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Phage Origins Molecular Biology
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Book Synopsis Phage and the Origins of Molecular Biology by : John Cairns
Download or read book Phage and the Origins of Molecular Biology written by John Cairns and published by CSHL Press. This book was released on 2007 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1966 as a 60th birthday tribute to Max Delbrck, this influential work is republished as "The Centennial Edition." The book was hailed as "[introducing] into the literature of science, for the first time, a self-conscious historical element in which the participants in scientific discovery engage in writing their own chronicle ("Journal of History of Biology").
Book Synopsis Phage Origins Molecular Biology by : CARINS
Download or read book Phage Origins Molecular Biology written by CARINS and published by . This book was released on 2018-07-31 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Félix d`Herelle and the Origins of Molecular Biology by : William C. Summers
Download or read book Félix d`Herelle and the Origins of Molecular Biology written by William C. Summers and published by Yale University Press. This book was released on 1999-06-10 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: A self-taught scientist determined to bring science out of the laboratory and into the practical arena, French-Canadian Felix d’Herelle (1873-1949) made history in two different fields of biology. Not only was he first to demonstrate the use and application of bacteria for biological control of insect pests, he also became a seminal figure in the history of molecular biology. This engaging book is the first full biography of d’Herelle, a complex figure who emulated Louis Pasteur and influenced the course of twentieth-century biology, yet remained a controversial outsider to the scientific community. Drawing on family papers, archival sources, interviews, and d’Herelle’s published and unpublished writings, Dr. William C. Summers tells the fascinating story of the scientist’s life and the work that took him around the globe. In 1917, d’Herelle published the first paper describing the phenomenon of the bacteriophage and its biological nature. A series of more than 110 articles and 6 major books followed, in which d’Herelle established the foundation for the later work of the Phage Group in molecular biology. Yet d’Herelle sometimes inspired animosity in others--he was drummed out of the Pasteur Institute, he held only one brief permanent position in the scientific establishment (at Yale University from 1928 to 1933), and he was bewildered by the social nuances of the world of international science. His story is more than the biography of a single brilliant scientist; it is also a fascinating chapter in the history of biology.
Book Synopsis A History of Molecular Biology by : Michel Morange
Download or read book A History of Molecular Biology written by Michel Morange and published by Harvard University Press. This book was released on 2000 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of science, Morange describes the major discoveries--the double helix, messenger RNA, oncogenes, DNA polymerase--but also explains how and why these breakthroughs took place. The book is enlivened by mini-biographies of the founders of molecular biology: Delbrück, Watson and Crick, Monod and Jacob, Nirenberg. This ambitious history covers the story of the transformation of biology over the last one hundred years; the transformation of disciplines: biochemistry, genetics, embryology, and evolutionary biology; and, finally, the emergence of the biotechnology industry. An important contribution to the history of science, A History of Molecular Biology will also be valued by general readers for its clear explanations of the theory and practice of molecular biology today. Molecular biologists themselves will find Morange's historical perspective critical to an understanding of what is at stake in current biological research.
Book Synopsis The American Phage Group by : William C. Summers
Download or read book The American Phage Group written by William C. Summers and published by Yale University Press. This book was released on 2023-01-10 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fascinating historical account of the American Phage Group and how its new research framework became the foundation for molecular biology This book is the first critical and analytical study of the American Phage Group—a small group of scientists who gathered around Max Delbrück, Salvador Luria, and Alfred Hershey between 1940 and 1960—and how this novel research program became the foundation of the field of molecular biology. These three young, charismatic, and iconoclastic scientists were convinced of the importance of bacterial viruses (bacteriophages) to the study of the gene and of heredity in general. Based on substantial archival research, numerous participant interviews collected over the past thirty years, and an intimate knowledge of the relevant scientific literature in the field, William C. Summers has written a fascinating new history of the American Phage Group. Rather than a linear narrative of progress by past heroes, this book emphasizes the diversity and historical contingencies in the group’s development.
Book Synopsis We Can Sleep Later by : Alfred Day Hershey
Download or read book We Can Sleep Later written by Alfred Day Hershey and published by CSHL Press. This book was released on 2000 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: An absorbing portrait of the pioneering molecular biologist best known for demonstrating that DNA is the genetic component of phages, through essays and reminiscences from twenty–three distinguished scientists whose work and careers were influenced by the man and his science.
Download or read book Phage Display written by Carlos F. Barbas and published by CSHL Press. This book was released on 2001 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phage-display technology has begun to make critical contributions to the study of molecular recognition. DNA sequences are cloned into phage, which then present on their surface the proteins encoded by the DNA. Individual phage are rescued through interaction of the displayed protein with a ligand, and the specific phage is amplified by infection of bacteria. Phage-display technology is powerful but challenging and the aim of this manual is to provide comprehensive instruction in its theoretical and applied so that any scientist with even modest molecular biology experience can effectively employ it. The manual reflects nearly a decade of experience with students of greatly varying technical expertise andexperience who attended a course on the technology at Cold Spring Harbor Laboratory. Phage-display technology is growing in importance and power. This manual is an unrivalled source of expertise in its execution and application.
Book Synopsis The Black Box of Biology by : Michel Morange
Download or read book The Black Box of Biology written by Michel Morange and published by Harvard University Press. This book was released on 2020-06-09 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.
Download or read book A Genetic Switch written by Mark Ptashne and published by CSHL Press. This book was released on 2004 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of Mark Ptashne's 1986 book describing the principles of gene regulation in phage lambda became a classic in both content and form, setting a standard of clarity and precise prose that has rarely been bettered. This newly updated third edition focuses once again solely on phage, incorporating the most recent insights into gene expression in prokaryotes while retaining all the special qualities of the original edition
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Single-stranded RNA phages by : Paul Pumpens
Download or read book Single-stranded RNA phages written by Paul Pumpens and published by CRC Press. This book was released on 2020-02-03 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first discovered in 1961. These phages played a unique role in early studies of molecular biology, the genetic code, translation, replication, suppression of mutations. Special attention is devoted to modern applications of the RNA phages and their products in nanotechnology, vaccinology, gene discovery, evolutionary and environmental studies. Included is an overview of the generation of novel vaccines, gene therapy vectors, drug delivery, and diagnostic tools exploring the role of RNA phage-derived products in the revolutionary progress of the protein tethering and bioimaging protocols. Key Features Presents the first full guide to single-stranded RNA phages Reviews the history of molecular biology summarizing the role RNA phages in the development of the life sciences Demonstrates how RNA phage-derived products have resulted in nanotechnological applications Presents an up-to-date account of the role played by RNA phages in evolutionary and environmental studies
Book Synopsis The Forgotten Cure by : Anna Kuchment
Download or read book The Forgotten Cure written by Anna Kuchment and published by Springer Science & Business Media. This book was released on 2011-12-09 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book fills a void. Never before has a comprehensive history of phage therapy—a once-neglected, now resurgent field—been written. Kuchment writes from the perspective of the eager student of history for the common reader.
Book Synopsis Landmark Experiments in Molecular Biology by : Michael Fry
Download or read book Landmark Experiments in Molecular Biology written by Michael Fry and published by Academic Press. This book was released on 2016-06-10 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. Includes detailed analysis of classically designed and executed experiments Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries Provides critical analysis of the history of molecular biology to inform the future of scientific discovery Examines the machinery of inheritance and biological information handling
Book Synopsis Molecular Biology of Bacterial Viruses by : Gunther Siegmund Stent
Download or read book Molecular Biology of Bacterial Viruses written by Gunther Siegmund Stent and published by . This book was released on 1963 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Molecular Biology of Bacterial Virus Systems by : G. Hobom
Download or read book The Molecular Biology of Bacterial Virus Systems written by G. Hobom and published by . This book was released on 2014-01-15 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Perfect Predator by : Steffanie Strathdee
Download or read book The Perfect Predator written by Steffanie Strathdee and published by Hachette Books. This book was released on 2019-02-26 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: An electrifying memoir of one woman's extraordinary effort to save her husband's life-and the discovery of a forgotten cure that has the potential to save millions more. "A memoir that reads like a thriller." -New York Times Book Review "A fascinating and terrifying peek into the devastating outcomes of antibiotic misuse-and what happens when standard health care falls short." -Scientific American Epidemiologist Steffanie Strathdee and her husband, psychologist Tom Patterson, were vacationing in Egypt when Tom came down with a stomach bug. What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world. Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure. A nail-biting medical mystery, The Perfect Predator is a story of love and survival against all odds, and the (re)discovery of a powerful new weapon in the global superbug crisis.
Download or read book Bacteriophage written by Stephen Mc Grath and published by . This book was released on 2007 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt:
