Author : Leonie Bogl
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (125 download)
Book Synopsis P3-05-03 - Maternal Diet During Pregnancy and Child Weight Outcomes by : Leonie Bogl
Download or read book P3-05-03 - Maternal Diet During Pregnancy and Child Weight Outcomes written by Leonie Bogl and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction: Animal studies suggest that maternal diet during pregnancy influences susceptibility to obesity in the next generation. One-carbon nutrients involved in epigenetic processes represent a possible underlying mechanism. Unfortunately, there is limited research in humans to support animal findings, and the few studies available have been limited to birth defects and weight outcomes in early infancy. The aim of this project was to examine the associations between maternal diet (diet quality indicators and one-carbon nutrients) during the period surrounding pregnancy and long-term weight outcomes in the offspring.Methods: We examined 2,729 mother-child pairs from the Nursesu2019 Health Study II and the offspring cohort Growing Up Today Study 2 (GUTS 2). Children, 12-14 years at baseline were 21-23 years at the last follow-up. Overweight was defined for youth less than 18 years of age using sex- and age-specific body mass index (BMI) cut-offs recommended by the International Obesity Task Force and for those 18 years or older as BMI u226525 kg/m2. Dietary information was collected by a validated 131-item food frequency questionnaire (FFQ) and questions on supplement use. Maternal dietary patterns were calculated from FFQs using three diet quality scores u2013 the alternate Healthy Eating Index (aHEI), Alternate Mediterranean Diet (aMED) and Dietary Approach to Stop Hypertension (DASH). Log-binomial models were used to estimate relative risks (RRs) and 95% confidence intervals.Results: In models adjusted for sex, gestational age at delivery and maternal total energy intake, greater maternal adherence to aMED and DASH, but not aHEI, was associated with lower overweight risk in the offspring (RRQ5 vs Q1=0.82 [0.70-0.97] for aMED and 0.86 [0.72-1.04] for DASH) (P for trend