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Oecd Guidelines For The Testing Of Chemicals Oecd Series On Testing And Assessment Guidance Document On The Use Of Multimedia Models For Estimating Overall Environmental Persistance And Long Range Transport
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Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on the Use of Multimedia Models for Estimating Overall Environmental Persistance and Long-Range Transport by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on the Use of Multimedia Models for Estimating Overall Environmental Persistance and Long-Range Transport written by OECD and published by OECD Publishing. This book was released on 2004-11-01 with total page 83 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Guidance Document concerns using multimedia models, i.e. generic evaluative models that can calculate overall environmental persistence (Pov) and potential for long-range transport (LTRP) covering multiple compartments such as air, water, sediment and soil.
Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on Reporting Summary Information on Environmental, Occupational and Consumer Exposure by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on Reporting Summary Information on Environmental, Occupational and Consumer Exposure written by OECD and published by OECD Publishing. This book was released on 2004-11-01 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document contains guidance for using the summary exposure information reporting formats, which were developed by the OECD Ad Hoc Group on Reporting Summary Exposure Information.
Book Synopsis OECD Series on Testing and Assessment The Guidance Document for Using the OECD (Q)SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals by : OECD
Download or read book OECD Series on Testing and Assessment The Guidance Document for Using the OECD (Q)SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document provides guidance on how to use the OECD (Q)SAR Application Toolbox to build chemical categories according to the OECD Guidance on Grouping of Chemicals. It is part of an overall effort to provide guidance on the use of the (Q)SAR Application Toolbox.
Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Report of the OECD/UNEP Workshop on the Use of Multimedia Models for Estimating Overall Environmental Persistence and Long Range Transport in the Context of PBTS/POPS Assessment by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Report of the OECD/UNEP Workshop on the Use of Multimedia Models for Estimating Overall Environmental Persistence and Long Range Transport in the Context of PBTS/POPS Assessment written by OECD and published by OECD Publishing. This book was released on 2002-12-12 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document contains the report from the OECD/UNEP Workshop on the Use of Multimedia Models for Estimating Overall Persistence and Long-range Transport in the Context of PBTs/POPs Assessment, held on 29-31 October 2001 in Ottawa, Canada, together ...
Book Synopsis OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition by : OECD
Download or read book OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.
Book Synopsis Principles of Toxicology Testing, Second Edition by : Frank A Barile
Download or read book Principles of Toxicology Testing, Second Edition written by Frank A Barile and published by CRC Press. This book was released on 2013-04-02 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, including absorption, distribution, metabolism, and elimination of toxins, including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition, the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing, such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies, including dermal, ocular, and reproductive toxicity testing. In addition, mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity, target organ toxicity, and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications, the concepts of standardization and validation of in vitro techniques (especially large, organized validation efforts currently supported by US and EU regulatory agencies), and the theories supporting the development of in vitro methodologies. This second edition is a must-read for undergraduate and graduate toxicology students. Industrial and academic research centers will also find the text useful for establishing a toxicology testing laboratory.
Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies written by OECD and published by OECD Publishing. This book was released on 2002-12-12 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: These Guidance Notes outline core concepts in order to obviate the need to consult large numbers of text books, while still pointing the reader to sources of more detailed or specific information.
Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances written by OECD and published by OECD Publishing. This book was released on 2004-11-01 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals.
Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document for the Conduct of Skin Absorption Studies by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document for the Conduct of Skin Absorption Studies written by OECD and published by OECD Publishing. This book was released on 2004-11-01 with total page 31 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guidance document has been prepared to support technical aspects of the OECD skin absorption test guidelines. In particular is discusses the various aspects of in vivo vs. in vitro testing.
Book Synopsis OECD Series on Testing and Assessment Guidance on Grouping of Chemicals by : OECD
Download or read book OECD Series on Testing and Assessment Guidance on Grouping of Chemicals written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guidance document provides guidance for assessing the hazards of chemical substances while gaining efficiencies and improving animal welfare. The approach described in this guidance document is to consider closely related chemicals as a group, or category, rather than as individual chemicals.
Book Synopsis OECD Environmental Strategy 2004 Review of Progress by : OECD
Download or read book OECD Environmental Strategy 2004 Review of Progress written by OECD and published by OECD Publishing. This book was released on 2004-04-20 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report assesses the progress that OECD countries have made in implementing objectives set out in an Environmentl Strategy adopted in 2001, as well as in applying the 71 national actions they agreed as part of that Strategy.
Book Synopsis Guidance Document on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption by : OECD
Download or read book Guidance Document on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document is a tool to support regulatory authorities’ decisions on the hazard of specific chemicals when they receive test results from a Test Guideline (TG) or draft TG for the screening/testing of chemicals for endocrine disrupting properties.
Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances written by OECD and published by OECD Publishing. This book was released on 2004-11-01 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Detailed Review Paper (DRP) provides the current state-of-the-knowledge in the area of amphibian metamorphosis with the view to use amphibian metamorphosis as a model for the detection of chemicals affecting the thyroid axis in vertebrates.
Book Synopsis Persistent, Bioaccumulative, and Toxic (PBT) Chemicals by : Adam D. K. Abelkop
Download or read book Persistent, Bioaccumulative, and Toxic (PBT) Chemicals written by Adam D. K. Abelkop and published by CRC Press. This book was released on 2018-10-08 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developed from the efforts of a multiyear, international project examining how persistent, bioaccumulative, and toxic (PBT) chemicals are evaluated and managed, Persistent, Bioaccumulative, and Toxic (PBT) Chemicals: Technical Aspects, Policies, and Practices focuses on improving the processes that govern PBTs. Incorporating science and policy literature—as well as interviews and panel discussions featuring experts from around the world—this book provides you with an international perspective of PBT policies (centering on Europe, Asia, and North America), and reveals major findings and recommendations for improving PBT science, laws, and policies. It includes case studies of specific chemicals, provides an introduction to the overall subject of toxic chemicals, and weighs in on science and policy expansion for PBTs. It also provides summary tables of important PBTs, and discussions on the number of PBTs in commerce, weight of evidence approaches, market deselection, and international management. The text: Assesses the history, current practice, and future of PBT management Considers the roles scientific data, modeling, and conventions play in identifying and regulating PBTs Explores the number of PBTs in commerce and the growing role of weight of evidence (WOE) in the making of PBT determinations Identifies issues that are likely to come up in WOE judgments Examines international, national, subnational, and regional PBT policies Includes a comprehensive and easy-to-understand analysis of PBT science and policy This book reviews the current science, policies, and practices surrounding the regulation of PBTs. It also provides relevant research, recommendations, and suggestions for improving the management and oversight of PBTs.
Author :P. Nicolopoulou-Stamati Publisher :Springer Science & Business Media ISBN 13 :1402048319 Total Pages :492 pages Book Rating :4.4/5 (2 download)
Book Synopsis Congenital Diseases and the Environment by : P. Nicolopoulou-Stamati
Download or read book Congenital Diseases and the Environment written by P. Nicolopoulou-Stamati and published by Springer Science & Business Media. This book was released on 2007-06-10 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores some further concepts that have arisen from more recent perceptions of environmental effects and their possible interactions with living systems. The book is written by international experts and numerous case studies are given. Discussion and presentation of old and novel ideas is targeted at developing a more holistic and united perception of the interaction between congenital diseases and the environment.
Book Synopsis OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on the Use of Multimedia Models for Estimating Overall Environmental Persistance and Long-Range Transport by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on the Use of Multimedia Models for Estimating Overall Environmental Persistance and Long-Range Transport written by OECD and published by OECD Publishing. This book was released on 2004-11-01 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Guidance Document is addressed to those who are involved in risk assessment and management of chemicals called POPs (persistent organic pollutants) or PBTs (persistent and bio-accumulating toxics). It is about using multimedia models, i.e. generic evaluative models that can calculate overall environmental persistence (Pov) and potential for long-range transport (LTRP) covering multiple compartments such as air, water, sediment and soil: what models you can use to identify and characterize POPs/PBTs, what data to use, and how to use model calculations.
Book Synopsis Models in Environmental Regulatory Decision Making by : National Research Council
Download or read book Models in Environmental Regulatory Decision Making written by National Research Council and published by National Academies Press. This book was released on 2007-08-25 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many regulations issued by the U.S. Environmental Protection Agency (EPA) are based on the results of computer models. Models help EPA explain environmental phenomena in settings where direct observations are limited or unavailable, and anticipate the effects of agency policies on the environment, human health and the economy. Given the critical role played by models, the EPA asked the National Research Council to assess scientific issues related to the agency's selection and use of models in its decisions. The book recommends a series of guidelines and principles for improving agency models and decision-making processes. The centerpiece of the book's recommended vision is a life-cycle approach to model evaluation which includes peer review, corroboration of results, and other activities. This will enhance the agency's ability to respond to requirements from a 2001 law on information quality and improve policy development and implementation.
