Ntp Report On The Toxicology Studies Of Acesulfame Potassium Cas No 55589 62 3 In Genetically Modified Fvb Tg Ac Hemizygous Mice And Carcinogenicity Studies Of Acesulfame Potassium In Genetically Modified B6129 Trp53tm1brd N5 Haploinsufficient Mice Feed Studies

Author :
Publisher :
ISBN 13 :
Total Pages : 114 pages
Book Rating : 4.:/5 (129 download)

DOWNLOAD NOW!

Download or read book NTP Report on the Toxicity Studies of Acesulfame Potassium (CAS NO. 55589-62-3) in FVB/N-TgN(v-Ha-ras)Led (Tg.AC) Hemizygous Mice and Carcinogenicity Studies of Acesulfame Potassium in B6.129-Trp53tm1Brd (N5) Haploinsufficient Mice (Feed Studies) written by and published by . This book was released on 2005 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: BACKGROUND: Acesulfame potassium is an artificial sweetener widely used in beverages and foods. We tested if acesulfame potassium could cause cancer in two different strains of genetically modified mice. METHODS: We fed groups of male and female Tg.AC mice and male and female p53 mice diets containing up to 3% acesulfame potassium for 9 months. Animals given feed with no sweetener added served as the control groups. Tissues from 15 sites were examined for every animal. RESULTS: Exposure to acesulfame potassium had no effect on the survival of any of the animal groups. No increases in tumors were seen in males or females from either strain of mice. CONCLUSIONS: We conclude that acesulfame potassium did not cause cancer in the genetically modified mice used in these studies.