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Polycystic Kidney Disease

Author : Jinghua Hu
Publisher : CRC Press
ISBN 13 : 0429888945
Total Pages : 360 pages
Book Rating : 4.4/5 (298 download)

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Book Synopsis Polycystic Kidney Disease by : Jinghua Hu

Download or read book Polycystic Kidney Disease written by Jinghua Hu and published by CRC Press. This book was released on 2019-10-24 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the investigatory methods applied to autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. ADPKD is caused by mutations in PKD1 and TRPP2, two integral membrane proteins that function as receptor/ion channels in primary cilia of tubular epithelial cells. Thus, ADPKD belongs to ciliopathies, a group of disorders caused by abnormal cilia formation or function. This proposed book will cover the state-of-the-art methods ranging from molecular biology, biochemistry, electrophysiology, to tools in model animal studies. Key Features Explores the role of cilia in polycystic kidney disease Focuses on myriad state-of-the-art methods and techniques Reviews specific mutations integral to this autosomal genetic disease Includes discussions of model systems

Cystogenesis

Author : Jong Hoon Park
Publisher : Springer
ISBN 13 : 9811020418
Total Pages : 128 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Cystogenesis by : Jong Hoon Park

Download or read book Cystogenesis written by Jong Hoon Park and published by Springer. This book was released on 2016-10-12 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.

Why I Think about Urine

Author : Jared James Grantham
Publisher : Rockhill Books
ISBN 13 : 9781611691283
Total Pages : 282 pages
Book Rating : 4.6/5 (912 download)

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Book Synopsis Why I Think about Urine by : Jared James Grantham

Download or read book Why I Think about Urine written by Jared James Grantham and published by Rockhill Books. This book was released on 2014-04-11 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this page-turner, Dr. Jared Grantham, a noted researcher with the University of Kansas Medical Center, takes the reader through his life of scientific discovery, but a life also of hardship beset by tragedy. It follows a career path that begins in Kansas, finishes in Kansas and ultimately leads to the development of a treatment for a devastating kidney disease suffered by his boyhood friend.

Ferri's Clinical Advisor 2020 E-Book

Author : Fred F. Ferri
Publisher : Elsevier Health Sciences
ISBN 13 : 0323679773
Total Pages : 7615 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Ferri's Clinical Advisor 2020 E-Book by : Fred F. Ferri

Download or read book Ferri's Clinical Advisor 2020 E-Book written by Fred F. Ferri and published by Elsevier Health Sciences. This book was released on 2019-06-01 with total page 7615 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significantly updated with the latest developments in diagnosis and treatment recommendations, Ferri's Clinical Advisor 2020 features the popular "5 books in 1" format to organize vast amounts of information in a clinically relevant, user-friendly manner. This efficient, intuitive format provides quick access to answers on 1,000 common medical conditions, including diseases and disorders, differential diagnoses, and laboratory tests – all reviewed by experts in key clinical fields. Updated algorithms, along with hundreds of new figures, tables, and boxes, ensure that you stay current with today's medical practice. - Contains significant updates throughout, covering all aspects of current diagnosis and treatment. - Features 27 all-new topics including chronic traumatic encephalopathy, medical marijuana, acute respiratory failure, gallbladder carcinoma, shift work disorder, radial tunnel syndrome, fertility preservation in women, fallopian tube cancer, primary chest wall cancer, large-bowel obstruction, inguinal hernia, and bundle branch block, among others. - Includes a new appendix covering Physician Quality Reporting System (PQRS) Measures. - Provides current ICD-10 insurance billing codes to help expedite insurance reimbursements. - Patient Teaching Guides for many of the diseases and disorders are included, most available in both English and Spanish versions, which can be downloaded and printed for patients.

The Man in the High Castle

Author : Philip K. Dick
Publisher : Houghton Mifflin Harcourt
ISBN 13 : 0547572484
Total Pages : 291 pages
Book Rating : 4.5/5 (475 download)

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Book Synopsis The Man in the High Castle by : Philip K. Dick

Download or read book The Man in the High Castle written by Philip K. Dick and published by Houghton Mifflin Harcourt. This book was released on 2011 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Slavery is back. America, 1962. Having lost a war, America finds itself under Nazi Germany and Japan occupation. A few Jews still live under assumed names. The 'I Ching' is prevalent in San Francisco. Science fiction meets serious ideas in this take on a possible alternate history.

The Exegesis of Philip K Dick

Author : Philip K. Dick
Publisher : Houghton Mifflin Harcourt
ISBN 13 : 0547549253
Total Pages : 1003 pages
Book Rating : 4.5/5 (475 download)

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Book Synopsis The Exegesis of Philip K Dick by : Philip K. Dick

Download or read book The Exegesis of Philip K Dick written by Philip K. Dick and published by Houghton Mifflin Harcourt. This book was released on 2011-11-07 with total page 1003 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A great and calamitous sequence of arguments with the universe: poignant, terrifying, ludicrous, and brilliant. The Exegesis is the sort of book associated with legends and madmen, but Dick wasn't a legend and he wasn't mad. He lived among us, and was a genius."-Jonathan Lethem Based on thousands of pages of typed and handwritten notes, journal entries, letters, and story sketches, The Exegesis of Philip K. Dick is the magnificent and imaginative final work of an author who dedicated his life to questioning the nature of reality and perception, the malleability of space and time, and the relationship between the human and the divine. Edited and introduced by Pamela Jackson and Jonathan Lethem, this will be the definitive presentation of Dick's brilliant, and epic, final work. In The Exegesis, Dick documents his eight-year attempt to fathom what he called "2-3-74," a postmodern visionary experience of the entire universe "transformed into information." In entries that sometimes ran to hundreds of pages, Dick tried to write his way into the heart of a cosmic mystery that tested his powers of imagination and invention to the limit, adding to, revising, and discarding theory after theory, mixing in dreams and visionary experiences as they occurred, and pulling it all together in three late novels known as the VALIS trilogy. In this abridgment, Jackson and Lethem serve as guides, taking the reader through the Exegesis and establishing connections with moments in Dick's life and work.

Ubik

Author : Philip K. Dick
Publisher : Houghton Mifflin Harcourt
ISBN 13 : 0547572298
Total Pages : 241 pages
Book Rating : 4.5/5 (475 download)

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Book Synopsis Ubik by : Philip K. Dick

Download or read book Ubik written by Philip K. Dick and published by Houghton Mifflin Harcourt. This book was released on 2012 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: A mind-bending, classic Philip K. Dick novel about the perception of reality. Named as one of Time's 100 best books.

Polycystic Kidney Disease

Author : Benjamin D. Cowley, Jr.
Publisher : Springer
ISBN 13 : 1493977849
Total Pages : 274 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Polycystic Kidney Disease by : Benjamin D. Cowley, Jr.

Download or read book Polycystic Kidney Disease written by Benjamin D. Cowley, Jr. and published by Springer. This book was released on 2018-05-24 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive guide to polycystic kidney disease captures the growing knowledge of this common, potentially-fatal and hereditary disease. The first two sections of the book provide an overview of PKD gene structures, mutations and pathophysiologic mechanisms. This is followed by chapters focused on PKD’s clinical features, including renal and extrarenal manifestations, and appropriate management of patients. The final section covers current clinical trials and emerging therapies in PKD. Authored by experts in the field, this book provides the clinician and researcher with critical information on basic and translational science and clinical approaches in one concise resource.

Vintage PKD

Author : Philip K. Dick
Publisher : Vintage
ISBN 13 : 1400096073
Total Pages : 210 pages
Book Rating : 4.4/5 ( download)

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Book Synopsis Vintage PKD by : Philip K. Dick

Download or read book Vintage PKD written by Philip K. Dick and published by Vintage. This book was released on 2006-06-13 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: A master of science fiction, a voice of the changing counterculture, and a genuine visionary, Philip K. Dick wrote about reality, entropy, deception, and the plight of being alive in the modern world. Through his remarkable career Dick has established himself as a writer of the first order and his dreams of the future have proven to be eerily prophetic and even more prescient than when he wrote them. Vintage PKD features extracts from The Man in the High Castle, The Three Stigmata of Palmer Eldritch, Ubik, A Scanner Darkly, VALIS, and stories including “The Days of Perky Pat,” “A Little Something for Us Tempunauts," and “I Hope I Shall Arrive Soon,” along with essays and letters currently unavailable in book form. Vintage Readers are a perfect introduction to some of the great modern writers, presented in attractive, affordable paperback editions.

Polycystic Kidney Disease

Author : Xiaogang Li
Publisher :
ISBN 13 : 9780994438102
Total Pages : pages
Book Rating : 4.4/5 (381 download)

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Book Synopsis Polycystic Kidney Disease by : Xiaogang Li

Download or read book Polycystic Kidney Disease written by Xiaogang Li and published by . This book was released on 2015-11-17 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Polycystic kidney disease (PKD) is characterized by the presence of fluid-filled cysts in the kidneys. It is the fourth most common cause of chronic renal insufficiency or end-stage kidney disease. This book focuses on the basic and clinical aspects of the burgeoning PKD research under three sections. Section 1 provides a comprehensive guide to the diagnosis, management and treatment of PKD. Section 2 covers most of the fundamental molecular and cellular mechanisms underlying PKD, and how this knowledge is contributing to the development of potential novel therapeutic agents. Finally, section 3 focuses on extra-renal or secondary complications of PKD.

The Cystic Kidney

Author : K.D. Gardner
Publisher : Springer Science & Business Media
ISBN 13 : 9400904576
Total Pages : 441 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis The Cystic Kidney by : K.D. Gardner

Download or read book The Cystic Kidney written by K.D. Gardner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a book about renal cysts and cystic kidneys. Its contributors have created a resource of current information in a field that once aroused only curiosity, but that now stands at the leading edge of molecular nephrology. Its authorship includes 'oldtimers', who bring the wisdom of experience, and 'newcomers', whose presence attests to the contributions made by the investigative and technological advances of the past decade. Its text is organized to carry the reader from renal cyst to cystic renal disease. Each of its chapters defines or explores a challenge or an advance. Cells that line renal cysts are diverse in structure, type, and perhaps function. The cysts themselves lie within an interstitium that is not normal and may influence cyst development and growth. Experimental analogs of human disease offer increasing opportunities to basic researchers to examine, in sequence and under controlled circumstances, those events that favor nephron dilation, cyst growth and ultimate renal failure.

Chronic Kidney Disease

Author : Thomas Rath
Publisher : BoD – Books on Demand
ISBN 13 : 953513843X
Total Pages : 307 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Chronic Kidney Disease by : Thomas Rath

Download or read book Chronic Kidney Disease written by Thomas Rath and published by BoD – Books on Demand. This book was released on 2018-02-21 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Known worldwide, chronic kidney disease (CKD) is a disease that affects up to 4% of the population with increasing figures also in the developing countries. Life expectancy of patients affected by CKD is shortened compared to the overall population, and only a minority of patients reach end-stage renal disease (ESRD) with the need for dialysis or renal transplantation; death overtakes dialysis. In the 13 chapters, this book sheds light on the different aspects related to pathophysiology and clinical aspects of CKD, providing interesting insights into not only inflammation and cardiovascular risk but also the interplay of hormones and the functional aspects of endothelial function. In addition, chapters dealing with genetic aspects of polycystic kidney disease and also the clinical handling of patients with CKD and peritoneal dialysis will be beneficial for the open-minded reader.

Paroxysmal Movement Disorders

Author : Kapil D. Sethi
Publisher : Springer Nature
ISBN 13 : 3030537218
Total Pages : 145 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Paroxysmal Movement Disorders by : Kapil D. Sethi

Download or read book Paroxysmal Movement Disorders written by Kapil D. Sethi and published by Springer Nature. This book was released on 2020-11-18 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the challenges in the differential diagnosis and management of paroxysmal movement disorders. It provides the latest information on the genetics and pathophysiology, neurophysiology and neuroimaging of the core group of disorders in the field, namely the paroxysmal dyskinesias (PxD). Focused and concise, this guide features chapters that discuss other conditions that may be paroxysmal such as, episodic ataxia, startle syndromes and other more complicated groups of paroxysmal movement disorders such as ATP1A3 spectrum disorders. A chapter on secondary (acquired) paroxysmal dyskinesia highlights medical and other disorders that may result in paroxysmal dyskinesia. The book features a particularly nuanced chapter that discusses recent discoveries in the genetic aspects of PxD, relaying that paroxysmal dyskinesias are not channelpathies, but in fact are synaptophies and transportopathies. Additionally, expertly written chapters are supplemented by high quality images, tables, and videos. Paroxysmal Movement Disorders: A Practical Guide is primarily written to educate the reader on how to make a syndromic diagnosis of paroxysmal movement disorders and how to build the diagnostic work-up accordingly, as well as how to manage patients with paroxysmal movement disorders.

Renal Fibrosis: Mechanisms and Therapies

Author : Bi-Cheng Liu
Publisher : Springer
ISBN 13 : 9811388717
Total Pages : 707 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Renal Fibrosis: Mechanisms and Therapies by : Bi-Cheng Liu

Download or read book Renal Fibrosis: Mechanisms and Therapies written by Bi-Cheng Liu and published by Springer. This book was released on 2019-08-09 with total page 707 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD). Due to its high prevalence, CKD represents a huge global economic and social burden. Irrespective of the initial causes, CKD progresses to end stage kidney disease (ESKD) due to renal fibrosis, which is characterized by glomerulosclerosis, tubule atrophy and atresia, and the excessive accumulation of extracellular matrix (ECM) in the kidney. Unfortunately, an estimated 1%-2% of the adult population living with CKD will need renal replacement therapy at some point as a result of ESKD. As such, strategies for preventing or slowing CKD progression to ESKD are of utmost importance, and studies aiming to understand the mechanisms of renal fibrosis have been the focus of intensive research. Recently, novel insights into the pathophysiological processes have furthered our understanding of the pathogenesis of renal fibrosis, and more importantly, promoted studies on the early diagnosis and treatment of CKD. This book draws lessons from the extensive, state-of-the-art research in this field, elaborating the new theories and new techniques to offer readers a detailed and comprehensive understanding of renal fibrosis and as well as inspiration for future research directions.

Cooking Well

Author : Jacob Taylor
Publisher :
ISBN 13 : 9780692705582
Total Pages : pages
Book Rating : 4.7/5 (55 download)

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Book Synopsis Cooking Well by : Jacob Taylor

Download or read book Cooking Well written by Jacob Taylor and published by . This book was released on 2016-06-15 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Cookbook tailored for those with Polycystic Kidney Disease

My New Kidney & Me

Author : Greg Baldauf
Publisher :
ISBN 13 : 9781643439822
Total Pages : 0 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis My New Kidney & Me by : Greg Baldauf

Download or read book My New Kidney & Me written by Greg Baldauf and published by . This book was released on 2020-03-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In December 2010, one phone message changed everything for Greg Baldauf. After thirty-five years of living with polycystic kidney disease (PKD), he learned that his kidneys were in renal failure and he would need a transplant to survive. My New Kidney & Me tells his story: the long search for a donor, the anxious lead-up to transplant surgery, the sometimes-disorienting recovery process, and the gratitude and joy that came after. Baldauf's words will be illuminating for anyone going through this situation, describing the physical, psychological, and emotional struggles that can come when facing a failure of the body. My New Kidney & Me brings the mysteries of transplant surgery out of the dark and hope into the light.

Silva's Diagnostic Renal Pathology

Author : Xin J. Zhou
Publisher : Cambridge University Press
ISBN 13 : 1316613984
Total Pages : 691 pages
Book Rating : 4.3/5 (166 download)

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Book Synopsis Silva's Diagnostic Renal Pathology by : Xin J. Zhou

Download or read book Silva's Diagnostic Renal Pathology written by Xin J. Zhou and published by Cambridge University Press. This book was released on 2017-03-02 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.