Nutrient-Gene Interactions in Cancer

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Publisher : CRC Press
ISBN 13 : 1000611337
Total Pages : 325 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Nutrient-Gene Interactions in Cancer by : Sang-Woon Choi

Download or read book Nutrient-Gene Interactions in Cancer written by Sang-Woon Choi and published by CRC Press. This book was released on 2006-01-24 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complete mapping of the human genome, along with the development of sophisticated molecular technologies, has accelerated research on the relationship between nutrients and genes. This has led to compelling evidence garnered from epidemiological and experimental observations supporting the idea that the interaction between nutrients and genes i

Nutrient-Gene Interactions in Health and Disease

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Publisher : CRC Press
ISBN 13 : 1000611302
Total Pages : 382 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Nutrient-Gene Interactions in Health and Disease by : Naima Moustaid-Moussa

Download or read book Nutrient-Gene Interactions in Health and Disease written by Naima Moustaid-Moussa and published by CRC Press. This book was released on 2001-05-30 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have come to realize that optimal nutrient intake is determined by very specific genetic messages. This realization has led to an entirely new approach to understanding nutrition - the exploration of nutrient effects on gene expression. Edited by leading experts in the field, Nutrient-Gene Interactions in Health and Disease provides an

Functional Foods in Cancer Prevention and Therapy

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Publisher : Academic Press
ISBN 13 : 0128161515
Total Pages : 522 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Functional Foods in Cancer Prevention and Therapy by : Yearul Kabir

Download or read book Functional Foods in Cancer Prevention and Therapy written by Yearul Kabir and published by Academic Press. This book was released on 2020-04-07 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Foods in Cancer Prevention and Therapy presents the wide range of functional foods associated with the prevention and treatment of cancer. In recent decades, researchers have made progress in our understanding of the association between functional food and cancer, especially as it relates to cancer treatment and prevention. Specifically, substantial evidence from epidemiological, clinical and laboratory studies show that various food components may alter cancer risk, the prognosis after cancer onset, and the quality of life after cancer treatment. The book documents the therapeutic roles of well-known functional foods and explains their role in cancer therapy. The book presents complex cancer patterns and evidence of the effective ways to control cancers with the use of functional foods. This book will serve as informative reference for researchers focused on the role of food in cancer prevention and physicians and clinicians involved in cancer treatment. Discusses the role of functional foods in cancer therapy Presents research-based evidence of the role of herbs and bioactive foods in cancer treatment and prevention Provides the most current, concise, scientific information regarding the efficacy of functional foods in preventing cancer and improving the quality of life Explores antioxidants, phytochemicals, nutraceuticals, herbal medicine and supplements in relation to cancer prevention and treatment Contains a clinical approach to the use of functional foods to prevent and treat cancer Emphasizes the role and mechanism of functional foods, including the characterization of active compounds on cancer prevention and treatment

Nutritional Genomics

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Publisher : John Wiley & Sons
ISBN 13 : 0471781789
Total Pages : 506 pages
Book Rating : 4.4/5 (717 download)

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Book Synopsis Nutritional Genomics by : Jim Kaput

Download or read book Nutritional Genomics written by Jim Kaput and published by John Wiley & Sons. This book was released on 2006-04-28 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive guide to the basic principles and latest advances in Nutritional Genomics Though still in its infancy, nutritional genomics, or "nutrigenomics," has revealed much about the complex interactions between diet and genes. But it is in its potential applications that nutrigenomics promises to revolutionize the ways we manage human health and combat disease in the years ahead. Great progress already has been made in modeling "personalized" nutrition for optimal health and longevity as well as in genotype-based dietary interventions for the prevention, mitigation, or possible cure of a variety of chronic diseases and some types of cancer. Topics covered include: * Nutrients and gene expression * The role of metabolomics in individualized health * Molecular mechanisms of longevity regulation and calorie restriction * Green tea polyphenols and soy peptides in cancer prevention * Maternal nutrition and fetal gene expression * Genetic susceptibility to heterocyclic amines from cooked foods * Bioinformatics and biocomputation in nutrigenomics * The pursuit of optimal diets Written by an all-star team of experts from around the globe, this volume provides an integrated overview of the cutting-edge field of nutritional genomics. The authors and editors lead an in-depth discussion of the fundamental principles and scientific methodologies that serve as the foundation for nutritional genomics and explore important recent advances in an array of related disciplines. Each self-contained chapter builds upon its predecessor, leading the reader seamlessly from basic principles to more complex scientific findings and experimental designs. Scientific chapters are carefully balanced with those addressing the social, ethical, regulatory, and commercial implications of nutrigenomics.

Phytochemicals

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Publisher : CRC Press
ISBN 13 : 1420005901
Total Pages : 232 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Phytochemicals by : Mark S. Meskin

Download or read book Phytochemicals written by Mark S. Meskin and published by CRC Press. This book was released on 2006-02-22 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding phytochemical–gene interactions provides the basis for individualized therapies to promote health as well as prevent and treat disease. The authors of Phytochemicals: Nutrient–Gene Interactions examine the interactions between phytochemicals and the human genome and discuss the impact these interactions have on health, aging, and chronic conditions such as inflammation, heart disease, obesity, type II diabetes mellitus, and cancer. Keeping pace with the most important trends in phytochemical research, the authors accentuate the latest understanding on the use of controlled clinical trials, new screening technologies, and the completed human genome project for researching the pharmacokinetics, safety, and efficacy of phytochemicals. The book covers a balanced range of topics beginning with experimental strategies and methodologies for identifying significant interactions between diet, genetic variants, and different markers of cardiovascular disease, inflammation, and obesity. Different authors explain the mechanisms of protective action that link diets rich in omega-3 fatty acids, unsaturated fats, fruits, vegetables, and whole grains with a decreased risk of chronic and degenerative diseases. They also review and summarize epidemiological research on plant-based foods and dietary patterns supporting the beneficial role of phytochemicals in health promotion and disease prevention. Phytochemicals: Nutrient–Gene Interactions illustrates the growing role of nutrigenomics and nutrigenetics in disease prevention and in the responsible development of safe and effective phytochemical products within the food, pharmaceutical, and supplement industries.

Nutritional Oncology

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Publisher : Elsevier
ISBN 13 : 0080454178
Total Pages : 847 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Nutritional Oncology by : George L. Blackburn

Download or read book Nutritional Oncology written by George L. Blackburn and published by Elsevier. This book was released on 2011-05-02 with total page 847 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutritional oncology is an increasingly active interdisciplinary field where cancer is investigated as both a systemic and local disease originating with the changes in the genome and progressing through a multi-step process which may be influenced at many points in its natural history by nutritional factors that could impact the prevention of cancer, the quality of life of cancer patients, and the risk of cancer recurrence in the rapidly increasing population of cancer survivors.Since the first edition of this book was published in 1999, the idea that there is a single gene pathway or single drug will provide a cure for cancer has given way to the general view that dietary/environmental factors impact the progression of genetic and cellular changes in common forms of cancer. This broad concept can now be investigated within a basic and clinical research context for specific types of cancer. This book attempts to cover the current available knowledge in this new field of nutritional oncology written by invited experts. This book attempts to provide not only the theoretical and research basis for nutritional oncology, but will offer the medical oncologist and other members of multidisciplinary groups treating cancer patients practical information on nutrition assessment and nutritional regimens, including micronutrient and phytochemical supplementation. The editors hope that this volume will stimulate increased research, education and patient application of the principles of nutritional oncology.NEW TO THIS EDITION:* Covers hot new topics of nutrigenomics and nutrigenetics in cancer cell growth * Includes new chapters on metabolic networks in cancer cell growth, nutrigenetics and nutrigenomics* Presents substantially revised chapters on breast cancer and nutrition, prostate cancer and nutrition, and colon cancer and nutrition* Includes new illustrations throughout the text, especially in the breast cancer chapter * Includes integrated insights into the unanswered questions and clearly defined objectives of research in nutritional oncology * Offers practical guidelines for clinicians advising malnourished cancer patients and cancer survivors on diet, nutrition, and lifestyle * Provides information on the role of bioactive substances, dietary supplements, phytochemicals and botanicals in cancer prevention and treatment

Nutrigenomics and Proteomics in Health and Disease

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Publisher : John Wiley & Sons
ISBN 13 : 0813807174
Total Pages : 413 pages
Book Rating : 4.8/5 (138 download)

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Book Synopsis Nutrigenomics and Proteomics in Health and Disease by : Yoshinori Mine

Download or read book Nutrigenomics and Proteomics in Health and Disease written by Yoshinori Mine and published by John Wiley & Sons. This book was released on 2009-04-13 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Functional Food Science and Technology book series (Series Editor: Fereidoon Shahidi), this book compiles the current science based upon nutrigenomics and proteomics in food and health. Coverage includes many important nutraceuticals (food factors) and their impact on gene interaction and health. Authored by a stellar international team of multidisciplinary researchers, this book acquaints food and nutrition professionals with these new fields of nutrition research and conveys the state of the science to date.

Nutrigenomics and the Future of Nutrition

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Publisher : National Academies Press
ISBN 13 : 0309477646
Total Pages : 155 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Nutrigenomics and the Future of Nutrition by : National Academies of Sciences, Engineering, and Medicine

Download or read book Nutrigenomics and the Future of Nutrition written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-08-27 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: On December 5, 2017, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop titled Nutrigenomics and the Future of Nutrition in Washington, DC, to review current knowledge in the field of nutrigenomics as it relates to nutrition. Workshop participants explored the influence of genetic and epigenetic expression on nutritional status and the potential impact of personalized nutrition on health maintenance and chronic disease prevention. This publication summarizes the presentations and discussions from the workshop.

Nutritional Genomics

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Publisher : John Wiley & Sons
ISBN 13 : 3527607757
Total Pages : 470 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Nutritional Genomics by : Regina Brigelius-Flohé

Download or read book Nutritional Genomics written by Regina Brigelius-Flohé and published by John Wiley & Sons. This book was released on 2006-08-21 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutritional genomics paves the way for novel applications in medicine and human nutrition, and this volume presents the latest data on how genetic variation is associated with dietary response and how nutrients influence gene expression. In so doing, it brings together the various disciplines involved in this field of research, making this essential reading for nutritionists, biochemists and molecular biologists.

The Heterogeneity of Cancer Metabolism

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Publisher : Springer Nature
ISBN 13 : 303065768X
Total Pages : 283 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer Nature. This book was released on 2021-05-20 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume will introduce recent discoveries in cancer metabolism since the publication of the first edition in 2018, providing readers with an up-to-date understanding of developments in the field. Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, the authors delve into the complexity and diversity of cancer metabolism and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies for cancer treatment. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer treatment. This book has four major parts. Part one will cover the basic metabolism of cancer cells, followed by a discussion of the heterogeneity of cancer metabolism in part two. Part three addresses the relationship between cancer cells and cancer-associated fibroblasts, and the new part four will explore the metabolic interplay between cancer and other diseases. This new section makes the book unique from other texts currently available on the market. The second edition will be useful for cancer metabolism researchers, cancer biologists, epidemiologists, physicians, health care professionals in related disciplines, policymakers, marketing and economic strategists, among others. It may also be used in courses such as intro to cancer metabolism, cancer biology, and related biochemistry courses for undergraduate and graduate students.

Cancer and the Environment

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Publisher : National Academies Press
ISBN 13 : 0309169240
Total Pages : 160 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cancer and the Environment by : Institute of Medicine

Download or read book Cancer and the Environment written by Institute of Medicine and published by National Academies Press. This book was released on 2002-08-01 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Roundtable on Environmental Health Sciences, Research, and Medicine wanted to address the link between environmental factors and the development of cancer in light of recent advances in genomics. They asked what research tools are needed, how new scientific information can be applied in a timely manner to reduce the burden of cancer, and how this can be flexible enough to treat the individual.

Nutrigenomics and Beyond

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Publisher : National Academies Press
ISBN 13 : 0309179874
Total Pages : 90 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Nutrigenomics and Beyond by : Institute of Medicine

Download or read book Nutrigenomics and Beyond written by Institute of Medicine and published by National Academies Press. This book was released on 2007-06-28 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: The integration of biology, genomics, and health has opened the possibility of applying genomics technology to nutrition. In 2001, scientists associated with the Human Genome Project announced the successful mapping of the reference sequence of the human genome. Since then, a body of information has emerged. Genomics and related areas of research have contributed greatly to efforts to understand the cellular and molecular mechanisms underlying diet-disease relationships. Integration and application of genetic and genomics technology into nutrition research is, therefore, needed to develop nutrition research programs that are aimed at the prevention and control of chronic disease through genomics-based nutritional interventions. Of interest is the integration of relevant computational methods into nutritional genomics research; the enhancement of tools applicable to systems biology; and the effective dissemination of genomics-derived information to scientists, policy makers, and the interested public. To address these issues, a workshop was held on June 1 and 2, 2006. The workshop included presentations that were structured around three focus sessions: human genetic variation, epigenetics, and systems biology. A fourth session presented discussions on the implications of nutrigenomics for the future of nutrition science research. Numerous themes emerged from the workshop presentations. First, nutrigenomics is a complex field because it addresses issues related to multigenetic traits that can be modified by a number of nutritional and other environmental factors. Such complexity presents a challenge to the field; and the ensuing research opportunities will require cooperative work among scientific disciplines and across government, academic, and industrial centers, as well as adequate funding, to be realized. Additionally, the ability to stretch the limits of conventional research methodologies afforded by new genetic and genomic applications at the level of the individual opens the door to a wealth of potential benefits to areas such as disease prevention and wellness, bearing in mind the necessity of ethical safeguards. This potential, however, must be wisely exploited to avoid the pitfalls of overpromising research results and prematurely setting unrealistic expectations for beneficial outcomes. Finally, careful and rigorous research must be employed to optimize outcomes and assure acceptance by the scientific community. In summary, nutrition science is uniquely poised to serve as the crossroads for many disciplines and, using genomics tools, can bring this knowledge together to better understand and address diet-related chronic diseases and molecular responses to dietary factors.

Cancer Treatment

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Publisher : BoD – Books on Demand
ISBN 13 : 9535110985
Total Pages : 632 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Cancer Treatment by : Letícia Rangel

Download or read book Cancer Treatment written by Letícia Rangel and published by BoD – Books on Demand. This book was released on 2013-05-09 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Treatment: Conventional and Innovative Approaches is an attempt to integrate into a book volume the various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field. The volume is presented in six sections: i) Section 1: Cancer treatment: Conventional and innovative pharmacological approaches; ii) Section 2: Combinatorial strategies to fight cancer: Surgery, radiotherapy, backytherapy, chemotherapy, and hyperthermia; iii) Section 3: The immunotherapy of cancer; iv) Section 4: Multidisciplinarity in cancer therapy: nutrition and beyond; v) Section 5: Supportive care for cancer patients; vi) Section 6: Perspectives in cancer biology and modeling. Ultimately, we hope this book can enlighten important issues involved in the management of cancer, summarizing the state-of-the-art knowledge regarding the disease control and treatment; thus, providing means to improve the overall care of patients that daily battle against this potentially lethal condition.

Nutrient-Drug Interactions

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Publisher : CRC Press
ISBN 13 : 1420019139
Total Pages : 352 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Nutrient-Drug Interactions by : Kelly Anne Meckling

Download or read book Nutrient-Drug Interactions written by Kelly Anne Meckling and published by CRC Press. This book was released on 2006-06-23 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current research has given us a more complete understanding of how the chemicals in foods and herbs interact with natural and synthetic drugs. In some cases a single food or supplement can profoundly increase or decrease the toxicity and/or efficacy of a single drug. Although it is standard practice to examine the effects of food consumption on the absorption and pharmacokinetics of new drugs, the issue has become greater than "should this medicine be taken with or without food." Nutrient-Drug Interactions focuses on food, herbals, and their chemical constituents as contributors to human health through control of metabolism, primarily as they relate to chronic disease development and treatment. The book's organization highlights the ailment being treated or prevented and the targets of therapy. Each chapter provides a comprehensive examination of the macronutrient, micronutrient, and phytochemical impact on drug action and includes advice on modification or supplementation in those cases where diet is a factor. The chapters focus on the molecular mechanism by which a food or chemical is thought to modify disease process and drug behavior. The book describes the roles of genetic variation and polymorphism in determining nutrient/drug responses, how they might be "profiled" to identify those likely to demonstrate specific interactions, and who would benefit from adjuvant or complementary therapies. The book explores how what is consumed affects response, whether on a population or individual level, to the pharmacologic agents that are the mainstay of chronic disease treatment/prevention around the world.

Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods

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Publisher : John Wiley & Sons
ISBN 13 : 1118930428
Total Pages : 685 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods by : Debasis Bagchi

Download or read book Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods written by Debasis Bagchi and published by John Wiley & Sons. This book was released on 2015-10-12 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional foods and nutraceuticals have received considerable interest in the past decade largely due to increasing consumer awareness of the health benefits associated with food. Diet in human health is no longer a matter of simple nutrition: consumers are more proactive and increasingly interested in the health benefits of functional foods and their role in the prevention of illness and chronic conditions. This, combined with an aging population that focuses not only on longevity but also quality of life, has created a market for functional foods and nutraceuticals. A fully updated and revised second edition, Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods reflects the recent upsurge in "omics" technologies and features 48 chapters that cover topics including genomics, proteomics, metabolomics, epigenetics, peptidomics, nutrigenomics and human health, transcriptomics, nutriethics and nanotechnology. This cutting-edge volume, written by a panel of experts from around the globe reviews the latest developments in the field with an emphasis on the application of these novel technologies to functional foods and nutraceuticals.

Nutrigenomics and Proteomics in Health and Disease

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Publisher : John Wiley & Sons
ISBN 13 : 1119101255
Total Pages : 344 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Nutrigenomics and Proteomics in Health and Disease by : Martin Kussmann

Download or read book Nutrigenomics and Proteomics in Health and Disease written by Martin Kussmann and published by John Wiley & Sons. This book was released on 2017-03-21 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in a revised second edition, Nutrigenomics and Proteomics in Health and Disease brings together the very latest science based upon nutrigenomics and proteomics in food and health. Coverage includes many important nutraceuticals and their impact on gene interaction and health. Authored by an international team of multidisciplinary researchers, this book acquaints food and nutrition professionals with these new fields of nutrition research and conveys the state of the science to date. Thoroughly updated to reflect the most current developments in the field, the second edition includes six new chapters covering gut health and the personal microbiome; gut microbe-derived bioactive metabolites; proteomics and peptidomics in nutrition; gene selection for nutrigenomic studies; gene-nutrient network analysis, and nutrigenomics to nutritional systems biology. An additional five chapters have also been significantly remodelled. The new text includes a rethinking of in vitro and in vivo models with regard to their translatability into human phenotypes, and normative science methods and approaches have been complemented by more comprehensive systems biology-based investigations, deploying a multitude of omic platforms in an integrated fashion. Innovative tools and methods for statistical treatment and biological network analysis are also now included.

Diet and Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 1489909494
Total Pages : 230 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Diet and Cancer by : Maryce M. Jacobs

Download or read book Diet and Cancer written by Maryce M. Jacobs and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fifth of the annual research conferences of the American Institute for Cancer Research was held September l-2, 1994, at the L'Enfant Plaza Hotel in Washington, DC. Appropriately, in view of current directions in research, the theme was "Diet and Cancer: Molecular Mechanisms of Interactions". This proceedings volume contains chapters from the platform presentations and abstracts from the poster session held on the end of the first day. The subtopics for the tl;rree sessions held were "Retinoids, Vitamins A and Din Cancer Prevention and Therapy," "Choline and Lipids: Signal Transduction, Gene Expression and Growth Regulation," and "Dietary Factors and Regulation of Oncogenes, Growth and Differentiation. " A general overview on vitamins A and D emphasized that A and D, in addition to their established roles in vision, reproduction, and bone mineral homeostasis, may play significant roles in regulating cell function. Vitamin A metabolites, trans-retinoic acid and 9-cis-retinoic acid, regulate growth and differentiation. Furthermore, vitamin A deprived animals were more susceptible to both spontaneous and carcinogen-induced tumors. Epidemiological studies showed a correlation between low A intake and higher incidences of certain types of human cancers. Conversely, all-trans retinoic acid is useful in treatment and control of certain types of cancer. Physiologically, Vitamin D is converted to the active form, l ,25-dihydroxyvitamin D (VD). VD regulates hormone production and secretion, myocardial contractility, vascu 3 3 3 lar tone, and growth inhibition and differentiation.