pre and intraoperative staging of the disease which allow a more logical approach to surgery. A comparison between Japanese and Western rule and results was attempted and reasons for the differences were investigated. Since the field is still evolving not all aspects could be covered, and those angles not approached in this book will be addressed in a second International Conference to be held in Rome in June 1990.

Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury

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Publisher : Springer Science & Business Media
ISBN 13 : 1461538742
Total Pages : 493 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury by : Kenneth V. Honn

Download or read book Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury written by Kenneth V. Honn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the First International Conference on Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury held in Detroit, Michigan on October 11-14, 1989. The program consisted of 83 oral and 29 poster presentations, 74 of which are included in these proceedings. The major sponsors of the conference were the Armed Forces Radiobiology Research Institute, located in Bethesda, Maryland, the Radiation Oncology Research and Development Center of the Gershenson Radiation Oncology Center, Harper Hospital in Detroit, Michigan, and Schering AG of West Germany. Eighteen other organizations provided additional support. The conference was unique in its attempt to link the eicosanoid and lipid researchers in the radiobiology and cancer disciplines. The diverse roles that eicosanoids and other bioactive lipids play in these biological phenomena including the participation of lipid oxidation in conversion of procarcinogens, positive and negative modulation of tumor growth, immunomodulation, tissue injury, and yet protection and enhancement of cancer therapy, necessitated scientific interaction to sort out and understand these complex and sometimes contradictory observations. The success of this effort is reflected not only through these proceedings, but also through the decision to continue the conference series with a second meeting to be held in Berlin between September 17-21, 1991.

Women at High Risk to Breast Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 9400913273
Total Pages : 140 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Women at High Risk to Breast Cancer by : B.A. Stoll

Download or read book Women at High Risk to Breast Cancer written by B.A. Stoll and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reprint of the 1989 edition of this book has been made necessary by continuing demand after rapid exhaustion of the first printing. In the two years since its appearance, there has been relatively little expansion of knowledge on this topic, and its massive accumulation of references still remains an authoritative guide in the difficult task of developing a national breast cancer prevention model. At the same time, its thesis has been sharpened by the publication of a companion volume Approaches to Breast Cancer Prevention (Kluwer, 1991) similarly edited byrne. Breast cancer is on the increase throughout the Western world where it is a major source of anxiety among women. The disease is also becoming more frequent in Asian and South American countries where once it was relatively uncommon. Multiple fac tors are suspected of promoting the disease and the increasing risk is attributed to recent changes in life-style and diet. This book is intended to provide an authorita tive and balanced survey of the latest research into the genetic, familial, hormonal, reproductive, nutritional, social and geographic factors known to be associated with an increased predisposition to the disease.

Genetics of Colorectal Cancer for Clinical Practice

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792321002
Total Pages : 210 pages
Book Rating : 4.3/5 (21 download)

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Book Synopsis Genetics of Colorectal Cancer for Clinical Practice by : Fred H. Menko

Download or read book Genetics of Colorectal Cancer for Clinical Practice written by Fred H. Menko and published by Springer Science & Business Media. This book was released on 1993-07-31 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is a collective term for a heterogeneous group of diseases. In a large proportion of cases, the condition is attributable to genetic predisposition. Those directly involved in the treatment of patients with cancer of the large bowel are confronted to an increasing degree with the genetic aspects of the disease. In familial and hereditary forms of the disorder periodic screening of the close relatives of the patients can in principle prevent disease and death from colorectal cancer. Presymptomatic diagnosis by means of DNA technology is now possible in many cases of familial adenomatous polyposis. Genetic diagnosis will be increasingly important for the identification of high-risk groups. This book summarizes those aspects of the genetics of colorectal cancer that are important for clinical pracice. It has been stated that clinicians can contribute to the goal of reducing mortality from cancer by asking each patient about his or her family history of cancer. The aim of this book is to provide a guideline for the management of those situations in which the family history of colorectal cancer is found to be positive.

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury

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Publisher : Springer Science & Business Media
ISBN 13 : 1461535204
Total Pages : 765 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury by : Santosh Nigam

Download or read book Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury written by Santosh Nigam and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent decades eicosanoids have been attracting an increasing amount of attention as a result of their important physiological roles in many areas of biology and medicine. The eicosanoids comprise the prostaglandins, thromboxanes and leukotrienes and are products of arachidonic acid, an essential polyunsaturated fatty acid stored in tissue phospholipids. Disturbances of eicosanoids and their metabolic products play a regulatory role in many types of cell injuries and diseases. One of the most exciting areas of eicosanoid research pinpoints their participation in the control of cell proliferation and differentiation. Eicosanoids form a link between different fields of research into such areas as cancer, inflammation and radiation-induced injury. This link provided the impetus for the development of the conference series of which the present volume represents the proceedings of the Second International Conference, held in Berlin in October 1991.

Magnetic Resonance in Experimental and Clinical Oncology

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Publisher : Springer Science & Business Media
ISBN 13 : 1461306914
Total Pages : 395 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Magnetic Resonance in Experimental and Clinical Oncology by : Jeffrey L. Evelhoch

Download or read book Magnetic Resonance in Experimental and Clinical Oncology written by Jeffrey L. Evelhoch and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, techniques have been developed and implemented to observe metabolism noninvasively in localized regions of intact, living experimental animals and humans through the use of magnetic resonance spectroscopy (MRS). At the same time, magnetic resonance imaging (MRI) techniques developed in the 1970s and refined in this decade have been increasingly applied as a powerful clinical tool to probe human anatomy. Because of the unusual metabolic and physiologic characteristics of malignant tissues, oncology has been one of the primary focuses of the application of both MRS and MRI. Although considerable progress has been made in oncologic applications of magnetic resonance (MR), further research is needed to realize the full potential of MR in this area. Consequently, the 21st Annual Detroit Cancer Symposium entitled "Magnetic Resonance in Experimental and Clin ical Oncology" was organized to provide a forum for researchers in the field to report the state of the art of MRS and MRI in oncol ogy, to discuss future goals for MRS and MRI in oncology, and to define the research needed to meet those goals. The major emphasis of the symposium was on MRS due to both the recent widespread availability of clinical MRS instrumentation and the extensive amount of animal MRS research performed over the past half decade.

Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development

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Publisher : Springer Science & Business Media
ISBN 13 : 1461534925
Total Pages : 413 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development by : Frederick A. Valeriote

Download or read book Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development written by Frederick A. Valeriote and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of the 22nd Annual Detroit Cancer Symposium was the presentation and discussion of cytotoxic agents, with a significant portion of the symposium including the exciting frontiers of drug discovery being explored by the National Cooperative Drug Discovery Groups (NCDDG) Program. The symposium brought together a large number of investigators from government, universities and pharmaceutical companies involved in the discovery and development of new anticancer agents. Exciting new leads were presented and the status of others presently under development was discussed. Of particular significance has been the initiation of renewed efforts in the area of natural product drug discovery, where the discovery of new cytotoxics is very promising at the moment. A number of major changes have occurred during the last decade in research on drug discovery of cytotoxic agents. Critical reviews of a number of the models and concepts underlying drug discovery represented a continuous thread throughout the meeting, being constantly discussed in terms of their advantages, disadvantages and capabilities of discovering solid tumor active anticancer agents. A recent development which is to be much applauded and which portends to great discoveries is the new relationship formed between Government, University of Industry. The NCDDG mechanism which stimulates this interaction is an inexpensive manner to greatly magnify the drug discovery and development effort nationally. Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development represents a forum which will become the major mode for bringing together these three different components in the equation to regularly discuss new results and ideas.

Childhood Leukemia: Present Problems and Future Prospects

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Publisher : Springer Science & Business Media
ISBN 13 : 146153898X
Total Pages : 266 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Childhood Leukemia: Present Problems and Future Prospects by : Noburo Kobayashi

Download or read book Childhood Leukemia: Present Problems and Future Prospects written by Noburo Kobayashi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty years ago when Children's Cancer Association of Japan was born, the diagnosis of childhood leukemia amounted to a death sentence. Only 20% or so of children with leukemia survived more than 5 years. Since then, enormous improvements have been achieved regarding our understanding on the etiology, diagnosis, and the treatment of childhood leukemia. Now, 70% of children with leukemia survive and enter adult life. Even though the improved survival rate of children with leukemia represents a medical success story, we now face new problems. The first problem is the fact that we still lose 20-30% of patients with childhood leukemia. To address this problem, we need to understand the etiology, epidemiology, and biology of leukemia; to identify the patients at greater risk; and to develop adequate treatments. The second problem is the treatment itself. Even though efficacious, the modem treatment for leukemia is a grueling experience for children and their families. We should develop a total care system for families and children based on a deep understanding of their needs. The third problem is the aftereffects of the treatment and of cured leukemia. Extensive radiation and chemotherapy have an entirely different spectrum of long-term effects on children than on adults. These treatments in the early stage of life, when the mind and body are developing, create many physical and psychological problems. These are the present problems of childhood leukemia.

Gastric Carcinoma

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Publisher : Springer Science & Business Media
ISBN 13 : 1461236363
Total Pages : 206 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Gastric Carcinoma by : Jürgen Hotz

Download or read book Gastric Carcinoma written by Jürgen Hotz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric Carcinoma/Classification, Diagnosis, and Therapy presents the most current perspective on gastric carcinoma, with particular emphasis on the surgical and chemotherapeutic modalities that offer hope for future treatment. The book discusses epidemiology, pathogenesis, and precancerous and clinical stage classification of the disease and provides valid practical guidelines for stage-specific diagnosis, therapy, and patient guidance. Topics explored include endoscopic criteria for premalignant lesions and early gastric carcinoma; clinical staging of gastric cancer by ultrasound, computerized tomography, and magnetic resonance tomography; surgical treatment of carcinomas of the gastroesophageal junction; possibilities for palliative treatment in surgical practice for advanced tumors; adjuvant treatment of gastric cancer; and chemotherapy of advanced gastric carcinomas in elderly and high-risk patients.

National Library of Medicine Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 1028 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1028 pages. Available in PDF, EPUB and Kindle. Book excerpt: