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Osteochondral Tissue Engineering
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Book Synopsis Articular Cartilage Tissue Engineering by : Kyriacos A. Athanasiou
Download or read book Articular Cartilage Tissue Engineering written by Kyriacos A. Athanasiou and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. Table of Contents: Hyaline Articular Cartilage / Cartilage Aging and Pathology / In Vitro / Bioreactors / Future Directions
Book Synopsis The Soft–Hard Tissue Junction by : Neil D. Broom
Download or read book The Soft–Hard Tissue Junction written by Neil D. Broom and published by Cambridge University Press. This book was released on 2018-11-29 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: Richly illustrated throughout with actual tissue images, this innovative book shows that the soft-hard tissue junction is best understood in a biomechanical context. The authors describe their pioneering experimental methods, providing an essential structure-function framework for computational modelling, and thereby encouraging the development of more realistic, predictive models of this important tissue junction. Covering the three main musculoskeletal junctions of cartilage-bone, disc-vertebra, and ligament/tendon-bone, the relevant soft tissues are examined with respect to both their own inherent structure and their mode of integration with the hard tissue. The soft-hard tissue interface is explored with a focus on structural damage resulting from overloading, and its associated pathologies. Adopting a multiscale approach, ranging in structural resolution from the macro to fibril levels, this is a must-have guide to the field and an ideal resource for researchers seeking new and creative approaches for studying the joint and spine tissues.
Book Synopsis Scaffolding In Tissue Engineering by : Peter X. Ma
Download or read book Scaffolding In Tissue Engineering written by Peter X. Ma and published by CRC Press. This book was released on 2005-08-19 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing interest in scaffolding design and increasing research programs dedicated to regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While certain books and journal articles address various aspects in the field, this is the first current, comprehensive text focusing on scaffolding for tissue engineering.
Book Synopsis Biomedical Product Development: Bench to Bedside by : Babak Arjmand
Download or read book Biomedical Product Development: Bench to Bedside written by Babak Arjmand and published by Springer Nature. This book was released on 2020-02-05 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers all the steps in manufacturing a biomedical product from bench to bedside. It specifically focuses on quality assurance and management and explains the different good practice principles in the various phases of product development as well as how to fulfill them: Good laboratory practice, good manufacturing practice and good clinical practice. It provides readers with the know-how to design biomedical experiments to ensure quality and integrity, to plan and conduct standard preclinical studies and to assure the quality of the final manufactured biomedical products. Importantly, it also addresses ethical concerns and considerations. The book discusses the guidelines and ethical considerations for preclinical and clinical studies, to allow readers to identify safety concerns regarding biomedical products and to improve pre-clinical studies for the development of better products. This textbook is a valuable guide for biomedical students (B.Sc., M.S., and Ph.D. students) in the field of molecular medicine, medical biotechnology, stem cell research and related areas, as well as for professionals such as quality control staff, tissue bankers, policy-makers and health professionals.
Book Synopsis Cellular Solids by : Lorna J. Gibson
Download or read book Cellular Solids written by Lorna J. Gibson and published by Cambridge University Press. This book was released on 1997 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this new edition of their classic work on Cellular Solids, the authors have brought the book completely up to date, including new work on processing of metallic and ceramic foams and on the mechanical, electrical and acoustic properties of cellular solids. Data for commercially available foams are presented on material property charts; two new case studies show how the charts are used for selection of foams in engineering design. Over 150 references appearing in the literature since the publication of the first edition are cited. The text summarises current understanding of the structure and mechanical behaviour of cellular materials, and the ways in which they can be exploited in engineering design. Cellular solids include engineering honeycombs and foams (which can now be made from polymers, metals, ceramics and composites) as well as natural materials, such as wood, cork and cancellous bone.
Book Synopsis Advances In Tissue Engineering by : Julia M Polak
Download or read book Advances In Tissue Engineering written by Julia M Polak and published by World Scientific. This book was released on 2008-08-20 with total page 947 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Tissue Engineering is a unique volume and the first of its kind to bring together leading names in the field of tissue engineering and stem cell research. A relatively young science, tissue engineering can be seen in both scientific and sociological contexts and successes in the field are now leading to clinical reality. This book attempts to define the path from basic science to practical application. A contribution from the UK Stem Cell Bank and opinions of venture capitalists offer a variety of viewpoints, and exciting new areas of stem cell biology are highlighted. With over fifty stellar contributors, this book presents the most up-to-date information in this very topical and exciting field./a
Book Synopsis Bone Tissue Engineering by : Jeffrey O. Hollinger
Download or read book Bone Tissue Engineering written by Jeffrey O. Hollinger and published by CRC Press. This book was released on 2004-10-14 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t
Book Synopsis Joint Function Preservation by : Alberto Gobbi
Download or read book Joint Function Preservation written by Alberto Gobbi and published by Springer Nature. This book was released on 2021-11-03 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This user-friendly, pragmatic book discusses the normal and pathological conditions of the appendicular skeleton, with a focus on the preservation of joint function, providing a detailed overview of strategies for both common and complex joint preservation. The first section covers basic topics, ranging from joints homeostasis and biomechanics, to genetics, bio-orthopedics, tissue engineering and 3D bioprinting. The following sections are each dedicated to a specific joint – its functional anatomy, pathologic conditions, diagnostics and treatment. This book is of interest to orthopedists and sports medicine specialists treating common and complex injuries of the joints.
Book Synopsis Stem Cell and Tissue Engineering by : Song Li
Download or read book Stem Cell and Tissue Engineering written by Song Li and published by World Scientific. This book was released on 2011 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves as a valuable reference book for researchers and students.
Book Synopsis Frontiers in Tissue Engineering by : C.W. Patrick
Download or read book Frontiers in Tissue Engineering written by C.W. Patrick and published by Elsevier. This book was released on 1998-02-20 with total page 717 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Tissue Engineering is a carefully edited compilation of state-of-the-art contributions from an international authorship of experts in the diverse subjects that make up tissue engineering. A broad representation of the medical, scientific, industrial and regulatory community is detailed in the book. The work is an authoritative and comprehensive reference source for scientists and clinicians working in this emerging field. The book is divided into three parts: fundamentals and methods of tissue engineering, tissue engineering applied to specialised tissues, and tissue engineering applied to organs. The text offers many novel approaches, including a detailed coverage of cell-tissue interactions at cellular and molecular levels; cell-tissue surface, biochemical, and mechanical environments; biomaterials; engineering design; tissue-organ function; new approaches to tissue-organ regeneration and replacement of function; ethical considerations of tissue engineering; and government regulation of tissue-engineered products.
Book Synopsis Cartilage Repair and Regeneration by : Alessandro Rozim Zorzi
Download or read book Cartilage Repair and Regeneration written by Alessandro Rozim Zorzi and published by BoD – Books on Demand. This book was released on 2018-02-14 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is the result of a partnership that began in 2011, when I received for the first time the invitation to be the scientific editor of a book on bone grafting, by the still little publisher known as InTech. Now six years later, InTech has grown and thrived. My respect and warm approval for the quality of the publisher's work only increased. The hyaline cartilage is a tissue that challenges tissue engineering and regenerative medicine because of its avascular nature. In the 11 chapters of this book, the reader will find texts written by researchers working on advanced topics related to basic laboratory research, as well as excellent reviews on the clinical use of currently available therapies.
Book Synopsis Sports Injuries of the Foot and Ankle by : Gian Luigi Canata
Download or read book Sports Injuries of the Foot and Ankle written by Gian Luigi Canata and published by Springer. This book was released on 2019-04-12 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in a comprehensive manner the best current treatment options for sports injuries of the foot and ankle. Particular attention is devoted to advanced surgical techniques, with practical and clear explanation of every step of the described procedures. The coverage encompasses management of the full range of ligament, bone and joint, and tendon injuries, and a concluding section addresses special considerations such as outcome assessment and advances in rehabilitation techniques. Foot and ankle injuries are extremely common in athletes and may endanger their sporting activity. The approach to these injuries is constantly evolving with the aim of achieving the best possible functional restoration. In presenting a state of the art update covering all aspects of treatment, this book will be of value for established foot and ankle surgeons, fellows and residents in orthopaedics, and all those involved in sports medicine. The authors are leading international experts renowned within their fields, and the book is published in collaboration with ISAKOS.
Book Synopsis Biomedical Composites by : Luigi Ambrosio
Download or read book Biomedical Composites written by Luigi Ambrosio and published by Elsevier. This book was released on 2009-11-23 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biocomposites are widely used in the medical industry to repair and restore bone, tooth, cartilage skin and other tissues. Biomedical composites, provides a thorough review of the current status, recent progress and future trends in composites for biomedical applications.Part one discusses the fundamentals of biocomposites with chapters on natural composites, design and fabrication of biocomposites, and hard and soft tissue applications of biocomposites. Part two then reviews applications of biocomposites. Chapters discuss composites for bone repair, composite coatings for implants, composites for spinal implants, injectable composites and composites for tissue engineered scaffolds. Chapters in part three discuss the biocompatibility, mechanical behaviour and failure of biocomposites with such topics as cellular response, testing of biocomposites and tribology of biocomposites. Finally part four reviews the future for biocomposites with chapters on nano-structured biocomposites, developing biocomposites as scaffolds and biocomposites in tissue engineering and regenerative medicine.With its distinguished editor and team of international contributors, Biomedical composites is an essential reference to materials scientists and researchers in industry and academia, as well as all those concerned with this increasingly important field. - Provides a thorough review of the current status, recent progress and future trends in composites for biomedical applications - Discusses the fundamentals of biocomposites with chapters on natural composites, design and fabrication of biocomposites and their applications - Chapters address composites for bone repair, spinal implants and various other applications and discuss biocompatability, mechanical behaviour and failure of biocomposites
Book Synopsis Joint Preservation of the Knee by : Adam B. Yanke
Download or read book Joint Preservation of the Knee written by Adam B. Yanke and published by Springer. This book was released on 2019-02-11 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprised of clinical cases demonstrating strategies for both common and complex knee preservation, this concise, practical casebook will provide orthopedic surgeons with the best real-world strategies to properly manage the many kinds of knee injuries and disorders they may encounter. The opening section presents the knee joint as a unique structure, reviewing the anatomy and function of articular cartilage and the meniscus, the effects of joint malalignment, the role of the synovium, and how joint failure is defined. The next two sections are comprised of clinical cases with a unique presentation, followed by a description of the diagnosis, assessment and management techniques used to treat it, as well as the case outcome, and clinical pearls and pitfalls. Cases included illustrate small and large cartilage defects, osteochondritis dessicans, chondral defects and lesions, meniscal allograft transplantation, and tibial and tibiofemoral cartilage defects, among others. The final section examines the current evidence for the treatment of articular cartilage lesions and emerging techniques in knee joint preservation and cartilage restoration. Pragmatic and reader-friendly, Joint Preservation of the Knee: A Clinical Casebook is an excellent resource for orthopedic surgeons and sports medicine specialists treating common and complex injuries of the knee.
Book Synopsis Bone and Cartilage Regeneration by : Phuc Van Pham
Download or read book Bone and Cartilage Regeneration written by Phuc Van Pham and published by Springer. This book was released on 2017-01-24 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.
Book Synopsis Cell Engineering and Regeneration by : Heinz Redl
Download or read book Cell Engineering and Regeneration written by Heinz Redl and published by Springer. This book was released on 2017-02-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.
Book Synopsis Plastic and Reconstructive Surgery by : Maria Z. Siemionow
Download or read book Plastic and Reconstructive Surgery written by Maria Z. Siemionow and published by Springer. This book was released on 2015-01-12 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a paradigm shift in plastic and reconstructive surgery from the interest of developing new surgical techniques into the application of new technologies via research based studies on stem cells, tissue engineering and new field of reconstructive transplantation such as e.g. face, hand or larynx transplants. This approach is relatively novel and introduced to plastic surgery within past decade. Thus there is an urgent need to facilitate access to this new knowledge which was not traditionally a part of plastic surgery curriculum. The most efficient way of introducing these new approaches is via presentation of pertinent to different fields (stem cell, transplantation, nerve regeneration, tissue engineering) experimental models which can be used as a tool to develop technologies of interest by different groups of surgeons. These surgical specialities which will be interested and benefit from the book include: plastic and reconstructive surgeons, microsurgeons, hand surgeons, orthopaedic surgeons, neurosurgeons and transplant surgeons.
