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Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 475 Mammalian Bone Marrow Chromosomal Aberration Test
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Book Synopsis Test No. 475: Mammalian Bone Marrow Chromosomal Aberration Test by : OECD
Download or read book Test No. 475: Mammalian Bone Marrow Chromosomal Aberration Test written by OECD and published by OECD Publishing. This book was released on 2014-09-26 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian in vivo chromosome aberration test is used for the detection of structural chromosome aberrations induced by test compounds in bone marrow cells of animals, usually rodents (rats, mice and Chinese hamsters).
Book Synopsis Test No. 475: Mammalian Bone Marrow Chromosome Aberration Test by : OECD
Download or read book Test No. 475: Mammalian Bone Marrow Chromosome Aberration Test written by OECD and published by OECD Publishing. This book was released on 1997-07-21 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian in vivo chromosome aberration test is used for the detection of structural chromosome aberrations induced by test compounds in bone marrow cells of animals, usually rodents (rats, mice and Chinese hamsters). Structural chromosome ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 473: In Vitro Mammalian Chromosomal Aberration Test by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 473: In Vitro Mammalian Chromosomal Aberration Test written by OECD and published by OECD Publishing. This book was released on 2016-07-29 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt: This test identifies agents that cause structural chromosome aberrations in cultured mammalian somatic cells.
Book Synopsis Test No. 483: Mammalian Spermatogonial Chromosomal Aberration Test by : OECD
Download or read book Test No. 483: Mammalian Spermatogonial Chromosomal Aberration Test written by OECD and published by OECD Publishing. This book was released on 2015-07-28 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: This test measures structural chromosomal aberrations (both chromosome- and chromatid-type) in dividing spermatogonial germ cells and is, therefore, expected to be predictive of induction of heritable mutations in these germ cells
Book Synopsis Test No. 474: Mammalian Erythrocyte Micronucleus Test by : OECD
Download or read book Test No. 474: Mammalian Erythrocyte Micronucleus Test written by OECD and published by OECD Publishing. This book was released on 2014-09-26 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian in vivo micronucleus test detects damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone marrow and/or peripheral blood cells of animals.
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 475: Mammalian Bone Marrow Chromosomal Aberration Test by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 475: Mammalian Bone Marrow Chromosomal Aberration Test written by OECD and published by OECD Publishing. This book was released on 2016-07-29 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian in vivo chromosome aberration test is used for the detection of structural chromosome aberrations induced by test compounds in bone marrow cells of animals, usually rodents (rats, mice and Chinese hamsters).
Book Synopsis Test No. 473: In Vitro Mammalian Chromosomal Aberration Test by : OECD
Download or read book Test No. 473: In Vitro Mammalian Chromosomal Aberration Test written by OECD and published by OECD Publishing. This book was released on 2014-09-26 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: This test identifies agents that cause structural chromosome aberrations in cultured mammalian somatic cells.
Book Synopsis Test No. 475: Mammalian Bone Marrow Chromosome Aberration Test by : Organisation for Economic Co-operation and Development
Download or read book Test No. 475: Mammalian Bone Marrow Chromosome Aberration Test written by Organisation for Economic Co-operation and Development and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay written by OECD and published by OECD Publishing. This book was released on 2022-06-30 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vivo erythrocyte Pig-a gene mutation assay (hereafter called the Pig-a assay) which uses an endogenous mammalian gene, the phosphatidylinositol glycan class A gene (Pig-a), as a reporter of somatic-cell gene mutation. In vivo gene mutation tests, such as the Pig-a assay, are especially relevant for assessing mutagenicity because physiological factors, such as absorption of the test chemical from the site of exposure, distribution of the test chemical throughout the test system via systemic circulation, and in vivo metabolism and DNA repair processes, all contribute to the mutagenic responses.
Book Synopsis Test No. 473: In vitro Mammalian Chromosome Aberration Test by : OECD
Download or read book Test No. 473: In vitro Mammalian Chromosome Aberration Test written by OECD and published by OECD Publishing. This book was released on 1997-07-21 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the in vitro chromosome aberration test is to identify agents that cause structural chromosome aberrations in cultured mammalian somatic cells. Structural aberrations may be of two types: chromosome or chromatid. The in vitro ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 485: Genetic toxicology, Mouse Heritable Translocation Assay by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 485: Genetic toxicology, Mouse Heritable Translocation Assay written by OECD and published by OECD Publishing. This book was released on 1986-10-23 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mouse heritable translocation test detects structural and numerical chromosome changes in mammalian germ cells as recovered in first generation progeny. The types of chromosome changes detected in this test system are reciprocal translocations ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 478: Rodent Dominant Lethal Test by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 478: Rodent Dominant Lethal Test written by OECD and published by OECD Publishing. This book was released on 2016-07-29 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the Dominant lethal (DL) test is to investigate whether chemical agents produce mutations resulting from chromosomal aberrations in germ cells.
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes written by OECD and published by OECD Publishing. This book was released on 2016-07-29 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in vitro mammalian cell gene mutation test can be used to detect gene mutations induced by chemical substances. In this test, the used genetic endpoints measure mutation at hypoxanthine-guanine phosphoribosyl transferase (HPRT), and at a transgene of xanthineguanine phosphoribosyl transferase...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 479: Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 479: Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells written by OECD and published by OECD Publishing. This book was released on 1986-10-23 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sister chromatid exchange (SCE) assay is a short-term test for the detection of reciprocal exchanges of DNA between two sister chromatids of a duplicating chromosome. Detection of SCEs requires some means of differentially labeling sister ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 482: Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells in vitro by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 482: Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells in vitro written by OECD and published by OECD Publishing. This book was released on 1986-10-23 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline for Unscheduled DNA Synthesis (UDS) in mammalian cells in vitro describes procedures utilizing primary cultures, human lymphocytes or established cell lines, to detect DNA repair synthesis after excision and removal of a stretch ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 490: In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 490: In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene written by OECD and published by OECD Publishing. This book was released on 2016-07-29 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: This TG includes two distinct in vitro mammalian gene mutation assays requiring two specific tk heterozygous cells lines: L5178Y tk+/-3.7.2C cells for the mouse lymphoma assay (MLA) and TK6 tk+/- cells for the TK6 assay.