Physiologic And Chemical Basis For Metal Toxicity

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Physiologic and Chemical Basis for Metal Toxicity

Author : B. Venugopal
Publisher : Springer Science & Business Media
ISBN 13 : 1468429523
Total Pages : 245 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Physiologic and Chemical Basis for Metal Toxicity by : B. Venugopal

Download or read book Physiologic and Chemical Basis for Metal Toxicity written by B. Venugopal and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our purpose is to provide understanding for appropriate use of metals in a technical society. Knowledge of metal toxicity is needed for the preven tion, prediction, diagnosis, and therapy of adverse reactions from excess metals in mammals. Metal Toxicity in Mammals is presented in two volumes. Volume 1, Physiologic and Chemical Basis for Metal Toxic ity, provides the basis for understanding the toxic actions of metals recorded in Volume 2, Chemical Toxicity of Metals and Metalloids. The details and bases for many concepts summarized in Volume I are given, with appropriate references, in Volume 2. Thus, references for specific items in Volume 2 are not generally given in Volume 1. The authors reviewed the known toxicity of several heavy metals in anticipation of their use as multinutrient markers for NASA. As more and more metals were considered, the need for a complete review became obvious. This treatise supplants onerous searches of metal-toxicity litera ture up to 1975 and reviews the toxicity of all the metals of the periodic table on the basis of available relevant data. Books on pharmacological, nutritional, medical, veterinary, or industrial toxicity contain information about selected metals. More complete data about metals of public concern, such as mercury, lead, and cadmium, may be found in numerous books and reviews. The reader should refer to general texts and basic reference works, when specific references are not given, for general information.

Metal Toxicity in Mammals: Physiologic and chemical basis for metal toxicity

Author : Thomas D. Luckey
Publisher :
ISBN 13 :
Total Pages : 256 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Metal Toxicity in Mammals: Physiologic and chemical basis for metal toxicity by : Thomas D. Luckey

Download or read book Metal Toxicity in Mammals: Physiologic and chemical basis for metal toxicity written by Thomas D. Luckey and published by . This book was released on 1977 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:

AMetal Toxicity in Mammals 1

Author : Thomas D. Luckey
Publisher :
ISBN 13 :
Total Pages : 238 pages
Book Rating : 4.:/5 (64 download)

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Book Synopsis AMetal Toxicity in Mammals 1 by : Thomas D. Luckey

Download or read book AMetal Toxicity in Mammals 1 written by Thomas D. Luckey and published by . This book was released on 1977 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chelation Therapy in the Treatment of Metal Intoxication

Author : Jan Aaseth
Publisher : Academic Press
ISBN 13 : 0128030739
Total Pages : 388 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Chelation Therapy in the Treatment of Metal Intoxication by : Jan Aaseth

Download or read book Chelation Therapy in the Treatment of Metal Intoxication written by Jan Aaseth and published by Academic Press. This book was released on 2016-04-18 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chelation Therapy in the Treatment of Metal Intoxication presents a practical guide to the use of chelation therapy, from its basic chemistry, to available chelating antidotes, and the application of chelating agents. Several metals have long been known to be toxic to humans, and continue to pose great difficulty to treat. These challenges pose particular problems in industrial settings, with lead smelting known to be associated with hemopoietic alterations and paralyses, and the inhalation of mercury vapor in mercury mining being extremely detrimental to the central nervous system. Clinical experience has demonstrated that acute and chronic human intoxications with a range of metals can be treated efficiently by administration of chelating agents. Chelation Therapy in the Treatment of Metal Intoxication describes the chemical and biological principles of chelation in the treatment of these toxic metal compounds, including new chelators such as meso-2,3-dimercaptosuccinic acid (DMSA) and D,L-2,3-dimercapto-1-propanesulfonic acid (DMPS). Presents all the current findings on the potential for chelation as a therapy for metal intoxication Presents practical guidelines for selecting the most appropriate chelating agent Includes coverage on radionuclide exposure and metal storage diseases Describes the chemical and biological principles of chelation in the treatment of toxic metal compounds

Cellular Effects of Heavy Metals

Author : Gaspar Banfalvi
Publisher : Springer Science & Business Media
ISBN 13 : 9400704283
Total Pages : 348 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Cellular Effects of Heavy Metals by : Gaspar Banfalvi

Download or read book Cellular Effects of Heavy Metals written by Gaspar Banfalvi and published by Springer Science & Business Media. This book was released on 2011-03-02 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term “heavy metals” is used as a group name of toxic metals and metalloids (semimetals) causing contaminations and ecotoxicity. In strict chemical sense the density of heavy metals is higher than 5 g/cm3. From biological point of view as microelements they can be divided into two major groups. a. For their physiological function organisms and cells require essential microelements such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The other group of heavy metals is toxic to the health or environment. Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity of heavy metals is well known at organizational level, while less attention has been paid to their cellular effects. This book describes the toxicity of heavy metals on microorganisms, yeast, plant and animal cells. Other chapters of the book deal with their genotoxic, mutagenic and carcinogenic effects. The toxicity of several metals touch upon the aspects of environmental hazard, ecosystems and human health. Among the cellular responses of heavy metals irregularities in cellular mechanisms such as gene expression, protein folding, stress signaling pathways are among the most important ones. The final chapters deal with biosensors and removal of heavy metals. As everybody is eating, drinking and exposed to heavy metals on a daily basis, the spirit of the book will attract a wide audience.

Impact of Heavy Metals on the Environment

Author : Jean-Pierre Vernet
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 480 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Impact of Heavy Metals on the Environment by : Jean-Pierre Vernet

Download or read book Impact of Heavy Metals on the Environment written by Jean-Pierre Vernet and published by Elsevier Publishing Company. This book was released on 1992 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highlighted in this compilation of papers is the role and importance of heavy metals in the environment. It provides up-to-date information in a field of active research and progress, where the focus is on effects and interactions between the environment and organisms, as well as contaminant dynamics. Several papers address the impact of heavy metals on our health. The influence of metals on plants is described in an exhaustive study on lichens, which have been widely used as biomonitors for environmental contamination by heavy metals. Metals are also accumulated by animals, as seen in a chapter which focusses on sediment/benthic organism interactions and biomonitoring in fish. Soil interactions are discussed, as well as regional studies of freshwater sediments and the marine environment. The final part of the book addresses a crucial problem: the management of stabilized municipal waste sludges. As a result, the most important and significant recent trends are included, emphasizing interactions with and impacts of heavy metals on humans, animals, plants and soils.

Poisoning in the Modern World

Author : Ozgur Karcioglu
Publisher : BoD – Books on Demand
ISBN 13 : 1838807853
Total Pages : 130 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Poisoning in the Modern World by : Ozgur Karcioglu

Download or read book Poisoning in the Modern World written by Ozgur Karcioglu and published by BoD – Books on Demand. This book was released on 2019-06-19 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 400 years ago, Swiss alchemist and physician Paracelsus (1493-1541) cited: "All substances are poisons; there is none that is not a poison. The right dose differentiates a poison from a remedy." This is often condensed to: "The dose makes the poison." So, why are we overtly anxious about intoxications?In fact, poisons became a global problem with the industrial revolution. Pesticides, asbestos, occupational chemicals, air pollution, and heavy metal toxicity maintain high priority worldwide, especially in developing countries. Children between 0 and 5 years old are the most vulnerable to both acute and chronic poisonings, while older adults suffer from the chronic effects of chemicals. This book aims to raise awareness about the challenges of poisons, to help clinicians understand current issues in toxicology.

Metal Toxicity and Tolerance in Plants and Animals

Author : V. P. Singh
Publisher : Sarup & Sons
ISBN 13 : 9788176255875
Total Pages : 348 pages
Book Rating : 4.2/5 (558 download)

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Book Synopsis Metal Toxicity and Tolerance in Plants and Animals by : V. P. Singh

Download or read book Metal Toxicity and Tolerance in Plants and Animals written by V. P. Singh and published by Sarup & Sons. This book was released on 2005 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemical Toxicity of Metals and Metalloids

Author : B. Venugopal
Publisher : Springer
ISBN 13 : 9780306371776
Total Pages : 409 pages
Book Rating : 4.3/5 (717 download)

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Book Synopsis Chemical Toxicity of Metals and Metalloids by : B. Venugopal

Download or read book Chemical Toxicity of Metals and Metalloids written by B. Venugopal and published by Springer. This book was released on 1978-05-01 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Metal Toxicology

Author : Robert A. Goyer
Publisher : Elsevier
ISBN 13 : 1483288560
Total Pages : 525 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Metal Toxicology by : Robert A. Goyer

Download or read book Metal Toxicology written by Robert A. Goyer and published by Elsevier. This book was released on 2016-01-22 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal Toxicology addresses the effects of metals on human health, as well as their mechanisms of toxicity. Unlike most books on metal toxicity which are organized by individual metals, this book is arranged inan organ-by-organ basis. It deals with unifying mechanisms of metal toxicity within a given tissue, and with exposure of a tissue to more than one metal at a time. Unique aspect of organ-specific orientation Written by leading authorities in metal toxicology Chapters of special interest include Risk Assessment, Emerging Technologies, and Molecular Biological Techniques Serves as an excellent sourcebook of generalized information on metal toxicology, allowing for specific tissue-system referencing

Handbook on the Toxicology of Metals: Specific metals

Author : Lars Friberg
Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 758 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Handbook on the Toxicology of Metals: Specific metals by : Lars Friberg

Download or read book Handbook on the Toxicology of Metals: Specific metals written by Lars Friberg and published by Elsevier Science & Technology. This book was released on 1986 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapters on specific metals include physical and chemical properties, methods and problems of analysis, production and uses, environmental levels and exposures, metabolism, levels in tissues and biological fluids, effects and dose-response relationships, carcinogenicity, mutagenicity, teratogenicity and preventative measures, diagnosis, treatment and prognosis.

Metal Chelation in Medicine

Author : Robert R Crichton
Publisher : Royal Society of Chemistry
ISBN 13 : 1782623892
Total Pages : 322 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Metal Chelation in Medicine by : Robert R Crichton

Download or read book Metal Chelation in Medicine written by Robert R Crichton and published by Royal Society of Chemistry. This book was released on 2016-10-18 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.

Heavy Metal Toxicity in Public Health

Author : John Kanayochukwu Nduka
Publisher : BoD – Books on Demand
ISBN 13 : 1838804358
Total Pages : 162 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Heavy Metal Toxicity in Public Health by : John Kanayochukwu Nduka

Download or read book Heavy Metal Toxicity in Public Health written by John Kanayochukwu Nduka and published by BoD – Books on Demand. This book was released on 2020-06-24 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is often said that the “dosage” of any substance determines its remedy or poison effect. Heavy metal sources encompass sewage, pesticides, fertilizers, environmental contamination, occupational exposure/contact through inhalation, ingestion, and skin. Before the advent of technology/the industrial revolution, communicable diseases ravaged the human race but this seems to have given way to non-communicable diseases such as cancers, renal failure, hormonal distortion enzymes, inhibition of fetal growth, and DNA damage causing negative health issues due to heavy metals. This book brings to the fore probably the most recent experimental research/review on heavy metal contamination, remediating techniques, cellular tissue damage, and toxicological and antioxidant effects of heavy metals. It is hoped that its contents will make interesting reading for all.

Plant Metallomics and Functional Omics

Author : Gaurav Sablok
Publisher : Springer
ISBN 13 : 3030191036
Total Pages : 332 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Plant Metallomics and Functional Omics by : Gaurav Sablok

Download or read book Plant Metallomics and Functional Omics written by Gaurav Sablok and published by Springer. This book was released on 2019-07-04 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major portion of the planet earth is covered by seas and oceans representing 96.5% of the planet’s water, playing a detrimental role in sustaining the plant including crop diversity and productivity for human consumption. Water resources contain both soluble and transition metals, which are easily absorbed by plants through roots as a first point of contact and subsequently play important physiological and biological functions in plants. Transition metals such as copper (Cu), iron (Fe), manganese (Mn) and zinc (Zn) contribute to the plant productivity by playing key functional roles in the photosynthesis. In addition, to their major role in regulating the plant productivity, they also play an important role by acting as homeostatic regulators in uni-parentally inherited chloroplasts and maintains the flow of the electron transfer. It is worthwhile to mention that they play a critical role as transporters, which acts as electron balancing units for managing the electrostatic potential across the membranes. In contrast, some metals such as Cd, As play a significant role in inducing the stress mechanism and influencing either directly or in-directly Haber-Weiss reactions either through the production of the reactive oxygen species (ROS) or through the membrane damage thus leading to leakage of membrane transporters. However, besides playing a detrimental role as transporters in plant system, excessive accumulation of these metals due to the increasing contamination in the marginal soil and water are posing important threats to the plant system. Realizing the toxic effects of the metals, several physiological evidences have been laid for the credence of the metal toxicity and their concurrent effect on plant productivity. Increasing effects of the metals as toxicants can have three adverse effects on the populations: population can move, persist via local adaptation or phenotypic plasticity, or die. Next generation sequencing studies have revolutionized our abilities to detect the changes in expression profiles across an array of genes, which can in-turn help to develop early markers of metal induced stress. Plant Metallomics and Functional Omics: A System-Wide Perspective focuses on the applications of the system wide understanding of the biological and functional interplay occurring at the juncture of the metalloid induced stress and toxicity. The main goal of this book is to familiarize the readers with the most up-to-date information on metal-induced physiological changes in plant species.

Heavy Metals In Water

Author : Sanjay K. Sharma
Publisher : Royal Society of Chemistry
ISBN 13 : 1849738858
Total Pages : 382 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Heavy Metals In Water by : Sanjay K. Sharma

Download or read book Heavy Metals In Water written by Sanjay K. Sharma and published by Royal Society of Chemistry. This book was released on 2014-09-22 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the latest research on dissolved heavy metals in drinking water and their removal.

Trace Metals and Infectious Diseases

Author : Jerome O. Nriagu
Publisher : MIT Press
ISBN 13 : 0262552485
Total Pages : 501 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Trace Metals and Infectious Diseases by : Jerome O. Nriagu

Download or read book Trace Metals and Infectious Diseases written by Jerome O. Nriagu and published by MIT Press. This book was released on 2024-06-11 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experts explore the influence of trace metals on the pathogenesis of infectious diseases. Many parts of the world in which common infectious diseases are endemic also have the highest prevalence of trace metal deficiencies or rising rates of trace metal pollution. Infectious diseases can increase human susceptibility to adverse effects of metal exposure (at suboptimal or toxic levels), and metal excess or deficiency can increase the incidence or severity of infectious diseases. The co-clustering of major infectious diseases with trace metal deficiency or toxicity has created a complex web of interactions with serious but poorly understood health repercussions, yet has been largely overlooked in animal and human studies. This book focuses on the distribution, trafficking, fate, and effects of trace metals in biological systems. Its goal is to enhance our understanding of the relationships between homeostatic mechanisms of trace metals and the pathogenesis of infectious diseases. Drawing on expertise from a range of fields, the book offers a comprehensive review of current knowledge on vertebrate metal-withholding mechanisms and the strategies employed by different microbes to avoid starvation (or poisoning). Chapters summarize current, state-of-the-art techniques for investigating pathogen-metal interactions and highlight open question to guide future research. The book makes clear that improving knowledge in this area will be instrumental to the development of novel therapeutic measures against infectious diseases. Contributors M. Leigh Ackland, Vahid Fa Andisi, Angele L. Arrieta, Michael A. Bachman, J. Sabine Becker, Robert E. Black, Julia Bornhorst, Sascha Brunke, Joseph A. Caruso, Jennifer S. Cavet, Anson C. K. Chan, Christopher H. Contag, Heran Darwin, George V. Dedoussis, Rodney R. Dietert, Victor J. DiRita, Carol A. Fierke, Tamara Garcia-Barrera, David P. Giedroc, Peter-Leon Hagedoorn, James A. Imlay, Marek J. Kobylarz, Joseph Lemire, Wenwen Liu, Slade A. Loutet, Wolfgang Maret, Andreas Matusch, Trevor F. Moraes, Michael E. P. Murphy, Maribel Navarro, Jerome O. Nriagu, Ana-Maria Oros-Peusquens, Elisabeth G. Pacyna, Jozef M. Pacyna, Robert D. Perry, John M. Pettifor, Stephanie Pfaffen, Dieter Rehder, Lothar Rink, Anthony B. Schryvers, Ellen K. Silbergeld, Eric P. Skaar, Miguel C. P. Soares, Kyrre Sundseth, Dennis J. Thiele, Richard B. Thompson, Meghan M. Verstraete, Gonzalo Visbal, Fudi Wang, Mian Wang, Thomas J. Webster, Jeffrey N. Weiser, Günter Weiss, Inga Wessels, Bin Ye, Judith T. Zelikoff, Lihong Zhang

Cellular Effects of Heavy Metals

Author : Gaspar Banfalvi
Publisher : Springer
ISBN 13 : 9789400704299
Total Pages : 348 pages
Book Rating : 4.7/5 (42 download)

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Book Synopsis Cellular Effects of Heavy Metals by : Gaspar Banfalvi

Download or read book Cellular Effects of Heavy Metals written by Gaspar Banfalvi and published by Springer. This book was released on 2011-03-10 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term “heavy metals” is used as a group name of toxic metals and metalloids (semimetals) causing contaminations and ecotoxicity. In strict chemical sense the density of heavy metals is higher than 5 g/cm3. From biological point of view as microelements they can be divided into two major groups. a. For their physiological function organisms and cells require essential microelements such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The other group of heavy metals is toxic to the health or environment. Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity of heavy metals is well known at organizational level, while less attention has been paid to their cellular effects. This book describes the toxicity of heavy metals on microorganisms, yeast, plant and animal cells. Other chapters of the book deal with their genotoxic, mutagenic and carcinogenic effects. The toxicity of several metals touch upon the aspects of environmental hazard, ecosystems and human health. Among the cellular responses of heavy metals irregularities in cellular mechanisms such as gene expression, protein folding, stress signaling pathways are among the most important ones. The final chapters deal with biosensors and removal of heavy metals. As everybody is eating, drinking and exposed to heavy metals on a daily basis, the spirit of the book will attract a wide audience.