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Plasma Mass Spectrometric Detection For High Performance Liquid Chromatography
Download Plasma Mass Spectrometric Detection For High Performance Liquid Chromatography full books in PDF, epub, and Kindle. Read online Plasma Mass Spectrometric Detection For High Performance Liquid Chromatography ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Elemental Speciation by : Joseph A. Caruso
Download or read book Elemental Speciation written by Joseph A. Caruso and published by Elsevier Science Limited. This book was released on 2000 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. This book provides a comprehensive discussion of the major aspects involved in elemental speciation. Sample preparation, separation techniques, instrumentation and quality assurance are all discussed. In addition, individual chapters are devoted to speciation of environmental samples and speciation of biological, clinical, and nutritional samples. Individual chapters are written by leaders in the field, and the book has been organized so that the reader may learn how to collect a sample and prepare it. Ways to separate and detect analytes of interest, and steps to take to ensure the validity of the measurements are also discussed. This book is unique in its comprehensive treatment of this subject.
Book Synopsis Principles of Bioinorganic Chemistry by : Stephen J. Lippard
Download or read book Principles of Bioinorganic Chemistry written by Stephen J. Lippard and published by University Science Books. This book was released on 1994 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of unnatural metals - which have been introduced into human biology as diagnostic probes and drugs - is another active area of tremendous medical significance.
Download or read book Arsenic Speciation in Algae written by and published by Elsevier. This book was released on 2019-06-07 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arsenic Speciation in Algae, Volume 85, addresses the most important issues to consider during arsenic speciation in algae, including new sections on Occurrence, distribution, and significance of arsenic speciation, Biogeochemistry of arsenic in aquatic environments: the role of speciation, Sampling and sampling processing: fit for purpose techniques, Separation methods applied to arsenic speciation, Detection and quantification of arsenic compounds, Analytical approaches for proteomics and lipidomics of arsenic in algae, Quality control and quality assurance issues in arsenic speciation, Arsenic speciation in algae: case studies in Europe, and more. - Features the latest content combined with the experience of our distinguished contributors
Book Synopsis Metabolic Profiling by : Georgios A. Theodoridis
Download or read book Metabolic Profiling written by Georgios A. Theodoridis and published by Humana. This book was released on 2019-04-30 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the different approaches and techniques used by researchers to study the recent challenges and developments in metabolic profiling. This book is divided into IV parts. Part I contains chapters that highlight basic concepts, such as experimental design, data treatment, metabolite identification, and harmonization. Part II describes experimental protocols for both targeted and untargeted metabolomics covering the basic analytical technologies: LC-MS, GC-MS, NMR and CE-MS. In addition the protocols describe methods for the study of tissues, feces, blood and other types of biological samples as well as the application of chemical derivatization for GC-MS. Parts III and IV present the use of metabolomics in the study of food, plants and the life sciences, with examples from the quest for the discovery of disease biomarkers, physical exercise omics and metabolic profiling of food, fruit and wine. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Metabolic Profiling: Methods and Protocols is a valuable resource for researchers who are interested in expanding their knowledge of this rapidly developing field.
Book Synopsis Chiral Liquid Chromatography by : w Lough
Download or read book Chiral Liquid Chromatography written by w Lough and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: While working as a chromatographer in the pharmaceutical industry, it became apparent to the editor that there was a pressing need for a comprehensive reference text for analysts working on the resolution of enantiomers by liquid chromatography (LC). This need arises from the fact that, whereas previously it was very difficult to determine enantiomers by direct means, there is now a wide choice of direct LC methods. At the same time, regulatory authorities have been changing their attitudes towards the administration of pharmaceuticals as racemates, partly because it is now possible to study the individual enantiomers. Clearly this abundance of new information needs to be rationalized. More importantly, the chiral LC systems which are commercially available or readily accessible to the practising chromatographer needed to be reviewed and, to a much greater extent than in existing reviews or books, discussed in terms of their practical application. Accordingly this book is very much orientated towards the practical aspects of these commercially available and readily accessible chiral LC systems. To this end, it is written for practising chromatographers by a team of practising, experienced chromatographers who have spent many years tackling the problems presented by resolving enantiomers by LC. The practical aspects of common chiral LC systems cannot be fully understood if discussed in isolation.
Book Synopsis Liquid Chromatography by : Salvatore Fanali
Download or read book Liquid Chromatography written by Salvatore Fanali and published by Elsevier. This book was released on 2017-06-23 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liquid Chromatography: Applications, Second Edition,is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their knowledge of the wide variety of applications in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. - Emphasizes the integration of chromatographic methods and sample preparation - Explains how liquid chromatography is used in different industrial sectors - Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) - Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making
Book Synopsis Techniques in Protein Chemistry III by : Ruth Hogue Angeletti
Download or read book Techniques in Protein Chemistry III written by Ruth Hogue Angeletti and published by Academic Press. This book was released on 2014-06-28 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: Techniques in Protein Chemistry III compiles papers presented at the Fifth Protein Society Symposium in Baltimore on June 22-26, 1991. This book discusses the protein and peptide recovery from PVDF membranes; high-sensitivity peptide mapping utilizing reversed-phase microbore and microcolumn liquid chromatography; and capillary electrophoresis for preparation of peptides and direct determination of amino acids. The TFMSA/TFA cleavage in t-Boc peptide synthesis; applications of automatic PTC amino acid analysis; and identification of O-glycosylation sites with a gas phase sequencer are also elaborated. This text likewise covers the conformational stability of the molten globule of cytochrome c and role of aqueous solvation in protein folding. This publication is useful to students and researchers interested in methods and research approaches on protein chemistry.
Book Synopsis Ultra Performance Liquid Chromatography Mass Spectrometry by : Mu Naushad
Download or read book Ultra Performance Liquid Chromatography Mass Spectrometry written by Mu Naushad and published by CRC Press. This book was released on 2014-03-18 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a unique collection of up-to-date UPLC-MS/MS (ultra performance liquid chromatography-tandem mass spectrometric) methods for the separation and quantitative determination of pesticides, capsaicinoids, heterocyclic amines, aflatoxin, perfluorochemicals, acrylamide, procyanidins and alkaloids, lactose content, phenolic compounds, vitamins, and aroma and flavor compounds in a wide variety of foods and food products. With contributions by experts in interdisciplinary fields, this reference offers practical information for readers in research and development, production, and routing analysis of foods and food products.
Book Synopsis Chemical Processes in Marine Environments by : Antonio Gianguzza
Download or read book Chemical Processes in Marine Environments written by Antonio Gianguzza and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses recent developments in the study of chemical processes and equilibria in the marine environment and in the air/water and water/sediment interfaces. The chemical cycle of carbon as well as the effect of organic substances on the speciation and distribution of inorganic and organometallic substances are extensively discussed. Much of the recent progress in the area is the direct result of advanced analytical technologies and chemometric applications which are highlighted in the book.
Book Synopsis Handbook of Radioactivity Analysis by : Michael F. L'Annunziata
Download or read book Handbook of Radioactivity Analysis written by Michael F. L'Annunziata and published by Elsevier. This book was released on 2012-12-02 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Radioactivity Analysis is written by experts in the measurement of radioactivity. The book describes the broad scope of analytical methods available and instructs the reader on how to select the proper technique. It is intended as a practical manual for research which requires the accurate measurement of radioactivity at all levels, from the low levels encountered in the environment to the high levels measured in radioisotope research. This book contains sample preparation procedures, recommendations on steps to follow, necessary calculations, computer controlled analysis, and high sample throughput techniques. Each chapter includes practical techniques for application to nuclear safety, nuclear safeguards, environmental analysis, weapons disarmament, and assays required for research in biomedicine and agriculture. The fundamentals of radioactivity properties, radionuclide decay, and methods of detection are included to provide the basis for a thorough understanding of the analytical procedures described in the book. Therefore, the Handbook can also be used as a teaching text. - Includes sample preparation techniques for matrices such as soil, air, plant, water, animal tissue, and surface swipes - Provides procedures and guidelines for the analysis of commonly encountered na
Book Synopsis Introduction to Drug Metabolism by : G. Gordon Gibson
Download or read book Introduction to Drug Metabolism written by G. Gordon Gibson and published by Nelson Thornes. This book was released on 2001 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of drug-metabolising reactions. p. 25.
Book Synopsis Proteomic and Metabolomic Approaches to Biomarker Discovery by : Haleem J. Issaq
Download or read book Proteomic and Metabolomic Approaches to Biomarker Discovery written by Haleem J. Issaq and published by Academic Press. This book was released on 2013-05-20 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research. - Describes the use of biomarkers to reduce clinical errors in research - Includes techniques from a range of biomarker discoveries - Covers all steps involved in biomarker discovery, from study design to study execution
Book Synopsis Integrated Strategies for Drug Discovery Using Mass Spectrometry by : Mike S. Lee
Download or read book Integrated Strategies for Drug Discovery Using Mass Spectrometry written by Mike S. Lee and published by John Wiley & Sons. This book was released on 2005-09-02 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: New strategies and techniques for today's fast-paced discoveryprocess Today, the pressure is on for high-throughput approaches toaccelerate the generation, identification, and optimization ofmolecules with desirable drug properties. As traditional methods ofanalysis become antiquated, new analytical strategies andtechniques are necessary to meet sample throughput requirements andmanpower constraints. Among them, mass spectrometry has grown to bea front-line tool throughout drug discovery. Integrated Strategies for Drug Discovery Using Mass Spectrometryprovides a thorough review of current analytical approaches,industry practices, and strategies in drug discovery. The topicsrepresent current industry benchmarks in specific drug discoveryactivities that deal with proteomics, biomarker discovery,metabonomic approaches for toxicity screening, lead identification,compound libraries, quantitative bioanalytical support,biotransformation, reactive metabolite characterization, leadoptimization, pharmaceutical property profiling, sample preparationstrategies, and automation. THIS BOOK: * Clearly explains how drug discovery and mass spectrometry areinterconnected * Discusses the uses and limitations of various types of massspectrometry in various aspects of drug discovery * Prominently features analytical applications that requiretrace-mixture analysis * Provides industry applications and real-world examples * Shares historical background information on various techniques toaid in the understanding of how and why new methods are now beingemployed to analyze samples
Book Synopsis Tandem Mass Spectrometry by : Ana Varela Coelho
Download or read book Tandem Mass Spectrometry written by Ana Varela Coelho and published by BoD – Books on Demand. This book was released on 2013-05-29 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tandem Mass Spectrometry - Molecular Characterization presents a comprehensive coverage of theory, instrumentation and description of experimental strategies and MS/MS data interpretation for the structural characterization of relevant molecular compounds. The areas covered include the analysis of drugs, metabolites, carbohydrates and protein post-translational modifications. The book series in Tandem Mass Spectrometry serves multiple groups of audiences; professional (academic and industry), graduate students and general readers interested in the use of modern mass spectrometry in solving critical questions of chemical and biological sciences.
Book Synopsis Planar Chromatography - Mass Spectrometry by : Teresa Kowalska
Download or read book Planar Chromatography - Mass Spectrometry written by Teresa Kowalska and published by CRC Press. This book was released on 2015-11-18 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Planar Chromatography-Mass Spectrometry focuses on a relatively new approach to chemical analysis in general, and to separation science in particular. It is the first book to systemically cover the theoretical background, techniques, instrumentation, and practical applications of planar chromatography-mass spectrometry as a hyphenated tool of analy
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Book Synopsis Sample Preparation in LC-MS Bioanalysis by : Wenkui Li
Download or read book Sample Preparation in LC-MS Bioanalysis written by Wenkui Li and published by John Wiley & Sons. This book was released on 2019-03-12 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revised and Expanded Handbook Provides Comprehensive Introduction and Complete Instruction for Sample Preparation in Vital Category of Bioanalysis Following in the footsteps of the previously published Handbook of LC-MS Bioanalysis, this book is a thorough and timely guide to all important sample preparation techniques used for quantitative Liquid Chromatography–Mass Spectrometry (LC-MS) bioanalysis of small and large molecules. LC-MS bioanalysis is a key element of pharmaceutical research and development, post-approval therapeutic drug monitoring, and many other studies used in human healthcare. While advances are continually being made in key aspects of LC-MS bioanalysis such as sensitivity and throughput, the value of research/study mentioned above is still heavily dependent on the availability of high-quality data, for which sample preparation plays the critical role. Thus, this text provides researchers in industry, academia, and regulatory agencies with detailed sample preparation techniques and step-by-step protocols on proper extraction of various analyte(s) of interest from biological samples for LC-MS quantification, in accordance with current health authority regulations and industry best practices. The three sections of the book with a total of 26 chapters cover topics that include: Current basic sample preparation techniques (e.g., protein precipitation, liquid-liquid extraction, solid-phase extraction, salting-out assisted liquid-liquid extraction, ultracentrifugation and ultrafiltration, microsampling, sample extraction via electromembranes) Sample preparation techniques for uncommon biological matrices (e.g., tissues, hair, skin, nails, bones, mononuclear cells, cerebrospinal fluid, aqueous humor) Crucial aspects of LC-MS bioanalytical method development (e.g., pre-analytical considerations, derivation strategies, stability, non-specific binding) in addition to sample preparation techniques for challenging molecules (e.g., lipids, peptides, proteins, oligonucleotides, antibody-drug conjugates) Sample Preparation in LC-MS Bioanalysis will prove a practical and highly valuable addition to the reference shelves of scientists and related professionals in a variety of fields, including pharmaceutical and biomedical research, mass spectrometry, and analytical chemistry, as well as practitioners in clinical pharmacology, toxicology, and therapeutic drug monitoring.
