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Phthalates
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Book Synopsis Phthalates and Cumulative Risk Assessment by : National Research Council
Download or read book Phthalates and Cumulative Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2009-01-19 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.
Author :IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Publisher :IARC Monographs on the Evaluat ISBN 13 :9789283213246 Total Pages :0 pages Book Rating :4.2/5 (132 download)
Book Synopsis Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Download or read book Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC Monographs on the Evaluat. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309458625 Total Pages :423 pages Book Rating :4.3/5 (94 download)
Book Synopsis Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals by : National Academies of Sciences, Engineering, and Medicine
Download or read book Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-08-14 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects.
Download or read book Count Down written by Shanna H. Swan and published by Simon and Schuster. This book was released on 2022-02-08 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: An award-winning scientist, in this urgent, thought-provoking and meticulously researched book, shows how chemicals in the modern environment are changing--and endangering--human sexuality and fertility on the grandest scale.
Book Synopsis Phthalate Esters by : Charles Staples
Download or read book Phthalate Esters written by Charles Staples and published by Springer. This book was released on 2003-07-31 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phthalate esters are an important class of chemicals widely used in commercial applications, primarily as plasticizers to soften vinyl, but they are also used in consumer products. This book reviews the state of the scientific knowledge of phthalate esters in the environment. Key information reported includes: analytical methodologies; a compilation of concentration measurements in water, sediment, soil, air, dust, and food; plus an assessment of critical exposure pathways. In addition, key physical properties data and fate characteristics that control exposure are reviewed. Also included are pertinent ecotoxicity data and mammalian toxicity and human health information. Finally, the monograph addresses potential environmental risks.
Book Synopsis Bisphenol A and Phthalates by : Bradley C. Vaughn
Download or read book Bisphenol A and Phthalates written by Bradley C. Vaughn and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bisphenol A is a difunctional building block of several important plastics and plastic additives. Suspected of being hazardous to humans since the 1930s, concerns about the use of bisphenol A in consumer products were regularly reported in the news media in 2008 after several governments issued reports questioning its safety, causing some retailers to remove products made of it from their shelves. Additionally, phthalates, are esters of phthalic acid and are mainly used as plasticisers (substances added to plastics to increase their flexibility, transparency, durability, and longevity). They are primarily used to soften polyvinyl chloride. This book examines both bisphenol A and phthalates discussing and presenting numerous topical and related data on these compounds and their uses, health effects and environmental risks.
Download or read book Phthalates written by Gerardo L. Moretti and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phthalates are esters of phthalic acid and are a group of chemicals of high environmental relevance due to their production rates and ecotoxicological potential. Phthalates are mainly used as plasticizers in PVC plastics, wherein many consumer products contain specific members of this family of chemicals. In this book, the authors present current research on the chemical properties and impacts on health and the environment of phthalates. Topics include phthalate contamination in two estuaries from the Basque Coast; bioaccumulation and intracellular signal modifications of in vivo and in vitro models of phthalate esters; DEHP behavior in contact with liquid food simulants, blood, saliva and soil; removal of phthalates from the environment; gas phase fragmentation reactions of phthalate ions; the effects of DEHP exposure on brain development; and phthalate toxicogenomics and health effects.
Book Synopsis Phthalate Esters by : Charles Staples
Download or read book Phthalate Esters written by Charles Staples and published by Springer Science & Business Media. This book was released on 2003-08-25 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phthalate esters are an important class of chemicals widely used in commercial applications, primarily as plasticizers to soften vinyl, but they are also used in consumer products. This book reviews the state of the scientific knowledge of phthalate esters in the environment. Key information reported includes: analytical methodologies; a compilation of concentration measurements in water, sediment, soil, air, dust, and food; plus an assessment of critical exposure pathways. In addition, key physical properties data and fate characteristics that control exposure are reviewed. Also included are pertinent ecotoxicity data and mammalian toxicity and human health information. Finally, the monograph addresses potential environmental risks.
Book Synopsis Phthalates and Cumulative Risk Assessment by : National Research Council
Download or read book Phthalates and Cumulative Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2008-12-19 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.
Book Synopsis Endocrine Disruption and Human Health by : Philippa D. Darbre
Download or read book Endocrine Disruption and Human Health written by Philippa D. Darbre and published by Academic Press. This book was released on 2015-03-21 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations
Download or read book Phthalates written by Miguel Owens and published by . This book was released on 2015 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phthalates are ester derivatives that have been used to alter the flexibility of plastics since the 1930s, and are ubiquitous in our daily life. The first chapter of this book discusses how perinatal exposure to phthalates may induce alterations in brain neural growth and differentiation, with neurocognitive and behavioral consequences. Chapter two investigates the advantages and/or disadvantages of some analytical methods used in the past few years for chromatographic detection. The fourth chapter discusses the widespread application of phthalates and the role of liquid chromatography-mass spectrometry technique used in the detection, determination and confirmation of the chemical. The final chapter examines the assessment of phthalate exposure in polymer materials with advanced numerical algorithms.
Author :IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Publisher :World Health Organization ISBN 13 :9283212770 Total Pages :574 pages Book Rating :4.2/5 (832 download)
Book Synopsis Some Industrial Chemicals by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Download or read book Some Industrial Chemicals written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 2000 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication represents the views and expert opinion of an IARC Working Group which met in Lyon, 15-22 February 2000.
Book Synopsis Handbook of Research on Environmental and Human Health Impacts of Plastic Pollution by : Khursheed Ahmad Wani
Download or read book Handbook of Research on Environmental and Human Health Impacts of Plastic Pollution written by Khursheed Ahmad Wani and published by IGI Global, Engineering Science Reference. This book was released on 2019-07-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book examines the negative impacts of plastic and explores different biotechnological interventions to plastic pollution. It also generates an awareness of the use of plastics and its impact on the environment, human health, and other ecosystems"--
Book Synopsis Handbook of Food Analysis - Two Volume Set by : Leo M.L. Nollet
Download or read book Handbook of Food Analysis - Two Volume Set written by Leo M.L. Nollet and published by CRC Press. This book was released on 2015-06-10 with total page 1530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated to reflect changes in the industry during the last ten years, The Handbook of Food Analysis, Third Edition covers the new analysis systems, optimization of existing techniques, and automation and miniaturization methods. Under the editorial guidance of food science pioneer Leo M.L. Nollet and new editor Fidel Toldra, the chapters take an in
Book Synopsis Phthalates and Bisphenol-A in Plastics and Possible Human Health Effects by : Gail N. Moye
Download or read book Phthalates and Bisphenol-A in Plastics and Possible Human Health Effects written by Gail N. Moye and published by Nova Biomedical Books. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the safety of phthalates and bisphenol-A in everyday consumer products. The American Chemistry Council represents the leading business of chemistry. Products supplied by the chemistry sector are essential in manufacturing, agriculture, energy, transportation, technology, communications, health, education, defence, and virtually every aspect of our lives. Basic industrial chemicals are the raw materials for thousands of other products including plastics, water treatment chemicals, detergents, pharmaceuticals and agricultural chemicals. Recent media attention has created public concern and confusion about some of these chemicals - a family of compounds called phthalate esters, and another compound bisphenol-A. Bisphenol-A (BPA) is a synthetic sex hormone that's been linked to serious diseases at low doses of exposure. Studies conducted on laboratory animals and cell cultures have linked low doses of BPA to obesity, diabetes, thyroid disease, breast cancer, prostate cancer and other illnesses. BPA exposure is widespread and has been found in 95% of Americans tested including in breast milk. New research related to this field is presented in this book.
Book Synopsis Toxicants in Food Packaging and Household Plastics by : Suzanne M. Snedeker
Download or read book Toxicants in Food Packaging and Household Plastics written by Suzanne M. Snedeker and published by Springer. This book was released on 2014-08-13 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a comprehensive resource on toxicants that can be released from food packaging materials and household plastics. Chapters include sources and levels of chemical exposure, known and suspected health effects and the identification of data gaps with recommendations for further research. In addition, regulatory approaches and risk assessment challenges in the United States and Europe are discussed. Chapters cover both the more widely known chemicals that can migrate from food packaging (bisphenol A, perfluorinated chemicals), and household plastics (lead, phthalates, brominated flame retardants), as well as chemicals that are just entering use in food packaging (nanomaterials in polymer food packaging) and chemicals recently identified as migrating from food packaging to food stuffs (phthalates, benzophenones, antimony, methylnaphthalene and the alkylphenols nonylphenol and octylphenol). Chapters on phthalates and brominated flame retardants discuss challenges that arise with the use of replacement chemicals. The health effect sections of chapters have drawn on a wide variety of toxicological endpoints and recommend approaches to better assess toxicological risks in vulnerable human populations. Reflecting the global nature of our food supply and household consumer goods, contributions have been drawn from international experts. A wide range of scientists will find this book to be useful, including toxicologists, environmental health scientists, food scientists, and regulators.
Book Synopsis Toxicological Profile for Diethyl Phthalate by :
Download or read book Toxicological Profile for Diethyl Phthalate written by and published by . This book was released on 1995 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
