Pathogenesis And Prevention Of Fetal And Neonatal Brain Injury

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Pathogenesis and Prevention of Fetal and Neonatal Brain Injury

Author : Andrew Macnab
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis Pathogenesis and Prevention of Fetal and Neonatal Brain Injury by : Andrew Macnab

Download or read book Pathogenesis and Prevention of Fetal and Neonatal Brain Injury written by Andrew Macnab and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in the clinical management of at-risk pregnancy and care of the newborn have reduced morbidity and mortality among sick neonates, and improved our knowledge of factors that influence the risks of brain injury. In parallel, the refinement of imaging techniques has added to the ability of clinicians to define the etiology, timing and location of pathologic changes with diagnostic and prognostic relevance to the developing fetus and newborn infant. Abnormalities of brain growth, or injury to the developing brain can occur during pregnancy; during labor and delivery, hypoxia, acidosis and ischemia pose major risks to the fetus. Defined practices for the management of pregnancy and delivery, and evidence-based strategies for care in the newborn period are influencing outcome. However, newborn infants, especially those born prematurely, remain at risk from situations that can cause or worsen brain injury. The literature reviewed here explains the mechanisms and timing of injury, and the importance of hypoxia, ischemia, hypotension and infection; describes current diagnostic strategies, neuroimaging technologies and care entities available; and outlines approaches that can be used to prevent or mitigate brain injury. Some show particular promise, and all are relevant to lowering the incidence and severity of brain damage.

Fetal and Neonatal Brain Injury

Author : David K. Stevenson
Publisher : Cambridge University Press
ISBN 13 : 1108506127
Total Pages : 855 pages
Book Rating : 4.1/5 (85 download)

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Book Synopsis Fetal and Neonatal Brain Injury by : David K. Stevenson

Download or read book Fetal and Neonatal Brain Injury written by David K. Stevenson and published by Cambridge University Press. This book was released on 2017-12-21 with total page 855 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improvements in the detection of fetal and neonatal brain injuries, advances in our understanding of the pathophysiology, cellular and molecular bases of encephalopathy, and new treatment options have all combined to produce significant changes in the management of neonatal brain disorders in the past few years. This new edition of Fetal and Neonatal Brain Injury brings the reader fully up to date with all advances in clinical management and outcome assessment. Updated material includes inflammation focusing in particular on chorioamnionitis and fetal brain injury; genetic brain injury; and expanded sections on cholestasis, diabetes, and thyroid disease. An updated, highly illustrated chapter on structural and functional imaging of the fetal and neonatal brain is also included. An outstanding international team of highly experienced neonatologists and maternal-fetal medicine clinicians have produced a practical, authoritative clinical text that gives clear management advice to all clinicians involved in the treatment of these patients.

Fetal and Neonatal Brain Injury

Author : David K. Stevenson
Publisher : Cambridge University Press
ISBN 13 : 9780521806916
Total Pages : 932 pages
Book Rating : 4.8/5 (69 download)

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Book Synopsis Fetal and Neonatal Brain Injury by : David K. Stevenson

Download or read book Fetal and Neonatal Brain Injury written by David K. Stevenson and published by Cambridge University Press. This book was released on 2003-02-06 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition, this is a comprehensive survey of fetal and neonatal brain injury arising from hypoxia, ischemia or other causes. The volume spans a broad range of areas from epidemiology and pathogenesis, through to clinical manifestations and obstetric care, and then on to diagnosis, long-term outcomes, and medico-legal aspects. An important theme running throughout is to highlight scientific and clinical advances that have a role to play in minimising risk, improving clinical care and outcomes.

Perinatal brain damage

Author : Luca Ramenghi
Publisher : John Libbey Eurotext
ISBN 13 : 2742010203
Total Pages : 275 pages
Book Rating : 4.7/5 (42 download)

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Book Synopsis Perinatal brain damage by : Luca Ramenghi

Download or read book Perinatal brain damage written by Luca Ramenghi and published by John Libbey Eurotext. This book was released on 2008-01-01 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is based on a highly successful conference dedicated to “Perinatal brain damage:from pathogenesis to neuroprotection ”. Neonatologists, paediatricians, paediatric neurologists, obstetricians, basic researchers involved in neurosciences, as well as rehabilitation professionals, will be interested by this ensuing publication. The volume covers pathogenic aspects of brain lesions occurring in the fetal and neonatal period, and addresses the issues of diagnostic workup and treatment.The most authoritative basic researchers, clinicians, and specialists in the field of neuroimaging, provide chapters on recent clinical advances. A subject of particular importance is the neurological vulnerability of the preterm infant, which also touches on ethical aspects of the care of high-risk preterm babies and those born from multiple pregnancies. A particularly original session focuses on cerebral white matter and the many issues related to this crucial part of the developing brain. Experts also deal with cerebral visual impairment, motor development, cognitive function, and the mechanisms underlying the neuronal plasticity of the infant’s brain. Concepts of neuroprotection are also outlined, based on pharmacological agents tested on experimental animals and the best drugs used to treat neonatal convulsions.

Neonatal Encephalopathy and Cerebral Palsy

Author : American College of Obstetricians and Gynecologists. Task Force on Neonatal Encephalopathy and Cerebral Palsy
Publisher : American College of Obstetricians and Gynecologists Women's Health Care Physicians
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Neonatal Encephalopathy and Cerebral Palsy by : American College of Obstetricians and Gynecologists. Task Force on Neonatal Encephalopathy and Cerebral Palsy

Download or read book Neonatal Encephalopathy and Cerebral Palsy written by American College of Obstetricians and Gynecologists. Task Force on Neonatal Encephalopathy and Cerebral Palsy and published by American College of Obstetricians and Gynecologists Women's Health Care Physicians. This book was released on 2003 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph explores the mechanisms and timing of possible etiologic events that contribute to fetal and neonatal neurologic injury. the report presents evidence that most cases of cerebral palsy are a result of multifactorial and unpreventable causes that occur during fetal development or in the newborn after delivery, and not a result of an isolated intrapartum hypoxic event. the report contains a set of criteria that may be used to define (or rule out) an acute intrapartum hypoxic event sufficient to cause or suggest cerebral palsy.

Fetal and Neonatal Brain Injury

Author : David Kendal Stevenson
Publisher : Mosby Elsevier Health Science
ISBN 13 :
Total Pages : 304 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Fetal and Neonatal Brain Injury by : David Kendal Stevenson

Download or read book Fetal and Neonatal Brain Injury written by David Kendal Stevenson and published by Mosby Elsevier Health Science. This book was released on 1989 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Progress in Fetal and Neonatal Brain Injury Research

Author : Steven W. Levison
Publisher :
ISBN 13 : 9783805592635
Total Pages : 0 pages
Book Rating : 4.5/5 (926 download)

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Book Synopsis Progress in Fetal and Neonatal Brain Injury Research by : Steven W. Levison

Download or read book Progress in Fetal and Neonatal Brain Injury Research written by Steven W. Levison and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immature brain is vulnerable to prenatal and postnatal stress, which may produce brain damage leading to neurological dysfunction in survivors. The articles in this special issue provide new insights into the pathophysiology and treatment of developmental brain injuries and functional outcomes. Information obtained using preclinical models as well as data from clinical studies emphasize the influence of hypoxia-ischemia, excitotoxicity, oxidative stress, seizures and inflammatory mediators on the outcome of developmental brain injury and ultimate neurological outcome. Importantly, several papers report preclinical tests of new therapies that show real promise in preventing injury to the developing brain including erythropoietin, melatonin and steroids. This publication will be of interest to both clinicians and basic scientists who are interested in the developing nervous system, its vulnerability to various pathophysiological processes and the eventual consequences for neurologic development.

Neonatal Encephalopathy and Neurologic Outcome

Author : American College of Obstetricians and Gy
Publisher : American College of Obstetricians and Gynecologists Women's Health Care Physicians
ISBN 13 : 9781934984307
Total Pages : 0 pages
Book Rating : 4.9/5 (843 download)

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Book Synopsis Neonatal Encephalopathy and Neurologic Outcome by : American College of Obstetricians and Gy

Download or read book Neonatal Encephalopathy and Neurologic Outcome written by American College of Obstetricians and Gy and published by American College of Obstetricians and Gynecologists Women's Health Care Physicians. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significantly revised and updated, the new second edition updates the science on neonatal encephalopathy presented in the 1st edition. The new 2nd edition recommends a broad evaluation of all potential contributing factors in every case of neonatal encephalopathy, including maternal medical history, obstetric and intrapartum factors, and placental pathology. This recommendation is a shift from the 2003 report, which focused on determining whether or not a hypoxic-ischemic event was the cause of neonatal encephalopathy. Includes new sections on - Placental pathology - Focal ischemic stroke - Neonatal interventions - Patient safety - Significant advances in neuroimaging This report will assist the clinician in evaluating a newborn with encephalopathy to assist in defining both the cause and timing.

Fetal and Neonatal Brain Injury

Author : David Kendal Stevenson
Publisher :
ISBN 13 : 9780511580963
Total Pages : 652 pages
Book Rating : 4.5/5 (89 download)

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Book Synopsis Fetal and Neonatal Brain Injury by : David Kendal Stevenson

Download or read book Fetal and Neonatal Brain Injury written by David Kendal Stevenson and published by . This book was released on 2014-05-14 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authoritative, practical clinical text giving clear management advice on diagnosis, treatment and outcomes of all fetal and neonatal brain injuries.

Acquired Brain Injury in the Fetus and Newborn

Author : Michael Shevell
Publisher : Mac Keith Press
ISBN 13 : 9781907655029
Total Pages : 0 pages
Book Rating : 4.6/5 (55 download)

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Book Synopsis Acquired Brain Injury in the Fetus and Newborn by : Michael Shevell

Download or read book Acquired Brain Injury in the Fetus and Newborn written by Michael Shevell and published by Mac Keith Press. This book was released on 2012-12-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Reviews of Child Neurology Series No. 13 Given the tremendous advances in the last five years in the understanding of acquired neonatal brain injury and in the care of affected newborn infants, this book provides a timely review for the practising neurologist, neonatologist and pediatrician. The editors take a pragmatic approach, focusing on specific populations encountered regularly by the clinician. They begin by addressing aspects of fetal neurology and the interpretation of fetal imaging studies. They then follow a “bench to bedside” approach to acquired brain injury in the preterm and term newborn infant in the next chapters. The contributors, all internationally recognized clinician scientists, provide the clinician reader with a state-of-the art review in their area of expertise. The final section of the book address special populations and concerns, areas that are largely overlooked in existing neurology textbooks. Each of these areas has seen considerable advances in the last five years and is of increasing relevance to the neurologist and neonatologist clinician. The comprehensive nature of each section (from basic science to acute clinical care to outcomes) should appeal broadly to scientists and allied health professionals working in neonatal neurology. Readership Paediatric neurologists, neonatologists, neurologists and paediatricians, clinicians in child development, child health researchers and allied health professionals (in physiotherapy, occupational therapy, speech therapy and psychology). Trainees in these areas.

Preterm Birth

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030910159X
Total Pages : 791 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Preterm Birth by : Institute of Medicine

Download or read book Preterm Birth written by Institute of Medicine and published by National Academies Press. This book was released on 2007-05-23 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. While advances in perinatal and neonatal care have improved survival for preterm infants, those infants who do survive have a greater risk than infants born at term for developmental disabilities, health problems, and poor growth. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. Preterm Birth assesses the problem with respect to both its causes and outcomes. This book addresses the need for research involving clinical, basic, behavioral, and social science disciplines. By defining and addressing the health and economic consequences of premature birth, this book will be of particular interest to health care professionals, public health officials, policy makers, professional associations and clinical, basic, behavioral, and social science researchers.

Neonatal Hematology

Author : Pedro A. de Alarcón
Publisher : Cambridge University Press
ISBN 13 : 1108488986
Total Pages : 501 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Neonatal Hematology by : Pedro A. de Alarcón

Download or read book Neonatal Hematology written by Pedro A. de Alarcón and published by Cambridge University Press. This book was released on 2021-02-18 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.

Pediatric Neurocritical Care

Author : Nicholas S. Abend, MD
Publisher : Demos Medical Publishing
ISBN 13 : 1617050695
Total Pages : 529 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis Pediatric Neurocritical Care by : Nicholas S. Abend, MD

Download or read book Pediatric Neurocritical Care written by Nicholas S. Abend, MD and published by Demos Medical Publishing. This book was released on 2012-11-28 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Pediatric Neurocritical Care is by far the most comprehensive book I have read dealing with this topic... This text will provide an excellent reference for those interested in the pediatric intensive care cases or pediatrics in general. It is written very well and is chock-full of information that Practioners in a pediatric ICU setting would use." --Donna Jacobs, R. EEG T., CNIM, The Neurodiagnostic Journal Caring for children with neurocritical illness often requires multi-specialty collaboration and the understanding of an ever-expanding body of data. This book gives clinicians the up-to-date, concise, and clinically relevant guidance they need to provide optimal care to children with these acute neurologic disorders. The chapters in Pediatric Neurocritical Care are authored by experts in each individual topic, and co-edited by a neurologist and intensivist to ensure that all topics have been fully addressed from both perspectives. The book covers the complete continuum of care from assessment, monitoring, and condition specific management through rehabilitation. Early chapters present differential diagnosis and management approaches to common overarching problems such as coma, headache, and elevated intracranial pressure, followed by chapters focusing on the evaluation and management of specific conditions including traumatic brain injury, stroke, seizures, central nervous system infections, and demyelinating disorders. The final chapters address important associated psychological, social, and ethical issues. To reflect the full spectrum of specialties involved in the burgeoning field of pediatric neurocritical care, the book brings together an international group of experts from multiple disciplines including critical care medicine, anesthesiology, neurology, neurosurgery, rehabilitation medicine, psychology, and pediatric subspecialties. Pediatric Neurocritical Care features: Every topic is addressed from a neurologic and critical care perspective. Comprehensive coverage includes the evaluation of common overarching problems and management of specific conditions, in addition to discussion of related psychological, ethical, and social issues. Chapters are written by internationally known experts from the fields of critical care medicine, anesthesiology, neurology, neurosurgery, rehabilitation medicine, and many affiliated specialties.

The Newborn Brain

Author : Hugo Lagercrantz
Publisher : Cambridge University Press
ISBN 13 : 113948558X
Total Pages : 427 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis The Newborn Brain by : Hugo Lagercrantz

Download or read book The Newborn Brain written by Hugo Lagercrantz and published by Cambridge University Press. This book was released on 2010-01-07 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of the brain and the emergence of the mind constitute some of the most important concerns of contemporary biology. Disturbances during fetal life may have profound implications for a child's future neurological and psychological development, which can in turn impact society. The new edition of this highly respected work presents a comprehensive review of the basic mechanisms of brain development and the pathophysiology of disorders of the infant brain, written by a team of distinguished neuroscientists, neonatologists, and neuropediatricians. The book follows the main milestones of brain development, from formation of the neural tube and wiring of the neurons in the brain. Neurotrophic factors, neurotransmitters, glial cell biology, cerebral circulation development of sensory functions are all described in detail. Furthermore, there are more philosophical chapters on the evolution of the brain and the emergence of consciousness. Clinical considerations are highlighted where relevant.

Neurosurgical Diseases

Author : Leon T. Lai
Publisher : Thieme
ISBN 13 : 1638536392
Total Pages : 641 pages
Book Rating : 4.6/5 (385 download)

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Book Synopsis Neurosurgical Diseases by : Leon T. Lai

Download or read book Neurosurgical Diseases written by Leon T. Lai and published by Thieme. This book was released on 2021-11-17 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: A structured, evidence-based approach to neurosurgical decision-making for brain pathologies Evidence-based neurosurgery is one of the most important pillars upon which to build decision management pathways. Effective delivery of care involves understanding the natural history of the disease and the evidence behind available treatment options. Neurosurgical Diseases: An Evidence-Based Approach to Guide Practice by esteemed neurosurgeons Leon T. Lai, Cristian Gragnaniello, and expert contributors covers cranial pathologies neurosurgeons commonly encounter in everyday practice. The book combines a structured approach to evidence-based neurosurgery with expert opinions, analysis of up-to-date clinical data, understanding of patient preferences and values, and firsthand experiences to facilitate translation of evidence into clinical practice. Twenty-seven consistently formatted chapters are each dedicated to a different disease state, including brain tumors, cerebrovascular disease, Cushing's disease, traumatic brain injury, trigeminal neuralgia, and normal pressure hydrocephalus. All chapters include an introduction, current statistics and data, natural history of the pathology, selected papers for further reading, procedural options and outcomes, and recommended treatment protocols from the authors. Key Features Key content summarized in reader-friendly bullets, diagrams, tables, and illustrative figures enhances acquisition of knowledge Discussion of new developments including treatment recommendations for primary and metastatic brain tumors Statistical data on cerebral aneurysm treatment outcomes and recommendations for treatment New protocols for treating head trauma, closed head injuries, and spontaneous intracranial hemorrhage This essential resource will help neurosurgical residents and junior neurosurgeons make challenging surgical treatment decisions for complex conditions, clearly and concisely and based on the best evidence.

Neonatology

Author : Giuseppe Buonocore
Publisher : Springer
ISBN 13 : 9783319294872
Total Pages : 0 pages
Book Rating : 4.2/5 (948 download)

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Book Synopsis Neonatology by : Giuseppe Buonocore

Download or read book Neonatology written by Giuseppe Buonocore and published by Springer. This book was released on 2018-10-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This landmark book, a reference work now in its second edition, provides healthcare practitioners in neonatology with an up-to-date, comprehensive source of readily accessible practical advice that will assist in the expert management of patients and their diverse illnesses. Leading experts in their fields discuss the underlying causes and mechanisms and all aspects of the treatment of the full range of neonatal diseases and abnormalities, citing the evidence base whenever appropriate. In addition, detailed information is provided on epidemiology and fetal medicine; therapeutic issues such as the organization of care, transport services, and home care after discharge; legal issues; nutrition; and the consequences of medication use during pregnancy, maternal drug abuse and smoking, and maternal diabetes. The inclusion of summaries, tables, and carefully selected guidelines and recommendations will supply practitioners with quick references and instant solutions during daily practice. The book will be a superb resource for all involved in the care of newborn babies, including neonatologists, pediatricians, pediatric surgeons, anesthesiologists, midwives, and nursing staff. It is published within the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.

Volpe's Neurology of the Newborn E-Book

Author : Joseph J. Volpe
Publisher : Elsevier Health Sciences
ISBN 13 : 0443105456
Total Pages : 1845 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Volpe's Neurology of the Newborn E-Book by : Joseph J. Volpe

Download or read book Volpe's Neurology of the Newborn E-Book written by Joseph J. Volpe and published by Elsevier Health Sciences. This book was released on 2024-01-08 with total page 1845 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stay up to date with today’s latest advances in diagnosis and management, as well as the many scientific and technological advances that are revolutionizing neonatal neurology, with the definitive text in the field. Volpe's Neurology of the Newborn, 7th Edition, shares the knowledge and expertise of world authority Dr. Joseph Volpe, who, along with Dr. Terrie E. Inder of Children’s Hospital of Orange County and other distinguished editors, brings a wealth of insight to this classic text. Known for its clear, engaging writing style, vibrant, full-color illustrations, and authoritative information throughout, this reference is an indispensable resource for those who provide care for neonates with neurological conditions. Provides clear, comprehensive coverage of neonatal neurology in Dr. Joseph Volpe’s own legendary, readable manner—for a masterful, cohesive source of answers to any question that arises in your practice. Brings the latest science into the clinical setting, with an emphasis on translating new knowledge to the infant’s bedside. Offers comprehensive updates with summary tables and text to reflect major advances in the study of hemorrhage; new insights into molecular genetics and molecular characterization of brain tumors; significant advances in drugs and the developing nervous system; and much more. Includes new chapters on fetal neurology which address the importance of understanding and investigating the maternal-fetal origins of neonatal disease, as well as new chapters on neurodevelopmental follow-up, inflammation, and neurology in low-resource settings. Contains more than 1,000 illustrations: clinical and pathological specimens, key experimental findings, schematics, algorithms, anatomical drawings, and neuroimaging throughout, as well as numerous tables and boxes that synthesize key points. Any additional digital ancillary content may publish up to 6 weeks following the publication date.