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Author : Katrin Kierdorf
Publisher : Frontiers Media SA
ISBN 13 : 2889714039
Total Pages : 178 pages
Book Rating : 4.8/5 (897 download)
Download or read book Deciphering Phagocyte Functions across Different Species written by Katrin Kierdorf and published by Frontiers Media SA. This book was released on 2021-09-29 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. Paul Robinson
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 408 pages
Book Rating : 4.3/5 (91 download)
Download or read book Phagocyte Function written by J. Paul Robinson and published by Wiley-Liss. This book was released on 1998-06-09 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: First volume in this new unnumbered series addressing cytometric methods. Covers the basic concepts through to the clinical applications necessary for evaluation and diagnosis, including flow cytometry, confocal microscopy, and image analysis. For clinical and biomedical researchers.
Author : F. Rossi
Publisher : Springer Science & Business Media
ISBN 13 : 146848088X
Total Pages : 685 pages
Book Rating : 4.4/5 (684 download)
Download or read book Biochemistry and Function of Phagocytes written by F. Rossi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume collects the papers presented at the "Second Euro pean Conference on Phagocytic Leucocytes" which was held in Trieste, September 15-18, 1980. The Conference was the continuation of the thread of a discourse initiated with the "First European Conference on Phagocytic Leucocytes," which was held also in Trieste in 1976. In fact, in both Conferences the biochemical aspects of the basic functions of phagocytes--that is movement, metabolism, secretion, and bactericidal activity--were mainly emphasized. In the Second Confer ence, two additional subjects were also dealt with, and those are the tumoricidal activity of phagocytes and the clinical aspects of phagocyte functions. In connection with the latter subject a "Round Table on the Clinical Application of Leucocyte Function Tests" was held during the Conference, and the proceedings are reported in this book in the hope that they may be useful to those who are interested in the relationship between phagocytes and diseases. The number of papers which are being published concerning the phagocytic process is such that one wonders whether publication of a new book in this field is necessary. However, the philosophy which inspired the edi ting of this book differs from that underlying publication of origi nal articles in scientific journals. We started from the common notion that the real progress of our knowledge is not necessarily proportional to the amount of published material in that specific field.
Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Margaret Ackerman
Publisher : Academic Press
ISBN 13 : 0123948185
Total Pages : 376 pages
Book Rating : 4.1/5 (239 download)
Download or read book Antibody Fc written by Margaret Ackerman and published by Academic Press. This book was released on 2013-08-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology. Antibodies represent the correlate of protection for numerous vaccines and are the most rapidly growing class of drugs, with applications ranging from cancer and infectious disease to autoimmunity. Researchers have long understood the variable domain of antibodies, which are responsible for antigen recognition, and can provide protection by blocking the function of their target antigen. However, recent developments in our understanding of the protection mediated by antibodies have highlighted the critical nature of the antibody constant, or Fc domain, in the biological activity of antibodies. The Fc domain allows antibodies to link the adaptive and innate immune systems, providing specificity to a wide range of innate effector cells. In addition, they provide a feedback loop to regulate the character of the immune response via interactions with B cells and antigen-presenting cells. Clarifies the different mechanisms of IgG activity at the level of the different model systems used, including human genetic, mouse, and in vitro Covers the role of antibodies in cancer, infectious disease, and autoimmunity and in the setting of monoclonal antibody therapy as well as naturally raised antibodies Color illustrations enhance explanations of the immune system
Author : Xinjiang Lu
Publisher : Frontiers Media SA
ISBN 13 : 2889664384
Total Pages : 187 pages
Book Rating : 4.8/5 (896 download)
Download or read book The Function of Phagocytes in Non-Mammals written by Xinjiang Lu and published by Frontiers Media SA. This book was released on 2021-02-02 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Carlo Mauri
Publisher : Pergamon
ISBN 13 :
Total Pages : 672 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Biology of Phagocytes in Health and Disease written by Carlo Mauri and published by Pergamon. This book was released on 1987 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents an up-to-date review of the advances being made in all aspects of phagocyte biology. The papers presented cover the nature and chemical properties of the phagocyte, its functions and movements in the body, and how it interacts with other cells in its role as part of the immune system.
Author : F Rossi
Publisher : Springer
ISBN 13 : 9781468480894
Total Pages : 716 pages
Book Rating : 4.4/5 (88 download)
Download or read book Biochemistry and Function of Phagocytes written by F Rossi and published by Springer. This book was released on 2014-01-15 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Davide Malagoli
Publisher : Academic Press
ISBN 13 : 012802013X
Total Pages : 384 pages
Book Rating : 4.1/5 (28 download)
Download or read book The Evolution of the Immune System written by Davide Malagoli and published by Academic Press. This book was released on 2016-05-24 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors. Helps the reader gain a modern idea of the evolution of the immune systems in pluricellular organisms Provides a complete overview of the most studied and hot topics in comparative and evolutionary immunology Reflects the organisation of the immune system (cell-based, humoral [innate], humoral [adaptive]) without introducing further and misleading levels of organization Brings concepts and ideas on the evolution of the immune system to a wide readership
Author : R. van Furth
Publisher : Springer Science & Business Media
ISBN 13 : 9400950209
Total Pages : 792 pages
Book Rating : 4.4/5 (9 download)
Download or read book Mononuclear Phagocytes written by R. van Furth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixteen years have passed since the first Leiden Conference on Mononuclear Phagocytes. That first meeting led to new nomenclature, i. e. , the Mononuclear Phagocytes System (MPS), which was published in the Bulletin of the World Health Organization (R. van Furth, et aI. , Bull. WHO, 1972, 46: 845-852). The paradigm of the MPS has the advantage of being much more consistent than the Reticuloendothelial System (RES) (L. Aschoff, Ergebn. Inn. Med. Kinderheilk. 1924, 26:1), because cells with similar characteristics can be classified in the same category. The essence ota new concept is, according to Popper, that it must be susceptible to falsification. This has been attempted several times for the MPS by those who adhere to the RES. However, in biology no one can be certain of truth. Any theory must be based on experimental observations and/or theoretical consider ations and both should be presented in such a way that others can try to refute it, then or later. One may have a theoretical or a pragmatic preference for a theory which at a given time is regarded as possibly truc, but later it may be shown to be false. In other words, what we present in this volume is regarded as true at this moment, but others may consider it as not true and try to disprove it. Controversies often stimulate new research.
Author : Christopher B. Hergott
Publisher :
ISBN 13 :
Total Pages : 448 pages
Book Rating : 4.:/5 (945 download)
Download or read book Microbial Manipulation of Phagocyte Function During Infection and Health written by Christopher B. Hergott and published by . This book was released on 2015 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phagocytic cells comprise a central component of the inflammatory response to pathogens, particularly against extracellular bacteria that proliferate on mucosal surfaces. Mounting evidence suggests that microbes can manipulate phagocyte function dynamically to shape the persistence and efficacy of antibacterial defenses. Successful pathogens often restrain inflammatory responses to evade clearance and promote dissemination within the host. In contrast, commensal bacterial communities have been shown to bolster the functional capacity of phagocytes throughout the body. Despite the critical role of microbe-phagocyte interactions in maintaining health and dictating infection outcome, the mechanisms underlying this influence remain incompletely understood. Here, we examined the impact of pathogenic and commensal microbes on the functions of neutrophils, monocytes, and macrophages, three phagocyte subsets indispensable for antibacterial host defense. Using a mouse model of upper airway infection, we found that the bacterial pathogen Streptococcus pneumoniae (the pneumococcus) exploits molecular mimicry to disarm responding neutrophils. Phosphorylcholine (ChoP) moieties displayed on the exterior of the pneumococcus and within the inflammatory phospholipid platelet-activating factor (PAF) allow the microbe to leverage its ChoP-remodeling enzyme, Pce, to remove PAF from the airway. Neutrophils deprived of PAF signaling fail to eliminate bacteria effectively, allowing the pneumococcus to persist, disseminate systemically, and transmit efficiently between hosts. We found that the pneumococcus also manipulates mononuclear phagocyte responses by stimulating the liberation of macrophage migration inhibitory factor (MIF), a cytokine responsible for retaining macrophages at sites of inflammation. MIF-driven macrophage responses accelerate pneumococcal clearance from the upper airway. However, MIF signaling provokes damaging inflammation and impairs bacterial control during pneumococcal pneumonia, underscoring the tight regulation of phagocyte responses required for effective host defense. Finally, we studied the impact of signals from the intestinal microbiota on systemic phagocyte lifespan, a key component of cellular fitness at homeostasis. We found that a neomycin-sensitive cohort of commensal bacteria augments the survival and circulating lifespan of neutrophils and inflammatory monocytes. This stimulation required signaling through the intracellular peptidoglycan sensor Nod1 and liberation of the pro-inflammatory cytokine IL-17A. Together, these data demonstrate that bacteria modulate phagocyte physiology during infection and health, influencing host readiness and response to pathogenic threats.
Author : R. van Furth
Publisher : Springer Science & Business Media
ISBN 13 : 9400987935
Total Pages : 1949 pages
Book Rating : 4.4/5 (9 download)
Download or read book Mononuclear Phagocytes written by R. van Furth and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 1949 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ko Ko Gyi
Publisher :
ISBN 13 :
Total Pages : 108 pages
Book Rating : 4.:/5 (852 download)
Download or read book Effect of Various Agents on Phagocyte Function written by Ko Ko Gyi and published by . This book was released on 1954 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Frans P. Nijkamp
Publisher : Springer Science & Business Media
ISBN 13 : 3034601352
Total Pages : 743 pages
Book Rating : 4.0/5 (346 download)
Download or read book Principles of Immunopharmacology written by Frans P. Nijkamp and published by Springer Science & Business Media. This book was released on 2011-09-01 with total page 743 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a unique support in gaining essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The first section of the book, covering a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts. The second section on immunodiagnostics has been further expanded to describe widely used molecular techniques and is followed by a systematic coverage of drugs affecting the immune system, revised to cover recent developments. The book concludes with a chapter on immunotoxicology. This third edition continues the unique format dealing with four related topics in a single volume, obviating the need to refer to several different textbooks. New aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first edition.
Author : Kathleen E. Sullivan
Publisher : Academic Press
ISBN 13 : 0128172959
Total Pages : 1334 pages
Book Rating : 4.1/5 (281 download)
Download or read book Stiehm's Immune Deficiencies written by Kathleen E. Sullivan and published by Academic Press. This book was released on 2020-05-23 with total page 1334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stiehm’s Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy. Covers immune deficiencies that are presented in a practical way, providing helpful information for active clinicians Fills an increasingly deep gap in the information available to clinicians Presents both clinical management and scientific advances for immune deficiencies Provides a primary resource for physicians in the field of immunodeficiencies Includes website access to a range of videos relevant to the topics discussed
Author : Terence John Lenehan
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (81 download)
Download or read book Mechanisms of Phagocyte Function written by Terence John Lenehan and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
