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Phase 2 Safety Analysis Report
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Book Synopsis Phase II Safety Analysis Report by : National Synchrotron Light Source (Organization : U.S.)
Download or read book Phase II Safety Analysis Report written by National Synchrotron Light Source (Organization : U.S.) and published by . This book was released on 1989 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis High-level Waste Preclosure Systems Safety Analysis by : D. M. Ligon
Download or read book High-level Waste Preclosure Systems Safety Analysis written by D. M. Ligon and published by . This book was released on 1987 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Format and Content of the Safety Analysis Report for Nuclear Power Plants by : International Atomic Energy Agency
Download or read book Format and Content of the Safety Analysis Report for Nuclear Power Plants written by International Atomic Energy Agency and published by IAEA. This book was released on 2004 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Safety Guide is intended primarily for use with land based stationary thermal nuclear power plants but it may, in parts, have a wider applicability to other nuclear facilities. It provides recommendations and guidance on the possible format and content of a SAR in support of a request to the State regulatory body for authorization to construct and or operate a nuclear power plant. As such, it contains recommendations on meeting the requirements of Safety guide GS-R-1 "Legal and governmental infrastructure for nuclear, radioactive waste and transport safety" (2000, ISBN 9201008007)
Book Synopsis Final Safety Analysis Report for the Ground Test Accelerator (GTA), Phase 2 by :
Download or read book Final Safety Analysis Report for the Ground Test Accelerator (GTA), Phase 2 written by and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development and Application of Level 2 Probabilistic Safety Assessment for Nuclear Power Plants by : International Atomic Energy Agency
Download or read book Development and Application of Level 2 Probabilistic Safety Assessment for Nuclear Power Plants written by International Atomic Energy Agency and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this Safety Guide is to provide recommendations for meeting the IAEA safety requirements in performing or managing a level 2 probabilistic safety assessment (PSA) project for a nuclear power plant; thus it complements the Safety Guide on level 1 PSA. One of the aims of this Safety Guide is to promote a standard framework, standard terms and a standard set of documents for level 2 PSAs to facilitate regulatory and external peer review of their results. It describes all elements of the level 2 PSA that need to be carried out if the starting point is a fully comprehensive level 1 PSA. Contents: 1. Introduction; 2. PSA project management and organization; 3. Identification of design aspects important to severe accidents and acquisition of information; 4. Interface with level 1 PSA: Grouping of sequences; 5. Accident progression and containment analysis; 6. Source terms for severe accidents; 7. Documentation of the analysis: Presentation and interpretation of results; 8. Use and applications of the PSA; References; Annex I: Example of a typical schedule for a level 2 PSA; Annex II: Computer codes for simulation of severe accidents; Annex III: Sample outline of documentation for a level 2 PSA study.
Book Synopsis Supplement No. 1 to the Safety Evaluation Report by the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, in the Matter of Ohio Edison Company, Toledo Edison Company, Cleveland Electric Illuminating Company, Duquesne Light Company, and Pennsylvania Power Comapany, Erie Nuclear Plant, Units 1 and 2, Docket Nos. STN 50-580 and STN 50-581 by : U.S. Nuclear Regulatory Commission. Office of Nuclear Reactor Regulation
Download or read book Supplement No. 1 to the Safety Evaluation Report by the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, in the Matter of Ohio Edison Company, Toledo Edison Company, Cleveland Electric Illuminating Company, Duquesne Light Company, and Pennsylvania Power Comapany, Erie Nuclear Plant, Units 1 and 2, Docket Nos. STN 50-580 and STN 50-581 written by U.S. Nuclear Regulatory Commission. Office of Nuclear Reactor Regulation and published by . This book was released on 1979 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Supplement No. 2 to the Safety Evaluation Report by the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission in the Matter of Public Service Company of Oklahoma, Et Al., Black Fox Station, Units 1 and 2, Docket Nos. STN 50-556 and STN 50-557 by : U.S. Nuclear Regulatory Commission. Office of Nuclear Reactor Regulation
Download or read book Supplement No. 2 to the Safety Evaluation Report by the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission in the Matter of Public Service Company of Oklahoma, Et Al., Black Fox Station, Units 1 and 2, Docket Nos. STN 50-556 and STN 50-557 written by U.S. Nuclear Regulatory Commission. Office of Nuclear Reactor Regulation and published by . This book was released on 1979 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Phase 2 Safety Analysis Report: National Synchrotron Light Source by : P. (ed.). Stefan
Download or read book Phase 2 Safety Analysis Report: National Synchrotron Light Source written by P. (ed.). Stefan and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Prevention and Treatment of Missing Data in Clinical Trials by : National Research Council
Download or read book The Prevention and Treatment of Missing Data in Clinical Trials written by National Research Council and published by National Academies Press. This book was released on 2010-12-21 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.
Book Synopsis Drug Safety Data by : Michael J. Klepper
Download or read book Drug Safety Data written by Michael J. Klepper and published by Jones & Bartlett Publishers. This book was released on 2010-09-15 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk was selected for The First Clinical Research Bookshelf - Essential reading for clinical research professionals by the Journal of Clinical Research Best Practices. Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk provides drug safety/pharmacovogilance professionals, pharmaceutical and clinical research scientists, statisticians, programmers, medical writers, and technicians with an accessible, practical framework for the analysis, summary and interpretation of drug safety data. The only guide of its kind, Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk is an invaluable reference for pre- and post-marketing risk assessment. With decades of pharmaceutical research and drug safety expertise, authors Dr. Klepper and Dr. Cobert discuss how quality planning, safety training, and data standardization result in significant cost, time, and resource savings. Through illustrative, step-by-step instruction, Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk is the definitive guide to drug safety data analysis and reporting. Key features include: * Step-by-step instruction on how to analyze, summarize and interpret safety data for mandatory governmental safety reports * Pragmatic tips...and mistakes to avoid * Simple explanations of what safety data are collected, and what the data mean * Practical approaches to determining a drug effect and understanding its clinical significance * Guidance for determining risk throughout the lifecycle of a drug, biologic or nutraceutical * Examples of user-friendly data displays that enhance safety signal identification * Ways to improve data quality and reduce the time, resources and costs involved in mandatory safety reporting * Relevant material for the required training of drug safety/pharmacovigilance professionals * SPECIAL FEATURE: Actual examples of an Integrated Analysis of Safety (IAS) -used in the preparation of the Integrated Summary of Safety (ISS) and the Summary of Clinical Safety (SCS) reports -, and the Periodic Safety Update Report (PSUR)
Book Synopsis Safety Evaluation Report, Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, in the Matter of by : U.S. Nuclear Regulatory Commission. Office of Nuclear Reactor Regulation
Download or read book Safety Evaluation Report, Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, in the Matter of written by U.S. Nuclear Regulatory Commission. Office of Nuclear Reactor Regulation and published by . This book was released on 1977 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Phase 2 Safety Analysis Report written by and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Phase II program was established in order to provide additional space for experiments, and also staging and equipment storage areas. It also provides additional office space and new types of advanced instrumentation for users. This document will deal with the new safety issues resulting from this extensive expansion program, and should be used as a supplement to BNL Report No. 51584 ''National Synchrotron Light Source Safety Analysis Report, '' July 1982 (hereafter referred to as the Phase I SAR). The initial NSLS facility is described in the Phase I SAR. It comprises two electron storage rings, an injection system common to both, experimental beam lines and equipment, and office and support areas, all of which are housed in a 74,000 sq. ft. building. The X-ray Ring provides for 28 primary beam ports and the VUV Ring, 16. Each port is capable of division into 2 or 3 separate beam lines. All ports receive their synchrotron light from conventional bending magnet sources, the magnets being part of the storage ring lattice. 4 refs.
Book Synopsis Supplement No. 1 to the Safety Evaluation Report, Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, in the Matter of by : U.S. Nuclear Regulatory Commission. Office of Nuclear Reactor Regulation
Download or read book Supplement No. 1 to the Safety Evaluation Report, Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, in the Matter of written by U.S. Nuclear Regulatory Commission. Office of Nuclear Reactor Regulation and published by . This book was released on 1978 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Agency for Healthcare Research and Quality/AHRQ Publisher :Government Printing Office ISBN 13 :1587634333 Total Pages :385 pages Book Rating :4.5/5 (876 download)
Book Synopsis Registries for Evaluating Patient Outcomes by : Agency for Healthcare Research and Quality/AHRQ
Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.
Book Synopsis Safety Study Application Guide. Safety Analysis Report Update Program by :
Download or read book Safety Study Application Guide. Safety Analysis Report Update Program written by and published by . This book was released on 1993 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: Martin Marietta Energy Systems, Inc., (Energy Systems) is committed to performing and documenting safety analyses for facilities it manages for the Department of Energy (DOE). Included are analyses of existing facilities done under the aegis of the Safety Analysis Report Upgrade Program, and analyses of new and modified facilities. A graded approach is used wherein the level of analysis and documentation for each facility is commensurate with the magnitude of the hazard(s), the complexity of the facility and the stage of the facility life cycle. Safety analysis reports (SARs) for hazard Category 1 and 2 facilities are usually detailed and extensive because these categories are associated with public health and safety risk. SARs for Category 3 are normally much less extensive because the risk to public health and safety is slight. At Energy Systems, safety studies are the name given to SARs for Category 3 (formerly {open_quotes}low{close_quotes}) facilities. Safety studies are the appropriate instrument when on-site risks are limited to irreversible consequences to a few people, and off-site consequences are limited to reversible consequences to a few people. This application guide provides detailed instructions for performing safety studies that meet the requirements of DOE Orders 5480.22, {open_quotes}Technical Safety Requirements, {close_quotes} and 5480.23, {open_quotes}Nuclear Safety Analysis Reports.{close_quotes} A seven-chapter format has been adopted for safety studies. This format allows for discussion of all the items required by DOE Order 5480.23 and for the discussions to be readily traceable to the listing in the order. The chapter titles are: (1) Introduction and Summary, (2) Site, (3) Facility Description, (4) Safety Basis, (5) Hazardous Material Management, (6) Management, Organization, and Institutional Safety Provisions, and (7) Accident Analysis.
Author :National Research Council (U.S.). Committee on Lessons Learned from the Fukushima Nuclear Accident for Improving Safety and Security of U.S. Nuclear Plants Publisher :National Academy Press ISBN 13 :9780309272537 Total Pages :394 pages Book Rating :4.2/5 (725 download)
Book Synopsis Lessons Learned from the Fukushima Nuclear Accident for Improving Safety of U.S. Nuclear Plants by : National Research Council (U.S.). Committee on Lessons Learned from the Fukushima Nuclear Accident for Improving Safety and Security of U.S. Nuclear Plants
Download or read book Lessons Learned from the Fukushima Nuclear Accident for Improving Safety of U.S. Nuclear Plants written by National Research Council (U.S.). Committee on Lessons Learned from the Fukushima Nuclear Accident for Improving Safety and Security of U.S. Nuclear Plants and published by National Academy Press. This book was released on 2014-10-29 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: The March 11, 2011, Great East Japan Earthquake and tsunami sparked a humanitarian disaster in northeastern Japan. They were responsible for more than 15,900 deaths and 2,600 missing persons as well as physical infrastructure damages exceeding $200 billion. The earthquake and tsunami also initiated a severe nuclear accident at the Fukushima Daiichi Nuclear Power Station. Three of the six reactors at the plant sustained severe core damage and released hydrogen and radioactive materials. Explosion of the released hydrogen damaged three reactor buildings and impeded onsite emergency response efforts. The accident prompted widespread evacuations of local populations, large economic losses, and the eventual shutdown of all nuclear power plants in Japan. "Lessons Learned from the Fukushima Nuclear Accident for Improving Safety and Security of U.S. Nuclear Plants" is a study of the Fukushima Daiichi accident. This report examines the causes of the crisis, the performance of safety systems at the plant, and the responses of its operators following the earthquake and tsunami. The report then considers the lessons that can be learned and their implications for U.S. safety and storage of spent nuclear fuel and high-level waste, commercial nuclear reactor safety and security regulations, and design improvements. "Lessons Learned" makes recommendations to improve plant systems, resources, and operator training to enable effective ad hoc responses to severe accidents. This report's recommendations to incorporate modern risk concepts into safety regulations and improve the nuclear safety culture will help the industry prepare for events that could challenge the design of plant structures and lead to a loss of critical safety functions. In providing a broad-scope, high-level examination of the accident, "Lessons Learned" is meant to complement earlier evaluations by industry and regulators. This in-depth review will be an essential resource for the nuclear power industry, policy makers, and anyone interested in the state of U.S. preparedness and response in the face of crisis situations.
Author :Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation Publisher :National Academies Press ISBN 13 :0309133343 Total Pages :422 pages Book Rating :4.3/5 (91 download)
Book Synopsis Health Risks from Exposure to Low Levels of Ionizing Radiation by : Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Download or read book Health Risks from Exposure to Low Levels of Ionizing Radiation written by Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation and published by National Academies Press. This book was released on 2006-03-23 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.
