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Osteosarcoma In Adolescents And Young Adults New Developments And Controversies
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Book Synopsis Osteosarcoma in Adolescents and Young Adults: New Developments and Controversies by : G. Bennett Humphrey
Download or read book Osteosarcoma in Adolescents and Young Adults: New Developments and Controversies written by G. Bennett Humphrey and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteosarcoma in Adolescents and Young Adults: New Developments and Controversies is the fifth volume in the series `Cancer Treatment, and Research' devoted to pediatric oncology. Like its immediate predecessor, Hodgkin's Disease in Children: Controversies and Current Practice, this volume also deals with the current state of affairs: where do researchers differ in opinions or firmly held beliefs? What does the future hold for research or for the patients who have benefited from research and are now cured? etc. The first part deals with preclinical and clinical issues that relate to the disease and the second part deals with the results of recent trials and in some cases ongoing trials. It could be argued that section B Pharmacology, Section D Radiotherapy and Section E Surgery of part one belong to part two; however in these sections we have tried to focus on one discipline and in part two, we have tried to focus on the results of multidisciplinary trials. A third part includes a few critiques and editorial comments. This volume was prepared and planned for both basic and clinical oncologists. It is hoped that the basic scientists will gain some insight into the problems of their clinical colleagues and that the clinicians will be willing to read to the more basic articles. It is not a text for students (or for that matter physicians) who want all things to be laid out in `black and white'. But it is a text for those students who want to know how vibrant this field of research is and are willing to stand in awe of how much research needs to be done.
Book Synopsis Diagnostic and Therapeutic Advances in Pediatric Oncology by : David O. Walterhouse
Download or read book Diagnostic and Therapeutic Advances in Pediatric Oncology written by David O. Walterhouse and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of Diagnostic and Therapeutic Advances in Pediatric Oncology for the Cancer Treatment and Research Series is to provide an up-to-date summary of how recent advances in cancer research are being applied to the care of children with solid tumors. The interface of cancer research with clinical practice in pediatric oncology has never been more intimate than today. While researchers are identifying oncogenes and tumor suppressor genes and are studying their specific functions, clinicians are using knowledge of oncogenes and tumor suppressor genes for diagnosing cancer in children, for therapeutic decision-making purposes, and for prognostic purposes. The first three chapters in this book describe models for understanding the causes of childhood cancer that were perhaps initially identified by clinicians and that are now being studied and understood by researchers. These chapters will describe research evidence that supports roles for the involvement of normal developmental regulatory genes in childhood oncogenesis, of abnormal immune regulation in childhood oncogenesis, and of heredity in childhood oncogenesis. The next eight chapters are devoted to descriptions of the appli cation of new research developments to clinical practice with reference to the most common forms of solid tumors of childhood outside the central nervous system. The final chapter will describe late effects of childhood cancer and its therapy and the impact research is having on understanding and perhaps preventing these late effects.
Book Synopsis Pediatric and Adolescent Osteosarcoma by : Norman Jaffe
Download or read book Pediatric and Adolescent Osteosarcoma written by Norman Jaffe and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric and Adolescent Osteosarcoma provides a historical review of the nature of osteosarcoma and the conflict that accompanied the introduction of adjuvant therapy for osteosarcoma culminating in accepted and prevailing methods of current therapy. It outlines concepts in Epidemiology and Etiology, and provides chapters on pathology and radiologic characteristics of osteosarcoma, surgical therapy tailored specifically for treatment of primary tumors in pediatric/adolescent age group, treatment of pulmonary and extra pulmonary metastases and complications, as well as the role of radiation therapy. The volume concludes with a review of differences and similarities in the management of osteosarcoma in adults as compared to pediatrics / adolescents and new laboratory and animal investigations currently in progress to develop effective diagnostic and therapeutic approaches to improve the outcome. In essence the scope and intensive coverage of the book provides a historical perspective of the advances made over the past 30 years and emerging concepts and prospects for new diagnostic and therapeutic approaches. This is based upon past experiences and new discoveries. It also provides a unique opportunity for pediatric and adult medical oncologists, physicians in training, orthopedic surgeons, pathologists, radiologists, radiotherapists, oncology nurses and allied professionals involved in the care of pediatric/adolescent patients with osteosarcoma to become acquainted with prevailing methods of treatment and new and evolving concepts and developments.
Book Synopsis Pediatric Radiation Oncology by : Louis S. Constine
Download or read book Pediatric Radiation Oncology written by Louis S. Constine and published by Lippincott Williams & Wilkins. This book was released on 2016-07-05 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric Radiation Oncology, Sixth Edition continues to be the premier reference that offers comprehensive coverage of this challenging area for the radiation oncologist in training or practice, medical radiation physicists and dosimetrists, as well as pediatric oncologists and others interested in understanding childhood malignancies. This definitive text has been completely updated to reflect recent advances in the field. Manageable in size and engaging to read, it efficiently synthesizes data on pathogenesis, pathology, diagnostic workup, staging, treatment approaches (particularly radiation therapy—indications, doses, volumes, and treatment planning), and toxic outcomes, as well as guidance on decision making when data is lacking. For 30 years, this standard reference has helped demystify radiation therapy for childhood cancer and contributed to the quality and quantity of life for children affected by this disease.
Book Synopsis Recent Advances in Clinical Trial Design and Analysis by : Peter F. Thall
Download or read book Recent Advances in Clinical Trial Design and Analysis written by Peter F. Thall and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials have two purposes -- to treat the patients in the trial, and to obtain information which increases our understanding of the disease and especially how patients respond to treatment. Statistical design provides a means to achieve both these aims, while statistical data analysis provides methods for extracting useful information from the trial data. Recent advances in statistical computing have enabled statisticians to implement very rapidly a broad array of methods which previously were either impractical or impossible. Biostatisticians are now able to provide much greater support to medical researchers working in both clinical and laboratory settings. As our collective toolkit of techniques for analyzing data has grown, it has become increasingly difficult for biostatisticians to keep up with all the developments in our own field. Recent Advances in Clinical Trial Design and Analysis brings together biostatisticians doing cutting-edge research and explains some of the more recent developments in biostatistics to clinicians and scientists who work in clinical trials.
Book Synopsis Pediatric Radiation Oncology by : Edward C. Halperin
Download or read book Pediatric Radiation Oncology written by Edward C. Halperin and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established since 1986 as the definitive text and reference on use of radiation therapy for childhood cancer, Pediatric Radiation Oncology is now in its thoroughly revised and updated Fifth Edition. This edition reviews all significant recent clinical trials—including, for the first time, significant European clinical trials—and provides increased coverage of international and Third World issues. The latest cancer staging guidelines are included. New chapters cover psychosocial aspects of radiotherapy for the child and family and medical management of pain, nausea, nutritional problems, and blood count depression in the child with cancer. This edition also has full-color illustrations throughout. A companion website includes the full text and an image bank.
Book Synopsis Current Catalog by : National Library of Medicine (U.S.)
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1993 with total page 1356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Osteosarcoma written by Manish Agarwal and published by BoD – Books on Demand. This book was released on 2012-04-11 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is aimed at quickly updating the reader on osteosarcoma, a dreaded primary bone cancer. Progress in management of osteosarcoma has been slow after the evolution of chemotherapy and limb salvage surgery. Research is now directed towards identifying molecular targets for systemic therapy. Availability of chemotherapy drugs and low cost implants in developing world have allowed limb salvage surgery to develop. This book looks at current basic knowledge on osteosarcoma and some of the developments in research which have the potential to change the prognosis.
Book Synopsis Advances in Allogeneic Hematopoietic Stem Cell Transplantation by : Richard K. Burt
Download or read book Advances in Allogeneic Hematopoietic Stem Cell Transplantation written by Richard K. Burt and published by Springer. This book was released on 2012-11-28 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of hematopoietic stem cell transplantation is rapidly evolving. Realization that hematopoietic stem cells give rise to the immune compartment has resulted in clinical trials of hematopoietic stem cell transplantation for patients with autoimmune diseases. Allogeneic hematopoietic transplants are a form of adoptive immunotherapy resulting in beneficial graft versus tumor effects. Large numbers of hematopoietic cells can be collected with ease. Therefore, a renewable source of cells for ex vivo genetic manipulations is readily available. Multiple trials combining hematopoietic transplants and gene therapy are in progress. One such application is the infusion of allogeneic lymphocytes containing a suicide gene to abort graft versus host disease. Hematopoietic stem cell transplantation is in reality the clinical and practical application of cellular therapy. Hematopoietic transplant physicians are by design or by practical application evolving into cell and gene therapy specialists. The excitement and enthusiasm in hematopoietic transplantation is that it offers a door to the future. A future not of drugs or titrating poisonous chemotherapy but rather of cellular and gene therapy. 1 ALLOGENEIC PERIPHERAL BLOOD STEM CELL TRANSPLANTATION FOR HEMATOLOGIC DISEASES Martin Korbling University o/Texas MD. Anderson Cancer Center, Houston, Texas 77030 INTRODUCTION Circulating hematopoietic stem cells have emerged as an alternative to bone marrow (BM) stem cells for allografting. For many years the reconstitutive potential of circulating stem cells was questioned; peripheral blood stem cells (PBSC) were even characterized a waste product (1).
Book Synopsis Diagnostic and Therapeutic Advances in Hematologic Malignancies by : Martin S. Tallman
Download or read book Diagnostic and Therapeutic Advances in Hematologic Malignancies written by Martin S. Tallman and published by Springer Science & Business Media. This book was released on 2007-11-23 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is no field of medicine in which advances in therapy have been so closely linked to a better understanding of molecular medicine than in the area of hematologic malignancies. Diagnostic and Therapeutic Advances in Hematologic Malignancies will provide practitioners and academic clinicians with a better understanding of the constant evolving concepts in this area.
Book Synopsis Advances in Radiation Therapy by : Bharat B. Mittal
Download or read book Advances in Radiation Therapy written by Bharat B. Mittal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in radiation oncology have depended upon and are intertwined with subsequent scientific discoveries and the development of new techniques in the fields of radiation and molecular biology, physics, electrical engineering, surgery, and medical oncology. This volume describes how some of the recent discoveries in the radiological sciences have influenced the way radiation oncology is practised. As there are many advances in this field, the Editors have chosen to concentrate on selected topics in clinical radiotherapy, radiation physics and biology, and technical innovations that have had a major impact on radiation oncology in the past twenty years. It is hoped that the techniques described in this volume will increase tumor control and prolong patient survival and at the same time decrease radiation-induced side effects and complications.
Book Synopsis Head and Neck Cancer by : Waun Ki Hong
Download or read book Head and Neck Cancer written by Waun Ki Hong and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the world, head and neck cancer is a major threat to public health and a significant challenge to both clinicians and basic scientists. Despite extensive efforts in primary prevention, screening, early detection, and therapy, long-term survival rates have not improved substantially in the last three decades. This book covers a wide range of exciting new findings in both clinical and basic sciences as they are relevant to head and neck cancer. These findings have recently enhanced our understanding of head and neck carcinogenesis at the genetic and molecular levels, offering the promise of improved preventive and therapeutic strategies. This book will also present information on the important clinical advances that have been made in chemoprevention, organ preservation, and the simultaneous use of chemo therapy and radiotherapy. The first part provides an overview of the etiology and biology of head and neck cancer, including an examination of human papillomaviruses in both benign and malignant lesions. This section also discusses the carcinogenic process at the genetic and molecular levels, as well as aberrant squamous differentiation; increased understanding of these areas has great potential to translate into new strategies for cancer prevention. The second part describes recent advances in developing a risk model for head and neck cancer, as well as the application of genetic susceptibility data in chemoprevention. This section also includes overviews of the status of chemoprevention trials and of the process of invasion and metastasis in head and neck cancer.
Book Synopsis Mammary Tumor Cell Cycle, Differentiation, and Metastasis by : Robert B. Dickson
Download or read book Mammary Tumor Cell Cycle, Differentiation, and Metastasis written by Robert B. Dickson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammary Tumor Cell Cycle, Differentiation and Metastasis is the fifth volume since 1988 in a series designed to broadly examine current advances in the cellular and molecular biology of breast cancer. As in previous volumes, the editors have invited recognized experts in cutting-edge topics to provide a chapter focused on their area of research. The editors have turned to the researchers who study rodent models of the disease and to those who study the cellular and molecular basis of human breast cancer. The first section of the book is devoted to new mouse models of mammary development and tumorigenesis. The second section moves to studies of human breast cancer and focuses on receptors, signalling, and the cell cycle. The final section deals with defective tissue interactions in human breast cancer. We are now in a period of extremely rapid accumulation of data on the molecular and cellular biology of breast cancer. These findings are highlighted in chapters from Mammary Tumor Cell Cycle, Differentiation and Metastasis: Advances in Cellular and Molecular Biology of Breast Cancer.
Book Synopsis Ethical Issues in Cancer Patient Care by : Peter Angelos
Download or read book Ethical Issues in Cancer Patient Care written by Peter Angelos and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses a variety of ethical issues that arise in the care of oncology patients. Many volumes have been written on medical ethics in the past 30 years. However, few have focused on ethical issues specific to the care of cancer patients. This book brings together such a focused examination. The contributors are experienced clinicians, ethicists, medical humanists, and medical educators. The issues raised have direct relevance to the care of oncology patients in treatment as well as research settings. The chapters address issues that are central to contemporary medical practice and medical ethics inquiry. Any practicing clinician will be well aware of the problems of communication and how uncertainty, cross-cultural issues, and religious influences can impact patient care. The limits of care and the role of advance directives and palliative care are common issues that must be addressed in treating patients at the end of life. For oncologists and oncology patients, participation in clinical trials may be a thomy topic, especially when phase I clinical trials are being considered. The impact of managed care and reimbursement issues cannot be avoided in the contemporary patient care and similarly cannot be neglected when considering the ethical ramifications raised. No discussion of ethics in oncology can be complete without attention to the specific challenges raised by the pediatric patient with cancer. All of these topics are explored by the contributors to this book.
Book Synopsis Gastrointestinal Oncology by : A. B. Benson
Download or read book Gastrointestinal Oncology written by A. B. Benson and published by Springer Science & Business Media. This book was released on 1999-02-28 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal tract malignancies encompass a spectrum of diseases with marked differences in etiology, incidence, biological behavior, and treatment outcome. The incidence of new gastrointestinal cases recorded yearly for patients residing in the United States is approximately 230,000, representing nearly 20% of all cancer cases. Worldwide, gastrointestinal malignancies are responsible for the largest number of cancer deaths, particularly because of the high incidence of hepatocellular and gastric cancer in other countries. Gastrointestinal Oncology is directed to those most involved in the multidisciplinary approach to the gastrointestinal cancer patient, including medical, radiation and surgical oncologists; gastroenterologists; interventional radiologists; pathologists; oncology nurses; and oncology physicians-in-training.
Book Synopsis Cancer Policy: Research and Methods by : C.L. Bennett
Download or read book Cancer Policy: Research and Methods written by C.L. Bennett and published by Springer. This book was released on 2007-08-20 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Policy and outcome studies represent a new area of research in oncology. Understanding the factors that affect quality of life, costs of care, patterns of care, and outcomes in oncology is important to providing comprehensive care. Health services is meant to be both a productive area of research as well as a discipline that improves patient decision making. In sum, Cancer Policy highlights some of the important areas of health services research in oncology.
