Pharmacological Potential Of Selected Natural Compounds In The Control Of Parasitic Diseases

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Pharmacological Potential of Selected Natural Compounds in the Control of Parasitic Diseases

Author : Gabriela Hrckova
Publisher : Springer Science & Business Media
ISBN 13 : 3709113253
Total Pages : 135 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Pharmacological Potential of Selected Natural Compounds in the Control of Parasitic Diseases by : Gabriela Hrckova

Download or read book Pharmacological Potential of Selected Natural Compounds in the Control of Parasitic Diseases written by Gabriela Hrckova and published by Springer Science & Business Media. This book was released on 2012-12-13 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: The natural world with a large number of terrestrial and marine plants and lower organisms is a great source of bioactive compounds historically used as remedies in various diseases. Within the last decade, such compounds became more attractive targets for pharmacologists and the pharmaceutical industry in drug development projects. This volume presents the pharmacological potential of chemically defined natural compounds obtained from plants, fungi, algae and cyanobacteria with antiparasitic activity, that have been tested against various endo-parasitic protozoan and helminth species. Additionally, the advantages of combined therapy using antiparasitic drugs and natural compounds with selected specific activity are reviewed and explained in the context of host pathology and immunosuppression induced by the parasites. The conclusions of this new book give suggestions for further non-empirical drug development and discuss perspectives of alternative approaches to therapy of parasitic diseases.

Drug Development for Malaria

Author : Pravin Kendrekar
Publisher : John Wiley & Sons
ISBN 13 : 3527830596
Total Pages : 404 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Drug Development for Malaria by : Pravin Kendrekar

Download or read book Drug Development for Malaria written by Pravin Kendrekar and published by John Wiley & Sons. This book was released on 2022-08-09 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Development for Malaria Provides readers with first-hand advice for the development of novel antimalarial drugs This book provides a systematic overview of antimalarial drug development and presents a wealth of data and insight from drug developers across three continents, including many from countries where the disease is endemic. Throughout, the contributions have been written with the drug developer in mind, highlighting challenges but also opportunities for the successful development of effective antimalarial drugs. Case studies and method-oriented chapters provide an abundance of practical first-hand advice on how to successfully develop an antimalarial drug. Key topics covered in the book include: The performance of current drugs and therapies, the influence of formulation and targeted delivery, and strategies to overcome drug resistance. Technologies and approaches for development of novel drugs, such as assays, computer-aided drug design, known and potential drug targets, and natural sources for novel antimalarial compounds Vaccination as an alternative to drug therapy For chemists and other professionals working in industries related to medicine and pharmaceuticals, this book provides a completely comprehensive overview of the current state of novel antimalarial drugs and how they can be developed in an efficient and cost-effective manner.

Ethnoveterinary Medicine

Author : Lyndy J. McGaw
Publisher : Springer Nature
ISBN 13 : 303032270X
Total Pages : 437 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Ethnoveterinary Medicine by : Lyndy J. McGaw

Download or read book Ethnoveterinary Medicine written by Lyndy J. McGaw and published by Springer Nature. This book was released on 2019-12-31 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of a complementary approach to animal health is highlighted in this book, with core themes encompassing reviews of traditional veterinary medicine for common diseases afflicting livestock, as well as local practices in different areas of the world. The book includes chapters on ethnoveterinary medicine used to prevent and treat ticks and tick-borne diseases, infectious diseases and parasites. Ethnoveterinary practices in parts of the world which have not been comprehensively reviewed before are highlighted, including Estonia, Belarus and the Maghreb - the north-western tip of Africa. A fascinating account of African ethnoveterinary medicine and traditional husbandry practices is provided by a veteran in the field with a wealth of practical experience in the area. Neglected areas of research involve the relationship of ethnoveterinary medicine with environmental, ethical, cultural and gender aspects, and leading experts explore these issues. The book is intended to provide an informative compilation of current research and future prospects in ethnoveterinary medicine, which hopes to inform and encourage investigations in new directions. Sustainable development requires a concerted effort to combine indigenous knowledge systems with scientific research to improve animal health. This is the case not only in rural areas where access to orthodox veterinary health care may be limited, but also against the backdrop of antibiotic resistance and increased demand for alternative and complementary therapies to enhance the health of both production and companion animals. Students, academics and veterinary professionals will find this book a useful addition to knowledge on present and future aspects of ethnoveterinary research.

Chemistry, Biological Activities and Therapeutic Applications of Medicinal Plants in Ayurveda

Author : Augustine Amalraj
Publisher : Royal Society of Chemistry
ISBN 13 : 1839164034
Total Pages : 461 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Chemistry, Biological Activities and Therapeutic Applications of Medicinal Plants in Ayurveda by : Augustine Amalraj

Download or read book Chemistry, Biological Activities and Therapeutic Applications of Medicinal Plants in Ayurveda written by Augustine Amalraj and published by Royal Society of Chemistry. This book was released on 2022-11-16 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ayurvedic medicine and its components have been well described in the past but this book represents a comprehensive source on the biochemistry and mechanisms of pharmacological effect of ayurvedic sources. This book is a valuable resource for researchers in natural products and alternative sources of bioactive compounds in drug discovery.

The Bitter Gourd Genome

Author : Chittaranjan Kole
Publisher : Springer Nature
ISBN 13 : 3030150623
Total Pages : 148 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis The Bitter Gourd Genome by : Chittaranjan Kole

Download or read book The Bitter Gourd Genome written by Chittaranjan Kole and published by Springer Nature. This book was released on 2020-01-29 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focusing on the bitter gourd genome is the first comprehensive compilation of knowledge on the botany, cytogenetical analysis, genetic resources and diversity, traditional breeding, tissue culture and genetic transformation, whole genome sequencing and comparative genomics in the Cucurbitaceae family. It discusses the biochemical profile of the bioactives present in this horticultural crop, used both as a vegetable and as a medicine, and also addresses sex determination in bitter gourd. Written by respected international experts, the book is useful to students, teachers and scientists in academia, as well as seed companies and pharmaceutical industries.

Drug Development for Parasite-induced Diarrheal Diseases

Author : Anjan Debnath
Publisher : Frontiers Media SA
ISBN 13 : 2889452484
Total Pages : 179 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Drug Development for Parasite-induced Diarrheal Diseases by : Anjan Debnath

Download or read book Drug Development for Parasite-induced Diarrheal Diseases written by Anjan Debnath and published by Frontiers Media SA. This book was released on 2017-08-25 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the top four contributors to the global burden of disease is diarrheal infections. Intestinal parasites are major causes of morbidity and mortality associated with diarrheal diseases in both the developed and developing world. Amebiasis is responsible for 50 million cases of invasive disease and 70,000 deaths annually in the world. Giardiasis has an estimated worldwide prevalence of 280 million cases annually. In developed countries, Giardia lamblia infects about 2% of adults and 6-8% of children. The prevalence of G. lamblia infection is generally higher in developing countries, ranging from 3% to 90%. Furthermore, giardial infections contribute substantially to the 2.5 million annual deaths from diarrheal disease. In Asia, Africa, and Latin America, about 500,000 new giardiasis cases are reported each year. Cryptosporidium accounts for 20% and 9% of diarrheal episodes in children in developing and developed countries, respectively. Infection with Cryptosporidium can be chronic and especially debilitating in immunosuppressed individuals and malnourished children. A recent study to measure disease burden, based on disability-adjusted life years (DALYs), found that cryptosporidiosis and amebiasis produce about 10.6 million DALYs. This exceeds the DALYs of any helminth infection currently being targeted by the World Health Organization for preventive chemotherapy. Because of its link with poverty, Giardia and Cryptosporidium were included in the WHO Neglected Diseases Initiative in 2004. E. histolytica, G. lamblia, and C. parvum have been listed by the National Institutes of Health (NIH) as category B priority biodefense pathogens due to low infectious dose and potential for dissemination through compromised food and water supplies in the United States. Despite the prevalence of amebiasis, giardiasis, and cryptosporidiosis there are no vaccines or prophylactic drugs. The first-line drugs for invasive amebiasis and giardiasis chemotherapy are nitroimidazoles, with the prototype, metronidazole, being the most common drug used worldwide. Metronidazole has been shown to be both mutagenic in a microbiological system and carcinogenic to rodents, and frequently causes gastrointestinal side effects. In spite of the efficacy of nitroimidazole drugs, treatment failures in giardiasis occur in up to 20% of cases. Clinical resistance of G. lamblia to metronidazole is proven and cross resistance is a concern with all commonly used antigiardial drugs. Nitazoxanide, the only FDA-approved drug for the treatment of cryptosporidiosis, is effective in the treatment of immunocompetent patients and partially effective for immunosuppressed patients. Therefore, it is critical to search for more effective drugs to treat amebiasis, giardiasis, and cryptosporidiosis. This Research Topic for Frontiers in Microbiology will explore the recent progress in drug development for parasitic diarrheal diseases. This includes an understanding of drug resistance mechanisms. We would also welcome submissions on the drug development for other diarrheal parasites. We hope that this research topic will include a comprehensive survey of various attempts by the parasitology research community to create effective drugs for these diseases.

Advances in Parasitology

Author :
Publisher : Academic Press
ISBN 13 : 0323850898
Total Pages : 290 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Advances in Parasitology by :

Download or read book Advances in Parasitology written by and published by Academic Press. This book was released on 2021-01-20 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Parasitology, Volume 111, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history. Chapters in this update include Taking the strain out of onchocerciasis: a reanalysis of blindness and transmission data does not support the existence of a savanna blinding strain of onchocerciasis in West Africa, Enterocytozoon bieneusi of animals, Taenia solium taeniasis/cysticercosis, Genomic analysis reveals predominant clonality and progressive evolution at all evolutionary scales in eukaryotic pathogens, HTLV-I and Strongyloides: the worm lurking beneath, and more. Informs and updates on all the latest developments in the field of parasitology Includes medical studies of parasites of major influence Features reviews of more traditional areas, such as zoology, taxonomy, and life history, which help shape current thinking and applications

Natural Remedies in the Fight Against Parasites

Author : Hanem Khater
Publisher : BoD – Books on Demand
ISBN 13 : 953513289X
Total Pages : 250 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Natural Remedies in the Fight Against Parasites by : Hanem Khater

Download or read book Natural Remedies in the Fight Against Parasites written by Hanem Khater and published by BoD – Books on Demand. This book was released on 2017-07-12 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book emphasizes past and current research efforts about principles of natural control of major parasites affecting humans, animals, and crops. Each chapter is a complete and integrated subject that presents a problem and confers on the safe alternatives to chemicals. This book discusses and updates information about three major topics of natural remedies. The first topic is represented in a chapter outlining important information on biological control of parasites, the second topic is represented in three chapters dealing with botanicals as promising antiparasitic agents, and the last four chapters deal with miscellaneous control strategies against parasites. This easily readable book is designed precisely for students as well as professors linked with the field of parasitic control. We enhanced words with breathing areas in the form of graphical abstracts, figures, photographs, and tables.

WIPO Re:Search - Collaborating to Mobilize the Power of Intellectual Property for Global Health

Author : World Intellectual Property Organization
Publisher : WIPO
ISBN 13 :
Total Pages : 4 pages
Book Rating : 4./5 ( download)

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Book Synopsis WIPO Re:Search - Collaborating to Mobilize the Power of Intellectual Property for Global Health by : World Intellectual Property Organization

Download or read book WIPO Re:Search - Collaborating to Mobilize the Power of Intellectual Property for Global Health written by World Intellectual Property Organization and published by WIPO. This book was released on 2018-11-15 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt: WIPO Re:Search aims to catalyze the development of medical products for neglected tropical diseases, malaria and tuberculosis through innovative research partnerships and knowledge sharing.

Natural Product Based Drug Discovery Against Human Parasites

Author : Archana Singh
Publisher : Springer Nature
ISBN 13 : 9811996059
Total Pages : 602 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Natural Product Based Drug Discovery Against Human Parasites by : Archana Singh

Download or read book Natural Product Based Drug Discovery Against Human Parasites written by Archana Singh and published by Springer Nature. This book was released on 2024-01-01 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews current and novel treatment strategies against human parasites, including protozoans and helminths, using natural products. The initial chapters summarize the conventional treatment strategies and natural-product based therapeutics against these parasites. It discusses biochemical tools and techniques for the discovery of natural product based drugs against human parasites. The book also covers the ingenious and innovative mechanisms to achieve drug resistance by the protozoan parasites and strategies to overcome the resistance. It entails mechanistic insight into the modulation of host immune responses to delay or inhibit parasite clearance and explores host-pathogen interactions that mediate immunity against subsequent parasite challenge. In turn, the volume helps in understanding the immunobiology of the parasites and tools to identify candidate vaccine antigens and novel delivery systems against the protozoan parasites. Lastly, it explores the role of advanced methods, including nanotechnology, marine bioprospecting, and microorganisms-derived biochemicals against the protozoan parasites. This book is useful for students and researchers of pharmacology, parasitology, zoology and other allied fields.

Tribology and Dynamics of Engine and Powertrain

Author : Homer Rahnejat
Publisher : Elsevier
ISBN 13 : 1845699939
Total Pages : 1048 pages
Book Rating : 4.8/5 (456 download)

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Book Synopsis Tribology and Dynamics of Engine and Powertrain by : Homer Rahnejat

Download or read book Tribology and Dynamics of Engine and Powertrain written by Homer Rahnejat and published by Elsevier. This book was released on 2010-09-30 with total page 1048 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tribology, the science of friction, wear and lubrication, is one of the cornerstones of engineering’s quest for efficiency and conservation of resources. Tribology and dynamics of engine and powertrain: fundamentals, applications and future trends provides an authoritative and comprehensive overview of the disciplines of dynamics and tribology using a multi-physics and multi-scale approach to improve automotive engine and powertrain technology. Part one reviews the fundamental aspects of the physics of motion, particularly the multi-body approach to multi-physics, multi-scale problem solving in tribology. Fundamental issues in tribology are then described in detail,from surface phenomena in thin-film tribology, to impact dynamics, fluid film and elastohydrodynamic lubrication means of measurement and evaluation. These chapters provide an understanding of the theoretical foundation for Part II which includes many aspects of the physics of motion at a multitude of interaction scales from large displacement dynamics to noise and vibration tribology, all of which affect engines and powertrains. Many chapters are contributed by well-established practitioners disseminating their valuable knowledge and expertise on specific engine and powertrain sub-systems. These include overviews of engine and powertrain issues, engine bearings, piston systems, valve trains, transmission and many aspects of drivetrain systems. The final part of the book considers the emerging areas of microengines and gears as well as nano-scale surface engineering. With its distinguished editor and international team of academic and industry contributors, Tribology and dynamics of engine and powertrain is a standard work for automotive engineers and all those researching NVH and tribological issues in engineering. Reviews fundamental aspects of physics in motion, specifically the multi-body approach to multi physics Describes essential issues in tribology from surface phenomena in thin film tribology to impact dynamics Examines specific engine and powertrain sub-systems including engine bearings, piston systems and value trains

Comprehensive Natural Products II

Author :
Publisher : Elsevier
ISBN 13 : 0080453821
Total Pages : 7944 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Comprehensive Natural Products II by :

Download or read book Comprehensive Natural Products II written by and published by Elsevier. This book was released on 2010-03-05 with total page 7944 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas among the established natural products research community—which includes chemists, biochemists, biologists, botanists, and pharmacologists Informs and inspires students and newcomers to the field with accessible content in a range of delivery formats Includes 100% new content, with more than 6,000 figures (1/3 of these in color) and 40,000 references to the primary literature, for a thorough examination of the field Highlights new research and innovations concerning living organisms and their distinctive role in our understanding and improvement of human health, genomics, ecology/environment, and more Adds to the rich body of work that is the first edition, which will be available for the first time in a convenient online format giving researchers complete access to authoritative Natural Products content

Viral, Parasitic, Bacterial, and Fungal Infections

Author : Debasis Bagchi
Publisher : Academic Press
ISBN 13 : 0323898009
Total Pages : 980 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Viral, Parasitic, Bacterial, and Fungal Infections by : Debasis Bagchi

Download or read book Viral, Parasitic, Bacterial, and Fungal Infections written by Debasis Bagchi and published by Academic Press. This book was released on 2022-10-15 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral, Parasitic, Bacterial, and Fungal Infections: Antimicrobial, Host Defense, and Therapeutic Strategies highlight diverse types of infections, including viral, bacterial, parasitic, fungal, and the therapeutic efficacy of antibiotics, antivirals, antifungals and other medications, nutraceuticals, and phytotherapeutics. This book addresses the molecular, pathophysiological, and cellular pathways involved in the process of infection. It also examines the host defense mechanisms modulated by innate and adaptive immunity. The book starts off with an introduction, which includes etiology, pathophysiology, and diagnosis of infections. It then goes on to cover a wide spectrum of salient features involved in viral, bacterial, parasitic, and fungal infections and effective therapeutic strategies. In addition, there is a complete section of eight chapters elaborating the detailed aspects of COVID-19 infections, Mucormycosis, Omicron, and strategic vaccines and therapeutics. The book further goes on to discuss novel antibiotics, vaccines, bromhexine, boron compounds, phytotherapeutics, and aspects on boosting immune competence. Contributed by experts in the fields of viral, parasitic, bacterial, and fungal infections, the book comprehensively details the various types of infections such as herpes and COVID-19, their molecular mechanisms, and treatment strategies for those engaged in the research of infectious diseases. Details the pathophysiology of various classes of infections Examines mechanisms of pathogenesis, immunity, and therapeutics in bacterial, viral, and eukaryotic infectious diseases Discusses various aspects on herpes, COVID-19 infections, Mucormycosis, Omicron, vaccines, and therapeutics Covers the salient features on zoonosis, prion disease, and diabetic foot infections Provides therapeutic strategies of using new antibiotics, vaccines, bromhexine, boron compounds, structurally diverse phytotherapeutics, immune enhancers, and other modalities for treating infections

Cellular and Molecular Basis in Parasitic Diseases Control: Research Trends

Author : Qingfeng Zhang
Publisher : Frontiers Media SA
ISBN 13 : 2889760944
Total Pages : 536 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Cellular and Molecular Basis in Parasitic Diseases Control: Research Trends by : Qingfeng Zhang

Download or read book Cellular and Molecular Basis in Parasitic Diseases Control: Research Trends written by Qingfeng Zhang and published by Frontiers Media SA. This book was released on 2022-05-04 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research Awards Index

Author :
Publisher :
ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomedical Index to PHS-supported Research

Author :
Publisher :
ISBN 13 :
Total Pages : 866 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Biomedical Index to PHS-supported Research by :

Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1990 with total page 866 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Smart Sensors and MEMS

Author : S Nihtianov
Publisher : Woodhead Publishing
ISBN 13 : 0081020562
Total Pages : 604 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Smart Sensors and MEMS by : S Nihtianov

Download or read book Smart Sensors and MEMS written by S Nihtianov and published by Woodhead Publishing. This book was released on 2018-03-09 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart Sensors and MEMS: Intelligent Devices and Microsystems for Industrial Applications, Second Edition highlights new, important developments in the field, including the latest on magnetic sensors, temperature sensors and microreaction chambers. The book outlines the industrial applications for smart sensors, covering direct interface circuits for sensors, capacitive sensors for displacement measurement in the sub-nanometer range, integrated inductive displacement sensors for harsh industrial environments, advanced silicon radiation detectors in the vacuum ultraviolet (VUV) and extreme ultraviolet (EUV) spectral range, among other topics. New sections include discussions on magnetic and temperature sensors and the industrial applications of smart micro-electro-mechanical systems (MEMS). The book is an invaluable reference for academics, materials scientists and electrical engineers working in the microelectronics, sensors and micromechanics industry. In addition, engineers looking for industrial sensing, monitoring and automation solutions will find this a comprehensive source of information. Contains new chapters that address key applications, such as magnetic sensors, microreaction chambers and temperature sensors Provides an in-depth information on a wide array of industrial applications for smart sensors and smart MEMS Presents the only book to discuss both smart sensors and MEMS for industrial applications