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Author : Bruce Jaegar
Publisher :
ISBN 13 :
Total Pages : 180 pages
Book Rating : 4.3/5 (91 download)
Download or read book Pesticide Assessment Guidelines written by Bruce Jaegar and published by . This book was released on 1984 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Peter A. McAnulty
Publisher : CRC Press
ISBN 13 : 1439811180
Total Pages : 713 pages
Book Rating : 4.4/5 (398 download)
Download or read book The Minipig in Biomedical Research written by Peter A. McAnulty and published by CRC Press. This book was released on 2011-12-19 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Minipig in Biomedical Research is a comprehensive resource for research scientists on the potential and use of the minipig in basic and applied biomedical research, and the development of drugs and chemicals. Written by acknowledged experts in the field, and drawing on the authors’ global contacts and experience with regulatory authorities and the pharmaceutical and other industries, this accessible manual ranges widely over the biological, scientific, and practical uses of the minipig in the laboratory. Its coverage extends from the minipig’s origins, anatomy, genetics, immunology, and physiology to its welfare, health, and husbandry; practical dosing and examination procedures; surgical techniques; and all areas of toxicity testing and the uses of the minipig as a disease model. Regulatory aspects of its use are considered. The reader will find an extensive amount of theoretical and practical information in the pharmacology; ADME and toxicology chapters which will help scientists and managers when deciding which species to use in basic research; drug discovery and pharmacology; and toxicology studies of chemicals, biotechnology products and devices. The book discusses regulatory uses of minipigs in the evaluation of human and veterinary pharmaceuticals, medical devices, and other classes of xenobiotics. It describes features of normal health, normal laboratory values, and common diseases. It also carefully elucidates ethical and legal considerations in their supply, housing, and transport. The result is an all-inclusive and up to date manual about the experimental uses of the minipig that describes ‘How to’ and ‘Why’ and ’What to expect in the normal’, combining enthusiasm and experience with critical assessment of its values and potential problems.
Author : United States. Food and Drug Administration
Publisher :
ISBN 13 :
Total Pages : 124 pages
Book Rating : 4.:/5 (35 download)
Download or read book Appraisal of the Safety of Chemicals in Foods, Drugs, and Cosmetics written by United States. Food and Drug Administration and published by . This book was released on 1959 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : S. Matsunaka
Publisher : Elsevier
ISBN 13 : 1483150453
Total Pages : 582 pages
Book Rating : 4.4/5 (831 download)
Download or read book Mode of Action, Metabolism and Toxicology written by S. Matsunaka and published by Elsevier. This book was released on 2013-10-22 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pesticide Chemistry: Human Welfare and the Environment, Volume 3: Mode of Action, Metabolism and Toxicology covers the proceeding of the Fifth International Congress of Pesticide Chemistry. This book is organized into three parts that tackle relevant issues regarding the use of pesticide. The opening part tackles topics relevant to the biochemistry of pests and mode of action of pesticides, such as influence of chlorinated and parathyroid insecticide on cellular calcium regulatory mechanisms; behavioral and lethal actions of amidines on invertebrates; and insect chitin synthetase as biochemical probe for insecticidal compounds. The second part encompasses metabolism and degradation of pesticides and xenobiotics and includes topics on propesticides; selective toxicity conferred by activation; and comparative biochemistry of animal, plant, and microorganism oxidases. The last part covers the toxicology of pesticides and xenobiotics, including the role of biochemical studies in modern toxicological assessment of pesticides; neurophysiological and behavioral assessment of pesticide toxicity; and genetic toxicology applied to the assessment of mutagenic, carcinogenic, and teratogenic action of pesticides and related compounds. This book will be of great interest to chemists, biologists, botanists, and entomologists or professionals whose line of work involves the use of pesticides and who are concerned with pesticide side-effects to the users and the environment.
Author : George Whitaker Ware
Publisher :
ISBN 13 : 9780913702581
Total Pages : 386 pages
Book Rating : 4.7/5 (25 download)
Download or read book The Pesticide Book written by George Whitaker Ware and published by . This book was released on 1994-01-01 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael J. Derelanko
Publisher : CRC Press
ISBN 13 : 1439890145
Total Pages : 1016 pages
Book Rating : 4.4/5 (398 download)
Download or read book Handbook of Toxicology written by Michael J. Derelanko and published by CRC Press. This book was released on 2014-03-07 with total page 1016 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Toxicology, Third Edition provides an updated practical reference source for practicing toxicologists in the pharmaceutical and chemical industries, contract laboratories, regulatory agencies, and academia. Written by experts in their specific toxicology fields, the chapters provide both fundamental and applied information. Topics r
Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264067396
Total Pages : 26 pages
Book Rating : 4.2/5 (64 download)
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 426: Developmental Neurotoxicity Study written by OECD and published by OECD Publishing. This book was released on 2007-10-15 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt: A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development. The test substance is administered daily, generally orally, to mated females (rats are ...
Author : Mohamed Abou-Donia
Publisher : John Wiley & Sons
ISBN 13 : 1119940419
Total Pages : 716 pages
Book Rating : 4.1/5 (199 download)
Download or read book Mammalian Toxicology written by Mohamed Abou-Donia and published by John Wiley & Sons. This book was released on 2015-05-04 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammalian Toxicology surveys chemical agents and examines how such chemicals impact on human health, emphasizing the importance in minimizing environmental exposure to chemical and physical hazards in our homes, communities and workplaces through such media as contaminated water, soil and air. Starting with the basic principles on a wide range of toxic agents, this textbook describes how they enter the body, their mechanisms of action once inside, and strategies for diagnosis, prevention and treatment. Topics covered include: General principles of toxicology: pharmacological and toxicological principles underpinning the study of toxicology, risk assessments and mechanisms of cell death Disposition: routes of chemical exposures, entry into the body and various tissues, storage, metabolic biotransformation and elimination, with examples from various toxicants. Toxic agents: the occurrences, disposition in the body, health effects, toxic mechanisms, antidotes and treatments of a range of agents including pesticides, metals, solvents, gases, nanomaterials, food components and additives, pharmaceuticals, drugs of abuse, natural toxins, endocrine disruptors, radiation, and warfare weapons. Toxic effects: including neurotoxicity, developmental toxicity, immunotoxicity, teratogenecity, male and female reproductive toxicity, mutagenecity, carcinogenicity, pulmonary toxicity, cardiovascular toxicity, hepatotoxicity, gastrointestinal toxicity and cardiovascular toxicity Toxicology and society: epidemiological studies of chemical-induced diseases in human populations, and a vision for toxicology in the 21st century. Mammalian Toxicology is an essential primer for students of toxicology, biochemistry, biology, medicine and chemistry. It is also appropriate for professional toxicologists in research or regulatory affairs, and anyone who needs to understand the adverse effects of toxic agents on the human body.
Author : Willa Y. Garner
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 600 pages
Book Rating : 4.:/5 (45 download)
Download or read book Good Laboratory Practice Standards written by Willa Y. Garner and published by Oxford University Press, USA. This book was released on 1992 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experienced quality assurance (QA) professionals and field laboratory researchers. Provides concrete ideas for establishing a compliance program and refining the compliance process. Outlines approaches that have resulted in successful compliance and describes methods of avoiding some of the common mistakes. Appendices contain the entire GLP Enforcement Response Policy, a question-and-answer section, examples of forms for submitting data to the EPA, and the EPA's penalty policy.
Author : Mike E. Tumbleson
Publisher : Springer Science & Business Media
ISBN 13 : 9780306454967
Total Pages : 510 pages
Book Rating : 4.4/5 (549 download)
Download or read book Advances in Swine in Biomedical Research written by Mike E. Tumbleson and published by Springer Science & Business Media. This book was released on 1996 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains papers from the October 1995 symposium, in sections on methods and techniques, and nutrition. Subjects include the Yucatan miniature pig model of ventricular septal defect, the minipig as a model for the study of aging in humans, an external thoracic duct venous shunt to allow for long-term
