Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis

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Author :
Publisher : Biota Publishing
ISBN 13 : 1615040404
Total Pages : 77 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis by : Rolando E. Rumbaut

Download or read book Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis written by Rolando E. Rumbaut and published by Biota Publishing. This book was released on 2010-02-01 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions.

Platelet-Vessel Wall Interactions

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1447114558
Total Pages : 205 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Platelet-Vessel Wall Interactions by : R. Michael Pittilo

Download or read book Platelet-Vessel Wall Interactions written by R. Michael Pittilo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of Platelet-Vessel Wall Interactions, the second monograph in the Bloomsbury Series in Clinical Science, is particu larly welcome as its appearance signifies the further development of the Series and its potential for the future. The theme of this monograph is the pathophysiology of atherosclerosis, a topic that symbolises the aim of the Series, namely to highlight the important interfaces between basic medical science and clinical practice. Our congratulations to the Editors and contributors. London, December 1987 lack Tinker Preface In the Western world, atherosclerosis causes more illness and death than any other disease. Despite its devastating effects, the pathogenesis of the disease remains a matter for hypothesis and con jecture. This monograph owes its conception to a programme of work directed towards understanding the basic pathophysiology of atherosclerosis. The circulatory system is lined by vascular endothelium which has a central role in maintaining the integrity of the vessel wall and prevent ing thrombosis. The natural equilibrium existing between normal en dothelium which supports blood flow, and platelets which serve to re pair damaged endothelium, is explored in the first two chapters. Atherosclerosis developing as a response to endothelial injury is one hypothesis which has stimulated widespread interest, and re search has largely been directed towards finding the injurious agent.

Platelets, Thrombosis and the Vessel Wall

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Author :
Publisher : CRC Press
ISBN 13 : 0203304322
Total Pages : 471 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Platelets, Thrombosis and the Vessel Wall by : Michael C Berndt

Download or read book Platelets, Thrombosis and the Vessel Wall written by Michael C Berndt and published by CRC Press. This book was released on 2003-09-02 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets, Thrombosis and the Vessel Wall aims to highlight the key areas of platelet function in the regulation of haemostasis and thrombosis and covers areas such as platelet production, interaction of platelets with leucocytes, mechanisms of cross-talk between platelets, leukocytes, and endothelium. The two major clinical causes of thrombosis, anti-phospholipid antibodies and genetic predisposition, are also addressed.

Advances in Hemostasis and Thrombosis

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Publisher : Springer Science & Business Media
ISBN 13 : 1461594243
Total Pages : 330 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Advances in Hemostasis and Thrombosis by : A. Cajozzo

Download or read book Advances in Hemostasis and Thrombosis written by A. Cajozzo and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: A greater knowledge of the basic molecular mechanisms which regulate platelet function, coagulation, the fibrinolytic system and their interaction with the vessel wall has allowed a better understanding of the numerous aspects involved in the pathogenesis of thrombosis and the regulation of hemostasis. Thrombosis represents today one of the causes of death in the Western hemisphere. Arterial thrombosis may lead to myocardial infarction, cerebral and peripheral vascular diseases. Venous thrombosis, on the other hand, is a complication of heart disease, surgery, extensive trauma, several obstetric pathologies, and may, at times, develop in apparently healthy subjects. These complex problems are dealt with within the content of "Advances in Hemostasis and Thrombosis." The present papers contain up-to-date information on hemostasis, the role of prostaglandins, fibrinolytic coagulation, rheology, and modern therapeutic approaches along with their clinical application. This book, therefore, offers the reader the opportunity to profit from a rare encounter, an interdisciplinary cooperation, with scientific contributions from numerous countries.

Biology and Pathology of Platelet-vessel Wall Interactions

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Author :
Publisher :
ISBN 13 :
Total Pages : 452 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Biology and Pathology of Platelet-vessel Wall Interactions by : Georges Jolles

Download or read book Biology and Pathology of Platelet-vessel Wall Interactions written by Georges Jolles and published by . This book was released on 1986 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mechanisms of Vascular Disease

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Author :
Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Platelet-Vessel Wall Interactions

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Publisher : Springer
ISBN 13 : 9783540174882
Total Pages : 198 pages
Book Rating : 4.1/5 (748 download)

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Book Synopsis Platelet-Vessel Wall Interactions by : R. Michael Pittilo

Download or read book Platelet-Vessel Wall Interactions written by R. Michael Pittilo and published by Springer. This book was released on 1988-02-26 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of Platelet-Vessel Wall Interactions, the second monograph in the Bloomsbury Series in Clinical Science, is particu larly welcome as its appearance signifies the further development of the Series and its potential for the future. The theme of this monograph is the pathophysiology of atherosclerosis, a topic that symbolises the aim of the Series, namely to highlight the important interfaces between basic medical science and clinical practice. Our congratulations to the Editors and contributors. London, December 1987 lack Tinker Preface In the Western world, atherosclerosis causes more illness and death than any other disease. Despite its devastating effects, the pathogenesis of the disease remains a matter for hypothesis and con jecture. This monograph owes its conception to a programme of work directed towards understanding the basic pathophysiology of atherosclerosis. The circulatory system is lined by vascular endothelium which has a central role in maintaining the integrity of the vessel wall and prevent ing thrombosis. The natural equilibrium existing between normal en dothelium which supports blood flow, and platelets which serve to re pair damaged endothelium, is explored in the first two chapters. Atherosclerosis developing as a response to endothelial injury is one hypothesis which has stimulated widespread interest, and re search has largely been directed towards finding the injurious agent.

Platelets in Thrombotic and Non-Thrombotic Disorders

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Author :
Publisher : Springer
ISBN 13 : 3319474626
Total Pages : 1445 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Platelets in Thrombotic and Non-Thrombotic Disorders by : Paolo Gresele

Download or read book Platelets in Thrombotic and Non-Thrombotic Disorders written by Paolo Gresele and published by Springer. This book was released on 2017-03-08 with total page 1445 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.

Anesthetic Pharmacology

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Publisher : Cambridge University Press
ISBN 13 : 1139497022
Total Pages : 2902 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Anesthetic Pharmacology by : Alex S. Evers

Download or read book Anesthetic Pharmacology written by Alex S. Evers and published by Cambridge University Press. This book was released on 2011-03-10 with total page 2902 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

BLOOD VESSEL WALL & THROMBOSIS

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Author :
Publisher : Springer
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis BLOOD VESSEL WALL & THROMBOSIS by : Raymund Machovich

Download or read book BLOOD VESSEL WALL & THROMBOSIS written by Raymund Machovich and published by Springer. This book was released on 1988-02-29 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Anatomy & Physiology

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Publisher :
ISBN 13 : 9781955101158
Total Pages : pages
Book Rating : 4.1/5 (11 download)

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Book Synopsis Anatomy & Physiology by : Lindsay Biga

Download or read book Anatomy & Physiology written by Lindsay Biga and published by . This book was released on 2019-09-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A version of the OpenStax text

Manual of Blood Platelets: Morphology, Physiology and Pharmacology

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Author :
Publisher : Jaypee Brothers Medical Publishers
ISBN 13 : 9352702026
Total Pages : 283 pages
Book Rating : 4.3/5 (527 download)

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Book Synopsis Manual of Blood Platelets: Morphology, Physiology and Pharmacology by : Gundu HR Rao

Download or read book Manual of Blood Platelets: Morphology, Physiology and Pharmacology written by Gundu HR Rao and published by Jaypee Brothers Medical Publishers. This book was released on 2018-11-30 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets are tiny blood cells that help the body form clots to stop bleeding. Antiplatelet medications, such as aspirin and clopidogrel, are commonly used to thin the blood which limits clotting and reduces the risk of heart attack. This book is a comprehensive guide to blood platelets for haematologists. Beginning with discussion on platelet structure, morphology, function and physiology, the next chapters cover the role of calcium in platelet activation and calcium modulation by cyclic nucleotides. The following sections explain the pharmacology of antiplatelet drugs, antiplatelet therapies, aspirin resistance, and the association of diabetes mellitus with major platelet dysfunction. The book concludes with chapters on acute coronary problems, interaction between endothelial cells and platelets, and blood biocompatibility studies. Authored by a Minneapolis-based expert in the field, the text is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to blood platelets for haematologists Extensive coverage of antiplatelet drugs and resistance Recognised author from University of Minnesota Highly illustrated with clinical photographs, diagrams and tables

Modern Hematology

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Publisher : Springer Science & Business Media
ISBN 13 : 1597451495
Total Pages : 498 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Modern Hematology by : Reinhold Munker

Download or read book Modern Hematology written by Reinhold Munker and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, Modern Hematology: Biology and Clinical Management reflects the major advances in the understanding, diagnosis, and treatment of blood disorders. It describes the latest clinical and scientific developments as well as details targeted and molecular therapies. The book brings together facts, concepts, and protocols important for the practice of hematology. In 23 chapters, all major blood diseases are covered, as well as rare diseases that are of scientific interest. As in the previous edition, each chapter is illustrated by tables, figures, and a selection of color plates.

Pediatric Hematology

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Publisher : Cambridge University Press
ISBN 13 : 1107439361
Total Pages : 299 pages
Book Rating : 4.1/5 (74 download)

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Book Synopsis Pediatric Hematology by : Robert Wynn

Download or read book Pediatric Hematology written by Robert Wynn and published by Cambridge University Press. This book was released on 2017-02-16 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: A succinct summary of the key principles and facts that guide the everyday practice of modern, clinical paediatric hematology. Covering all the information necessary for examinations in the topic, this book is ideal for postgraduates studying paediatric hematology, as well as for junior doctors in training.

Thrombosis and Hemorrhage

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 078173066X
Total Pages : 1190 pages
Book Rating : 4.7/5 (817 download)

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Book Synopsis Thrombosis and Hemorrhage by : Joseph Loscalzo

Download or read book Thrombosis and Hemorrhage written by Joseph Loscalzo and published by Lippincott Williams & Wilkins. This book was released on 2003 with total page 1190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its Third Edition, this authoritative text continues to provide a comprehensive and systematic review of the biology, pathobiology, and clinical disorders of the hemostatic system. Its unique organization of the basic sciences coupled with clinical sections yields a user-friendly integrated text, and a reference tool that meets the needs of diverse investigators and clinicians of contemporary medicine for understanding the hemostatic system. New chapter topics covered in this edition include angiogenesis and vasculogenesis; hemorrhagic complications of antithrombotic therapy; interactions of coagulation and fibrinolytic proteins with the vessel wall; and less common thrombotic disorders.

The Endothelium

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Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041230
Total Pages : 309 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Endothelium by : Michel Félétou

Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

Anatomy and Physiology

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Author :
Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: