Off Target

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Off Target

Author : Eve Smith
Publisher : Orenda Books
ISBN 13 : 1914585038
Total Pages : 363 pages
Book Rating : 4.9/5 (145 download)

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Book Synopsis Off Target by : Eve Smith

Download or read book Off Target written by Eve Smith and published by Orenda Books. This book was released on 2021-12-17 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: When a one-night stand leads to a long-desired pregnancy, Susan will do anything to ensure her husband won't find out ... including the unthinkable. But when something horrendous is unleashed around the globe, her secret isn't the only thing that is no longer safe... –––––––––––––––––––––––– A longed-for baby An unthinkable decision A deadly mistake In an all-too-possible near future, when genetic engineering has become the norm for humans, not just crops, parents are prepared to take incalculable risks to ensure that their babies are perfect ... altering genes that may cause illness, and more... Susan has been trying for a baby for years, and when an impulsive one-night stand makes her dream come true, she'll do anything to keep her daughter and ensure her husband doesn't find out ... including the unthinkable. She believes her secret is safe. For now. But as governments embark on a perilous genetic arms race and children around the globe start experiencing a host of distressing symptoms – even taking their own lives – something truly horrendous is unleashed. Because those children have only one thing in common, and people are starting to ask questions... Bestselling author of The Waiting Rooms, Eve Smith returns with an authentic, startlingly thought-provoking, disturbing blockbuster of a thriller that provides a chilling glimpse of a future that's just one modification away... –––––––––––––––––––––––– Praise for The Waiting Rooms 'Combines the excitement of a medical thriller À la Michael Crichton with sensitive characterisation and social insight in a timely debut novel all the more remarkable for being conceived and written before the current pandemic' Guardian 'STUNNING and terrifying ... The Waiting Rooms wrenches your heart in every way possible, but written with such humanity and emotion' Miranda Dickinson 'Chillingly close to reality, this gripping thriller brims with authenticity ... a captivating, accomplished and timely debut from an author to watch' Adam Hamdy 'Engrossing and eye-opening, with heart-stopping plot twists ... a stunning medical thriller set in a terrifying possible future' Foreword Reviews 'A touching, gut-wrenching story of family mystery and tragedy ... a thriller that punches on two fronts – heart AND mind' The Sun 'Gripping and disturbing ... the medical research is convincing, the scenarios plausible, and the story is emotionally engaging. This is an incredible debut!' Gill Paul 'If the themes are dark and topical, the writing is exquisite. Breath held, I got to the finale with my heart in my mouth. Eve Smith weaves a complex and clever tale, merging countries and timelines; the result is a superb and satisfying novel' Louise Beech 'Margaret Atwood is one of my all-time writing heroes and The Handmaid's Tale is probably the best book I've ever read. Eve Smith and The Waiting Rooms really do challenge that long-held crown...' Random Things through My Letterbox 'Thoroughly engaging ... an eye-opening read’ Crime Fiction Lover ‘A novel of our times’ Trip Fiction ‘Haunting, honest and horrifying in its reality … An epic and thrilling read’ Book Literati

Off Target

Author : Jill Ammon Vanderwood
Publisher : Human Rights Watch
ISBN 13 :
Total Pages : 134 pages
Book Rating : 4./5 ( download)

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Book Synopsis Off Target by : Jill Ammon Vanderwood

Download or read book Off Target written by Jill Ammon Vanderwood and published by Human Rights Watch. This book was released on 2019-01-28 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: What would you do if your friend showed you a gun?You are new in town and it's your first day at a new school. Your neighbor, Trevor introduces you to a group of three boys and two girls. Right away you notice that Eric, one of the guys in the group, is being bullied at school. When you go to Eric's house with your new friends, he shows the group a fully loaded handgun that is left in his mother's nightstand. You are faced with some hard choices when someone suggests that Eric should take the gun to school.___________________________________________What should you do? It's time to choose a path: If you're worried that Eric will take the gun to school-continue on page 7.If you decide to take the gun to prevent anyone from being hurt-continue on page 9.If you leave the house with the others and plan to come back for target practice the next day-continue on page 10.____________________________________________Off Target is the first book in The Path You Choose series. You, the reader determine the outcome by the choices you make. Once you read one story, go back and choose a different story. There are thirteen possible endings in this book.What path will you choose

The Waiting Rooms

Author : Eve Smith
Publisher : Orenda Books
ISBN 13 : 1913193276
Total Pages : 400 pages
Book Rating : 4.9/5 (131 download)

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Book Synopsis The Waiting Rooms by : Eve Smith

Download or read book The Waiting Rooms written by Eve Smith and published by Orenda Books. This book was released on 2020-04-09 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Swinging from South Africa to England: one woman's hunt for her birth mother in an all-too-believable near future in which an antibiotic crisis has decimated the population. A prescient, thrilling debut. 'Combines the excitement of a medical thriller à la Michael Crichton with sensitive characterisation and social insight in a timely debut novel all the more remarkable for being conceived and written before the current pandemic' Guardian 'STUNNING and terrifying ... The Waiting Rooms wrenches your heart in every way possible, but written with such humanity and emotion' Miranda Dickinson 'Chillingly close to reality, this gripping thriller brims with authenticity ... a captivating, accomplished and timely debut from an author to watch' Adam Hamdy ________________ Decades of spiralling drug resistance have unleashed a global antibiotic crisis. Ordinary infections are untreatable, and a scratch from a pet can kill. A sacrifice is required to keep the majority safe: no one over seventy is allowed new antibiotics. The elderly are sent to hospitals nicknamed 'The Waiting Rooms' ... hospitals where no one ever gets well. Twenty years after the crisis takes hold, Kate begins a search for her birth mother, armed only with her name and her age. As Kate unearths disturbing facts about her mother's past, she puts her family in danger and risks losing everything. Because Kate is not the only secret that her mother is hiding. Someone else is looking for her, too. Sweeping from an all-too-real modern Britain to a pre-crisis South Africa, The Waiting Rooms is epic in scope, richly populated with unforgettable characters, and a tense, haunting vision of a future that is only a few mutations away. ________________ 'Engrossing and eye-opening, with heart-stopping plot twists ... a stunning medical thriller set in a terrifying possible future' Foreword Reviews 'A touching, gut-wrenching story of family mystery and tragedy ... a thriller that punches on two fronts – heart AND mind' The Sun 'Gripping and disturbing ... the medical research is convincing, the scenarios plausible, and the story is emotionally engaging. This is an incredible debut!' Gill Paul 'If the themes are dark and topical, the writing is exquisite. Breath held, I got to the finale with my heart in my mouth. Eve Smith weaves a complex and clever tale, merging countries and timelines; the result is a superb and satisfying novel' Louise Beech 'Margaret Atwood is one of my all-time writing heroes and The Handmaid's Tale is probably the best book I've ever read. Eve Smith and The Waiting Rooms really do challenge that long-held crown...' Random Things through My Letterbox 'Thoroughly engaging ... an eye-opening read' Crime Fiction Lover 'A novel of our times' Trip Fiction 'Haunting, honest and horrifying in its reality ... An epic and thrilling read' Book Literati 'Stunning dystopian debut. A prescient and alarming tale that seems just a whisper from reality' Suzy Apsley ' The Waiting Rooms will certainly distract us from the real world for a few hours and this is the immeasurable value of fiction. It gives hope that, as in Eve Smith's fictitious world, the possibility of a happy ending still exists' Die Burger ' The Waiting Rooms is a seriously impressive debut, a novel that is intuitive and chilling, one that will resonate with all in this current climate' Swirl & Thread

Pete the Cat's Groovy Imagination

Author : James Dean
Publisher : HarperCollins
ISBN 13 : 0062974122
Total Pages : 40 pages
Book Rating : 4.0/5 (629 download)

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Book Synopsis Pete the Cat's Groovy Imagination by : James Dean

Download or read book Pete the Cat's Groovy Imagination written by James Dean and published by HarperCollins. This book was released on 2021-09-07 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Instant New York Times Bestseller! When a cloudy gray sky cancels Pete the Cat’s beach day plans, a big box is all he needs to beat the rainy-day blues. Pete the Cat wants to go surfing, but he looks outside and—oh no!—it’s gray and rainy. Does Pete get sad? No, he doesn’t! Instead, he finds a really big and GROOVY box. Find out in this epic adventure just where Pete’s imagination takes him. From the authors of the #1 New York Times bestselling Pete the Cat series, James and Kimberly Dean, this out-of-the-box picture book is reminiscent of Pete favorites like Magic Sunglasses and perfect for fans of Not a Box by Antoinette Portis. Don't miss Pete's other adventures, including Pete the Cat: I Love My White Shoes, Pete the Cat: Rocking in My School Shoes, Pete the Cat and His Four Groovy Buttons, Pete the Cat Saves Christmas, Pete the Cat and His Magic Sunglasses, Pete the Cat and the Bedtime Blues, Pete the Cat and the New Guy, Pete the Cat and the Cool Cat Boogie, Pete the Cat and the Missing Cupcakes, and Pete the Cat and the Perfect Pizza Party, and Pete the Cat: Crayons Rock!.

Genome Editing and Engineering

Author : Krishnarao Appasani
Publisher : Cambridge University Press
ISBN 13 : 1107170370
Total Pages : 535 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Genome Editing and Engineering by : Krishnarao Appasani

Download or read book Genome Editing and Engineering written by Krishnarao Appasani and published by Cambridge University Press. This book was released on 2018-08-23 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete guide to endonuclease-based genomic engineering, from basic science to application in disease biology and clinical treatment.

Genome Stability

Author : Igor Kovalchuk
Publisher : Academic Press
ISBN 13 : 0323856802
Total Pages : 762 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Genome Stability by : Igor Kovalchuk

Download or read book Genome Stability written by Igor Kovalchuk and published by Academic Press. This book was released on 2021-07-17 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome Stability: From Virus to Human Application, Second Edition, a volume in the Translational Epigenetics series, explores how various species maintain genome stability and genome diversification in response to environmental factors. Here, across thirty-eight chapters, leading researchers provide a deep analysis of genome stability in DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, examining how epigenetic factors contribute to genome stability and how these species pass memories of encounters to progeny. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, and genome stability in response to aging. This second edition has been fully revised to address evolving research trends, including CRISPRs/Cas9 genome editing; conventional versus transgenic genome instability; breeding and genetic diseases associated with abnormal DNA repair; RNA and extrachromosomal DNA; cloning, stem cells, and embryo development; programmed genome instability; and conserved and divergent features of repair. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability. A deep analysis of genome stability research from various kingdoms, including epigenetics and transgenerational effects Provides comprehensive coverage of mechanisms utilized by different organisms to maintain genomic stability Contains applications of genome instability research and outcomes for human disease Features all-new chapters on evolving areas of genome stability research, including CRISPRs/Cas9 genome editing, RNA and extrachromosomal DNA, programmed genome instability, and conserved and divergent features of repair

The Minders

Author : John Marrs
Publisher : Penguin
ISBN 13 : 0593334728
Total Pages : 418 pages
Book Rating : 4.5/5 (933 download)

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Book Synopsis The Minders by : John Marrs

Download or read book The Minders written by John Marrs and published by Penguin. This book was released on 2021-02-16 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this electrifying near-future thriller, five strangers guard government secrets, but only four can be trusted. In the 21st century, information is king. But computers can be hacked and files can be broken into - so a unique government initiative has been born. Five ordinary people have been selected to become Minders - the latest weapon in thwarting cyberterrorism. Transformed by a revolutionary medical procedure, the country's most classified information has been taken offline and turned into genetic code implanted inside their heads. Together, the five know every secret - the truth behind every government lie, conspiracy theory and cover up. In return, they're given the chance to leave their problems behind and a blank slate to start their lives anew. But not everyone should be trusted, especially when they each have secrets of their own they'll do anything to protect...

Translational Medicine

Author : Joy A. Cavagnaro
Publisher : CRC Press
ISBN 13 : 1000471853
Total Pages : 952 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Translational Medicine by : Joy A. Cavagnaro

Download or read book Translational Medicine written by Joy A. Cavagnaro and published by CRC Press. This book was released on 2021-11-26 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.

Stem Cell Genetics for Biomedical Research

Author : Raul Delgado-Morales
Publisher : Springer
ISBN 13 : 331990695X
Total Pages : 426 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Stem Cell Genetics for Biomedical Research by : Raul Delgado-Morales

Download or read book Stem Cell Genetics for Biomedical Research written by Raul Delgado-Morales and published by Springer. This book was released on 2018-06-27 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer’s disease, cancer, and heart disorders, the book summarizes the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. Since Professor Shinya Yamanaka described it, 10 years ago in his seminal paper, that somatic cells could be reprogrammed to inducible stem cells (iPSC) just by expressing four transcription factors, the field of has exploded, especially its applications in biomedical research.

The CRISPR/Cas Tool Kit for Genome Editing

Author : Aftab Ahmad
Publisher : Springer Nature
ISBN 13 : 981166305X
Total Pages : 342 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis The CRISPR/Cas Tool Kit for Genome Editing by : Aftab Ahmad

Download or read book The CRISPR/Cas Tool Kit for Genome Editing written by Aftab Ahmad and published by Springer Nature. This book was released on 2022-01-01 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses CRISPR/Cas- one of the most powerful tools available to scientists for genome editing. CRISPR/Cas is not only a genome editing tool, but researchers have also engineered it for gene regulation, genome imaging, base editing and epigenome regulations. This book describes the entire toolkit for CRISPR/Cas. The opening section gives an introduction to the technique and compares it with other genome editing tools. Further section gives a historical perspective of the tool, along with its detailed classification. The next chapters describe bioinformatic tools in CRISPR/Cas, and delivery methods for CRISPR/Cas. The book also discusses about the applications of CRISPR/Cas beyond genome editing and use of CRISPR for rewriting genetic codes. The book dedicates a section to the use of CRISPR in plants. The book culminates with a chapter on the current status, challenges and shortcomings of the CRISPR/Cas genome editing tool. The book would be highly interesting to students and researchers in molecular biology, biochemistry, biotechnology, food science, agriculture and plant sciences.

Cell adhesion molecules in neural development and disease

Author : Zsolt Lele
Publisher : Frontiers Media SA
ISBN 13 : 2832514219
Total Pages : 143 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Cell adhesion molecules in neural development and disease by : Zsolt Lele

Download or read book Cell adhesion molecules in neural development and disease written by Zsolt Lele and published by Frontiers Media SA. This book was released on 2023-02-09 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Optimal High-Throughput Screening

Author : Xiaohua Douglas Zhang
Publisher : Cambridge University Press
ISBN 13 : 1139498371
Total Pages : 223 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Optimal High-Throughput Screening by : Xiaohua Douglas Zhang

Download or read book Optimal High-Throughput Screening written by Xiaohua Douglas Zhang and published by Cambridge University Press. This book was released on 2011-02-21 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise, self-contained and cohesive book focuses on commonly used and recently developed methods for designing and analyzing high-throughput screening (HTS) experiments from a statistically sound basis. Combining ideas from biology, computing and statistics, the author explains experimental designs and analytic methods that are amenable to rigorous analysis and interpretation of RNAi HTS experiments. The opening chapters are carefully presented to be accessible both to biologists with training only in basic statistics and to computational scientists and statisticians with basic biological knowledge. Biologists will see how new experiment designs and rudimentary data-handling strategies for RNAi HTS experiments can improve their results, whereas analysts will learn how to apply recently developed statistical methods to interpret HTS experiments.

Next-Generation Plant Breeding Approaches for Stress Resilience in Cereal Crops

Author : Mallana Gowdra Mallikarjuna
Publisher : Springer Nature
ISBN 13 : 9811914451
Total Pages : 507 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Next-Generation Plant Breeding Approaches for Stress Resilience in Cereal Crops by : Mallana Gowdra Mallikarjuna

Download or read book Next-Generation Plant Breeding Approaches for Stress Resilience in Cereal Crops written by Mallana Gowdra Mallikarjuna and published by Springer Nature. This book was released on 2022-09-15 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book highlights the gravity and efficacy of next-generation breeding tools for the enhancement of stress-resilience in cereals, especially in the context of climate change, pests, diseases, and abiotic stresses. The content of the book helps in understanding the application of emerging genetic concepts and neoteric genomic approaches in cereal breeding. It collates all the latest information about enhancing the stress resilience in cereal crops for overcoming food security issues. Cereals have predominantly been used as a staple food since time immemorial and contribute more than 50% of the caloric requirement of the global population. However, in cereals, the yield losses due to various stresses are very high, considering the crop growth stage and stress sensitivity. Therefore, to feed and nourish the generations in the era of climate change, it is imperative to develop stress-resilient cereal cultivars. This book explores newly developed next-generation breeding tools, viz., genome-wide association studies, genomic prediction, genome editing, and accelerated generation advancement methodologies, which revealed promising outcomes by enhancing the stress resilience in cereals with yield potential. This book is useful for postgraduate students specializing in plant breeding, plant stress physiology, plant genomics, agriculture, and agronomy. It is of immense value to scientific community involved in teaching, research, and extension activities related to cereal cultivation.

Bioinformatics

Author : Mahmood A. Mahdavi
Publisher : BoD – Books on Demand
ISBN 13 : 9533072822
Total Pages : 740 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Bioinformatics by : Mahmood A. Mahdavi

Download or read book Bioinformatics written by Mahmood A. Mahdavi and published by BoD – Books on Demand. This book was released on 2011-11-02 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics - Trends and Methodologies is a collection of different views on most recent topics and basic concepts in bioinformatics. This book suits young researchers who seek basic fundamentals of bioinformatic skills such as data mining, data integration, sequence analysis and gene expression analysis as well as scientists who are interested in current research in computational biology and bioinformatics including next generation sequencing, transcriptional analysis and drug design. Because of the rapid development of new technologies in molecular biology, new bioinformatic techniques emerge accordingly to keep the pace of in silico development of life science. This book focuses partly on such new techniques and their applications in biomedical science. These techniques maybe useful in identification of some diseases and cellular disorders and narrow down the number of experiments required for medical diagnostic.

Comprehensive Medicinal Chemistry III

Author :
Publisher : Elsevier
ISBN 13 : 0128032014
Total Pages : 4609 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Comprehensive Medicinal Chemistry III by :

Download or read book Comprehensive Medicinal Chemistry III written by and published by Elsevier. This book was released on 2017-06-03 with total page 4609 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs

Nanomedical Drug Delivery for Neurodegenerative Diseases

Author : Awesh K. Yadav
Publisher : Academic Press
ISBN 13 : 0323898017
Total Pages : 284 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Nanomedical Drug Delivery for Neurodegenerative Diseases by : Awesh K. Yadav

Download or read book Nanomedical Drug Delivery for Neurodegenerative Diseases written by Awesh K. Yadav and published by Academic Press. This book was released on 2022-03-10 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedical Drug Delivery for Neurodegenerative Diseases opens the door for promising approaches and advances in the diagnosis and treatment of various neurodegenerative diseases. The contents of the book comprise all the aspects related to the design, synthesis, and application of different nanodrug delivery systems in the treatment of neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases. This book explores how nanoparticulate drug carriers can improve therapeutic efficacy by selecting a suitable design strategy. Nanomedical Drug Delivery for Neurodegenerative Diseases is a valuable resource for graduates, clinical researchers, and other scientists working to minimize the challenges to deliver the drugs and genes in a more efficient and targeted manner for the treatment of neurodegenerative diseases. Includes design, synthesis and applications of drug delivery systems Explores the role of nanotechnology in the diagnosis and treatment of neurodegenerative disorders Reviews applications for the management of Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases Discusses extracellular vesicles and mitochondria-targeted bioactive delivery systems Details how nanocarrier-based delivery is useful to improve efficacy and cure

Nucleic Acids in Medicinal Chemistry and Chemical Biology

Author : Lihe Zhang
Publisher : John Wiley & Sons
ISBN 13 : 1119692784
Total Pages : 564 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Nucleic Acids in Medicinal Chemistry and Chemical Biology by : Lihe Zhang

Download or read book Nucleic Acids in Medicinal Chemistry and Chemical Biology written by Lihe Zhang and published by John Wiley & Sons. This book was released on 2022-12-15 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleic Acids in Medicinal Chemistry and Chemical Biology An up-to-date and comprehensive exploration of nucleic acid medicinal chemistry and its applications In Nucleic Acids in Medicinal Chemistry and Chemical Biology: Drug Development and Clinical Applications, a team of distinguished researchers delivers a comprehensive overview of the chemistry and biology of nucleic acids and their therapeutic applications. The book emphasizes the latest research in the field, including new technologies like CRISPR that create novel possibilities to edit mutated genes at the genomic DNA level and to treat inherited diseases and cancers. The authors explore the application of modified nucleosides and nucleotides in medicinal chemistry, a variety of current topics on nucleic acid chemistry and biology, nucleic acid drugs used to treat disease, and more. They also probe new domains of pharmaceutical research, offering the reader a wealth of new drug discovery opportunities emerging in this dynamic field. Readers will also find: A thorough introduction to the basic terminology and knowledge of the field of nucleic acid medicinal chemistry Comprehensive explorations of the methods used to determine the development of nucleic acid drugs Practical discussions of new technologies, like CRISPR, nanotechnology-based delivery systems, synthetic biology, and DNA-encoded chemical libraries In-depth examinations of the latest, cutting-edge developments in nucleic acid medicinal chemistry Perfect for medicinal and nucleic acid chemists, Nucleic Acids in Medicinal Chemistry and Chemical Biology will also earn a place in the libraries of biochemists, chemical biologists, and pharmaceutical researchers.