Personalized Immunosuppression In Transplantation

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Personalized Immunosuppression in Transplantation

Author : Michael Oellerich
Publisher : Elsevier
ISBN 13 : 0128011335
Total Pages : 316 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Personalized Immunosuppression in Transplantation by : Michael Oellerich

Download or read book Personalized Immunosuppression in Transplantation written by Michael Oellerich and published by Elsevier. This book was released on 2015-08-08 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring provides coverage of the various approaches to monitoring immunosuppressants in transplant patients, including the most recently developed biomarker monitoring methods, pharmacogenomics approaches, and traditional therapeutic drug monitoring. The book is written for pathologists, toxicologists, and transplant surgeons who are involved in the management of transplant patients, offering them in-depth coverage of the management of immunosuppressant therapy in transplant patients with the goal of maximum benefit from drug therapy and minimal risk of drug toxicity. This book also provides practical guidelines for managing immunosuppressant therapy, including the therapeutic ranges of various immunosuppressants, the pitfalls of methodologies used for determination of these immunosuppressants in whole blood or plasma, appropriate pharmacogenomics testing for organ transplant recipients, and when biomarker monitoring could be helpful. Focuses on the personalized management of immunosuppression therapy in individual transplant patients Presents information that applies to many areas, including gmass spectrometry, assay design, assay validation, clinical chemistry, and clinical pathology Provides practical guidelines for the initial selection and subsequent modifications of immunosuppression therapy in individual transplant patients Reviews the latest research in biomarker monitoring in personalizing immunosuppressant therapy, including potential new markers not currently used, but with great potential for future use Explains how monitoring graft-derived, circulating, cell free DNA has shown promise in the early detection of transplant injury in liquid biopsy

Organ Donation and Transplantation

Author : Georgios Tsoulfas
Publisher : BoD – Books on Demand
ISBN 13 : 1789233402
Total Pages : 454 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Organ Donation and Transplantation by : Georgios Tsoulfas

Download or read book Organ Donation and Transplantation written by Georgios Tsoulfas and published by BoD – Books on Demand. This book was released on 2018-07-25 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most interesting and at the same time most challenging fields of medicine and surgery has been that of organ donation and transplantation. It is a field that has made tremendous strides during the last few decades through the combined input and efforts of scientists from various specialties. What started as a dream of pioneers has become a reality for the thousands of our patients whose lives can now be saved and improved. However, at the same time, the challenges remain significant and so do the expectations. This book will be a collection of chapters describing these same challenges involved including the ethical, legal, and medical issues in organ donation and the technical and immunological problems the experts are facing involved in the care of these patients.The authors of this book represent a team of true global experts on the topic. In addition to the knowledge shared, the authors provide their personal clinical experience on a variety of different aspects of organ donation and transplantation.

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

Author : Gerard Socie
Publisher : Academic Press
ISBN 13 : 0128134399
Total Pages : 430 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation by : Gerard Socie

Download or read book Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation written by Gerard Socie and published by Academic Press. This book was released on 2018-11-22 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications

Kidney Transplant Management

Author : Sandesh Parajuli
Publisher : Springer
ISBN 13 : 3030001326
Total Pages : 201 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Kidney Transplant Management by : Sandesh Parajuli

Download or read book Kidney Transplant Management written by Sandesh Parajuli and published by Springer. This book was released on 2018-10-30 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise book provides an overview of the essential aspects of transplant nephrology. Chapters cover patient evaluation, treatment options, complications and post kidney transplant approaches to various common chronic diseases. The importance of proper immunosuppressants adjustment to improve the graft half-life and overall patient quality of life are also highlighted. Up to date and practical, this book gives nephrologists and providers that treat kidney transplant patients a succinct resource on management.

Handbook of Kidney Transplantation

Author : Gabriel M. Danovitch
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451148305
Total Pages : 496 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Handbook of Kidney Transplantation by : Gabriel M. Danovitch

Download or read book Handbook of Kidney Transplantation written by Gabriel M. Danovitch and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: This popular handbook is a practical guide for physicians, surgeons, nurses, and other professionals who manage kidney transplant patients. It is concise, readable, and well-illustrated. Chapters outline the major concerns surrounding renal transplantation and the most successful approaches to problems arising in short-term and long-term patient care. Chapter topics include immunobiology and immunosuppression, as well as chapters on surgery, histocompatibility, and the first three months post-transplant surgery. This thoroughly updated Fifth Edition includes new information on options for patients with end-stage renal disease, immunosuppressive medications and protocols for kidney transplantation, and the first two months following transplant.

Combined Liver-kidney Transplantation

Author : Martin Erlichman
Publisher :
ISBN 13 :
Total Pages : 12 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Combined Liver-kidney Transplantation by : Martin Erlichman

Download or read book Combined Liver-kidney Transplantation written by Martin Erlichman and published by . This book was released on 1995 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pediatric Renal Transplantation

Author : Amir H. Tejani
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 576 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pediatric Renal Transplantation by : Amir H. Tejani

Download or read book Pediatric Renal Transplantation written by Amir H. Tejani and published by Wiley-Liss. This book was released on 1994-08-16 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: A detailed, contributed reference offering broad coverage of renal transplantation in children. Diagnosis, the patient's medical management, operative methods, surgical and medical complications, donor selection, immunosuppression, late effects on growth and development and psychosocial factors are among the topics discussed. Features a chapter on how to set up and manage a pediatric renal transplant program.

Transplantation of Marginal Organs: Immunological Aspects and Therapeutic Perspectives

Author : Caner Süsal
Publisher : Frontiers Media SA
ISBN 13 : 288966287X
Total Pages : 183 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Transplantation of Marginal Organs: Immunological Aspects and Therapeutic Perspectives by : Caner Süsal

Download or read book Transplantation of Marginal Organs: Immunological Aspects and Therapeutic Perspectives written by Caner Süsal and published by Frontiers Media SA. This book was released on 2020-12-28 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Emerging Transplant Infections

Author : Michele I. Morris
Publisher : Springer
ISBN 13 : 9783030258689
Total Pages : 0 pages
Book Rating : 4.2/5 (586 download)

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Book Synopsis Emerging Transplant Infections by : Michele I. Morris

Download or read book Emerging Transplant Infections written by Michele I. Morris and published by Springer. This book was released on 2021-06-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of transplant medicine has evolved significantly since the first kidney transplant was performed in 1954. Innovations in transplant immunosuppression have lowered the risk of organ rejection so that infectious complications are now the leading cause of hospitalization and mortality after solid organ transplant. Infection is also cited as the leading cause of non-relapse mortality after stem cell transplantation. As transplant centers have recognized the importance of transplant specific expertise in patient outcomes, the field of transplant infectious diseases has expanded into a recognized and highly valued subspecialty. International growth in solid organ and stem cell transplantation has outpaced access to such expertise, with some centers employing microbiology laboratory directors and transplant nephrologists as their lead infectious diseases consultants. This has been a particular challenge as the use of novel immunosuppressive regimens in new geographic and immigrant populations have fueled the emergence of new infection syndromes, with the initial presentation sometimes occurring in this most vulnerable patient population. This digital-first book is designed to meet the needs of practitioners engaged in transplant infectious disease practice who need more depth than they are able to find in UpToDate. It provides an overview of emerging infectious disease challenges with clinically relevant information regarding the epidemiology, diagnosis, management, and prevention of infections in solid organ and stem cell transplant recipients. Each chapter focuses on a clinical syndrome or pathogen with new or emerging implications for transplant patients. Given the rapidly evolving nature of emerging infections and topics in transplant infections, no resource has been published on these increasingly notorious issues; this this text is written by top, global experts who regularly update the material to ensure that readers will always have access to the most cutting edge material available. The editorial team consists of three experienced leaders in the field, all of whom have a strong record of scholarship and publication, as well as an international reputation. All three have focused their academic careers on emerging infectious diseases in transplantation, including a current and a past president of various infectious diseases and transplantation societies. The editors are also experienced reviewers and authors who have collaborated on multiple previous projects. All are committed to this project as a unique opportunity to make an important contribution to their field.

Dermatology and Solid Organ Transplantation

Author : Nathalie C. Zeitouni
Publisher : CRC Press
ISBN 13 : 1000415929
Total Pages : 395 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Dermatology and Solid Organ Transplantation by : Nathalie C. Zeitouni

Download or read book Dermatology and Solid Organ Transplantation written by Nathalie C. Zeitouni and published by CRC Press. This book was released on 2021-08-15 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook brings together experts in the field of transplant dermatology to review both state of the art and practical knowledge regarding the clinical presentation and management of the various cutaneous diseases seen in patients with solid organ transplant. Practicing dermatologists, trainees, and other health care providers involved in the care of transplant patients can learn the current diagnostic and management options, and how to apply these guidelines and principles in their everyday practice.

CURRENT Diagnosis and Treatment Surgery: Thirteenth Edition

Author : Gerard Doherty
Publisher : McGraw Hill Professional
ISBN 13 : 0071635157
Total Pages : 1328 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis CURRENT Diagnosis and Treatment Surgery: Thirteenth Edition by : Gerard Doherty

Download or read book CURRENT Diagnosis and Treatment Surgery: Thirteenth Edition written by Gerard Doherty and published by McGraw Hill Professional. This book was released on 2009-08-20 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt: To-the-point information on more than 1000 diseases and disorders surgeons are most likely to encounter The leading single-source surgery book for house-staff, students, practitioners, and surgeons A Doody's Core Title for 2011! "This is an excellent source of updated, authoritative, and concise information on diseases encountered in general surgery and the surgical subspecialties of otolaryngology, urology, gynecology, orthopedics, plastic and reconstructive surgery, and pediatrics....This is a wonderful resource for all levels of surgical practitioners as well as nonsurgical practitioners. In my experience, it has provided me with a framework to prepare for both oral and written boards. 3 Stars."--Doody's Review Service Authoritative, concise, and completely up-to-date, CURRENT Diagnosis & Treatment Surgery features: Wide-ranging coverage that encompasses general surgery and all the important subspecialties including otolaryngology, urology, gynecology, orthopedics, plastic and reconstructive surgery, and pediatrics References linked to recent journal articles Logical quick-find organization made even more accessible by a comprehensive index More than 600 informative photographs and illustrations Detailed treatment algorithms NEW CD-ROM with content from Quick Answers: Surgery to speed diagnosis of symptoms and signs NEW Chapter on Training, Communication, Professionalism, and Systems-Based Practice Completely rewritten chapters on Wound Healing, Anesthesia, Otolaryngology/Head & Neck Surgery, The Heart, Neurosurgery, Gynecology, and Orthopedics

Clinical Guide to Heart Transplantation

Author : Jon Kobashigawa
Publisher : Springer
ISBN 13 : 3319437739
Total Pages : 258 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Clinical Guide to Heart Transplantation by : Jon Kobashigawa

Download or read book Clinical Guide to Heart Transplantation written by Jon Kobashigawa and published by Springer. This book was released on 2017-03-29 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise review of up-to-date concepts and techniques in the discipline of heart transplantation. It is a review and reference for practitioners managing patients with advanced heart disease, including patients with end-stage heart failure, mechanical circulatory support or transplant recipients. Heart failure is a major public health issue, with a prevalence of over 5.8 million in the USA, and over 23 million worldwide, and rising. The lifetime risk of developing heart failure is one in five. Heart failure carries substantial morbidity and mortality, with 5-year mortality that rival those of many cancers. As heart transplantation remains the best treatment option for patients with end stage heart failure, this primer will provide valuable information and management strategies for physicians caring for these patients. Also, due to continued shortage in donor organs, heart transplantation is a limited resource – which further underscores the importance of appropriately evaluating patients for transplant candidacy and managing their pre, peri- and post-transplant care for maximum benefit and best outcomes.

Hepatobiliary Surgery

Author : Ronald S. Chamberlain
Publisher : CRC Press
ISBN 13 : 1498712940
Total Pages : 286 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Hepatobiliary Surgery by : Ronald S. Chamberlain

Download or read book Hepatobiliary Surgery written by Ronald S. Chamberlain and published by CRC Press. This book was released on 2003-01-01 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is written as a reference and guidebook for practicing surgeons, gastroenterologists, and interventional radiologists with an interest in hepatobiliary diseases. It presents a strategy to enhance surgeons practice and the care of patients.

Frontiers in Transplantology

Author : Hesham Abdeldayem
Publisher : BoD – Books on Demand
ISBN 13 : 9535125230
Total Pages : 312 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Frontiers in Transplantology by : Hesham Abdeldayem

Download or read book Frontiers in Transplantology written by Hesham Abdeldayem and published by BoD – Books on Demand. This book was released on 2016-09-07 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is addressed to researchers, practicing physicians, and surgeons in the field of organ transplantation, as well as the medical students, residents, and fellows. The topics covered include the religious concepts in organ transplantation, embryonic organ transplantation, tolerance, normothermic graft perfusion, pharmacogenetics of immunosuppressors, viral transmission in organ transplantation, pediatric and split-liver transplantation, portopulmonary hypertension, mechanical circulatory support, ex vivo lung perfusion, and ABO-incompatible kidney transplantation.

Contemporary Small Bowel Transplantation

Author : Ashesh Piyush Shah
Publisher :
ISBN 13 : 9783319055473
Total Pages : pages
Book Rating : 4.0/5 (554 download)

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Book Synopsis Contemporary Small Bowel Transplantation by : Ashesh Piyush Shah

Download or read book Contemporary Small Bowel Transplantation written by Ashesh Piyush Shah and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Intestinal transplantation remains on the cutting edge of solid organ transplantation. Each potential recipient provides a unique case of intestinal failure with individual intricacies requiring the combined efforts of a complex multidisciplinary team in order to achieve success. Contemporary Small Bowel Transplantation covers all aspects of intestinal transplantation in a manner accessible to all providers and provides specific guidance for those that may come in contact with this field and these patients. The text provides an understanding of the critical pre-operative evaluation, thorough descriptions of each surgical procedure and postoperative management. Areas such as infectious disease, nutrition and graft versus host disease will be addressed in detail. Key controversies and administrative issues unique to intestinal transplantation are covered. Contemporary Small Bowel Transplantation provides critical guidance for the new transplant surgeon, gastroenterologist or administrator as they navigate the challenging field of intestinal transplantation."--Publisher's website.

Xenotransplantation

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309175267
Total Pages : 134 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Xenotransplantation by : Institute of Medicine

Download or read book Xenotransplantation written by Institute of Medicine and published by National Academies Press. This book was released on 1996-07-12 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Xenotransplantation involves the transplantation of cells, tissues, and whole organs from one species to another. Interest in animal-to-human xenotransplants has been spurred by the continuing shortage of donated human organs and by advances in knowledge concerning the biology of organ and tissue rejection. The scientific advances and promise, however, raise complex questions that must be addressed. This book considers the scientific and medical feasibility of xenotransplantation and explores the ethical and public policy issues surrounding the possibility of renewed clinical trials. The volume focuses on the science base of xenotransplantation, public health risks of infectious disease transmission, and ethical and public policy issues, including the views of patients and their families.

Textbook of Personalized Medicine

Author : Kewal K. Jain
Publisher : Springer Nature
ISBN 13 : 3030620808
Total Pages : 744 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Textbook of Personalized Medicine by : Kewal K. Jain

Download or read book Textbook of Personalized Medicine written by Kewal K. Jain and published by Springer Nature. This book was released on 2020-12-05 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is for personalized medicine as a prescription of specific treatments and therapeutics best suited for an individual and considers genetic as well as environmental factors that influence responses to therapy. Best approaches are described for integration of all available technologies for optimizing the therapy of individual patients. This comprehensive third edition covers the latest advances in personalized medicine and several chapters are devoted to various specialties, particulary cancer which is the largest area of application. The book discusses the development of personalized medicine and various players in it such as companies, academic institutions, the government, and the public as the consumer of healthcare. Additionally, the roles of bioinformatics, electronic health records, and digital technologies for personalized medicine are discussed. Textbook of Personalized Medicine, 3rd Edition serves as a convenient source of information for students at many levels and in a wide range of fields, including physicians, scientists, and decision makers in the biopharmaceutical and healthcare industries.