OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents

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Publisher : OECD Publishing
ISBN 13 : 9264070702
Total Pages : 16 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been obtained from acute or repeated dose ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents

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Publisher : OECD Publishing
ISBN 13 : 9264070729
Total Pages : 9 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents written by OECD and published by OECD Publishing. This book was released on 1998-09-21 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents

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Publisher : OECD Publishing
ISBN 13 : 9264070680
Total Pages : 13 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents written by OECD and published by OECD Publishing. This book was released on 2008-10-16 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The method is based on the repeated oral administration of the substance of interest during one limited period (one dose level ...

OECD Guidelines for Testing of Chemicals

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Publisher : Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
ISBN 13 : 9789264122215
Total Pages : pages
Book Rating : 4.1/5 (222 download)

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Book Synopsis OECD Guidelines for Testing of Chemicals by : Organisation for Economic Co-operation and Development

Download or read book OECD Guidelines for Testing of Chemicals written by Organisation for Economic Co-operation and Development and published by Organisation for Economic Co-operation and Development ; [Montréal : Renouf]. This book was released on 1981 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies

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Publisher : OECD Publishing
ISBN 13 : 9264071202
Total Pages : 18 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 424: Neurotoxicity Study in Rodents

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Publisher : OECD Publishing
ISBN 13 : 9264071024
Total Pages : 15 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 424: Neurotoxicity Study in Rodents by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 424: Neurotoxicity Study in Rodents written by OECD and published by OECD Publishing. This book was released on 1997-07-21 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline has been designed to obtain the information necessary to confirm or to further characterise the potential neurotoxicity of chemicals in adult animals. This Test Guideline is designed for use with the rat. It specifically ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure

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Publisher : OECD Publishing
ISBN 13 : 926407094X
Total Pages : 14 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure written by OECD and published by OECD Publishing. This book was released on 2002-02-08 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method

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Publisher : OECD Publishing
ISBN 13 : 9264071008
Total Pages : 14 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method written by OECD and published by OECD Publishing. This book was released on 2002-02-08 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay

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Publisher : OECD Publishing
ISBN 13 : 9264366067
Total Pages : 37 pages
Book Rating : 4.2/5 (643 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay written by OECD and published by OECD Publishing. This book was released on 2022-06-30 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vivo erythrocyte Pig-a gene mutation assay (hereafter called the Pig-a assay) which uses an endogenous mammalian gene, the phosphatidylinositol glycan class A gene (Pig-a), as a reporter of somatic-cell gene mutation. In vivo gene mutation tests, such as the Pig-a assay, are especially relevant for assessing mutagenicity because physiological factors, such as absorption of the test chemical from the site of exposure, distribution of the test chemical throughout the test system via systemic circulation, and in vivo metabolism and DNA repair processes, all contribute to the mutagenic responses.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study

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Publisher : OECD Publishing
ISBN 13 : 9264070761
Total Pages : 9 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study written by OECD and published by OECD Publishing. This book was released on 1981-05-12 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance. It may be carried out after initial information obtained by acute testing. This method is composed of the main test and the limit ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 410: Repeated Dose Dermal Toxicity: 21/28-day Study

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Publisher : OECD Publishing
ISBN 13 : 9264070745
Total Pages : 8 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 410: Repeated Dose Dermal Toxicity: 21/28-day Study by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 410: Repeated Dose Dermal Toxicity: 21/28-day Study written by OECD and published by OECD Publishing. This book was released on 1981-05-12 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study relates to the analysis, via dermal application, of the health hazard of solid or liquid test substance. This method is composed of two tests: the main test and the limit test. This Test Guideline is intended for use with the adult rat ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity

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Publisher : OECD Publishing
ISBN 13 : 9264070583
Total Pages : 13 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity written by OECD and published by OECD Publishing. This book was released on 2017-10-09 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from a short-term exposure to solid or liquid test substance by the dermal route. This Test Guideline is intended primarily for use with rodents (rat, rabbit or guinea pig may be ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 419: Delayed Neurotoxicity of Organophosphorus Substances: 28-day Repeated Dose Study

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Publisher : OECD Publishing
ISBN 13 : 9264070923
Total Pages : 7 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 419: Delayed Neurotoxicity of Organophosphorus Substances: 28-day Repeated Dose Study by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 419: Delayed Neurotoxicity of Organophosphorus Substances: 28-day Repeated Dose Study written by OECD and published by OECD Publishing. This book was released on 1995-07-27 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline is used in the assessment and evaluation of the toxic effects of organophosporus substances. Daily doses of the test substance are administered orally (preferably by gavage or administration of gelatin capsules) to domestic ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies

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Publisher : OECD Publishing
ISBN 13 : 9264071229
Total Pages : 20 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 413: Subchronic Inhalation Toxicity: 90-day Study

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Publisher : OECD Publishing
ISBN 13 : 926407080X
Total Pages : 23 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 413: Subchronic Inhalation Toxicity: 90-day Study by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 413: Subchronic Inhalation Toxicity: 90-day Study written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised Test Guideline has been designed to fully characterize test article toxicity by the inhalation route for a subchronic duration (90 days), and to provide robust data for quantitative inhalation risk assessments. Groups of 10 male and 10 ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test

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Publisher : OECD Publishing
ISBN 13 : 9264071482
Total Pages : 4 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test written by OECD and published by OECD Publishing. This book was released on 1986-10-23 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mouse spot test detects presumed somatic mutations in fetal cells following transplacental absorption of the test substance. This is an in vivo test in mice in which developing embryos are exposed to a chemical (solid, liquid, vapour or ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study

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Publisher : OECD Publishing
ISBN 13 : 9264070826
Total Pages : 14 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...