Pharmacology Pharmacotherapeutics

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Pharmacotherapeutics for Advanced Practice

Author : Virginia Poole Arcangelo
Publisher : LWW
ISBN 13 : 9781496319968
Total Pages : 0 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Pharmacotherapeutics for Advanced Practice by : Virginia Poole Arcangelo

Download or read book Pharmacotherapeutics for Advanced Practice written by Virginia Poole Arcangelo and published by LWW. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Be ready to prescribe and administer drugs safely and effectively--and grasp all the vitals of pharmacology--with the fully updated Pharmacotherapeutics for Advanced Practice, 4th edition. Written by pharmacology nursing experts, this easy-to-read text offers proven frameworks for treating more than 50 common diseases and disorders. Learn how to identify disorders, review possible therapies, then prescribe and monitor drug treatment, accurately. Based on current evidence and real-life patient scenarios, this is the perfect pharmacology learning guide and on-the-spot clinical resource. Absorb the key principles and practical methods for accurate prescribing and monitoring, with . . . NEW chapter on Parkinson's disease, osteoarthritis, and rheumatoid arthritis NEWand updated therapies, and updated and additional case studies, with sample questions NEW content on the impacts of the Affordable Care Act Updated chapters on complementary and alternative medicine (CAM) and pharmacogenomics Updated evidence-basedalgorithms and drugtables - Listing uses, mechanisms, adverse effects, drug interactions, contraindications, and monitoring parameters, organized by drug class; quick access to generic and trade names and dosages Quick-scan format organizes information by body system Chapter features include: Brief overview - Pathophysiology of each disorder, and relevant classes of drugs Monitoring Patient Response section - What to monitor, and when Patient Education section - Includes information on CAM for each disorder Drug Overview tables - Usual dose, contraindications and side effects, and special considerations Algorithms - Visual cues on how to approach treatment Updated Recommended Order of Treatment tables - First-, second- and third-line drug therapies for each disorder Answers to Case Study Questions for each disorder - Strengthens critical thinking skills Selecting the Most Appropriate Agentsection - The thought process for choosing an initial drug therapy Principles of Therapeuticsunit - Avoiding medication errors; pharmacokinetics and pharmacodynamics; impact of drug interactions and adverse events; principles of pharmacotherapy for pediatrics, pregnancy/lactation, and geriatrics Disorders units - Pharmacotherapy for disorders in various body systems Pharmacotherapy in Health Promotion unit - Smoking cessation, immunizations, weight management Women's Health unit - Including contraception, menopause, and osteoporosis Integrative Approach to Patient Care unit - Issues to consider when presented with more than one diagnosis Standard pharmacotherapeutics text for nurse practitioners, students, and physician assistants Ancillaries - Case Study answers, multiple choice questions and answers for every chapter, PowerPoints, Acronyms List

Pharmacology and Pharmacotherapeutics

Author : RS Satoskar
Publisher : Elsevier India
ISBN 13 : 8131257061
Total Pages : 1151 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Pharmacology and Pharmacotherapeutics by : RS Satoskar

Download or read book Pharmacology and Pharmacotherapeutics written by RS Satoskar and published by Elsevier India. This book was released on 2020-07-10 with total page 1151 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book strengthens the scientific knowledge base and promotes rational thinking among students The Medical Council of India (MCI) has introduced a competency-based curriculum in 2019, which not only lays emphasis on integration with clinical and pre-clinical subjects but also clearly states subject competencies and defines domains and levels to be achieved for each of them. In addition, it is clinically oriented and gives due importance to the self-directed learning. The duration of teaching for the subject of Pharmacology in the new curriculum has been reduced to one year with additional dedicated time to revisit it in the subsequent years. This 26th edition of Pharmacology and Pharmacotherapeutics has been revised considerably to match the demands of the new curriculum. Right from its conception, this book has used an integrated approach intertwining current knowledge of pathophysiology of the disease, pharmacology of available drugs and strategies for medical management of diseases. We have made every attempt to provide up-to-date information about the drugs while focussing on the aspects relevant to their use in clinical practice. Structured pedagogy facilitating feature-rich presentation and organization of the content, which makes it more student friendly Richly illustrated content supplemented with large number of tables and boxes - explaining physiology, complex concepts, relevant drug features and principles of pharmacotherapy Mechanisms of drug actions, explained in text and illustrated via diagrams as well as videos (animations) for better understanding and retention Key points in pharmacology and pharmacotherapy of diseases highlighted throughout the book Practical tips in this book serve as a reference guide in practice so that students can treat their patients effectively and confidently

Pharmacology and Pharmacotherapeutics

Author : RS Satoskar
Publisher : Elsevier Health Sciences
ISBN 13 : 8131249417
Total Pages : 1173 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Pharmacology and Pharmacotherapeutics by : RS Satoskar

Download or read book Pharmacology and Pharmacotherapeutics written by RS Satoskar and published by Elsevier Health Sciences. This book was released on 2017-09-23 with total page 1173 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 25th revised edition of Pharmacology and Pharmacotherapeutics continues to maintain its status as an up-to-date, accurate and reliable text for medical students as well as practicing physicians. The advances in molecular biology have significantly influenced the understanding of pathogenesis of diseases and development of newer drugs. The real challenge, however, remains in application of the available information while treating a patient. This book has always placed before the readers an integrated approach intertwining current knowledge of pathophysiology of the disease, pharmacology of available drugs and strategies for medical management of diseases. The current edition balances the complexity and simplicity of scientific content to provide students of medicine and/or pharmacy an insight into rational therapeutics. It gives several practical tips which empowers the physician to treat patients effectively and confidently. Written in an integrated fashion, Pharmacology and Pharmacotherapeutics builds up a strong foundation of scientific knowledge to guide decision making and to promote a holistic approach towards patient care in clinical practice. - Emphasis on Clinical Pharmacology in each chapter - Current guidelines for therapeutic decisions - Newer sedatives-hypnotics - Hypertension management: Updates - Advances in treatment of obesity and hyperlipidemia - Newer antiepileptics - Antiviral agents for hepatitis C - Rheumatoid arthritis: pharmacotherapy - Management of pulmonary hypertension - Newer antidiabetic drugs - Advances in immunotherapeutics - Vitamin D and calcium: Updates - Therapeutic advances for infectious diseases

Pharmacotherapy Casebook

Author : Terry L. Schwinghammer
Publisher : McGraw-Hill Medical Publishing
ISBN 13 :
Total Pages : 484 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pharmacotherapy Casebook by : Terry L. Schwinghammer

Download or read book Pharmacotherapy Casebook written by Terry L. Schwinghammer and published by McGraw-Hill Medical Publishing. This book was released on 2005 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This casebook is designed to help students develop the skills required to identify and resolve drug therapy problems through the use of patient case studies.

Pharmacotherapeutics For Advanced Practice Nurse Prescribers

Author : Teri Moser Woo
Publisher : F.A. Davis
ISBN 13 : 0803645813
Total Pages : 1417 pages
Book Rating : 4.8/5 (36 download)

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Book Synopsis Pharmacotherapeutics For Advanced Practice Nurse Prescribers by : Teri Moser Woo

Download or read book Pharmacotherapeutics For Advanced Practice Nurse Prescribers written by Teri Moser Woo and published by F.A. Davis. This book was released on 2015-08-03 with total page 1417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This exceptional text builds your knowledge of pharmacology by first providing an overview of pharmacologic principles and then teaching you how to apply those principles to clinical practice. Focusing on applying pharmacologic scientific knowledge to clinical practice, it explains diagnostic and treatment reasoning and rational drug selection, while providing useful clinical pearls from experienced practitioners.

Pharmacology and Pharmacotherapeutics

Author : R. S. Satoskar
Publisher :
ISBN 13 :
Total Pages : 846 pages
Book Rating : 4.:/5 (79 download)

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Book Synopsis Pharmacology and Pharmacotherapeutics by : R. S. Satoskar

Download or read book Pharmacology and Pharmacotherapeutics written by R. S. Satoskar and published by . This book was released on 1971 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medical Pharmacology and Therapeutics E-Book

Author : Derek G. Waller
Publisher : Elsevier Health Sciences
ISBN 13 : 0702055034
Total Pages : 741 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Medical Pharmacology and Therapeutics E-Book by : Derek G. Waller

Download or read book Medical Pharmacology and Therapeutics E-Book written by Derek G. Waller and published by Elsevier Health Sciences. This book was released on 2013-08-07 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice

Pharmacotherapeutics for Advanced Practice

Author : Virginia Poole Arcangelo
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496351843
Total Pages : 2341 pages
Book Rating : 4.4/5 (963 download)

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Book Synopsis Pharmacotherapeutics for Advanced Practice by : Virginia Poole Arcangelo

Download or read book Pharmacotherapeutics for Advanced Practice written by Virginia Poole Arcangelo and published by Lippincott Williams & Wilkins. This book was released on 2016-06-09 with total page 2341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Be ready to prescribe and administer drugs safely and effectively—and grasp all the vitals of pharmacology—with the fully updated Pharmacotherapeutics for Advanced Practice, 4th edition. Written by pharmacology nursing experts, this easy-to-read text offers proven frameworks for treating more than 50 common diseases and disorders. Learn how to identify disorders, review possible therapies, then prescribe and monitor drug treatment, accurately. Based on current evidence and real-life patient scenarios, this is the perfect pharmacology learning guide and on-the-spot clinical resource. Absorb the key principles and practical methods for accurate prescribing and monitoring, with . . . NEW chapter on Parkinson’s disease, osteoarthritis, and rheumatoid arthritis NEW and updated therapies, and updated and additional case studies, with sample questions NEW content on the impacts of the Affordable Care Act Updated chapters on complementary and alternative medicine (CAM) and pharmacogenomics Updated evidence-based algorithms and drug tables – Listing uses, mechanisms, adverse effects, drug interactions, contraindications, and monitoring parameters, organized by drug class; quick access to generic and trade names and dosages Quick-scan format organizes information by body system Chapter features include: Brief overview – Pathophysiology of each disorder, and relevant classes of drugs Monitoring Patient Response section – What to monitor, and when Patient Education section – Includes information on CAM for each disorder Drug Overview tables – Usual dose, contraindications and side effects, and special considerations Algorithms – Visual cues on how to approach treatment Updated Recommended Order of Treatment tables – First-, second- and third-line drug therapies for each disorder Answers to Case Study Questions for each disorder – Strengthens critical thinking skills Selecting the Most Appropriate Agent section – The thought process for choosing an initial drug therapy Principles of Therapeutics unit – Avoiding medication errors; pharmacokinetics and pharmacodynamics; impact of drug interactions and adverse events; principles of pharmacotherapy for pediatrics, pregnancy/lactation, and geriatrics Disorders units – Pharmacotherapy for disorders in various body systems Pharmacotherapy in Health Promotion unit – Smoking cessation, immunizations, weight management Women’s Health unit – Including contraception, menopause, and osteoporosis Integrative Approach to Patient Care unit – Issues to consider when presented with more than one diagnosis Standard pharmacotherapeutics text for nurse practitioners, students, and physician assistants Ancillaries – Case Study answers, multiple choice questions and answers for every chapter, PowerPoints, Acronyms List

Pharmacotherapeutics for Advanced Practice

Author : Virginia Poole Arcangelo
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975160606
Total Pages : 1989 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Pharmacotherapeutics for Advanced Practice by : Virginia Poole Arcangelo

Pharmacology and Pharmacotherapeutics - E-Book

Author : RS Satoskar
Publisher : Elsevier Health Sciences
ISBN 13 : 8131243710
Total Pages : 1171 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Pharmacology and Pharmacotherapeutics - E-Book by : RS Satoskar

Download or read book Pharmacology and Pharmacotherapeutics - E-Book written by RS Satoskar and published by Elsevier Health Sciences. This book was released on 2015-07-30 with total page 1171 pages. Available in PDF, EPUB and Kindle. Book excerpt: A classic Pharmacology book trusted equally by students and practicing physicians for its up-to-date, accurate and reliable text, which has always placed before the readers an integrated approach intertwining current knowledge of pathophysiology of the disease, pharmacology of available drugs and strategies for medical management of diseases.• Trusted Pharmacology book with emphasis on pathophysiology, clinical pharmacology and therapeutics, presenting information in integrated manner. • Up-to-date information supplemented with tables and diagrams, having: - therapy of important diseases presented in boxes. - current guidelines to support therapeutic decisions - tips for practising physicians. • Uses integrated approach intertwining current knowledge of pathophysiology of the disease, pharmacology of available drugs and strategies for medical management of diseases. • Balances the complexity and simplicity of scientific content to provide students of medicine and/or pharmacy an insight into rational therapeutics.

Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, Fourth Edition

Author : Janet L. Stringer
Publisher : McGraw Hill Professional
ISBN 13 : 0071769420
Total Pages : 254 pages
Book Rating : 4.0/5 (717 download)

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Book Synopsis Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, Fourth Edition by : Janet L. Stringer

Download or read book Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, Fourth Edition written by Janet L. Stringer and published by McGraw Hill Professional. This book was released on 2011-03-11 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: A time-saving, stress-reducing approach to learning the essential concepts of pharmacology Great for USMLE review! "This could be a very useful tool for students who struggle with understanding the most basic concepts in pharmacology for course and licensure examinations. 3 Stars."--Doody's Review Service Basic Concepts in Pharmacology provides you with a complete framework for studying -– and understanding -- the fundamental principles of drug actions. With this unique learning system, you’ll be able to identify must-know material, recognize your strengths and weaknesses, minimize memorization, streamline your study, and build your confidence. Basic Concepts in Pharmacology presents drugs by class, details exactly what you need to know about each class, and reinforces key concepts and definitions. With this innovative text you’ll be able to: Recognize the concepts you truly must know before moving on to other material Understand the fundamental principles of drug actions Organize and condense the drug information you must remember Review key information, which is presented in boxes, illustrations, and tables Identify the most important drugs in each drug class Seven sections specifically designed to simplify the learning process and help you gain an understanding of the most important concepts: General Principles Drugs That Affect the Autonomic Nervous System Drugs That Affect the Cardiovascular System Drugs That Act on the Central Nervous System Chemotherapeutic Agents Drugs That Affect the Endocrine System Miscellaneous Drugs (Includes Toxicology and Poisoning)

Pharmacology And Pharmacotherapeutics (New Revised 21 St Ed.)

Author : R. S. Satoskar
Publisher : Popular Prakashan
ISBN 13 : 9788179915271
Total Pages : 1150 pages
Book Rating : 4.9/5 (152 download)

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Book Synopsis Pharmacology And Pharmacotherapeutics (New Revised 21 St Ed.) by : R. S. Satoskar

Download or read book Pharmacology And Pharmacotherapeutics (New Revised 21 St Ed.) written by R. S. Satoskar and published by Popular Prakashan. This book was released on 1988 with total page 1150 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advanced Pharmacology for Prescribers

Author : Brent Q. Luu, PharmD, BCPS, BCACP
Publisher : Springer Publishing Company
ISBN 13 : 0826195474
Total Pages : 659 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Advanced Pharmacology for Prescribers by : Brent Q. Luu, PharmD, BCPS, BCACP

Download or read book Advanced Pharmacology for Prescribers written by Brent Q. Luu, PharmD, BCPS, BCACP and published by Springer Publishing Company. This book was released on 2021-01-13 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delivers the critical information primary care providers need to be thoroughly informed prescribers This unique resource—an evidence-based pharmacology text and reference for advanced practice students and clinicians—guides users in analyzing the pharmacological foundations of drug therapy and fosters the development of sound clinical judgment in determining the appropriate medication for every patient across the lifespan. Targeting the specific needs of APRN and PA students and clinicians, the text is a “bridge” between standard, lengthy pharmacology texts and quick pocket references that lack information regarding key pharmacotherapy principles. Featuring an applied therapeutic approach to major disorders and their pharmacologic treatment, the book examines how medications act on the body and visa versa, while teaching the rationale for using specific therapeutic agents or drug classes. Each chapter includes case studies that apply the concepts discussed, relevant diagnostic studies, applicable guidelines, genomics, and important lifespan considerations. Of special interest is a chapter on pharmacogenetics explaining the basic principles underlying our current understanding of genetic variations in response to pharmacotherapy and adverse drug reactions. Easily digestible chapters include objectives and review questions. Ancillary resources include an instructor manual with learning objectives, chapter summaries, and case studies; chapter PowerPoint slides; test bank; and image bank. Key Features: Delivers an applied, evidence-based foundation on the basic science underlying prescribing Targets the specific needs of APRN and PA students and professionals and related healthcare providers Provides clinical decision-making tools and principles to support sound prescribing judgment Focuses on synthesizing drugs to manage commonly occurring disorders Includes strategies for addressing the needs of specific populations throughout the lifespan Includes abundant case studies illuminating key concepts Includes a robust instructor manual with learning objectives, chapter summaries, and case studies; PowerPoint slides; test bank; and image bank. Purchase includes access to the eBook for use on most mobile devices or computers.

Pharmacology and Pharmacotherapeutics, 26e

Author : R. S. Satoskar
Publisher :
ISBN 13 : 9788131256954
Total Pages : 0 pages
Book Rating : 4.2/5 (569 download)

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Book Synopsis Pharmacology and Pharmacotherapeutics, 26e by : R. S. Satoskar

Download or read book Pharmacology and Pharmacotherapeutics, 26e written by R. S. Satoskar and published by . This book was released on 2020-07-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book strengthens the scientific knowledge base and promotes rational thinking among students The Medical Council of India (MCI) has introduced a competency-based curriculum in 2019, which not only lays emphasis on integration with clinical and pre-clinical subjects but also clearly states subject competencies and defines domains and levels to be achieved for each of them. In addition, it is clinically oriented and gives due importance to the self-directed learning. The duration of teaching for the subject of Pharmacology in the new curriculum has been reduced to one year with additional dedicated time to revisit it in the subsequent years. This 26th edition of Pharmacology and Pharmacotherapeutics has been revised considerably to match the demands of the new curriculum. Right from its conception, this book has used an integrated approach intertwining current knowledge of pathophysiology of the disease, pharmacology of available drugs and strategies for medical management of diseases. We have made every attempt to provide up-to-date information about the drugs while focussing on the aspects relevant to their use in clinical practice. Structured pedagogy facilitating feature-rich presentation and organization of the content, which makes it more student friendly Richly illustrated content supplemented with large number of tables and boxes - explaining physiology, complex concepts, relevant drug features and principles of pharmacotherapy Mechanisms of drug actions, explained in text and illustrated via diagrams as well as videos (animations) for better understanding and retention Key points in pharmacology and pharmacotherapy of diseases highlighted throughout the book Practical tips in this book serve as a reference guide in practice so that students can treat their patients effectively and confidently What's New Thoroughly revised content, fully in line with the New CBME Curriculum Knowledge-related competencies labelled within the text Drug information fully updated, presented in crisp and integrated manner Illustrations increased, converted to multicolour graphics Core points and therapeutics highlighted with coloured backgrounds in the text Widely reviewed and updated text, in line with feedback from faculty members and students Over 100 flow charts of drug classification added, available as a separate section within the book Important Additions/Updations Management of ADRs and drug interactions Epilepsy management - updated Psycopharmacology - clinically oriented Prostaglandin uses - at a glance Updated treatment guidelines for asthma and COPD Newer antimicrobials, beta lactamase inhibitors and antibiotic stewardship programme Current guidelines for TB management STD prophylaxis Drug therapy of HBV, HCV and coronaviruses Metronomic chemotherapy Recent trends in management of diabetes mellitus Immunopharmacology - simplified

Critical Care Pharmacotherapeutics

Author : Thomas J. Johnson
Publisher : Jones & Bartlett Publishers
ISBN 13 : 1449604781
Total Pages : 438 pages
Book Rating : 4.4/5 (496 download)

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Book Synopsis Critical Care Pharmacotherapeutics by : Thomas J. Johnson

Download or read book Critical Care Pharmacotherapeutics written by Thomas J. Johnson and published by Jones & Bartlett Publishers. This book was released on 2013 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical Care Pharmacotherapeutics presents information on the fundamentals of critical care practice from a pharmacist's point of view. This accessible text is an excellent introduction to critical care pharmacy. Pharmacy students, residents, and new pharmacists will learn about the medications used and approaches to pharmaceutical care for the critically ill patient. This text is also a helpful reference for students during an ICU advanced practice experience or for a pharmacy resident during an ICU rotation.

Essentials of Pharmacotherapeutics

Author : F S K Barar
Publisher : S. Chand Publishing
ISBN 13 : 8121904447
Total Pages : 639 pages
Book Rating : 4.1/5 (219 download)

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Book Synopsis Essentials of Pharmacotherapeutics by : F S K Barar

Download or read book Essentials of Pharmacotherapeutics written by F S K Barar and published by S. Chand Publishing. This book was released on 2000-10 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and well-written book presents the fundamental concepts of Pharmacotherapeutics, aiming at the safe and effective use of drugs in the treatment of disease. It is interdisciplinary in its approach and provides a basis for understanding the actions and uses of drugs in man. It is written in a simple and easy-to-understand language. The text is divided into sixteen chapters

Pharmacotherapeutics for Advanced Practice

Author : Virginia Poole Arcangelo
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781757843
Total Pages : 988 pages
Book Rating : 4.7/5 (578 download)

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Book Synopsis Pharmacotherapeutics for Advanced Practice by : Virginia Poole Arcangelo

Download or read book Pharmacotherapeutics for Advanced Practice written by Virginia Poole Arcangelo and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: This advanced pharmacotherapeutics text for nurse practitioners and physician assistants offers guidelines on prescribing drugs for over 50 common diseases and disorders. The book is organized by disorder rather than drug class and includes algorithms and case studies that illustrate critical thinking aspects of prescribing, such as drug selection, lifespan considerations, therapeutic drug monitoring, adverse reactions, unexpected outcomes, and when to change therapy. This Second Edition has new chapters on oncologic disorders and complementary and alternative medicines. Improved case studies reflect more realistic practice issues in decision-making. Additional areas addressed include food-drug interactions, dietary considerations, and concerns regarding geriatric patients.