Organ Regeneration Based On Developmental Biology

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Developmental Biology and Musculoskeletal Tissue Engineering

Author : Martin J. Stoddart
Publisher : Academic Press
ISBN 13 : 0128115386
Total Pages : 272 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Developmental Biology and Musculoskeletal Tissue Engineering by : Martin J. Stoddart

Download or read book Developmental Biology and Musculoskeletal Tissue Engineering written by Martin J. Stoddart and published by Academic Press. This book was released on 2018-04-24 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies. Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells. - Brings the fields of tissue engineering and developmental biology together to explore the potential for regenerative medicine-based research to contribute to enhanced clinical outcomes - Initial chapters provide an outline of the development of the musculoskeletal system in general, and later chapters focus on specific tissues - Addresses the effect of mechanical forces on the musculoskeletal system during development and the relevance of these processes to tissue engineering - Discusses the role of genes in the development of musculoskeletal tissues and their potential use in tissue engineering - Describes how developmental biology is being used to influence and guide tissue engineering approaches for cartilage, bone, disc, and tendon repair

Stem Cells and the Future of Regenerative Medicine

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309170427
Total Pages : 112 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Stem Cells and the Future of Regenerative Medicine by : Institute of Medicine

Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Principles of Regenerative Medicine

Author : Anthony Atala
Publisher : Academic Press
ISBN 13 : 0123814235
Total Pages : 1203 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Principles of Regenerative Medicine by : Anthony Atala

Download or read book Principles of Regenerative Medicine written by Anthony Atala and published by Academic Press. This book was released on 2010-12-16 with total page 1203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs

Organ Regeneration Based on Developmental Biology

Author : Takashi Tsuji
Publisher : Springer
ISBN 13 : 981103768X
Total Pages : 264 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Organ Regeneration Based on Developmental Biology by : Takashi Tsuji

Download or read book Organ Regeneration Based on Developmental Biology written by Takashi Tsuji and published by Springer. This book was released on 2017-03-30 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews three-dimensional (3D) stem cell culture and proof of concept for organ regeneration. The chapters present studies based on developmental biology but not tissue engineering using bio-degradative scaffolds. The ultimate goal of regenerative therapy, the next generation of regenerative therapy, is to develop fully functioning bioengineered 3D organs that can replace lost or damaged organs following disease, injury, or aging. Next-generation regenerative therapy will consist of organ-replacement regenerative therapy, which aims to reproduce reciprocal epithelial and epithelial interactions and epithelial and mesenchymal interactions that occur during embryogenesis. The book then discusses the generation of several 3D functional organs and organoids such as brain, inner ear, tooth, hair, salivary glands, lacrimal glands, gastrointestinal organs, kidney, liver, and lung. This work will appeal to a wide readership such as medical scientists, developmental biologists, clinicians, and patients. The volume provides valuable information and ideas to form a next-generation field of science.

Developmental Biology: A Very Short Introduction

Author : Lewis Wolpert
Publisher : Oxford University Press
ISBN 13 : 0199601194
Total Pages : 153 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Developmental Biology: A Very Short Introduction by : Lewis Wolpert

Download or read book Developmental Biology: A Very Short Introduction written by Lewis Wolpert and published by Oxford University Press. This book was released on 2011-08-25 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A concise account of what we know about development discusses the first vital steps of growth and explores one of the liveliest areas of scientific research."--P. [2] of cover.

Principles of Regenerative Biology

Author : Bruce M. Carlson
Publisher : Elsevier
ISBN 13 : 0080477968
Total Pages : 400 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Principles of Regenerative Biology by : Bruce M. Carlson

Download or read book Principles of Regenerative Biology written by Bruce M. Carlson and published by Elsevier. This book was released on 2011-10-10 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the explosion of knowledge from molecular biology and the burgeoning interest in generating or regenerating tissues or organs through various bioengineering or stem cell approaches, many scientists and students have shown a renewed interest in the phenomenon of regeneration. Because relatively few have had the luxury of being able to approach the phenomenon of regeneration from a broad biological perspective, Dr. Carlson has produced a book that outlines the fundamental principles of regeneration biology. Subject matters focus principally on regeneration in vertebrate systems, but also invertebrate regeneration. In order to manipulate regenerative processes, it is important to understand the underlying principles of regeneration. Principles of Regnerative Biology is the key introductory reference for all developmental biologists, geneticists, and tissue and stem cell researchers. - Creates a general understanding of one of the most fascinating and complex phenomena in biology - Discusses the ability and diversity of regeneration in various organisms - Explains the history and origins of cells in regenerating systems - Includes information on stem cells and its important role in regeneration

Organ Regeneration

Author : Takashi Tsuji
Publisher : Humana Press
ISBN 13 : 9781493969470
Total Pages : 248 pages
Book Rating : 4.9/5 (694 download)

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Book Synopsis Organ Regeneration by : Takashi Tsuji

Download or read book Organ Regeneration written by Takashi Tsuji and published by Humana Press. This book was released on 2017-03-31 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides readers with a better understanding of organogenesis in developmental biology and next-generation organ regenerative therapy. This book focuses on recent studies of organ regeneration from stem cells using in vitro 3D cell culture and manipulation. The chapters cover topics such as generation of a 3D retinal tissue formation; functional salivary gland regeneration; liver regeneration using cultures liver bud; and in vivo model of small intestine. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and thorough, Organ Regeneration: 3D Stem Cell Culture and Manipulation is a valuable resource for scientists and researchers who are interested in this field.

Stem Cells & Regenerative Medicine

Author : Krishnarao Appasani
Publisher : Springer Science & Business Media
ISBN 13 : 1607618605
Total Pages : 632 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Stem Cells & Regenerative Medicine by : Krishnarao Appasani

Download or read book Stem Cells & Regenerative Medicine written by Krishnarao Appasani and published by Springer Science & Business Media. This book was released on 2010-11-01 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.

Introduction to Epigenetics

Author : Renato Paro
Publisher : Springer Nature
ISBN 13 : 3030686701
Total Pages : 215 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Introduction to Epigenetics by : Renato Paro

Download or read book Introduction to Epigenetics written by Renato Paro and published by Springer Nature. This book was released on 2021-03-23 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease

Developmental Biology

Author : Norman John Berrill
Publisher :
ISBN 13 :
Total Pages : 552 pages
Book Rating : 4.:/5 (5 download)

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Book Synopsis Developmental Biology by : Norman John Berrill

Download or read book Developmental Biology written by Norman John Berrill and published by . This book was released on 1971 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essential Current Concepts in Stem Cell Biology

Author : Beate Brand-Saberi
Publisher : Springer Nature
ISBN 13 : 3030339238
Total Pages : 247 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Essential Current Concepts in Stem Cell Biology by : Beate Brand-Saberi

Download or read book Essential Current Concepts in Stem Cell Biology written by Beate Brand-Saberi and published by Springer Nature. This book was released on 2020-01-03 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes the biology of different adult stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal and cord blood stem cells and also covers induced pluripotent stem cells. Further, it includes a chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material. Based on the international masters program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and Tongji University Shanghai, the book is a valuable source for postdocs and researchers working with stems cells and also offers essential insights for physicians and dentists wishing to expand their knowledge. This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.

Regenerative Biology and Medicine

Author : David L. Stocum
Publisher : Academic Press
ISBN 13 : 012384861X
Total Pages : 474 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Regenerative Biology and Medicine by : David L. Stocum

Download or read book Regenerative Biology and Medicine written by David L. Stocum and published by Academic Press. This book was released on 2012-06-07 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative Biology and Medicine, Second Edition — Winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — discusses the fundamentals of regenerative biology and medicine. It provides a comprehensive overview, which integrates old and new data into an ever-clearer global picture. The book is organized into three parts. Part I discusses the mechanisms and the basic biology of regeneration, while Part II deals with the strategies of regenerative medicine developed for restoring tissue, organ, and appendage structures. Part III reflects on the achievements of regenerative biology and medicine; future challenges; bioethical issues that need to be addressed; and the most promising developments in regenerative medicine. The book is designed for multiple audiences: undergraduate students, graduate students, medical students and postdoctoral fellows, and research investigators interested in an overall synthesis of this field. It will also appeal to investigators from fields not directly related to regenerative biology and medicine, such as chemistry, informatics, computer science, mathematics, physics, and engineering. - Highly Commended 2013 BMA Medical Book Award for Medicine - Includes coverage of skin, hair, teeth, cornea, and central neural tissues - Provides description of regenetive medicine in digestive, respiratory, urogenital, musculoskeletal, and cardiovascular systems - Includes amphibians as powerful research models with discussion of appendage regeneration in amphibians and mammals

Tissue and Organ Regeneration in Adults

Author : Ioannis V. Yannas
Publisher : Springer
ISBN 13 : 9781441929099
Total Pages : 0 pages
Book Rating : 4.9/5 (29 download)

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Book Synopsis Tissue and Organ Regeneration in Adults by : Ioannis V. Yannas

Download or read book Tissue and Organ Regeneration in Adults written by Ioannis V. Yannas and published by Springer. This book was released on 2010-12-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue engineering is the first discipline of bioengineering which explicitly integrates molecular biology with physics and chemistry. It emphasizes research in the synthesis of new tissues and organs in vivo and in vitro. The treatment is uniform and deliberately directed toward the different backgrounds of students from the physical and life sciences. The book also features an extensive bibliography, and extensive bodies of independent data on organ regeneration from the journal literature. In short, the generic organ-blind methodology described in this volume should be useful to most students and practitioners of tissue engineering.

Epigenetics and Regeneration

Author :
Publisher : Academic Press
ISBN 13 : 0128148802
Total Pages : 544 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Epigenetics and Regeneration by :

Download or read book Epigenetics and Regeneration written by and published by Academic Press. This book was released on 2019-05-24 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming. As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics. - Provides a foundational overview of epigenetics in regenerative medicine - Examines epigenetic components of tissue regeneration for a variety of organ systems and tissue types, as well as current attempts to employ these mechanisms in clinical practice - Offers researchers, students, clinicians, and pharmacologists the tools they need to enhance tissue development, repair, homeostasis, and regeneration and explore new epigenetic therapeutic pathways - Features chapter contributions from leading international researchers and clinicians in the fields of epigenetics and regenerative medicine

Regenerative Medicine and Stem Cell Biology

Author : Nagwa El-Badri
Publisher : Springer Nature
ISBN 13 : 3030553590
Total Pages : 374 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Regenerative Medicine and Stem Cell Biology by : Nagwa El-Badri

Download or read book Regenerative Medicine and Stem Cell Biology written by Nagwa El-Badri and published by Springer Nature. This book was released on 2020-11-27 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers the basic aspects of stem cell research and applications in regenerative medicine. Each chapter includes a didactic component and a practical section. The book offers readers insights into: How to identify the basic concepts of stem cell biology and the molecular regulation of pluripotency and stem cell development. How to produce induced pluripotent stem cells (iPSCs) and the basics of transfection. The biology of adult stem cells, with particular emphasis on mesenchymal stromal cells and hematopoietic stem cells, and the basic mechanisms that regulate them. How cancer stem cells arise and metastasize, and their properties. How to develop the skills needed to isolate, differentiate and characterize adult stem The clinical significance of stem cell research and the potential problems that need to be overcome. Evaluating the use of stem cells for tissue engineering and therapies (the amniotic membrane) The applications of bio-nanotechnology in stem cell research. How epigenetic mechanisms, including various DNA modifications and histone dynamics, are involved in regulating the potentiality and differentiation of stem cells. The scientific methods, ethical considerations and implications of stem cell research.

Strategies in Regenerative Medicine

Author : Matteo Santin
Publisher : Springer Science & Business Media
ISBN 13 : 0387746609
Total Pages : 515 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Strategies in Regenerative Medicine by : Matteo Santin

Download or read book Strategies in Regenerative Medicine written by Matteo Santin and published by Springer Science & Business Media. This book was released on 2009-02-28 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: The profound transformations occurred in our modern age have been made possible by the unique combination of new technologies. Among them, me- cine has completely changed our perception of life. Longevity has been signi- cantly extended and linked to new lifestyles. The negative impact that pathologies and ageing have always had on the quality of our life is now mitigated by the availability of treatments daily applied to many individuals worldwide. For many years, pharmacological and surgical treatments have been supported by the introduction of biomedical devices. Biomedical implants have played a key role in the development of these treatments and achieved the objective of replacing tissue and organ structures and functionalities. Gra- ally, the scientific and clinical communities have understood that replacement could be improved by materials able to interact with the tissues and to parti- pate in their metabolism and functions. This approach soon led to biomedical implants with improved clinical performances, but also to a new aspiration; rather than replacing damaged tissues and organs scientists and clinicians nowadays aim at their partial or complete regeneration. As a consequence of this ambition, the disciplines of tissue engineering and regenerative medicine have recently emerged. It is the dawn of a fascinating era where scientists from various disciplines, clinicians, and industry will need to intensify their col- borative efforts to provide our society with new and affordable solutions.

Organ Development

Author :
Publisher : Academic Press
ISBN 13 : 0128104902
Total Pages : 504 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Organ Development by :

Download or read book Organ Development written by and published by Academic Press. This book was released on 2019-02-21 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organ Development, Volume 132, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapter written by an international board of authors. This volume highlights cogent reviews of the development, maintenance and regeneration/repair of several organ systems, from eye to kidney, to the musculoskeletal system. Many reviews highlight new techniques or technologies that are currently pushing the field. The role of both embryonic and adult stem cells are highlighted and senior authors are all women scientists. - Provides the authority and expertise of leading contributors from an international board of author - Presents the latest release in this series - Updated release includes the latest information on organ development