Obesity Diabetes And Inflammation

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Obesity, Diabetes and Inflammation

Author : Dimiter Avtanski
Publisher : Springer Nature
ISBN 13 : 3031397215
Total Pages : 236 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Obesity, Diabetes and Inflammation by : Dimiter Avtanski

Download or read book Obesity, Diabetes and Inflammation written by Dimiter Avtanski and published by Springer Nature. This book was released on 2023-09-26 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a worldwide epidemic that affects half a billion people. It has been estimated that, if current trends continue, by 2050, 60% of men and 50% of women worldwide will be obese. Hypertrophy and hyperplasia of white adipose tissue caused by overweight and obesity lead to a chronic inflammatory state, which results in impaired insulin sensitivity and the development of diabetes. Currently, the number of people affected by diabetes globally exceeds 400 million (rising more rapidly in low- and middle-income countries). In 2019, diabetes was the ninth leading cause of mortality, with an estimated 1.5 million direct deaths. This book provides a comprehensive overview of the relationship between inflammation, obesity, and diabetes. It focuses on the pathogenesis and biological mechanisms of obesity, the interaction between adipose tissue and the immune system, the role of genetic and environmental factors, the progression of cardiovascular complications, and the association of obesity and inflammation with type 1 and type 2 diabetes, as well as gestational diabetes. This volume also includes practical recommendations for preventing and managing these conditions using both lifestyle modifications and pharmacological interventions. Written by experts in the field, Obesity, Diabetes and Inflammation: Molecular Mechanisms and Clinical Management addresses the role of inflammation in both obesity and diabetes, its effect on vascular and non-vascular pathologies, oxidative stress, genetics, and epigenetics. This text aims to be a valuable resource for researchers, clinicians, and students of medicine at all levels.

Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome

Author : Helmut Sies
Publisher : CRC Press
ISBN 13 : 142004379X
Total Pages : 346 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome by : Helmut Sies

Download or read book Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome written by Helmut Sies and published by CRC Press. This book was released on 2007-07-27 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Characterized by obesity, insulin resistance, dyslipidemia, and hypertension, metabolic syndrome is associated with the risks of type 2 diabetes mellitus and cardiovascular disease. Obesity, which increases the incidence of atherosclerotic cardiovascular disease and subsequently leads to increased stress and inflammation, appears to play a central

Obesity-induced inflammation and insulin resistance

Author : Tsuguhito Ota
Publisher : Frontiers Media SA
ISBN 13 : 2889194280
Total Pages : 121 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Obesity-induced inflammation and insulin resistance by : Tsuguhito Ota

Download or read book Obesity-induced inflammation and insulin resistance written by Tsuguhito Ota and published by Frontiers Media SA. This book was released on 2015-03-26 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune response and metabolic regulation are highly integrated and this interface maintains a central homeostatic system, dysfunction of which can cause obesity-associated metabolic disorder such as type 2 diabetes, fatty liver disease and cardiovascular disease. Insulin resistance is an underlying basis for the pathogenesis of these metabolic diseases. Overnutrition or obesity activates the innate immune system with subsequent recruitment of immune cells such as macrophages and T cells, which contributes to the development of insulin resistance. In particular, a significant advance in our understanding of obesity-associated inflammation and insulin resistance has been recognition of the critical role of adipose tissue macrophages (ATMs). ATMs are a prominent source of proinflammatory cytokines, such as TNF-a and IL-6, that can block insulin action in adipose tissue, skeletal muscle, and liver autocrine/paracrine signaling and cause systemic insulin resistance via endocrine signaling, providing a potential link between inflammation and insulin resistance. All articles in this topic highlight the interconnection between obesity, inflammation, and insulin resistance in all its diversity to the mechanisms of obesity-induced inflammation and role of immune system in the pathogenesis of insulin resistance and diabetes.

Meta-Inflammation and Obesity

Author : Asija Začiragić
Publisher : Bentham Science Publishers
ISBN 13 : 9811479631
Total Pages : 224 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Meta-Inflammation and Obesity by : Asija Začiragić

Download or read book Meta-Inflammation and Obesity written by Asija Začiragić and published by Bentham Science Publishers. This book was released on 2020-10-29 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades, scientific efforts have been made to understand obesity and related diseases such as type 2 diabetes and neurodegeneration, and their link with meta-inflammation. Adipose tissue is, at present, viewed as an endocrine organ with important biological effects on metabolism and inflammation, with a possible role in the pathogenesis of obesity-associated metabolic and inflammatory diseases. Chronic systemic low-grade inflammation has gained significant attention as the key player in the pathophysiology of obesity- and aging-associated diseases. Keeping view of this trend, Meta-Inflammation and Obesity offers readers state-of-the-art knowledge on this subject. Chapters cover special topics such as gender differences in obesity-related type 2 diabetes as the consequence of inflammatory response, insights into metabolic changes caused by excessive adipose tissue (which lead to abnormal brain metabolism, neuroinflammation, cognitive decline, development of type 3 diabetes), and the importance of inflammaging in the aging process. Graduate, postgraduate and Ph. D. candidates in medicine, pharmacy, and students of applied medicine, health care professionals as well as scientists involved in adipose tissue research, meta-inflammation analysis, obesity-related medical specialties will find this book a useful reference on the link between inflammation and obesity.

ABC of Obesity

Author : Naveed Sattar
Publisher : John Wiley & Sons
ISBN 13 : 1444312707
Total Pages : 64 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis ABC of Obesity by : Naveed Sattar

Download or read book ABC of Obesity written by Naveed Sattar and published by John Wiley & Sons. This book was released on 2009-04-08 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a hugely expensive and increasing problem worldwide,leading to disability, reproductive problems, depression andaccelerated metabolic and vascular diseases in a large proportionof men, women and children. The ABC of Obesity is a newguide which will aid its effective management, addressing issuessuch as dieting, exercise, self esteem, drug treatment and surgery.Recent evidence is used to highlight frequent problems, successfultreatment options, and the most common causes. Written by leading experts, this is a widely accessible text andan indispensable guide for all general practitioners, juniordoctors, nurses, and other healthcare professionals who areinvolved in the treatment and research of this commoncondition.

Obesity and Diabetes: Implications for Brain-Immunometabolism

Author : Joana M. Gaspar
Publisher : Frontiers Media SA
ISBN 13 : 2889635856
Total Pages : 204 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Obesity and Diabetes: Implications for Brain-Immunometabolism by : Joana M. Gaspar

Download or read book Obesity and Diabetes: Implications for Brain-Immunometabolism written by Joana M. Gaspar and published by Frontiers Media SA. This book was released on 2020-03-16 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Adipose Tissue and Inflammation

Author : Atif B. Awad
Publisher : CRC Press
ISBN 13 : 142009131X
Total Pages : 318 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Adipose Tissue and Inflammation by : Atif B. Awad

Download or read book Adipose Tissue and Inflammation written by Atif B. Awad and published by CRC Press. This book was released on 2009-10-08 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Obesity Association identifies obesity's link to numerous medical conditions, including hypertension, type 2 diabetes, cardiovascular disease, several cancers, and a host of inflammatory disorders. Evidence indicates that inflammation has more than a corollary relation with obesity; that in fact, obesity itself manifests a low-grade, m

The Low-Fat Lie

Author : Glen D. Lawrence
Publisher : Universal-Publishers
ISBN 13 : 1627342788
Total Pages : 312 pages
Book Rating : 4.6/5 (273 download)

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Book Synopsis The Low-Fat Lie by : Glen D. Lawrence

Download or read book The Low-Fat Lie written by Glen D. Lawrence and published by Universal-Publishers. This book was released on 2019-11-15 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advice to consume less fat "especially saturated fat" had a profound, adverse impact on public health. Although the percentage of fat in the American diet decreased, the percentage of carbohydrate and total calories increased, and sugar consumption skyrocketed. In The Low-Fat Lie: Rise of Obesity, Diabetes, and Inflammation, Dr. Glen Lawrence describes how the false condemnation of saturated fat arose from a misunderstanding of how our bodies regulate cholesterol. He explains how replacing saturated fat with vegetable oil stoked the fires of inflammation to cause pain and suffering, in addition to aggravating cancer, diabetes, and heart disease. The mainstream health and nutrition authorities have long cautioned against consuming too much sugar because of the risk of tooth decay. However, they refuse to indict sugar for the gross deterioration of the nation's health and continue to blame fat, especially saturated fat. Dr. Lawrence points out that a low-fat, high-carbohydrate diet is not as effective as a low-carbohydrate diet for long-term weight loss, yet the low-fat diet mantra continues to resonate from the halls of the agencies doling out dietary advice. He also describes how sugar consumption produces classic signs of addiction in lab animals, whereas high fat consumption does not. The food and beverage industries take advantage of this phenomenon and use aggressive marketing strategies to get children hooked on sugar at an early age. Understanding how we process what we put into our body can inform our decisions regarding dietary choices and a healthy lifestyle. Consuming more fiber in fruits and vegetables promotes a healthy microbiome, which is critical to overall health. The Low-Fat Lie also discusses: • many ways in which gut microbiota communicate with fat tissue and other organs, including via endocannabinoid signals; • active components of cannabis in the context of inflammation and pain; and • how stress can influence eating patterns, while exercise can help relieve stress and suppress or control detrimental eating behaviors. Dr. Lawrence does not prescribe any specific diet plan. Instead, he aims to enlighten the reader by illustrating the dire consequences of excessively sweetened and highly processed foods.

Weight Management

Author : Hubertus Himmerich
Publisher : BoD – Books on Demand
ISBN 13 : 1839625422
Total Pages : 333 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Weight Management by : Hubertus Himmerich

Download or read book Weight Management written by Hubertus Himmerich and published by BoD – Books on Demand. This book was released on 2020-09-09 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Weight management is a multi- and cross-disciplinary challenge. This book covers many etiological and diagnostic aspects of weight-related disorders and their treatment. This book explains how body weight influences and is influenced by the brain, hormones and immune system, diet, physical activity, posture and gait, and the social environment. This book also elucidates the health consequences of significantly low or pathologically increased body weight. Furthermore, ideas on how to influence and manage body weight including anti-obesity medical devices, diet counselling, artificial sweeteners, prebiotics and probiotics, proanthocyanidins, bariatric surgery, microbiota transplantation, warming, physical exercise, music and psychological therapy are discussed.

Obesity and Diabetes

Author : Joel Faintuch
Publisher : Springer
ISBN 13 : 3319131265
Total Pages : 286 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Obesity and Diabetes by : Joel Faintuch

Download or read book Obesity and Diabetes written by Joel Faintuch and published by Springer. This book was released on 2014-12-29 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely and clinically oriented book uniquely addresses the entire spectrum of treatment for severe obesity and diabetes. It thoroughly examines all aspects from robotic surgery to cell therapy, from the latest antidiabetic drugs to endoscopic procedures and devices, from appetite-inhibiting signals and nutrients to gastric arterial embolization. It offers objective and authoritative information for practicing professionals; not only are successful interventions discussed and updated, but cutting-edge and experimental pathways are also anticipated. Obesity is the foremost nutritional challenge worldwide. Its companion is type-2 diabetes, the most prevalent metabolic disease. Together they represent the diabesity epidemic, which is draining resources, overwhelming healthcare facilities, and impacting life expectancy and quality of life everywhere. No country has been spared, and most medical specialties have been affected. Many books focus on the surgical options for obesity and diabetes, namely bariatric and metabolic operations. Information on the clinical and pharmacological treatment is also available, conveyed by standard texts on internal medicine and endocrinology. Yet endoscopic maneuvers and prostheses, cell therapy for diabetes, and other innovative approaches are hard to come by, as conventional texts overlook such therapies. This timely publication bridges the gaps between all different therapeutic options, also covering advances in the conservative, surgical and parasurgical domains. This book will appeal to seasoned specialists, students and healthcare professionals in training alike.

Obesity, Inflammation and Cancer

Author : Andrew J. Dannenberg
Publisher : Springer Science & Business Media
ISBN 13 : 1461468191
Total Pages : 440 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Obesity, Inflammation and Cancer by : Andrew J. Dannenberg

Download or read book Obesity, Inflammation and Cancer written by Andrew J. Dannenberg and published by Springer Science & Business Media. This book was released on 2013-05-21 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: In addition to its metabolic and endocrinologic effects, obesity and adipose tissue have now been shown to be associated with low grade inflammation resulting in cellular and humoral inflammatory factors of which the latter may act by endocrine, paracrine and autocrine mechanisms. These inflammatory mediators have increasingly been suggested as contributing to the obesity link to carcinogenesis and cancer promotion. This volume of Energy Balance and Cancer will focus on recent developments and cutting edge research pointing to inflammation and inflammatory factors as key mediators of this linkage. The volume first provides information on inflammation as an important link between obesity and insulin resistance, which is in itself linked to promotion of cancer through hyperinsulinemia. The volume then covers some of the most important mechanisms by which obesity leads to inflammation, including the novel inflammasome concept, alterations in chromatin structure, circulating inflammatory factors, unique cellular interactions between adipocytes and macrophages and the direct link of dietary fat to inflammation and cancer. Overall, this volume will provide important insight to help understand how inflammation may help modulate the linkage between obesity and cancer and serve as a platform for developing future research in this area.

Obesity and Diabetes

Author : Anthony H. Barnett
Publisher : John Wiley & Sons
ISBN 13 : 0470011092
Total Pages : 324 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Obesity and Diabetes by : Anthony H. Barnett

Download or read book Obesity and Diabetes written by Anthony H. Barnett and published by John Wiley & Sons. This book was released on 2005-04-08 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity has become the most common chronic disease of the present day, with significant increases in prevalence in populations across the world and all age groups. This has resulted in a dramatic increase in obesity-related metabolic and cardiovascular complications, making it an important public health issue. Type 2 diabetes associated with obesity or 'diabesity' is today the most common form of type 2 diabetes. It is also associated with a number of other cardiovascular risk factors, which constitute the metabolic syndrome. Effective management of 'diabesity' is crucial to the reduction of morbidity and premature mortality due to cardiovascular disease. This book comprises chapters written by leading international experts on various aspects of obesity-related diabetes. As a practical reference guide, it is suitable for all professionals with an interest in this field. Emerging problems such as childhood 'diabesity' and the impact of obesity on polycystic ovary syndrome will be of interest not only to paediatricians and endocrinologists, but also to general practitioners and other healthcare professionals. The contemporary approach to the clinical assessment of obesity and its management in both primary and secondary care settings is also described.

Pathophysiology of Obesity-Induced Health Complications

Author : Paramjit S. Tappia
Publisher : Springer Nature
ISBN 13 : 3030353583
Total Pages : 348 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Pathophysiology of Obesity-Induced Health Complications by : Paramjit S. Tappia

Download or read book Pathophysiology of Obesity-Induced Health Complications written by Paramjit S. Tappia and published by Springer Nature. This book was released on 2020-01-17 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the World Health Organization, the epidemic of global obesity has nearly tripled since 1975. In 2016, more than 1.9 billion adults were overweight, over 650 million of which were obese. Being overweight and obese has been linked to a number of non-communicable, chronic diseases. Pathophysiology of Obesity-Induced Health Complications is a compilation of review articles dedicated to describe co-morbidities associated with obesity. The wide range that is covered is of significant interest to basic research scientists, clinicians and graduate students who are engaged in studying obesity-induced health complications. Furthermore, this book highlights the potential of novel approaches for the prevention and treatment of obesity and its related illnesses. Nineteen articles in this book are organized in four sections that are designed to provide an overview of obesity-induced health complications. The first section serves as an introductory section on the prevalence, causes, consequences, treatments and preventive approaches for obesity. Section two covers the metabolic disturbances and inflammation due to obesity. The third section is focused on neurological and visceral complications as a consequence of obesity. The final section covers strategies for the prevention of obesity-induced complications. The book illustrates that obesity can result in a diverse range of pathophysiological conditions that adversely affect health.

The Low-fat Lie

Author : Glen D. Lawrence
Publisher : Universal Publishers.com
ISBN 13 : 9781627342797
Total Pages : pages
Book Rating : 4.3/5 (427 download)

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Book Synopsis The Low-fat Lie by : Glen D. Lawrence

Download or read book The Low-fat Lie written by Glen D. Lawrence and published by Universal Publishers.com. This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book describes the impact the low-fat, low-saturated fat dietary recommendations have had on general health in the US, as well as world-wide. The recommendation to lower consumption of saturated fats had no scientific basis, and led to increased consumption of sugars and polyunsaturated oils, which both had dire consequences on not only obesity and diabetes, but inflammation and many related diseases"--

Nutritional Signaling Pathway Activities in Obesity and Diabetes

Author : Zhiyong Cheng
Publisher : Royal Society of Chemistry
ISBN 13 : 1788015576
Total Pages : 353 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Nutritional Signaling Pathway Activities in Obesity and Diabetes by : Zhiyong Cheng

Download or read book Nutritional Signaling Pathway Activities in Obesity and Diabetes written by Zhiyong Cheng and published by Royal Society of Chemistry. This book was released on 2020-09-04 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book disseminates the cutting-edge knowledge pertaining to nutritional signaling activities in obesity and diabetes, including the regulatory mechanisms and perspectives of nutritional interventions for disease prevention.

Obesity

Author : Amelia Marti del Moral
Publisher : Academic Press
ISBN 13 : 0128125055
Total Pages : 304 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Obesity by : Amelia Marti del Moral

Download or read book Obesity written by Amelia Marti del Moral and published by Academic Press. This book was released on 2018-08-10 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity: Oxidative Stress and Dietary Antioxidants cover the science of oxidative stress in obesity and associated conditions, including metabolic syndrome, bariatric surgery, and the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are not described in isolation, but in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is but a single component. The book is designed for nutritionists, dietitians, food scientists, physicians and clinical workers, health care workers and research scientists. Covers the basic processes of oxidative stress, from molecular biology, to whole organs Highlights antioxidants in foods, including plants and other components of diet Provides the framework for further, in-depth analysis or studies via well-designed clinical trials or via the analysis of pathways, mechanisms and componentsa

Adipose Tissue in Health and Disease

Author : Todd Leff
Publisher : John Wiley & Sons
ISBN 13 : 9783527629534
Total Pages : 530 pages
Book Rating : 4.6/5 (295 download)

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Book Synopsis Adipose Tissue in Health and Disease by : Todd Leff

Download or read book Adipose Tissue in Health and Disease written by Todd Leff and published by John Wiley & Sons. This book was released on 2010-03-19 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.