Pharmacotherapy Of Pulmonary Hypertension

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Pharmacotherapy of Pulmonary Hypertension

Author : Marc Humbert
Publisher : Springer Science & Business Media
ISBN 13 : 3642386644
Total Pages : 569 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Pharmacotherapy of Pulmonary Hypertension by : Marc Humbert

Download or read book Pharmacotherapy of Pulmonary Hypertension written by Marc Humbert and published by Springer Science & Business Media. This book was released on 2013-10-04 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification, pathophysiology, pathology, biomarkers and animal models of the disease, thus laying the conceptual basis for what follows. The middle section provides an overview of the established therapies, such as calcium channel blockers, prostanoids, endothelin receptor antagonists, phosphodiesterase-5 inhibitors and inhaled nitric oxide. The last section explores novel pathways and emerging therapeutic approaches including soluble guanylate cyclase stimulators, Rho-kinase inhibitors, inhibitors of serotonin receptors and transporters, peptide growth factors, vasoactive peptides, modulators of redox equilibrium and cyclic nucleotide homeostasis, as well as immunosuppressive and anti-proliferative agents. Particular attention is given to the clinical applications of these experimental therapies, that are on the horizon. The book thus spans the continuum from basic science to clinical applications.

Introduction to Basics of Pharmacology and Toxicology

Author : Abialbon Paul
Publisher : Springer Nature
ISBN 13 : 9813360097
Total Pages : 1156 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Introduction to Basics of Pharmacology and Toxicology by : Abialbon Paul

Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Diagnosis and Treatment of Pulmonary Hypertension

Author : Yoshihiro Fukumoto
Publisher : Springer
ISBN 13 : 9812878408
Total Pages : 236 pages
Book Rating : 4.8/5 (128 download)

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Book Synopsis Diagnosis and Treatment of Pulmonary Hypertension by : Yoshihiro Fukumoto

Download or read book Diagnosis and Treatment of Pulmonary Hypertension written by Yoshihiro Fukumoto and published by Springer. This book was released on 2017-01-05 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on pulmonary arterial hypertension (PAH, Group 1) and chronic thromboembolic pulmonary hypertension (CTEPH, Group 4) among the various groups of pulmonary hypertension (PH) whose classification was updated into five major categories at the 5th World Symposium held in Nice, France, in 2013. Readers will find recent progress, methods, and up-to-date information on PH mechanisms, diagnostic images, and treatment in the management of PH.This volume, with contributions by leading researchers worldwide in the field , consists of five parts, starting with the fundamentals of PH, then pathophysiology and genetics, treatment, and right ventricular function.

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension

Author : Toshio Nakanishi
Publisher : Springer Nature
ISBN 13 : 9811511853
Total Pages : 374 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension by : Toshio Nakanishi

Download or read book Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension written by Toshio Nakanishi and published by Springer Nature. This book was released on 2020-02-28 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.

Treatment of Pulmonary Hypertension

Author : Brendan Madden
Publisher : Springer
ISBN 13 : 9783319135809
Total Pages : 0 pages
Book Rating : 4.1/5 (358 download)

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Book Synopsis Treatment of Pulmonary Hypertension by : Brendan Madden

Download or read book Treatment of Pulmonary Hypertension written by Brendan Madden and published by Springer. This book was released on 2015-09-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title will be presented as highly practical information on pharmaceutical options in pulmonary hypertension, written in a quick-access, no-nonsense format. The emphasis will be on a just-the-facts clinical approach, heavy on tabular material, light on dense prose. The involvement of the ISCP will ensure that the best quality contributors will be involved and establish a consistent approach to each topic in the series. Each volume is designed to be between 100 and 150 pages containing practical illustrations and designed to improve understand and practical usage of cardiovascular drugs in specific clinical areas.

Treatment of Pulmonary Hypertension

Author : Brendan Madden
Publisher : Springer
ISBN 13 : 3319135813
Total Pages : 182 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Treatment of Pulmonary Hypertension by : Brendan Madden

Download or read book Treatment of Pulmonary Hypertension written by Brendan Madden and published by Springer. This book was released on 2015-08-10 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title will be presented as highly practical information on pharmaceutical options in pulmonary hypertension, written in a quick-access, no-nonsense format. The emphasis will be on a just-the-facts clinical approach, heavy on tabular material, light on dense prose. The involvement of the ISCP will ensure that the best quality contributors will be involved and establish a consistent approach to each topic in the series. Each volume is designed to be between 100 and 150 pages containing practical illustrations and designed to improve understand and practical usage of cardiovascular drugs in specific clinical areas.

Pharmacotherapy of Pulmonary Hypertension

Author : Marc Humbert
Publisher :
ISBN 13 : 9783642386657
Total Pages : 588 pages
Book Rating : 4.3/5 (866 download)

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Book Synopsis Pharmacotherapy of Pulmonary Hypertension by : Marc Humbert

Download or read book Pharmacotherapy of Pulmonary Hypertension written by Marc Humbert and published by . This book was released on 2013-10-31 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diagnosis and Management of Pulmonary Hypertension

Author : James R. Klinger
Publisher : Humana Press
ISBN 13 : 1493926365
Total Pages : 474 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Diagnosis and Management of Pulmonary Hypertension by : James R. Klinger

Download or read book Diagnosis and Management of Pulmonary Hypertension written by James R. Klinger and published by Humana Press. This book was released on 2015-05-25 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of pulmonary hypertensive diseases, the current understanding of their pathobiology, and a contemporary approach to diagnosis and treatment. It discusses the definition and classification of these disorders and the epidemiology of pulmonary arterial hypertension (PAH); explores the approach to diagnosis and evaluation via methods such as echocardiography, right heart catheterization, and cardiopulmonary exercise testing; describes the major drug classes used to treat PAH and the cell signaling pathways that they target as well as adjunct and investigative therapies; and highlights special situations that are particularly challenging in the management of PAH. Written by experts in their respective fields, Diagnosis and Management of Pulmonary Hypertension is a valuable resource for pulmonologists, cardiologists, and practitioners in internal medicine and critical care.

Pulmonary Arterial Hypertension

Author : Robyn Barst
Publisher : John Wiley & Sons
ISBN 13 : 0470997389
Total Pages : 270 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Pulmonary Arterial Hypertension by : Robyn Barst

Download or read book Pulmonary Arterial Hypertension written by Robyn Barst and published by John Wiley & Sons. This book was released on 2008-09-15 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: First book dedicated to this disease, previously thought to be incurable, but with the advent of new drugs, now amenable to management and a much improved prognosis for patients From the PAH Association, the leading experts in field Incorporates the latest AACP management guidelines Includes evidence-based treatment algorithms based on the recently updated ACCP Guidelines for Medical Treatment Aimed at specialists in pulmonology and cardiovascular disease, this volume provides the clinician with the most up to date information on the effective management of PAH

Pulmonary hypertension

Author : Sics Editore
Publisher : SICS Editore
ISBN 13 : 8869300552
Total Pages : 45 pages
Book Rating : 4.8/5 (693 download)

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Book Synopsis Pulmonary hypertension by : Sics Editore

Download or read book Pulmonary hypertension written by Sics Editore and published by SICS Editore. This book was released on 2014-10-01 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulmonary hypertension (PH) denotes a state where the mean pulmonary artery pressure is 25 mmHg or higher (measured invasively via right heart catheterisation in specialist medical care). In clinical practice, echocardiography is used as a screening tool because it provides the means to indirectly estimate the pressure within the pulmonary arteries. The most common causes of increased pulmonary blood pressure are problems related to the left side of the heart (such as ventricular failure and valvular defects) and hypoxaemia caused either by lung disease or other conditions (such as COPD, pulmonary fibrosis and sleep apnoea). In these situations the increase in pulmonary blood pressure is a secondary haemodynamic phenomenon and, according to current understanding, it only plays a minor role as far as the management of the condition is concerned. At present, no evidence exists on the benefit of PH medication in the treatment of these conditions. Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are markedly rarer causes of PH, and in these conditions both pulmonary blood pressure and pulmonary vascular resistance play a major role. The principal mechanism behind PAH is an endothelial dysfunction in the small pulmonary arteries leading to an imbalance between vasoactive mediators (e.g. prostacycline, nitrous oxide and endothelin), which are responsible for the dilatation and constriction of the vessels as well as for enhancing or inhibiting vascular proliferation. Promising new drugs have been introduced during the last few years for the treatment of PAH, which improve the patient’s functional capacity and probably also the prognosis. The investigations of PH are always carried out in specialist medical care, and the diagnosis and treatment of PAH and CTEPH should be concentrated in specialist centres.

Pulmonary Arterial Hypertension

Author : Jochen Antel
Publisher : IOS Press
ISBN 13 : 1607506017
Total Pages : 116 pages
Book Rating : 4.6/5 (75 download)

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Book Synopsis Pulmonary Arterial Hypertension by : Jochen Antel

Download or read book Pulmonary Arterial Hypertension written by Jochen Antel and published by IOS Press. This book was released on 2010 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulmonary hypertension is a fatal lung and heart disease. It is characterized by shortness of breath, fatigue and fainting. It is exacerbated by an increase of the pressure in the lung vasculature through exercise, leading to progressive worsening of hemodynamics, right ventricular hypertrophy, right heart insufficiency and finally right heart failure. This book focuses on pulmonary arterial hypertension, a rare and progressive subgroup of pulmonary hypertension, which is today incurable and terminally faal. Classification of pulmonary arterial hypertension, its pathology, and strategies for future therapy will be of interest both to those suffering from the disease and those who take care of patients. This volume will also engage physicians and other scientists contributing to an understanding of the pathophysiology of pulmonary arterial hypertension and attempting to extend life of humans with pulmonary arterial hypertension by developing causal and curative therapies.

Pulmonary Hypertension

Author : Norbert F. Voelkel
Publisher : PMPH-USA
ISBN 13 : 9781607950370
Total Pages : 380 pages
Book Rating : 4.9/5 (53 download)

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Book Synopsis Pulmonary Hypertension by : Norbert F. Voelkel

Download or read book Pulmonary Hypertension written by Norbert F. Voelkel and published by PMPH-USA. This book was released on 2011 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulmonary hypertension is a world�wide problem which is gaining greater attention and is more frequently diagnosed now, more than the past ten or twenty years, because of the use and interpretation of echocardiograms. Pulmonary Hypertension raises questions and discusses concepts which will address the issue of etiology of pulmonary hypertension, its pathobiology with its close proximity to cancer, and the consequences of severe PH which is right heart failure and death.

The Right Heart

Author : Sean P. Gaine
Publisher : Springer
ISBN 13 : 1447123980
Total Pages : 326 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis The Right Heart by : Sean P. Gaine

Download or read book The Right Heart written by Sean P. Gaine and published by Springer. This book was released on 2014-05-12 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: The heart and lung are intricately linked. When the heart is affected by disease, the lungs will often show some related pathological or clinical conditions and vice versa. Pulmonary heart disease is by definition a condition when the lungs cause the heart to fail. The left ventricle in combination with the other structures in the “left heart” pumps blood throughout the body. The right ventricle (and structures of the “right heart”) pumps blood to the lungs where it is oxygenated and returned to the left heart for distribution. In normal circumstances, the right heart pumps blood into the lungs without any resistance. The lungs usually have minimal pressure and the right heart easily pumps blood through. However when there is lung disease present, like emphysema, chronic obstructive lung disease (COPD) or pulmonary hypertension- the small blood vessels become very stiff and rigid. The right ventricle is no longer able to push blood into the lungs and eventually fails. This is known as pulmonary heart disease. Pulmonary heart disease is also known as right heart failure or cor pulmonale. The chief cause of right heart failure is the increase in blood pressure in the lungs (pulmonary artery).

Pulmonary Arterial Hypertension and Interstitial Lung Diseases

Author : Robert P. Baughman
Publisher : Springer Science & Business Media
ISBN 13 : 1603270744
Total Pages : 255 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Pulmonary Arterial Hypertension and Interstitial Lung Diseases by : Robert P. Baughman

Download or read book Pulmonary Arterial Hypertension and Interstitial Lung Diseases written by Robert P. Baughman and published by Springer Science & Business Media. This book was released on 2009-01-01 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interstitial lung disease (ILD) is a broad category of lung diseases that includes more than 150 disorders characterized by scarring or fibrosis of the lungs. In Pulmonary Arterial Hypertension and Interstitial Lung Disease: A Clinical Guide, renowned experts provide a state-of-the-art overview of the problems seen by physicians in the clinical management of ILDs. Divided into two sections, the first part provides and update on general issues and introduces both interstitial lung disease and associated pulmonary hypertension. A detailed analysis of the pathology of the various interstitial lung diseases is also provided. The second part addresses specific categories of disease. Bronchiolitis, hypersensitivity pneumonitis, and other conditions are covered, and the use of inspiratory and expiratory high resolution CT scan is discussed as well. This important new text is an invaluable resource for the practicing physician who must be aware of the broad and troubling manifestations of interstitial lung disease.

Handbook of Inpatient Cardiology

Author : Bryan J. Wells
Publisher : Springer Nature
ISBN 13 : 3030478688
Total Pages : 545 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Handbook of Inpatient Cardiology by : Bryan J. Wells

Download or read book Handbook of Inpatient Cardiology written by Bryan J. Wells and published by Springer Nature. This book was released on 2020-07-22 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a pocket-sized resource to aid with the diagnosis and management of cardiovascular disease in the inpatient setting. Containing up-to-date information from guidelines and clinical trials, this book is the only handbook-style reference on cardiac care designed specifically for the hospitalist. The first section of the book covers cardiac pathology with an emphasis on evidence-based and guideline-based approaches to patient care. Each chapter focuses on a specific cardiovascular disease state such as acute coronary syndrome, atrial fibrillation, pulmonary hypertension, and aortic disease. The second section examines the differential diagnoses and recommended workup for common cardiac chief complaints including chest pain, palpitations, syncope, and dyspnea. The third and final section discusses indications and interpretation of commonly used cardiac procedures and imaging modalities. This book provides a concise review over a broad range of cardiovascular disease states in an accessible handbook-style to aid with the care of these patients. The Handbook of Inpatient Cardiology is an essential resource for physician hospitalists caring for cardiac patients on the medical ward in addition to cardiology physicians and trainees, affiliate providers, and students.

NORD Guide to Rare Disorders

Author : National Organization for Rare Disorders
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781730631
Total Pages : 982 pages
Book Rating : 4.7/5 (36 download)

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Book Synopsis NORD Guide to Rare Disorders by : National Organization for Rare Disorders

Download or read book NORD Guide to Rare Disorders written by National Organization for Rare Disorders and published by Lippincott Williams & Wilkins. This book was released on 2003 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: NORD Guide to Rare Disorders is a comprehensive, practical, authoritative guide to the diagnosis and management of more than 800 rare diseases. The diseases are discussed in a uniform, easy-to-follow format--a brief description, signs and symptoms, etiology, related disorders, epidemiology, standard treatment, investigational treatment, resources, and references.The book includes a complete directory of orphan drugs, a full-color atlas of visual diagnostic signs, and a Master Resource List of support groups and helpful organizations. An index of symptoms and key words offers physicians valuable assistance in finding the information they need quickly.

Primary Pulmonary Hypertension

Author : Lewis J. Rubin
Publisher : CRC Press
ISBN 13 : 9780824795054
Total Pages : 384 pages
Book Rating : 4.7/5 (95 download)

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Book Synopsis Primary Pulmonary Hypertension by : Lewis J. Rubin

Download or read book Primary Pulmonary Hypertension written by Lewis J. Rubin and published by CRC Press. This book was released on 1996-11-06 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detailing state-of-the-art developments in the various aspects of primary pulmonary hypertension (PPH), this practical reference explores the history, most current scientific concepts, and treatments of this disease. Includes new advances not yet formally published! Written by nearly 30 of the top international experts in the field, Primary Pulmonary Hypertension addresses the general histological features of the normal and hypertensive pulmonary vasculature and the pathology of PPH discusses etiological possibilities of pathogenesis, common morphological features, and findings in experimental models examines risks factors for PPH and looks separately at familial PPH and PPH in children presents an approach to the differential diagnosis of pulmonary hypertension, emphasizing the recognition of PPH elucidates the invasive and noninvasive modalities available for obtaining qualitative and quantitative hemodynamic data for the diagnosis of PPH covers a variety of therapeutic options and much more!