NTP Workshop on Validation and Regulatory Acceptance of Alternative Toxicological Test Methods

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Publisher :
ISBN 13 : 9780788142338
Total Pages : 41 pages
Book Rating : 4.1/5 (423 download)

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Book Synopsis NTP Workshop on Validation and Regulatory Acceptance of Alternative Toxicological Test Methods by : Kenneth Olden

Download or read book NTP Workshop on Validation and Regulatory Acceptance of Alternative Toxicological Test Methods written by Kenneth Olden and published by . This book was released on 1997-02 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the NTP Workshop on Validation & Regulatory Acceptance of Alternative Toxicological Test Methods was to receive comments & recommendations from the public & invited experts on their draft report. It provided recommended criteria & processes for the validation & regulatory acceptance of new & revised toxicological testing methods. This report is a summary of the recommend. developed by the workshop participants. One of the goals of the NTP is developing & validating improved alternative toxicological test methods. The NTP Revit. Act directed NIEHS to: establish criteria for the validation & regulatory acceptance of alternative testing methods: & to recommend a process through which scientifically validated alternative methods can be accepted for regulatory use.

Validation and Regulatory Acceptance of Toxicological Test Methods

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Publisher : DIANE Publishing
ISBN 13 : 0788142321
Total Pages : 95 pages
Book Rating : 4.7/5 (881 download)

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Book Synopsis Validation and Regulatory Acceptance of Toxicological Test Methods by : DIANE Publishing Company

Download or read book Validation and Regulatory Acceptance of Toxicological Test Methods written by DIANE Publishing Company and published by DIANE Publishing. This book was released on 1998-02 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Federal Register

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ISBN 13 :
Total Pages : 420 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Federal Register by :

Download or read book Federal Register written by and published by . This book was released on 2013-11 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Annual Plan for Fiscal Year ...

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ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Annual Plan for Fiscal Year ... by : National Toxicology Program (U.S.)

Download or read book Annual Plan for Fiscal Year ... written by National Toxicology Program (U.S.) and published by . This book was released on 1990 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicity Assessment Alternatives

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Publisher : Springer Science & Business Media
ISBN 13 : 1592597181
Total Pages : 257 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Toxicity Assessment Alternatives by : Harry Salem

Download or read book Toxicity Assessment Alternatives written by Harry Salem and published by Springer Science & Business Media. This book was released on 1999-07-02 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicity Assessment Alternatives: Methods, Issues, Opportunities contains a broad array of critical surveys, contributed by active and respected investigators, describing their research and offering updates on toxicity assessment alternatives, directions determined by current and future grant programs, opportunities for mechanistically based test methods to detect endocrine disruptor activity, the use of alternatives in the Department of Defense hazard assessment initiatives, and the issues and opportunities for validation and regulatory acceptance. Several of these advances make use oftransgenic models that reduce the time and cost of carcinogenicity testing. Others use tissue cultures for the assessment of endocrine disrupting chemicals. Cultures of human epidermal keratinocytes are applicable as models for sulfur mustard lesions, and in vitro protein denaturation is used as a chemical test for assessing the ocular and dermal irritation potential of cosmetic prod ucts. Molecular modeling is applied to explaining chemical toxicity. Commercially developed assay systems have undergone extensive evaluation by their manufacturers. Some of these await external valida tion, and others await acceptance by North American and European regulatory agencies. Toxicity Assessment Alternatives: Methods, Issues, Opportunities provides information from members of the scientific and regulatory communities on what has been achieved and what has been accepted in alternatives to animal testing.

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1998

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Publisher :
ISBN 13 :
Total Pages : 1626 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1998 by :

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1998 written by and published by . This book was released on 1997 with total page 1626 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Validation and Regulatory Acceptance of Toxicological Test Methods

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Publisher :
ISBN 13 :
Total Pages : 130 pages
Book Rating : 4.E/5 ( download)

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Download or read book Validation and Regulatory Acceptance of Toxicological Test Methods written by and published by . This book was released on 1997 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Molecular Toxicology

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Publisher : VSP
ISBN 13 : 9789067642781
Total Pages : 590 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Advances in Molecular Toxicology by : Claude Reiss

Download or read book Advances in Molecular Toxicology written by Claude Reiss and published by VSP. This book was released on 1998-02 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular toxicology is on the way to setting a new standard in toxic risk assessment, with the powerful help of concepts and methods developed in the fields of molecular and cellular biology. The methods of molecular toxicology are endowed with qualities not always secured in more traditional approaches to toxicity assessment. These methods are easily standardized, reliable, reproducible and require only tiny amounts of the xenobiotic. They are much simpler, faster and less costly than current tests on animals and can be implemented with modest laboratory resources. This volume of Advances in Molecular Toxicology represents a collection of invited papers presented at the First European Workshop on Molecular Toxicology in Sophia Antipolis, France, The book covers 8 selected topics in molecular toxicology. The first two are devoted to ''physics'', dealing respectively with advanced instrumentation enabling location and quantification of xenobiotics in cells and organs with ultimate precision, and computer-assisted assessment of risk (QSAR). A comprehensive and up-to-date survey of molecular toxicology in the pharmaceutical industry is contributed by a pioneer in this field. The third section addresses the effect of xenobiotics on cell-cycle actors. Sections 4--6 deal with molecular toxicology in skin, kidney, nerve, liver and pancreatic cells. The last two sections describe methods to probe DNA damage and repair, and immunotoxicity.

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1999

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ISBN 13 :
Total Pages : 1556 pages
Book Rating : 4.0/5 (18 download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1999 by : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1999 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 1998 with total page 1556 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Animal Welfare Information Center Newsletter

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Publisher :
ISBN 13 :
Total Pages : 84 pages
Book Rating : 4.U/5 (183 download)

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Book Synopsis Animal Welfare Information Center Newsletter by :

Download or read book Animal Welfare Information Center Newsletter written by and published by . This book was released on 1997 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Departments of Labor, Health and Human Services, and Education, and Related Agencies Appropriations for Fiscal Year 1998

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Publisher :
ISBN 13 :
Total Pages : 712 pages
Book Rating : 4.:/5 (51 download)

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Book Synopsis Departments of Labor, Health and Human Services, and Education, and Related Agencies Appropriations for Fiscal Year 1998 by : United States. Congress. Senate. Committee on Appropriations. Subcommittee on Departments of Labor, Health and Human Services, Education, and Related Agencies

Download or read book Departments of Labor, Health and Human Services, and Education, and Related Agencies Appropriations for Fiscal Year 1998 written by United States. Congress. Senate. Committee on Appropriations. Subcommittee on Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 1998 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neurotoxicology in Vitro

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Publisher : CRC Press
ISBN 13 : 9780748403882
Total Pages : 314 pages
Book Rating : 4.4/5 (38 download)

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Book Synopsis Neurotoxicology in Vitro by : V. Pentreath

Download or read book Neurotoxicology in Vitro written by V. Pentreath and published by CRC Press. This book was released on 1999-05-27 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a distinguished panel of experts, students and researchers will find that this comprehensive and accessible volume provides a framework for the study of nerve cells ^in vitro^n for use in experimental neurotoxicology.

NTP, Current Directions and Evolving Strategies

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ISBN 13 :
Total Pages : 36 pages
Book Rating : 4.:/5 (9 download)

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Book Synopsis NTP, Current Directions and Evolving Strategies by : National Toxicology Program (U.S.)

Download or read book NTP, Current Directions and Evolving Strategies written by National Toxicology Program (U.S.) and published by . This book was released on 2000 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2011, Part 2A, 111-2 Hearings

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ISBN 13 :
Total Pages : 1822 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2011, Part 2A, 111-2 Hearings by :

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2011, Part 2A, 111-2 Hearings written by and published by . This book was released on 2010 with total page 1822 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2011

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ISBN 13 :
Total Pages : 1830 pages
Book Rating : 4.:/5 (53 download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2011 by : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2011 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 2010 with total page 1830 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Reviews in Environmental Health, 1998 ; Toxicological Defense Mechanisms

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ISBN 13 :
Total Pages : 428 pages
Book Rating : 4.3/5 ( download)

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Download or read book Reviews in Environmental Health, 1998 ; Toxicological Defense Mechanisms written by and published by . This book was released on 1998 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Alternative Toxicological Methods

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Publisher : CRC Press
ISBN 13 : 0203008790
Total Pages : 616 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Alternative Toxicological Methods by : Harry Salem

Download or read book Alternative Toxicological Methods written by Harry Salem and published by CRC Press. This book was released on 2003-03-26 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together the recent and relevant contributions of over 125 scientists from industry, government, and academia in North America and Western Europe, Alternative Toxicological Methods explores the development and validation of replacement, reduction, and refinement alternatives (the 3Rs) to animal testing. Internationally recognized scientist