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Plasticity And Function Of Human Skeletal Muscle In Realation To Disuse And Rehabilitation Influence Of Ageing And Surgery
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Download or read book Muscle Atrophy written by Junjie Xiao and published by Springer. This book was released on 2018-11-02 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book’s fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scientists, undergraduate and graduate students in medicine and cell biology.
Book Synopsis Muscle Mechanics, Extracellular Matrix, Afferentation, Structural and Neurological Coupling and Coordination in Health and Disease by : Can A. Yucesoy
Download or read book Muscle Mechanics, Extracellular Matrix, Afferentation, Structural and Neurological Coupling and Coordination in Health and Disease written by Can A. Yucesoy and published by Frontiers Media SA. This book was released on 2022-01-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disclosure statement: Topic Editor Prof. Silvia Salinas Blemker is a Co-founder and Vice President of Springbok, Inc. Charlottesville, VA. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Book Synopsis Managing Parkinson's Disease With a Multidisciplinary Perspective by : Daniel Martinez-Ramirez
Download or read book Managing Parkinson's Disease With a Multidisciplinary Perspective written by Daniel Martinez-Ramirez and published by Frontiers Media SA. This book was released on 2022-01-13 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Skeletal Muscle Structure, Function, and Plasticity by : Richard L. Lieber
Download or read book Skeletal Muscle Structure, Function, and Plasticity written by Richard L. Lieber and published by Lippincott Williams & Wilkins. This book was released on 2002 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its Second Edition, this text addresses basic and applied physiological properties of skeletal muscle in the context of the physiological effects from clinical treatment. Many concepts are expanded and recent studies on human muscle have been added. This new edition also includes more clinically relevant cases and stories. A two-page full color insert of muscle sections is provided to ensure integral understanding of the concepts presented in the text. Anyone interested in human movement analysis and the understanding of generation and control from the musculoskeletal and neuromuscular systems in implementing movement will find this a valuable resource.
Book Synopsis The Molecular Nutrition of Amino Acids and Proteins by : Dominique Dardevet
Download or read book The Molecular Nutrition of Amino Acids and Proteins written by Dominique Dardevet and published by Academic Press. This book was released on 2016-06-08 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Molecular Nutrition of Amino Acids and Proteins provides an in-depth look at the involvement and role of amino acids and proteins in molecular nutrition. Editor Dominique Dardevet has assembled a collection of chapters written by leading researchers and top professors that provide the reader with a comprehensive understanding of amino acids and proteins. The book provides an introduction to the fundamentals of amino acids and proteins as well as the composition of food. It then delves into the molecular biology of the cell and genetic machinery and its function. The Molecular Nutrition of Amino Acids and Proteins also features reference guides for terms and bullet-point summaries, making it readily accessible to novices while still providing the most up-to-date and detailed information that experienced researchers need. Provides a gentle introduction to the subject by first addressing nutritional information and then building in molecular aspects, clearly establishing fundamental information for the reader Facilitates reader comprehension by including succinct summary points in each chapter Contains a glossary of definitions that allows readers to easily reference terms Provides both a deep and broad understanding of the subject by containing overviews as well as detail-focused chapters
Book Synopsis Enabling America by : Institute of Medicine
Download or read book Enabling America written by Institute of Medicine and published by National Academies Press. This book was released on 1997-11-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most recent high-profile advocate for Americans with disabilities, actor Christopher Reeve, has highlighted for the public the economic and social costs of disability and the importance of rehabilitation. Enabling America is a major analysis of the field of rehabilitation science and engineering. The book explains how to achieve recognition for this evolving field of study, how to set priorities, and how to improve the organization and administration of the numerous federal research programs in this area. The committee introduces the "enabling-disability process" model, which enhances the concepts of disability and rehabilitation, and reviews what is known and what research priorities are emerging in the areas of: Pathology and impairment, including differences between children and adults. Functional limitationsâ€"in a person's ability to eat or walk, for example. Disability as the interaction between a person's pathologies, impairments, and functional limitations and the surrounding physical and social environments. This landmark volume will be of special interest to anyone involved in rehabilitation science and engineering: federal policymakers, rehabilitation practitioners and administrators, researchers, and advocates for persons with disabilities.
Book Synopsis Bioactive Substances-Mediated Targeted Therapy of Cardio-Cerebrovascular Diseases by : Guixue Wang
Download or read book Bioactive Substances-Mediated Targeted Therapy of Cardio-Cerebrovascular Diseases written by Guixue Wang and published by Frontiers Media SA. This book was released on 2023-03-07 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Download or read book Research Awards Index written by and published by . This book was released on 1987 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Isotope Tracers in Metabolic Research by : Robert R. Wolfe
Download or read book Isotope Tracers in Metabolic Research written by Robert R. Wolfe and published by John Wiley & Sons. This book was released on 2004-10-18 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few years, the number of applications of tracers for in vivo biomedical studies has greatly increased. New analytical tools at the genetic and protein levels have spurred this growth, opening the door for a deeper understanding of metabolic events. This in turn promises to yield significant advances in the understanding and treatment of human disease. Now fully revised and expanded, Isotope Tracers in Metabolic Research, Second Edition is the established definitive text on stable and radioactive isotope tracers. In unique, multidisciplinary fashion, it presents comprehensive coverage of new methodological, mathematical, and theoretical approaches. This new Second Edition includes: All-new chapters on nuclear magnetic resonance, mass isotopomer analysis, and methods of protein metabolism analysis A completely updated categorized list of over 750 references Major advances in the development of mass isotopomer and positional isotopomer techniques, noninvasive isotope techniques for studying metabolic pathways, hyphenated techniques, and new tracer techniques The latest developments in quantification of DNA synthesis and mass spectrometry spurred by genome sequencing and proteomics New coverage of mathematical modeling Expanded coverage of microdialysis probes, laboratory procedures, and regulatory issues related to human studies In this complete guide to performing tracer studies, the authors systematically cover tracer selection, modeling considerations, sample derivitization, mass spectrometry analysis, and data interpretation. Problems and discussion questions highlight key points in each chapter. Isotope Tracers in Metabolic Research, Second Edition offers students and researchers a comprehensive, practical resource for utilizing the latest tracer methodologies.
Book Synopsis Brain Repair After Stroke by : Steven C. Cramer
Download or read book Brain Repair After Stroke written by Steven C. Cramer and published by Cambridge University Press. This book was released on 2010-10-28 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.
Book Synopsis Skeletal Muscle Damage and Repair by : Peter M. Tiidus
Download or read book Skeletal Muscle Damage and Repair written by Peter M. Tiidus and published by Human Kinetics. This book was released on 2008 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Attempts to cover a wide range of both basic research and applied clinical topics related to skeletal muscle damage and repair mechanisms and their application. This book examines muscle damage and repair mechanisms and issues in specific populations including older adults and special populations.
Book Synopsis Rehabilitation of Musculoskeletal Injuries by : Peggy A. Houglum
Download or read book Rehabilitation of Musculoskeletal Injuries written by Peggy A. Houglum and published by Human Kinetics. This book was released on 2022-10-24 with total page 1178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rehabilitation of Musculoskeletal Injuries, Fifth Edition With HKPropel Online Video, presents foundational concepts that support a thorough understanding of therapeutic interventions and rehabilitative techniques. Updated with the latest research in evidence-based practice, this text prepares students for careers in health care while serving as a valuable reference for experienced clinicians. Readers will learn what to expect when treating clients, how to apply evidence-based knowledge, and how to customize individual rehab programs. Related online video demonstrates 47 of the most challenging or novel techniques and can be used in the classroom or in everyday practice. Titled Therapeutic Exercise for Musculoskeletal Injuries in previous editions, the revised title supports the advancement of the field and better reflects the concepts and understanding of total rehabilitation of the patient. The content featured in Rehabilitation of Musculoskeletal Injuries aligns with the accreditation standards of the Board of Certification (BOC) and prepares students for the BOC athletic trainers’ exam. Respected clinician Peggy A. Houglum, who has more than 50 years of experience in the field, leads the expert author team to provide evidence-based perspectives, updated theories, and real-world applications. The latest edition is enhanced with contributions from new authors Daniel E. Houglum and Kristine L. Boyle-Walker, who have over 54 combined years of experience as athletic trainers, physical therapists, and instructors. The fifth edition of Rehabilitation of Musculoskeletal Injuries places a greater emphasis on higher-order skills. Although it continues to present therapeutic exercise interventions, added content includes the other aspects of rehabilitation that would be applied to patients in clinical situations, including therapeutic interventions of modalities. Specific aspects of examination that are necessary to designing a rehabilitation program are also included. This edition also includes a new section on joint manipulation and a new chapter on functional adaptations in rehabilitation that focuses on providing emotional support as well as physical support in helping patients return to activities of daily living. Video content is expanded with 11 new clips that highlight therapeutic techniques, and more than 450 color photos and 750 illustrations help to enhance comprehension and clarify complicated concepts. Rehabilitation of Musculoskeletal Injuries, Fifth Edition, provides thorough coverage of healing concepts, examination, and assessment techniques, ensuring students move from a solid understanding of the foundational skills and knowledge required of clinicians to comprehension of advanced problem-solving skills to make reliable rehabilitation decisions. The text demonstrates how to create rehabilitation programs using various modalities, manual therapy, and therapeutic exercise, and it highlights special considerations and applications for specific body regions. Learning aids include case studies that emphasize practical application, Evidence in Rehabilitation sidebars that focus on peer-reviewed research and its practical application, and Clinical Tips that illustrate key points in each chapter. Additional learning aids include chapter objectives, lab activities, key terms, critical thinking questions, and references. For maximum flexibility to match course needs, instructors wanting to teach specific topics can adopt particular chapters or sections of the book through the Human Kinetics custom ebook program. Note: A code for accessing online videos is not included with this ebook but may be purchased separately.
Book Synopsis Clinical Pathways in Stroke Rehabilitation by : Thomas Platz
Download or read book Clinical Pathways in Stroke Rehabilitation written by Thomas Platz and published by Springer Nature. This book was released on 2021-01-14 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on practical clinical problems that are frequently encountered in stroke rehabilitation. Consequences of diseases, e.g. impairments and activity limitations, are addressed in rehabilitation with the overall goal to reduce disability and promote participation. Based on the available best external evidence, clinical pathways are described for stroke rehabilitation bridging the gap between clinical evidence and clinical decision-making. The clinical pathways answer the questions which rehabilitation treatment options are beneficial to overcome specific impairment constellations and activity limitations and are well acceptable to stroke survivors, as well as when and in which settings to provide rehabilitation over the course of recovery post stroke. Each chapter starts with a description of the clinical problem encountered. This is followed by a systematic, but concise review of the evidence (RCTs, systematic reviews and meta-analyses) that is relevant for clinical decision-making, and comments on assessment, therapy (training, technology, medication), and the use of technical aids as appropriate. Based on these summaries, clinical algorithms / pathways are provided and the main clinical-decision situations are portrayed. The book is invaluable for all neurorehabilitation team members, clinicians, nurses, and therapists in neurology, physical medicine and rehabilitation, and related fields. It is a World Federation for NeuroRehabilitation (WFNR) educational initiative, bridging the gap between the rapidly expanding clinical research in stroke rehabilitation and clinical practice across societies and continents. It can be used for both clinical decision-making for individuals and as well as clinical background knowledge for stroke rehabilitation service development initiatives.
Book Synopsis The Unfolded Protein Response by : Roberto Pérez Torrado
Download or read book The Unfolded Protein Response written by Roberto Pérez Torrado and published by . This book was released on 2022 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is divided in six section covering the most experimental approaches involved in the study of the unfolded protein response (UPR) pathway. Chapters detail determination of unfolded protein levels, methods to study UPR signal transmission, analysing the outcomes of the UPR pathway activation, UPR studies in mammalian models, UPR in alternative models, and UPR and disease. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, The Unfolded Protein Response: Methods and Protocols aims to describe key methods and approaches used in the study of the UPR pathway and its complex cellular implications. Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Book Synopsis Multiple Sclerosis by : Institute of Medicine
Download or read book Multiple Sclerosis written by Institute of Medicine and published by National Academies Press. This book was released on 2001-08-10 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.
Book Synopsis Anti-ageing Medicine by : Astrid Stuckelberger
Download or read book Anti-ageing Medicine written by Astrid Stuckelberger and published by vdf Hochschulverlag AG. This book was released on 2008 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 21st century technological development is revolutionizing medicine and health care, bringing new hopes to human suffering by offering cures and treatments which were unthinkable a few decades ago. This is where anti-ageing medicine finds its niche. Anti-ageing medicine aims at slowing, arresting, and reversing phenomena associated with ageing by merging biotechnological innovation and engineered solutions. Ideally, by means of the newest medical technology, the "body machinery" should be kept fit and at peak performance all life long. Early detection of age-related dysfunction should thus be "fixed" at any age with interventions such as metabolic fine tuning, enhancement, regeneration, restoration or replacement of "body parts" (i.e. organs, skin, bone or muscle). It covers a vast array of domains: from cell therapy to pharmaceutical interventions, from bio-surgery to aesthetic surgery, from human enhancement to fortified food, from smart housing and robots to toxic-free environments. Anti-ageing medicine holds promises but also significant risks and safety issues which are addressesd in this book. It presents the latest scientific evidence on what works or does not work. It also provides public policy recommendations to ensure the protection of consumers and their rights while encouraging research and development. This book is intended for academics, health professionals, business persons, consumers and policy-makers interested in the latest evidence and ethical issues about anti-ageing medicine.