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Oecd Guidelines For The Testing Of Chemicals Section 4 Health Effects Test No 487 In Vitro Mammalian Cell Micronucleus Test
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Book Synopsis Test No. 487: In Vitro Mammalian Cell Micronucleus Test by : OECD
Download or read book Test No. 487: In Vitro Mammalian Cell Micronucleus Test written by OECD and published by OECD Publishing. This book was released on 2010-07-23 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in vitro micronucleus test is a genotoxicity test for the detection of micronuclei in the cytoplasm of interphase cells. Micronuclei may originate from acentric chromosome fragments (i.e. lacking a centromere), or whole chromosomes that are ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 487: In Vitro Mammalian Cell Micronucleus Test by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 487: In Vitro Mammalian Cell Micronucleus Test written by OECD and published by OECD Publishing. This book was released on 2023-07-04 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in vitro micronucleus test is a genotoxicity test for the detection of micronuclei in the cytoplasm of interphase cells.
Book Synopsis Test No. 474: Mammalian Erythrocyte Micronucleus Test by : OECD
Download or read book Test No. 474: Mammalian Erythrocyte Micronucleus Test written by OECD and published by OECD Publishing. This book was released on 2014-09-26 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian in vivo micronucleus test detects damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone marrow and/or peripheral blood cells of animals.
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 482: Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells in vitro by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 482: Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells in vitro written by OECD and published by OECD Publishing. This book was released on 1986-10-23 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline for Unscheduled DNA Synthesis (UDS) in mammalian cells in vitro describes procedures utilizing primary cultures, human lymphocytes or established cell lines, to detect DNA repair synthesis after excision and removal of a stretch ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 479: Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 479: Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells written by OECD and published by OECD Publishing. This book was released on 1986-10-23 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sister chromatid exchange (SCE) assay is a short-term test for the detection of reciprocal exchanges of DNA between two sister chromatids of a duplicating chromosome. Detection of SCEs requires some means of differentially labeling sister ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 481: Genetic Toxicology: Saacharomyces cerevisiae, Miotic Recombination Assay by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 481: Genetic Toxicology: Saacharomyces cerevisiae, Miotic Recombination Assay written by OECD and published by OECD Publishing. This book was released on 1986-10-23 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: This assay may be used to measure mitotic recombination (gene conversion or crossingover) in yeast, a eukaryotic micro-organism. Crossing-over is generally assayed by the production of recessive homozygous colonies or sectors produced in a ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study written by OECD and published by OECD Publishing. This book was released on 1981-05-12 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance. It may be carried out after initial information obtained by acute testing. This method is composed of the main test and the limit ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 415: One-Generation Reproduction Toxicity Study by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 415: One-Generation Reproduction Toxicity Study written by OECD and published by OECD Publishing. This book was released on 2019-03-01 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline for reproduction testing is designed to provide general information concerning the effects of a test substance (Solid, liquid, gas or vapour) on male and female reproductive performance. The test substance is administered orally ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 477: Genetic Toxicology: Sex-Linked Recessive Lethal Test in Drosophila melanogaster by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 477: Genetic Toxicology: Sex-Linked Recessive Lethal Test in Drosophila melanogaster written by OECD and published by OECD Publishing. This book was released on 1984-04-04 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mutations in the X-chromosome of Drosophila melanogaster are phenotypically expressed in males carrying the mutant gene. When the mutation is lethal in the hemizygous condition, its presence is inferred from the absence of one class of male ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4: Health Effects Test No. 436: Acute Inhalation Toxicity – Acute Toxic Class Method by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4: Health Effects Test No. 436: Acute Inhalation Toxicity – Acute Toxic Class Method written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: The method described by this Test Guideline provides information that allows hazard assessment for short-term exposure to a test article by inhalation, and allows the substance to be classified according to the Globally Harmonized System of ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 486: Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 486: Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo written by OECD and published by OECD Publishing. This book was released on 1997-07-21 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo is to identify substances that induce DNA repair after excision and removal of a stretch of DNA containing a region of damage induced by chemical substances ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method written by OECD and published by OECD Publishing. This book was released on 2002-02-08 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 484: Genetic Toxicology: Mouse Spot Test written by OECD and published by OECD Publishing. This book was released on 1986-10-23 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mouse spot test detects presumed somatic mutations in fetal cells following transplacental absorption of the test substance. This is an in vivo test in mice in which developing embryos are exposed to a chemical (solid, liquid, vapour or ...
Book Synopsis OECD Guidelines for the Testing of Chemicals / Section 4: Health Effects Test No. 479: Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals / Section 4: Health Effects Test No. 479: Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells written by OECD and published by OECD Publishing. This book was released on 1986-10-23 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sister chromatid exchange (SCE) assay is a short-term test for the detection of reciprocal exchanges of DNA between two sister chromatids of a duplicating chromosome. Detection of SCEs requires some means of differentially labeling sister ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 413: Subchronic Inhalation Toxicity: 90-day Study by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 413: Subchronic Inhalation Toxicity: 90-day Study written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised Test Guideline has been designed to fully characterize test article toxicity by the inhalation route for a subchronic duration (90 days), and to provide robust data for quantitative inhalation risk assessments. Groups of 10 male and 10 ...
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 427: Skin Absorption: In Vivo Method by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 427: Skin Absorption: In Vivo Method written by OECD and published by OECD Publishing. This book was released on 2004-11-23 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in vivo percutaneous absorption study set out in this Test Guideline provides the linkage necessary to extrapolate from oral studies when making safety assessments following dermal exposure. The in vivo method, described in this guideline ...
