Platelets as Players in Neuropathologies: Novel Diagnostic and Therapeutic Targets

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889716872
Total Pages : 120 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Platelets as Players in Neuropathologies: Novel Diagnostic and Therapeutic Targets by : Jacqueline Monique Orian

Download or read book Platelets as Players in Neuropathologies: Novel Diagnostic and Therapeutic Targets written by Jacqueline Monique Orian and published by Frontiers Media SA. This book was released on 2021-11-23 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Platelets in Thrombotic and Non-Thrombotic Disorders

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Author :
Publisher : Springer
ISBN 13 : 3319474626
Total Pages : 1445 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Platelets in Thrombotic and Non-Thrombotic Disorders by : Paolo Gresele

Download or read book Platelets in Thrombotic and Non-Thrombotic Disorders written by Paolo Gresele and published by Springer. This book was released on 2017-03-08 with total page 1445 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.

Neuroscientific Basis of Dementia

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Publisher : Birkhäuser
ISBN 13 : 3034882254
Total Pages : 294 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Neuroscientific Basis of Dementia by : Chikako Tanaka

Download or read book Neuroscientific Basis of Dementia written by Chikako Tanaka and published by Birkhäuser. This book was released on 2012-12-06 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: In step with our growing lifespan, dementia is becoming a widespread handicap to the health and well-being of individuals and a burden on human society world-wide. The increasing prevalence of this tragic condition has stimulated an explosion of scientific research in the last ten years, which resulted in numerous profound insights and technical innovations. This timely volume presents both an overall and a detailed overview of the current worldwide knowledge about the neuroscientific basis of dementia. Leading authorities in their fields provide a far-reaching synthesis of all topics in dementia research, including pathogenesis of dementia, neuroimaging of the earliest alterations, potential biological and genetic markers for Alzheimer`s Disease and new therapeutic strategies. Each chapter discusses clinical implications and areas of controversy, highlights the wide range of current and future therapeutic possibilities and indicates promising directions for further research...

Traumatic Brain and Spinal Cord Injury

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1107007437
Total Pages : 361 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Traumatic Brain and Spinal Cord Injury by : Cristina Morganti-Kossmann

Download or read book Traumatic Brain and Spinal Cord Injury written by Cristina Morganti-Kossmann and published by Cambridge University Press. This book was released on 2012-07-19 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.

Molecular Mechanisms of Neurodegenerative Diseases

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Publisher : Springer Science & Business Media
ISBN 13 : 1592590063
Total Pages : 416 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Molecular Mechanisms of Neurodegenerative Diseases by : Marie-Francoise Chesselet

Download or read book Molecular Mechanisms of Neurodegenerative Diseases written by Marie-Francoise Chesselet and published by Springer Science & Business Media. This book was released on 2000-10-19 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the unprecedented identification of new mutation mechanisms in neurodegenerative diseases and the emergence of common mechanisms among diseases that were once considered unrelated, neurobiologists are poised for the development of new therapies based on high throughput screenings and a better understanding of the molecular and cellular mechanisms leading to neurodegeneration. In Molecular Mechanisms of Neurodegenerative Diseases, Marie-Francoise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from different yet complementary points of view. Focusing on Alzheimer's, Parkinson's, and CAG triplet repeat diseases, the authors show how studies of cellular and genetically engineered animal models have enhanced our understanding of the molecular mechanisms of neurodegenerative diseases and may lead to the development of new therapeutics. Topics include the role of Ab toxicity, glial cells, and inflammation in Alzheimer's disease; the formation of abnormal protein fragments across several diseases, the impact of dopamine and mitochondrial dysfunction on neurodegeneration; and the potential of genetics to identify the molecular mechanisms of neurodegenerative diseases. Authoritative and insightful, Molecular Mechanisms of Neurodegenerative Diseases synthesizes the novel ideas and concepts now emerging to create a fresh understanding of neurodegenerative disorders, one that promises to lead to powerful new therapies that prevent, delay the onset, slow the progression, or even cure these cruel diseases.

Brain Neurotrauma

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Publisher : CRC Press
ISBN 13 : 1466565993
Total Pages : 718 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Brain Neurotrauma by : Firas H. Kobeissy

Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Role of Proteases in the Pathophysiology of Neurodegenerative Diseases

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0306468476
Total Pages : 304 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Role of Proteases in the Pathophysiology of Neurodegenerative Diseases by : Abel Lajtha

Download or read book Role of Proteases in the Pathophysiology of Neurodegenerative Diseases written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects for which experimental results are difficult to interpret. The breakdown part of protein turnover in vivo, particularly in nervous tissue, was such a subject in the past – it was difficult to measure and difficult to explore the mechanisms involved. For factors that influence protein metabolism, it was thought that protein content, function, and distribution are controlled only by the synthetic mechanisms that can supply the needed specificity and response to stimuli. The role of breakdown was thought to be only a general metabolic digestion, elimination of excess polypeptides. We now know that the role of breakdown is much more complex: it has multiple functions, it is coupled to turnover, and it can affect protein composition, function, and synthesis. In addition to eliminating abnormal proteins, breakdown has many modulatory functions: it serves to activate and inactivate enzymes, modulate membrane function, alter receptor channel properties, affect transcription and cell cycle, form active peptides, and much more. The hydrolysis of peptide bonds often involves multiple steps, many enzymes, and cycles (such as ubiquination), and often requires the activity of enzyme complexes. Their activation, modification, and inactivation can thus play an important role in biological functions, with numerous families of proteases participating. The specific role of each remains to be elucidated.

Programmed Cell Death in Cancer Progression and Therapy

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 140206554X
Total Pages : 362 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Programmed Cell Death in Cancer Progression and Therapy by : Roya Khosravi-Far

Download or read book Programmed Cell Death in Cancer Progression and Therapy written by Roya Khosravi-Far and published by Springer Science & Business Media. This book was released on 2007-12-29 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Programmed cell death (PCD) plays pivotal roles in tumor progression, cancer therapeutics and resistance of tumor cells to therapy. This book examines the mechanisms involved in mediating and regulating PCD in cancer. It also provides a detailed indication of the utility of PCD in cancer therapy. The book features chapters on the current and future of RNA interference in therapeutics and Pathways involved in Stem Cell Survival and Death.

Prevention and Treatment of Age-related Diseases

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402050585
Total Pages : 365 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Prevention and Treatment of Age-related Diseases by : Suresh I.S. Rattan

Download or read book Prevention and Treatment of Age-related Diseases written by Suresh I.S. Rattan and published by Springer Science & Business Media. This book was released on 2007-05-09 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a broad-ranging assessment of current efforts of the molecular, cellular, hormonal, nutritional and lifestyle strategies being tested and applied by biogerontologists in the search for effective means of intervention, prevention and treatment of age-related diseases, and for achieving healthy old age. Employing a semi-academic style, the book presents data from experimental systems, while focusing primarily on their applications to humans in the prevention and treatment of age-related impairments.

Neurologic Differential Diagnosis

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Publisher : Cambridge University Press
ISBN 13 : 1107014557
Total Pages : 693 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Neurologic Differential Diagnosis by : Alan B. Ettinger

Download or read book Neurologic Differential Diagnosis written by Alan B. Ettinger and published by Cambridge University Press. This book was released on 2014-04-17 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unique case-based guide to generating diagnostic possibilities based on the patients' symptoms. Invaluable for psychiatrists and neurologists.

Temporomandibular Joint and Airway Disorders

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Author :
Publisher : Springer
ISBN 13 : 3319763679
Total Pages : 260 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Temporomandibular Joint and Airway Disorders by : G. Gary Demerjian

Download or read book Temporomandibular Joint and Airway Disorders written by G. Gary Demerjian and published by Springer. This book was released on 2018-11-03 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on the local and systemic manifestations and correlates of temporomandibular joint disorders (TMDs) encompasses the two intertwined facets of translational science – translational research and translational effectiveness – as they relate specifically to TMDs. The first part of the book, on recent translational research, focuses on topics such as the neuroanatomy and neurophysiology of the trigeminal nerve and trigeminal network system, the manifestations of neuroinflammation in TMDs, and the molecular mechanisms underlying TMDs. The second part discusses the clinical effectiveness of treatment approaches from the perspective of evidence-based dentistry, with careful attention to the critical relationships between dental malocclusions, the signs and symptoms of TMDs, and airway/breathing disorders. Interventions to correct for malocclusal conditions that lead to TMDs are examined, with explanation of the ways in which they can ameliorate a variety of local and systemic symptoms. This will be an excellent reference book for established practitioners, residents, interns, and students as well as a powerful cutting-edge document for researchers in the field.

Personalized Anaesthesia

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1107579252
Total Pages : 315 pages
Book Rating : 4.1/5 (75 download)

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Book Synopsis Personalized Anaesthesia by : Pedro L. Gambús

Download or read book Personalized Anaesthesia written by Pedro L. Gambús and published by Cambridge University Press. This book was released on 2020-02-06 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a modern vision of anaesthesia, integrating technology and knowledge, to change how anaesthesia is taught and practised.

Damage Control Management in the Polytrauma Patient

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Author :
Publisher : Springer
ISBN 13 : 3319524291
Total Pages : 338 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Damage Control Management in the Polytrauma Patient by : Hans-Christoph Pape

Download or read book Damage Control Management in the Polytrauma Patient written by Hans-Christoph Pape and published by Springer. This book was released on 2017-04-04 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an unparalleled source of cutting-edge information on every aspect of rescue, trauma management, and fracture care in the polytrauma/multiple injured patient. Damage control surgery is approached logically and systematically by dividing treatment into phases. The common goal of treating life-threatening conditions first, then treating major pelvic and extremity fractures, requires cooperation among all major disciplines and subspecialties involved in the care of polytrauma patients, and the book is accordingly multidisciplinary in nature. It is edited by pioneers in the field and the authors are all acclaimed experts. This second, revised and updated edition of Damage Control Management in the Polytrauma Patient will be invaluable for all clinicians who must weigh life-saving operations against limb-threatening conditions, including emergency personnel, trauma surgeons, orthopaedic traumatologists, and anesthesiologists.

Subcellular Proteomics

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402059434
Total Pages : 397 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Subcellular Proteomics by : Eric Bertrand

Download or read book Subcellular Proteomics written by Eric Bertrand and published by Springer Science & Business Media. This book was released on 2007-08-29 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes the new developments that made subcellular proteomics a rapidly expanding area. It examines the different levels of subcellular organization and their specific methodologies. In addition, the book includes coverage of systems biology that deals with the integration of the data derived from these different levels to produce a synthetic description of the cell as a system.

Neurotransmitters in Epilepsy

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Author :
Publisher : Elsevier
ISBN 13 : 1483291448
Total Pages : 425 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Neurotransmitters in Epilepsy by : Giuliano Avanzini

Download or read book Neurotransmitters in Epilepsy written by Giuliano Avanzini and published by Elsevier. This book was released on 1992-10-08 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Female Brain

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Author :
Publisher : CRC Press
ISBN 13 : 1466574429
Total Pages : 224 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis The Female Brain by : Cynthia L. Darlington

Download or read book The Female Brain written by Cynthia L. Darlington and published by CRC Press. This book was released on 2003-08-29 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ironically, the organ with the greatest reason to differ between the sexes, the brain, is often viewed as the most androgynous of all. Are there differences? Almost by convention, male animals are used in laboratory experiments in neuroscience. Even in clinical drug trials in humans, females are often excluded from the early phases of testing becau

The Neurochemical Basis of Autism

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Author :
Publisher : Springer
ISBN 13 : 9781489981974
Total Pages : 0 pages
Book Rating : 4.9/5 (819 download)

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Book Synopsis The Neurochemical Basis of Autism by : Gene J. Blatt

Download or read book The Neurochemical Basis of Autism written by Gene J. Blatt and published by Springer. This book was released on 2014-12-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A perceived rise in autism worldwide has led to a dramatic increase in autism research. This is a uniquely interdisciplinary text that presents the latest findings regarding the physiological, neuropathological, neurochemical and clinical elements of autism.