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Perspectives Devolution Des Essais Cliniques En 2021
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Book Synopsis Perspectives d'évolution des essais cliniques en 2021 by : Louise Bossis
Download or read book Perspectives d'évolution des essais cliniques en 2021 written by Louise Bossis and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Actuellement au sein de l'industrie pharmaceutique, le recrutement des patients pour les essais cliniques est devenu un véritable challenge. De nombreux essais cliniques n'atteignent pas leurs objectifs de recrutement, ce qui conduit à des retards, l'impossibilité de fournir des résultats par manque de puissance statistique, ou encore à un arrêt de l'essai avant la date de fin prévue initialement. Les promoteurs d'essais cliniques réfléchissent à comment faire évoluer les essais cliniques en travaillant notamment sur la conception des protocoles, le choix des centres investigateurs et l'identification en amont des patients pour faire face à ce défi. L'ère du numérique dans laquelle nous vivons actuellement est génératrice de changements. Ces changements permettent d'améliorer certains processus. De nouvelles solutions ont été imaginées et continuent de se développer avec l'utilisation de technologies digitales ainsi que l'utilisation croissante de bases de données électroniques de santé. Afin de diminuer le temps et les coûts de développement, les industries pharmaceutiques s'adaptent pour accélérer le développement des médicaments et leur mise sur le marché.
Book Synopsis Cerebral Small Vessel Disease by : Leonardo Pantoni
Download or read book Cerebral Small Vessel Disease written by Leonardo Pantoni and published by Cambridge University Press. This book was released on 2014-05 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.
Book Synopsis Onconephrology by : Kenar D. Jhaveri
Download or read book Onconephrology written by Kenar D. Jhaveri and published by Springer. This book was released on 2015-08-07 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This case based resource focuses on kidney disease in patients with cancer. Chapters cover the pathophysiology and management of specific kidney diseases in cancer patients, as well as the impact of chemotherapy, toxicity of organ and stem cell transplantation and other emerging therapies. Filling a significant knowledge gap in this burgeoning field, Onconephrology features the latest evidence and clinical approaches for the beginner or experienced practitioner.
Book Synopsis Handbook of Data Science Approaches for Biomedical Engineering by : Valentina Emilia Balas
Download or read book Handbook of Data Science Approaches for Biomedical Engineering written by Valentina Emilia Balas and published by Academic Press. This book was released on 2019-11-13 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Data Science Approaches for Biomedical Engineering covers the research issues and concepts of biomedical engineering progress and the ways they are aligning with the latest technologies in IoT and big data. In addition, the book includes various real-time/offline medical applications that directly or indirectly rely on medical and information technology. Case studies in the field of medical science, i.e., biomedical engineering, computer science, information security, and interdisciplinary tools, along with modern tools and the technologies used are also included to enhance understanding. Today, the role of Big Data and IoT proves that ninety percent of data currently available has been generated in the last couple of years, with rapid increases happening every day. The reason for this growth is increasing in communication through electronic devices, sensors, web logs, global positioning system (GPS) data, mobile data, IoT, etc. Provides in-depth information about Biomedical Engineering with Big Data and Internet of Things Includes technical approaches for solving real-time healthcare problems and practical solutions through case studies in Big Data and Internet of Things Discusses big data applications for healthcare management, such as predictive analytics and forecasting, big data integration for medical data, algorithms and techniques to speed up the analysis of big medical data, and more
Book Synopsis Microbe Hunters, Then and Now by : Hilary Koprowski
Download or read book Microbe Hunters, Then and Now written by Hilary Koprowski and published by . This book was released on 1996 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Built upon the foundation of Paul de Kruif's Microbe Hunters, written in 1926, but differing in that the conquest unfolds through essays by today's scientists, this book not only relates the history, but also conveys the excitement felt by the individual researchers themselves. These dramatic stories, describing major accomplishments and future challenges in medical science, serve as a beacon to guide new recruits into the battle for control of microbial diseases and provide personal models for graduate and postdoctoral students currently in biomedical research. "There are some fine ingredients here, and it is good to have them together in a single volume embracing past achievements and current and emerging problems in the control of infectious diseases." Especially enjoyed Thomas Weller's account, complete with pages of laboratory notebook, of his isolation of the agent(s) of varicella and zoster. Bernard Dixon, British Medical Journal. "The authors, all distinguished and well-known scientists, recognize the difficult challenges that lie ahead, but in general hold an optimistic view of the outcome of future research." Microbe Hunters then and now is both interesting and enjoyable to read, a timely sequel to de Kruif's original book and a solid historical document written by the microbe hunters themselves. Abner L. Notkins, Nature Medicine. To order, call: (800) 500-8205 or write: MEDI-ED Press, #5 White Place, Bloomington, IL 61701.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309388708 Total Pages :201 pages Book Rating :4.3/5 (93 download)
Book Synopsis Mitochondrial Replacement Techniques by : National Academies of Sciences, Engineering, and Medicine
Download or read book Mitochondrial Replacement Techniques written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-04-17 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the technique raises significant ethical and social issues. It would create offspring who have genetic material from two women, something never sanctioned in humans, and would create mitochondrial changes that could be heritable (in female offspring), and therefore passed on in perpetuity. The manipulation would be performed on eggs or embryos, would affect every cell of the resulting individual, and once carried out this genetic manipulation is not reversible. Mitochondrial Replacement Techniques considers the implications of manipulating mitochondrial content both in children born to women as a result of participating in these studies and in descendants of any female offspring. This study examines the ethical and social issues related to MRTs, outlines principles that would provide a framework and foundation for oversight of MRTs, and develops recommendations to inform the Food and Drug Administration's consideration of investigational new drug applications.
Download or read book Hepatitis B written by Baruch S. Blumberg and published by Princeton University Press. This book was released on 2002 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: About 375 million people are infected with the hepatitis B virus. It has killed more people than AIDS and also causes millions of cases of liver cancer. The discovery of this deadly virus and the vaccine against it--a vaccine that is sharply decreasing the infection rate worldwide and is probably the first effective cancer vaccine--was one of the great triumphs of twentieth-century medicine. And it almost didn't happen. With wit and insight, this scientific memoir and story of discovery describes how Baruch Blumberg and a team of researchers found a virus they were not looking for and created a vaccine for a disease they previously knew little about--work that took the author around the world and won him the Nobel Prize. Blumberg and his collaborators were investigating relationships between gene distribution and disease susceptibility, research that was yielding interesting data but no real breakthroughs. Many viewed their work as more field trip than science. But, through decades of hard work and investigative twists and turns, their pursuit led to the hepatitis B antigen, the elusive virus itself, and, ultimately, the vaccine. As he takes the reader through the detective work that culminated in his incredible discovery, the author recounts with immediacy exciting moments in the lab and in the field--from a hair-raising flight to Africa to an unpleasant encounter with Alaskan sled dogs. The hepatitis B story is more than a fascinating chronicle of a major discovery. What Blumberg followed to the virus was a trail of remarkable "accidents" that happen when scientists seek answers to interesting questions. Those events, combined with the investigator's determined persistence, resulted in studies that generated a pharmaceutical industry, have far-flung public-health applications, and saved millions of lives.
Book Synopsis Handbook of Inter-Rater Reliability, 4th Edition by : Kilem L. Gwet
Download or read book Handbook of Inter-Rater Reliability, 4th Edition written by Kilem L. Gwet and published by Advanced Analytics, LLC. This book was released on 2014-09-07 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this book was very well received by researchers working in many different fields of research. The use of that text also gave these researchers the opportunity to raise questions, and express additional needs for materials on techniques poorly covered in the literature. For example, when designing an inter-rater reliability study, many researchers wanted to know how to determine the optimal number of raters and the optimal number of subjects that should participate in the experiment. Also, very little space in the literature has been devoted to the notion of intra-rater reliability, particularly for quantitative measurements. The fourth edition of this text addresses those needs, in addition to further refining the presentation of the material already covered in the third edition. Features of the Fourth Edition include: New material on sample size calculations for chance-corrected agreement coefficients, as well as for intraclass correlation coefficients. The researcher will be able to determine the optimal number raters, subjects, and trials per subject.The chapter entitled “Benchmarking Inter-Rater Reliability Coefficients” has been entirely rewritten.The introductory chapter has been substantially expanded to explore possible definitions of the notion of inter-rater reliability.All chapters have been revised to a large extent to improve their readability.
Download or read book Cancer on Trial written by Peter Keating and published by University of Chicago Press. This book was released on 2014-04-18 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: There were no medical oncologists until a few decades ago. In the early 1960s, not only were there no such specialists, many practitioners regarded the treatment of terminally-ill cancer patients with heroic courses of chemotherapy as highly questionable. Physicians loath to assign patients randomly to competing treatments also expressed their outright opposition to the randomized clinical trials that were then relatively rare. And yet today these trials form the basis of medical oncology. How did such a spectacular change occur? How did medical oncology move from a non-entity and in some regards a reviled practice to the central position it now occupies in modern medicine? Cancer on Trial answers these questions by exploring how practitioners established a new style of practice, at the center of which lies the cancer clinical trial.
Book Synopsis Trauma and Resilience Among Displaced Populations by : Gail Theisen-Womersley
Download or read book Trauma and Resilience Among Displaced Populations written by Gail Theisen-Womersley and published by Springer Nature. This book was released on 2021-03-19 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides an enriched understanding of historical, collective, cultural, and identity-related trauma, emphasising the social and political location of human subjects. It therefore presents a socio-ecological perspective on trauma, rather than viewing displaced individuals as traumatised “passive victims”. The vastness of the phenomenon of trauma among displaced populations has led it to become a critical and timely area of inquiry, and this book is an important addition to the literature. It gives an overview of theoretical frameworks related to trauma and migration—exploring factors of risk and resilience, prevalence rates of PTSD, and conceptualisations of trauma beyond psychiatric diagnoses; conceptualises experiences of trauma from a sociocultural perspective (including collective trauma, collective aspirations, and collective resilience); and provides applications for professionals working with displaced populations in complex institutional, legal, and humanitarian settings. It includes case studies based on the author’s own 10-year experience working in emergency contexts with displaced populations in 11 countries across the world. This book presents unique data collected by the author herself, including interviews with survivors of ISIS attacks, with an asylum seeker in Switzerland who set himself alight in protest against asylum procedures, and women from the Murle tribe affected by the conflict in South Sudan who experienced an episode of mass fainting spells. This is an important resource for academics and professionals working in the field of trauma studies and with traumatised groups and individuals.
Book Synopsis Assessing Quality of Life in Clinical Trials by : Peter M. Fayers
Download or read book Assessing Quality of Life in Clinical Trials written by Peter M. Fayers and published by . This book was released on 2005 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers in all clinical fields are fully aware of the importance of Quality of Life measurements in judging the efficacy of a given treatment. Psychological criteria play an important role in this evaluation. Assessment of Quality of Life in Clinical Trials: methods and practice explores the current state of the art and illustrates the benefits and potential of health related quality of life assessment in clinical trials. It covers a wide range of analytical issues, emphasizing new and innovative approaches that are of practical and clinical importance.
Book Synopsis The War Against Hepatitis B by : William A. Muraskin
Download or read book The War Against Hepatitis B written by William A. Muraskin and published by . This book was released on 1995 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The story of a group of scientists who set out to conquer hepatitis B, focusing on the International Task Force's encounters with opposition from economic and political forces. Draws on classified and confidential documents and on interviews with Task Force members, government representatives, and institutional officials to dramatize the turf wars, international politics, and internal tensions the Task Force overcame to lower prices of the vaccine against the disease and make universal immunization a priority. Annotation copyright by Book News, Inc., Portland, OR
Book Synopsis Religion and Spirituality in Psychiatry by : Philippe Huguelet
Download or read book Religion and Spirituality in Psychiatry written by Philippe Huguelet and published by Cambridge University Press. This book was released on 2009-03-30 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was the first to specifically address the impact of religion and spirituality on mental illness.
Author :Parkinson's Disease Information and Research Center (New York, N.Y.) Publisher : ISBN 13 : Total Pages :452 pages Book Rating :4.3/5 (91 download)
Book Synopsis Parkinson's Disease & Related Disorders; Cumulative Bibliography: 1800-1970: Author index by : Parkinson's Disease Information and Research Center (New York, N.Y.)
Download or read book Parkinson's Disease & Related Disorders; Cumulative Bibliography: 1800-1970: Author index written by Parkinson's Disease Information and Research Center (New York, N.Y.) and published by . This book was released on 1971 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Androgen Deprivation Therapy by : Richard J. Wassersug, PhD
Download or read book Androgen Deprivation Therapy written by Richard J. Wassersug, PhD and published by Springer Publishing Company. This book was released on 2021-07-12 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for Androgen Deprivation Therapy: "To my knowledge [this] is the only book written in plain language (no medical jargon) explaining what’s happening during ADT, and detailing how to limit and often solve most associated side effects. It should be read by every man undergoing ADT, as well as family members and also healthcare providers. They will find all the details they need to get the most from this treatment..." Prof. N. Mottet, MD, PhD, Urologist, Medical Oncologist, Head of the Prostate Cancer Guidelines panel of the European Association of Urology Androgen Deprivation Therapy is the only guide written exclusively about the side effects of hormone therapy. The authors have collaborated with the European Association of Urology to produce this specially revised new edition to serve men affected by ADT across the globe. This comprehensive workbook for prostate cancer patients and their loved ones is filled with practical advice from experts in the field. The book covers a wealth of strategies to help men cope with ADT and maintain a good quality of life while on this treatment. It is not only an informational manual, but a guide for both patients and partners about ways to make changes in their lives that can keep them healthy and positive when the patient is on ADT. New to this Edition: Updates on the physical side effects of ADT and management strategies Expanded information on exercise and nutrition for men diagnosed with prostate cancer Updates on the primary drugs used to treat prostate cancer and extensive drug tables with common brand names worldwide Revisions throughout based on critical feedback from international medical experts in the field of prostate cancer and related disciplines Exercises, activities, worksheets, and other tools to promote discussion and inspire behavioural changes that can reduce the burden of ADT Officially endorsed by the European Association of Urology
Book Synopsis GDPR and Biobanking by : Jane Reichel
Download or read book GDPR and Biobanking written by Jane Reichel and published by Springer Nature. This book was released on 2021 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part I Setting the scene -- Introduction: Individual rights, the public interest and biobank research 4000 (8) -- Genetic data and privacy protection -- Part II GDPR and European responses -- Biobank governance and the impact of the GDPR on the regulation of biobank research -- Controller' and processor's responsibilities in biobank research under GDPR -- Individual rights in biobank research under GDPR -- Safeguards and derogations relating to processing for archiving purposes in the scientific purposes: Article 89 analysis for biobank research -- A Pan-European analysis of Article 89 implementation and national biobank research regulations -- EEA, Switzerland analysis of GDPR requirements and national biobank research regulations -- Part III National insights in biobank regulatory frameworks -- Selected 10-15 countries for reports: Germany -- Greece -- France -- Finland -- Sweden -- United Kingdom -- Part IV Conclusions -- Reflections on individual rights, the public interest and biobank research, ramifications and ways forward. .
Author :United States. National Institute of Neurologiacal Diseases and Stroke Publisher : ISBN 13 : Total Pages :462 pages Book Rating :4.F/5 ( download)
Book Synopsis Parkinson's Disease and Related Disorders by : United States. National Institute of Neurologiacal Diseases and Stroke
Download or read book Parkinson's Disease and Related Disorders written by United States. National Institute of Neurologiacal Diseases and Stroke and published by . This book was released on 1971 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt:
